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Introduction: Great Institutions in Cardiothoracic Surgery.

Rosengart TK, Austin EH 3rd, Pass HI, Weisel RD.

Semin Thorac Cardiovasc Surg. 2015 Winter;27(4):339-40. doi: 10.1053/j.semtcvs.2015.12.007. Epub 2015 Dec 29. No abstract available.


DNA copy number gains in malignant pleural mesothelioma.

Furukawa M, Toyooka S, Hayashi T, Yamamoto H, Fujimoto N, Soh J, Hashida S, Shien K, Asano H, Aoe K, Okabe K, Pass HI, Tsukuda K, Kishimoto T, Miyoshi S.

Oncol Lett. 2015 Nov;10(5):3274-3278. Epub 2015 Aug 27.


Blinded Validation of Breath Biomarkers of Lung Cancer, a Potential Ancillary to Chest CT Screening.

Phillips M, Bauer TL, Cataneo RN, Lebauer C, Mundada M, Pass HI, Ramakrishna N, Rom WN, Vallières E.

PLoS One. 2015 Dec 23;10(12):e0142484. doi: 10.1371/journal.pone.0142484. eCollection 2015.


Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s.

Carbone M, Flores EG, Emi M, Johnson TA, Tsunoda T, Behner D, Hoffman H, Hesdorffer M, Nasu M, Napolitano A, Powers A, Minaai M, Baumann F, Bryant-Greenwood P, Lauk O, Kirschner MB, Weder W, Opitz I, Pass HI, Gaudino G, Pastorino S, Yang H.

PLoS Genet. 2015 Dec 18;11(12):e1005633. doi: 10.1371/journal.pgen.1005633. eCollection 2015 Dec.


Latest developments in our understanding of the pathogenesis of mesothelioma and the design of targeted therapies.

Bononi A, Napolitano A, Pass HI, Yang H, Carbone M.

Expert Rev Respir Med. 2015 Oct;9(5):633-54. doi: 10.1586/17476348.2015.1081066. Epub 2015 Aug 26.


Blood-based lung cancer biomarkers identified through proteomic discovery in cancer tissues, cell lines and conditioned medium.

Birse CE, Lagier RJ, FitzHugh W, Pass HI, Rom WN, Edell ES, Bungum AO, Maldonado F, Jett JR, Mesri M, Sult E, Joseloff E, Li A, Heidbrink J, Dhariwal G, Danis C, Tomic JL, Bruce RJ, Moore PA, He T, Lewis ME, Ruben SM.

Clin Proteomics. 2015 Jul 16;12(1):18. doi: 10.1186/s12014-015-9090-9. eCollection 2015.


Minimal asbestos exposure in germline BAP1 heterozygous mice is associated with deregulated inflammatory response and increased risk of mesothelioma.

Napolitano A, Pellegrini L, Dey A, Larson D, Tanji M, Flores EG, Kendrick B, Lapid D, Powers A, Kanodia S, Pastorino S, Pass HI, Dixit V, Yang H, Carbone M.

Oncogene. 2015 Jun 29. doi: 10.1038/onc.2015.243. [Epub ahead of print]


Aspirin delays mesothelioma growth by inhibiting HMGB1-mediated tumor progression.

Yang H, Pellegrini L, Napolitano A, Giorgi C, Jube S, Preti A, Jennings CJ, De Marchis F, Flores EG, Larson D, Pagano I, Tanji M, Powers A, Kanodia S, Gaudino G, Pastorino S, Pass HI, Pinton P, Bianchi ME, Carbone M.

Cell Death Dis. 2015 Jun 11;6:e1786. doi: 10.1038/cddis.2015.153.


A STAT3-NFkB/DDIT3/CEBPβ axis modulates ALDH1A3 expression in chemoresistant cell subpopulations.

Canino C, Luo Y, Marcato P, Blandino G, Pass HI, Cioce M.

Oncotarget. 2015 May 20;6(14):12637-53.


High Incidence of Somatic BAP1 alterations in sporadic malignant mesothelioma.

