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Results: 1 to 20 of 36

1.

Anti-chondroitin sulfate proteoglycan 4-specific antibodies modify the effects of vemurafenib on melanoma cells differentially in normoxia and hypoxia.

Pucciarelli D, Lengger N, Takacova M, Csaderova L, Bartosova M, Breiteneder H, Pastorekova S, Hafner C.

Int J Oncol. 2015 Jul;47(1):81-90. doi: 10.3892/ijo.2015.3010. Epub 2015 May 18.

2.

Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy.

Pastorek M, Simko V, Takacova M, Barathova M, Bartosova M, Hunakova L, Sedlakova O, Hudecova S, Krizanova O, Dequiedt F, Pastorekova S, Sedlak J.

Int J Oncol. 2015 Jul;47(1):51-60. doi: 10.3892/ijo.2015.2987. Epub 2015 May 5.

3.

Carnosine inhibits carbonic anhydrase IX-mediated extracellular acidosis and suppresses growth of HeLa tumor xenografts.

Ditte Z, Ditte P, Labudova M, Simko V, Iuliano F, Zatovicova M, Csaderova L, Pastorekova S, Pastorek J.

BMC Cancer. 2014 May 22;14:358. doi: 10.1186/1471-2407-14-358.

4.

Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors.

Sedlakova O, Svastova E, Takacova M, Kopacek J, Pastorek J, Pastorekova S.

Front Physiol. 2014 Jan 8;4:400. doi: 10.3389/fphys.2013.00400. Review.

5.

The effect of carbonic anhydrase IX on focal contacts during cell spreading and migration.

Csaderova L, Debreova M, Radvak P, Stano M, Vrestiakova M, Kopacek J, Pastorekova S, Svastova E.

Front Physiol. 2013 Oct 1;4:271. doi: 10.3389/fphys.2013.00271. eCollection 2013.

6.

Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses.

Obacz J, Pastorekova S, Vojtesek B, Hrstka R.

Mol Cancer. 2013 Aug 14;12(1):93. doi: 10.1186/1476-4598-12-93. Review.

7.

Genotype and tumor locus determine expression profile of pseudohypoxic pheochromocytomas and paragangliomas.

Shankavaram U, Fliedner SM, Elkahloun AG, Barb JJ, Munson PJ, Huynh TT, Matro JC, Turkova H, Linehan WM, Timmers HJ, Tischler AS, Powers JF, de Krijger R, Baysal BE, Takacova M, Pastorekova S, Gius D, Lehnert H, Camphausen K, Pacak K.

Neoplasia. 2013 Apr;15(4):435-47.

8.

Carbonic anhydrase IX: a hypoxia-controlled "catalyst" of cell migration.

Svastova E, Pastorekova S.

Cell Adh Migr. 2013 Mar-Apr;7(2):226-31. doi: 10.4161/cam.23257. Epub 2013 Jan 9.

9.

Carbonic anhydrase IX is a clinically significant tissue and serum biomarker associated with renal cell carcinoma.

Takacova M, Bartosova M, Skvarkova L, Zatovicova M, Vidlickova I, Csaderova L, Barathova M, Breza J Jr, Bujdak P, Pastorek J, Breza J Sr, Pastorekova S.

Oncol Lett. 2013 Jan;5(1):191-197. Epub 2012 Oct 26.

10.

Carbonic anhydrase IX interacts with bicarbonate transporters in lamellipodia and increases cell migration via its catalytic domain.

Svastova E, Witarski W, Csaderova L, Kosik I, Skvarkova L, Hulikova A, Zatovicova M, Barathova M, Kopacek J, Pastorek J, Pastorekova S.

J Biol Chem. 2012 Jan 27;287(5):3392-402. doi: 10.1074/jbc.M111.286062. Epub 2011 Dec 14.

11.

Characterization of non-specific cytotoxic cell receptor protein 1: a new member of the lectin-type subfamily of F-box proteins.

Kallio H, Tolvanen M, Jänis J, Pan PW, Laurila E, Kallioniemi A, Kilpinen S, Tuominen VJ, Isola J, Valjakka J, Pastorekova S, Pastorek J, Parkkila S.

