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Results: 1 to 20 of 74

1.

Akt signaling leads to stem cell activation and promotes tumor development in epidermis.

Segrelles C, García-Escudero R, Garín MI, Aranda JF, Hernández P, Ariza JM, Santos M, Paramio JM, Lorz C.

Stem Cells. 2014 Jul;32(7):1917-28. doi: 10.1002/stem.1669.

PMID:
24504902
[PubMed - in process]
2.

Skin Tumors Rb(eing) Uncovered.

Costa C, Paramio JM, Santos M.

Front Oncol. 2013 Dec 17;3:307. doi: 10.3389/fonc.2013.00307. Review.

PMID:
24381932
[PubMed]
Free PMC Article
3.

PIK3CA gene alterations in bladder cancer are frequent and associate with reduced recurrence in non-muscle invasive tumors.

Dueñas M, Martínez-Fernández M, García-Escudero R, Villacampa F, Marqués M, Saiz-Ladera C, Duarte J, Martínez V, Gómez MJ, Martín ML, Fernández M, Castellano D, Real FX, Rodriguez-Peralto JL, De La Rosa F, Paramio JM.

Mol Carcinog. 2013 Dec 18. doi: 10.1002/mc.22125. [Epub ahead of print]

PMID:
24347284
[PubMed - as supplied by publisher]
4.

p21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia.

Saiz-Ladera C, Lara MF, Garín M, Ruiz S, Santos M, Lorz C, García-Escudero R, Martínez-Fernández M, Bravo A, Fernández-Capetillo O, Segrelles C, Paramio JM.

Oncogene. 2014 Sep 11;33(37):4599-612. doi: 10.1038/onc.2013.417. Epub 2013 Oct 14.

PMID:
24121270
[PubMed - in process]
5.

The Rho exchange factors Vav2 and Vav3 favor skin tumor initiation and promotion by engaging extracellular signaling loops.

Menacho-Márquez M, García-Escudero R, Ojeda V, Abad A, Delgado P, Costa C, Ruiz S, Alarcón B, Paramio JM, Bustelo XR.

PLoS Biol. 2013 Jul;11(7):e1001615. doi: 10.1371/journal.pbio.1001615. Epub 2013 Jul 23.

PMID:
23935450
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A novel tumor suppressor network in squamous malignancies.

Costa C, Santos M, Segrelles C, Dueñas M, Lara MF, Agirre X, Prosper F, García-Escudero R, Paramio JM.

Sci Rep. 2012;2:828. doi: 10.1038/srep00828. Epub 2012 Nov 9.

PMID:
23145321
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The rho exchange factors vav2 and vav3 control a lung metastasis-specific transcriptional program in breast cancer cells.

Citterio C, Menacho-Márquez M, García-Escudero R, Larive RM, Barreiro O, Sánchez-Madrid F, Paramio JM, Bustelo XR.

Sci Signal. 2012 Oct 2;5(244):ra71. doi: 10.1126/scisignal.2002962.

PMID:
23033540
[PubMed - indexed for MEDLINE]
Free Article
8.

Progeny of Lgr5-expressing hair follicle stem cell contributes to papillomavirus-induced tumor development in epidermis.

da Silva-Diz V, Solé-Sánchez S, Valdés-Gutiérrez A, Urpí M, Riba-Artés D, Penin RM, Pascual G, González-Suárez E, Casanovas O, Viñals F, Paramio JM, Batlle E, Muñoz P.

Oncogene. 2013 Aug 8;32(32):3732-43. doi: 10.1038/onc.2012.375. Epub 2012 Sep 3.

PMID:
22945646
[PubMed - indexed for MEDLINE]
9.

A humanized mouse model of HPV-associated pathology driven by E7 expression.

Buitrago-Pérez Á, Hachimi M, Dueñas M, Lloveras B, Santos A, Holguín A, Duarte B, Santiago JL, Akgül B, Rodríguez-Peralto JL, Storey A, Ribas C, Larcher F, del Rio M, Paramio JM, García-Escudero R.

PLoS One. 2012;7(7):e41743. doi: 10.1371/journal.pone.0041743. Epub 2012 Jul 23.

PMID:
22911850
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

E2F1 loss induces spontaneous tumour development in Rb-deficient epidermis.

Costa C, Santos M, Martínez-Fernández M, Dueñas M, Lorz C, García-Escudero R, Paramio JM.

Oncogene. 2013 Jun 13;32(24):2937-51. doi: 10.1038/onc.2012.316. Epub 2012 Aug 13.

