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Results: 1 to 20 of 82

1.

The downregulation of ΔNp63 in p53-deficient mouse epidermal tumors favors metastatic behavior.

Bornachea O, López-Calderón FF, Dueñas M, Segrelles C, Lorz C, Suárez-Cabrera C, Marañón M, Paradela-Dobarro B, Santos M, Paramio JM.

Oncotarget. 2015 Jul 1. [Epub ahead of print]

2.

Combined deletion of p38γ and p38δ reduces skin inflammation and protects from carcinogenesis.

Zur R, Garcia-Ibanez L, Nunez-Buiza A, Aparicio N, Liappas G, Escós A, Risco A, Page A, Saiz-Ladera C, Alsina-Beauchamp D, Montans J, Paramio JM, Cuenda A.

Oncotarget. 2015 May 30;6(15):12920-35.

3.

The pluripotency factor NANOG promotes the formation of squamous cell carcinomas.

Palla AR, Piazzolla D, Alcazar N, Cañamero M, Graña O, Gómez-López G, Dominguez O, Dueñas M, Paramio JM, Serrano M.

Sci Rep. 2015 May 19;5:10205. doi: 10.1038/srep10205.

4.

Thyroid hormone signaling controls hair follicle stem cell function.

Contreras-Jurado C, Lorz C, García-Serrano L, Paramio JM, Aranda A.

Mol Biol Cell. 2015 Apr 1;26(7):1263-72. doi: 10.1091/mbc.E14-07-1251. Epub 2015 Feb 5.

5.

NOTCH pathway inactivation promotes bladder cancer progression.

Maraver A, Fernandez-Marcos PJ, Cash TP, Mendez-Pertuz M, Dueñas M, Maietta P, Martinelli P, Muñoz-Martin M, Martínez-Fernández M, Cañamero M, Roncador G, Martinez-Torrecuadrada JL, Grivas D, de la Pompa JL, Valencia A, Paramio JM, Real FX, Serrano M.

J Clin Invest. 2015 Feb;125(2):824-30. doi: 10.1172/JCI78185. Epub 2015 Jan 9.

6.

The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.

Carnero A, Paramio JM.

Front Oncol. 2014 Sep 23;4:252. doi: 10.3389/fonc.2014.00252. eCollection 2014. Review.

7.

Impaired hair growth and wound healing in mice lacking thyroid hormone receptors.

Contreras-Jurado C, García-Serrano L, Martínez-Fernández M, Ruiz-Llorente L, Paramio JM, Aranda A.

PLoS One. 2014 Sep 25;9(9):e108137. doi: 10.1371/journal.pone.0108137. eCollection 2014.

8.

In vivo disruption of an Rb-E2F-Ezh2 signaling loop causes bladder cancer.

Santos M, Martínez-Fernández M, Dueñas M, García-Escudero R, Alfaya B, Villacampa F, Saiz-Ladera C, Costa C, Oteo M, Duarte J, Martínez V, Gómez-Rodriguez MJ, Martín ML, Fernández M, Viatour P, Morcillo MA, Sage J, Castellano D, Rodriguez-Peralto JL, de la Rosa F, Paramio JM.

Cancer Res. 2014 Nov 15;74(22):6565-77. doi: 10.1158/0008-5472.CAN-14-1218. Epub 2014 Sep 24.

PMID:
25252918
9.

Akt signaling leads to stem cell activation and promotes tumor development in epidermis.

Segrelles C, García-Escudero R, Garín MI, Aranda JF, Hernández P, Ariza JM, Santos M, Paramio JM, Lorz C.

Stem Cells. 2014 Jul;32(7):1917-28. doi: 10.1002/stem.1669.

10.

Skin Tumors Rb(eing) Uncovered.

Costa C, Paramio JM, Santos M.

Front Oncol. 2013 Dec 17;3:307. doi: 10.3389/fonc.2013.00307. Review.

11.