PLoS One. 2011;6(11):e27152. doi: 10.1371/journal.pone.0027152. Epub 2011 Nov 7.

12.

Hypoxia induces the gene expression and extracellular transmission of persistent lymphocytic choriomeningitis virus.

Tomaskova J, Oveckova I, Labudova M, Lukacikova L, Laposova K, Kopacek J, Pastorekova S, Pastorek J.

J Virol. 2011 Dec;85(24):13069-76. doi: 10.1128/JVI.00829-11. Epub 2011 Sep 28.

13.

PHD3 regulates differentiation, tumour growth and angiogenesis in pancreatic cancer.

Su Y, Loos M, Giese N, Hines OJ, Diebold I, Görlach A, Metzen E, Pastorekova S, Friess H, Büchler P.

Br J Cancer. 2010 Nov 9;103(10):1571-9. doi: 10.1038/sj.bjc.6605936. Epub 2010 Oct 26.

14.

The induction of S100p expression by the Prostaglandin E₂ (PGE₂)/EP4 receptor signaling pathway in colon cancer cells.

Chandramouli A, Mercado-Pimentel ME, Hutchinson A, Gibadulinová A, Olson ER, Dickinson S, Shañas R, Davenport J, Owens J, Bhattacharyya AK, Regan JW, Pastorekova S, Arumugam T, Logsdon CD, Nelson MA.

Cancer Biol Ther. 2010 Nov 15;10(10):1056-66. doi: 10.4161/cbt.10.10.13373. Epub 2010 Nov 15.

15.

The tumour-associated carbonic anhydrases CA II, CA IX and CA XII in a group of medulloblastomas and supratentorial primitive neuroectodermal tumours: an association of CA IX with poor prognosis.

Nordfors K, Haapasalo J, Korja M, Niemelä A, Laine J, Parkkila AK, Pastorekova S, Pastorek J, Waheed A, Sly WS, Parkkila S, Haapasalo H.

BMC Cancer. 2010 Apr 18;10:148. doi: 10.1186/1471-2407-10-148.

16.

Carbonic anhydrase II. A novel biomarker for gastrointestinal stromal tumors.

Parkkila S, Lasota J, Fletcher JA, Ou WB, Kivelä AJ, Nuorva K, Parkkila AK, Ollikainen J, Sly WS, Waheed A, Pastorekova S, Pastorek J, Isola J, Miettinen M.

Mod Pathol. 2010 May;23(5):743-50. doi: 10.1038/modpathol.2009.189. Epub 2010 Jan 15.

17.

Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX.

Alterio V, Hilvo M, Di Fiore A, Supuran CT, Pan P, Parkkila S, Scaloni A, Pastorek J, Pastorekova S, Pedone C, Scozzafava A, Monti SM, De Simone G.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16233-8. doi: 10.1073/pnas.0908301106. Epub 2009 Sep 14.

18.

Hypoxia-induced expression of carbonic anhydrase 9 is dependent on the unfolded protein response.

van den Beucken T, Koritzinsky M, Niessen H, Dubois L, Savelkouls K, Mujcic H, Jutten B, Kopacek J, Pastorekova S, van der Kogel AJ, Lambin P, Voncken W, Rouschop KM, Wouters BG.

J Biol Chem. 2009 Sep 4;284(36):24204-12. doi: 10.1074/jbc.M109.006510. Epub 2009 Jun 29.

19.

The nucleoprotein of lymphocytic choriomeningitis virus facilitates spread of persistent infection through stabilization of the keratin network.

Labudova M, Tomaskova J, Skultety L, Pastorek J, Pastorekova S.

J Virol. 2009 Aug;83(16):7842-9. doi: 10.1128/JVI.00309-09. Epub 2009 Jun 3.

20.

Hypoxia upregulates expression of human endosialin gene via hypoxia-inducible factor 2.

Ohradanova A, Gradin K, Barathova M, Zatovicova M, Holotnakova T, Kopacek J, Parkkila S, Poellinger L, Pastorekova S, Pastorek J.

Br J Cancer. 2008 Oct 21;99(8):1348-56. doi: 10.1038/sj.bjc.6604685. Epub 2008 Sep 23.

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