PMID:
22890321
[PubMed - indexed for MEDLINE]
11.

Mouse p53-deficient cancer models as platforms for obtaining genomic predictors of human cancer clinical outcomes.

Dueñas M, Santos M, Aranda JF, Bielza C, Martínez-Cruz AB, Lorz C, Taron M, Ciruelos EM, Rodríguez-Peralto JL, Martín M, Larrañaga P, Dahabreh J, Stathopoulos GP, Rosell R, Paramio JM, García-Escudero R.

PLoS One. 2012;7(8):e42494. doi: 10.1371/journal.pone.0042494. Epub 2012 Aug 7.

PMID:
22880004
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The orphan receptor GPR55 drives skin carcinogenesis and is upregulated in human squamous cell carcinomas.

Pérez-Gómez E, Andradas C, Flores JM, Quintanilla M, Paramio JM, Guzmán M, Sánchez C.

Oncogene. 2013 May 16;32(20):2534-42. doi: 10.1038/onc.2012.278. Epub 2012 Jul 2.

PMID:
22751111
[PubMed - indexed for MEDLINE]
13.

EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours.

Bornachea O, Santos M, Martínez-Cruz AB, García-Escudero R, Dueñas M, Costa C, Segrelles C, Lorz C, Buitrago A, Saiz-Ladera C, Agirre X, Grande T, Paradela B, Maraver A, Ariza JM, Prosper F, Serrano M, Sánchez-Céspedes M, Paramio JM.

Sci Rep. 2012;2:434. doi: 10.1038/srep00434. Epub 2012 May 31.

PMID:
22666537
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion.

Ganuza M, Sáiz-Ladera C, Cañamero M, Gómez G, Schneider R, Blasco MA, Pisano D, Paramio JM, Santamaría D, Barbacid M.

EMBO J. 2012 May 30;31(11):2498-510. doi: 10.1038/emboj.2012.94. Epub 2012 Apr 13.

PMID:
22505032
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes.

Pippa R, Espinosa L, Gundem G, García-Escudero R, Dominguez A, Orlando S, Gallastegui E, Saiz C, Besson A, Pujol MJ, López-Bigas N, Paramio JM, Bigas A, Bachs O.

Oncogene. 2012 Sep 20;31(38):4207-20. doi: 10.1038/onc.2011.582. Epub 2011 Dec 19.

PMID:
22179826
[PubMed - indexed for MEDLINE]
16.

The thyroid hormone receptors modulate the skin response to retinoids.

García-Serrano L, Gomez-Ferrería MA, Contreras-Jurado C, Segrelles C, Paramio JM, Aranda A.

PLoS One. 2011;6(8):e23825. doi: 10.1371/journal.pone.0023825. Epub 2011 Aug 17.

PMID:
21858227
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The thyroid hormone receptors as modulators of skin proliferation and inflammation.

Contreras-Jurado C, García-Serrano L, Gómez-Ferrería M, Costa C, Paramio JM, Aranda A.

J Biol Chem. 2011 Jul 8;286(27):24079-88. doi: 10.1074/jbc.M111.218487. Epub 2011 May 12.

PMID:
21566120
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Establishment of a murine epidermal cell line suitable for in vitro and in vivo skin modelling.

Segrelles C, Holguín A, Hernández P, Ariza JM, Paramio JM, Lorz C.

BMC Dermatol. 2011 Apr 21;11:9. doi: 10.1186/1471-5945-11-9.

PMID:
21510892
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Gene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy.

García-Escudero R, Martínez-Cruz AB, Santos M, Lorz C, Segrelles C, Garaulet G, Saiz-Ladera C, Costa C, Buitrago-Pérez A, Dueñas M, Paramio JM.

Mol Cancer. 2010 Jul 14;9:193. doi: 10.1186/1476-4598-9-193.

PMID:
20630075
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A functional role of RB-dependent pathway in the control of quiescence in adult epidermal stem cells revealed by genomic profiling.

Lorz C, García-Escudero R, Segrelles C, Garín MI, Ariza JM, Santos M, Ruiz S, Lara MF, Martínez-Cruz AB, Costa C, Buitrago-Pérez A, Saiz-Ladera C, Dueñas M, Paramio JM.

Stem Cell Rev. 2010 Jun;6(2):162-77. doi: 10.1007/s12015-010-9139-0.

PMID:
20376578
[PubMed - indexed for MEDLINE]
Free PMC Article

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