Nasu M, Emi M, Pastorino S, Tanji M, Powers A, Luk H, Baumann F, Zhang YA, Gazdar A, Kanodia S, Tiirikainen M, Flores E, Gaudino G, Becich MJ, Pass HI, Yang H, Carbone M.

J Thorac Oncol. 2015 Apr;10(4):565-76. doi: 10.1097/JTO.0000000000000471.


Metabolomic markers of altered nucleotide metabolism in early stage adenocarcinoma.

Wikoff WR, Grapov D, Fahrmann JF, DeFelice B, Rom WN, Pass HI, Kim K, Nguyen U, Taylor SL, Gandara DR, Kelly K, Fiehn O, Miyamoto S.

Cancer Prev Res (Phila). 2015 May;8(5):410-8. doi: 10.1158/1940-6207.CAPR-14-0329. Epub 2015 Feb 5.


Validation of a multiprotein plasma classifier to identify benign lung nodules.

Vachani A, Pass HI, Rom WN, Midthun DE, Edell ES, Laviolette M, Li XJ, Fong PY, Hunsucker SW, Hayward C, Mazzone PJ, Madtes DK, Miller YE, Walker MG, Shi J, Kearney P, Fang KC, Massion PP.

J Thorac Oncol. 2015 Apr;10(4):629-37. doi: 10.1097/JTO.0000000000000447.


Seminars in Thoracic and Cardiovascular Surgery. Introduction.

Pass HI, Rosengart TK.

Semin Thorac Cardiovasc Surg. 2014 Autumn;26(3):173. doi: 10.1053/j.semtcvs.2014.11.001. Epub 2014 Nov 11. No abstract available.


Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma.

Guo G, Chmielecki J, Goparaju C, Heguy A, Dolgalev I, Carbone M, Seepo S, Meyerson M, Pass HI.

Cancer Res. 2015 Jan 15;75(2):264-9. doi: 10.1158/0008-5472.CAN-14-1008. Epub 2014 Dec 8.


Evaluation of clonal origin of malignant mesothelioma.

Comertpay S, Pastorino S, Tanji M, Mezzapelle R, Strianese O, Napolitano A, Baumann F, Weigel T, Friedberg J, Sugarbaker P, Krausz T, Wang E, Powers A, Gaudino G, Kanodia S, Pass HI, Parsons BL, Yang H, Carbone M.

J Transl Med. 2014 Dec 4;12:301. doi: 10.1186/s12967-014-0301-3.


Surgical resection of non-small cell lung cancer with N2 disease.

Donington JS, Pass HI.

Thorac Surg Clin. 2014 Nov;24(4):449-56. doi: 10.1016/j.thorsurg.2014.07.010. Epub 2014 Sep 11. Review.


Methylation profile landscape in mesothelioma: possible implications in early detection, disease progression, and therapeutic options.

Zhang X, Tang N, Rishi AK, Pass HI, Wali A.

Methods Mol Biol. 2015;1238:235-47. doi: 10.1007/978-1-4939-1804-1_12. Review.


Treatment of recalcitrant subcutaneous emphysema using negative pressure wound therapy dressings.

Towe C, Solomon B, Donington JS, Pass HI.

BMJ Case Rep. 2014 Nov 9;2014. pii: bcr2014205577. doi: 10.1136/bcr-2014-205577.


Validation of a blood protein signature for non-small cell lung cancer.

Mehan MR, Williams SA, Siegfried JM, Bigbee WL, Weissfeld JL, Wilson DO, Pass HI, Rom WN, Muley T, Meister M, Franklin W, Miller YE, Brody EN, Ostroff RM.

Clin Proteomics. 2014 Aug 1;11(1):32. doi: 10.1186/1559-0275-11-32. eCollection 2014.


CREB-induced inflammation is important for malignant mesothelioma growth.

Westbom CM, Shukla A, MacPherson MB, Yasewicz EC, Miller JM, Beuschel SL, Steele C, Pass HI, Vacek PM, Shukla A.

Am J Pathol. 2014 Oct;184(10):2816-27. doi: 10.1016/j.ajpath.2014.06.008. Epub 2014 Aug 8.

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