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The matrikine N-α-PGP couples extracellular matrix fragmentation to endothelial permeability.

Hahn CS, Scott DW, Xu X, Roda MA, Payne GA, Wells JM, Viera L, Winstead CJ, Bratcher P, Sparidans RW, Redegeld FA, Jackson PL, Folkerts G, Blalock JE, Patel RP, Gaggar A.

Sci Adv. 2015;1(3). pii: e1500175.


Predicting storage-dependent damage to red blood cells using nitrite oxidation kinetics, peroxiredoxin-2 oxidation, and hemoglobin and free heme measurements.

Oh JY, Stapley R, Harper V, Marques MB, Patel RP.

Transfusion. 2015 Jul 22. doi: 10.1111/trf.13248. [Epub ahead of print]


A Nitric Oxide-Releasing Self-Assembled Peptide Amphiphile Nanomatrix for Improving the Biocompatibility of Microporous Hollow Fibers.

El-Ferzli GT, Andukuri A, Alexander G, Scopel M, Ambalavanan N, Patel RP, Jun HW.

ASAIO J. 2015 Sep-Oct;61(5):589-95. doi: 10.1097/MAT.0000000000000257.


Red blood cell washing, nitrite therapy, and antiheme therapies prevent stored red blood cell toxicity after trauma-hemorrhage.

Stapley R, Rodriguez C, Oh JY, Honavar J, Brandon A, Wagener BM, Marques MB, Weinberg JA, Kerby JD, Pittet JF, Patel RP.

Free Radic Biol Med. 2015 Aug;85:207-18. doi: 10.1016/j.freeradbiomed.2015.04.025. Epub 2015 Apr 29.


Working with nitric oxide and hydrogen sulfide in biological systems.

Yuan S, Patel RP, Kevil CG.

Am J Physiol Lung Cell Mol Physiol. 2015 Mar 1;308(5):L403-15. doi: 10.1152/ajplung.00327.2014. Epub 2014 Dec 30. Review.


Nitrite therapy improves survival postexposure to chlorine gas.

Honavar J, Doran S, Oh JY, Steele C, Matalon S, Patel RP.

Am J Physiol Lung Cell Mol Physiol. 2014 Dec 1;307(11):L888-94. doi: 10.1152/ajplung.00079.2014. Epub 2014 Oct 17.


A novel model of chronic wounds: importance of redox imbalance and biofilm-forming bacteria for establishment of chronicity.

Dhall S, Do D, Garcia M, Wijesinghe DS, Brandon A, Kim J, Sanchez A, Lyubovitsky J, Gallagher S, Nothnagel EA, Chalfant CE, Patel RP, Schiller N, Martins-Green M.

PLoS One. 2014 Oct 14;9(10):e109848. doi: 10.1371/journal.pone.0109848. eCollection 2014.


Peroxiredoxin-2 recycling is inhibited during erythrocyte storage.

Harper VM, Oh JY, Stapley R, Marques MB, Wilson L, Barnes S, Sun CW, Townes T, Patel RP.

Antioxid Redox Signal. 2015 Feb 1;22(4):294-307. doi: 10.1089/ars.2014.5950. Epub 2014 Nov 10.


Formulation, optimization, and evaluation of a transdermal patch of heparin sodium.

Patel RP, Gaiakwad DR, Patel NA.

Drug Discov Ther. 2014 Aug;8(4):185-93.


Chlorine gas exposure disrupts nitric oxide homeostasis in the pulmonary vasculature.

Honavar J, Bradley E, Bradley K, Oh JY, Vallejo MO, Kelley EE, Cantu-Medellin N, Doran S, Dell'italia LJ, Matalon S, Patel RP.

Toxicology. 2014 Jul 3;321:96-102. doi: 10.1016/j.tox.2014.04.005. Epub 2014 Apr 24.


Increased sensitivity of Apolipoprotein E knockout mice to swainsonine dependent immunomodulation.

Scott DW, Black LL, Vallejo MO, Kabarowski JH, Patel RP.

Immunobiology. 2014 Jul;219(7):497-502. doi: 10.1016/j.imbio.2014.02.011. Epub 2014 Mar 2.


Redox therapeutics in hepatic ischemia reperfusion injury.

Patel RP, Lang JD, Smith AB, Crawford JH.

World J Hepatol. 2014 Jan 27;6(1):1-8. doi: 10.4254/wjh.v6.i1.1. Review.


A randomized clinical trial testing the anti-inflammatory effects of preemptive inhaled nitric oxide in human liver transplantation.

Lang JD Jr, Smith AB, Brandon A, Bradley KM, Liu Y, Li W, Crowe DR, Jhala NC, Cross RC, Frenette L, Martay K, Vater YL, Vitin AA, Dembo GA, Dubay DA, Bynon JS, Szychowski JM, Reyes JD, Halldorson JB, Rayhill SC, Dick AA, Bakthavatsalam R, Brandenberger J, Broeckel-Elrod JA, Sissons-Ross L, Jordan T, Chen LY, Siriussawakul A, Eckhoff DE, Patel RP.

PLoS One. 2014 Feb 12;9(2):e86053. doi: 10.1371/journal.pone.0086053. eCollection 2014.


Mechanism of faster NO scavenging by older stored red blood cells.

Liu C, Liu X, Janes J, Stapley R, Patel RP, Gladwin MT, Kim-Shapiro DB.

Redox Biol. 2014 Jan 10;2:211-9. doi: 10.1016/j.redox.2013.12.014. eCollection 2014.


The transcription factor E26 transformation-specific sequence-1 mediates neointima formation in arteriovenous fistula.

Feng W, Chumley P, Allon M, George J, Scott DW, Patel RP, Litovsky S, Jaimes EA.

J Am Soc Nephrol. 2014 Mar;25(3):475-87. doi: 10.1681/ASN.2013040424. Epub 2013 Nov 7.


The level of complement activation fragments is higher in red blood cell units than segments.

Hu X, Barnum SR, Patel RP, Marques MB, Weinberg JA.

Transfus Apher Sci. 2013 Dec;49(3):692-3. doi: 10.1016/j.transci.2013.10.001. Epub 2013 Oct 21. No abstract available.


The deleterious effect of red blood cell storage on microvascular response to transfusion.

Weinberg JA, MacLennan PA, Vandromme-Cusick MJ, Magnotti LJ, Kerby JD, Rue LW 3rd, Angotti JM, Garrett CA, Hendrick LE, Croce MA, Fabian TC, Barnum SR, Patel RP.

J Trauma Acute Care Surg. 2013 Nov;75(5):807-12. doi: 10.1097/TA.0b013e3182a74a9b.


Is methemoglobin an inert bystander, biomarker or a mediator of oxidative stress--The example of anemia?

Hare GM, Tsui AK, Crawford JH, Patel RP.

Redox Biol. 2013 Jan 26;1:65-9. doi: 10.1016/j.redox.2012.12.003. Review.


Heterogenic endothelial responses to inflammation: role for differential N-glycosylation and vascular bed of origin.

Scott DW, Vallejo MO, Patel RP.

J Am Heart Assoc. 2013 Jul 30;2(4):e000263. doi: 10.1161/JAHA.113.000263.

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