PIK3CA gene alterations in bladder cancer are frequent and associate with reduced recurrence in non-muscle invasive tumors.

Dueñas M, Martínez-Fernández M, García-Escudero R, Villacampa F, Marqués M, Saiz-Ladera C, Duarte J, Martínez V, Gómez MJ, Martín ML, Fernández M, Castellano D, Real FX, Rodriguez-Peralto JL, De La Rosa F, Paramio JM.

Mol Carcinog. 2015 Jul;54(7):566-76. doi: 10.1002/mc.22125. Epub 2013 Dec 18.

PMID:
24347284
12.

p21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia.

Saiz-Ladera C, Lara MF, Garín M, Ruiz S, Santos M, Lorz C, García-Escudero R, Martínez-Fernández M, Bravo A, Fernández-Capetillo O, Segrelles C, Paramio JM.

Oncogene. 2014 Sep 11;33(37):4599-612. doi: 10.1038/onc.2013.417. Epub 2013 Oct 14.

PMID:
24121270
13.

The Rho exchange factors Vav2 and Vav3 favor skin tumor initiation and promotion by engaging extracellular signaling loops.

Menacho-Márquez M, García-Escudero R, Ojeda V, Abad A, Delgado P, Costa C, Ruiz S, Alarcón B, Paramio JM, Bustelo XR.

PLoS Biol. 2013 Jul;11(7):e1001615. doi: 10.1371/journal.pbio.1001615. Epub 2013 Jul 23.

14.

A novel tumor suppressor network in squamous malignancies.

Costa C, Santos M, Segrelles C, Dueñas M, Lara MF, Agirre X, Prosper F, García-Escudero R, Paramio JM.

Sci Rep. 2012;2:828. doi: 10.1038/srep00828. Epub 2012 Nov 9.

15.

The rho exchange factors vav2 and vav3 control a lung metastasis-specific transcriptional program in breast cancer cells.

Citterio C, Menacho-Márquez M, García-Escudero R, Larive RM, Barreiro O, Sánchez-Madrid F, Paramio JM, Bustelo XR.

Sci Signal. 2012 Oct 2;5(244):ra71. doi: 10.1126/scisignal.2002962.

16.

Progeny of Lgr5-expressing hair follicle stem cell contributes to papillomavirus-induced tumor development in epidermis.

da Silva-Diz V, Solé-Sánchez S, Valdés-Gutiérrez A, Urpí M, Riba-Artés D, Penin RM, Pascual G, González-Suárez E, Casanovas O, Viñals F, Paramio JM, Batlle E, Muñoz P.

Oncogene. 2013 Aug 8;32(32):3732-43. doi: 10.1038/onc.2012.375. Epub 2012 Sep 3.

PMID:
22945646
17.

A humanized mouse model of HPV-associated pathology driven by E7 expression.

Buitrago-Pérez Á, Hachimi M, Dueñas M, Lloveras B, Santos A, Holguín A, Duarte B, Santiago JL, Akgül B, Rodríguez-Peralto JL, Storey A, Ribas C, Larcher F, del Rio M, Paramio JM, García-Escudero R.

PLoS One. 2012;7(7):e41743. doi: 10.1371/journal.pone.0041743. Epub 2012 Jul 23.

18.

E2F1 loss induces spontaneous tumour development in Rb-deficient epidermis.

Costa C, Santos M, Martínez-Fernández M, Dueñas M, Lorz C, García-Escudero R, Paramio JM.

Oncogene. 2013 Jun 13;32(24):2937-51. doi: 10.1038/onc.2012.316. Epub 2012 Aug 13.

PMID:
22890321
19.

Mouse p53-deficient cancer models as platforms for obtaining genomic predictors of human cancer clinical outcomes.

Dueñas M, Santos M, Aranda JF, Bielza C, Martínez-Cruz AB, Lorz C, Taron M, Ciruelos EM, Rodríguez-Peralto JL, Martín M, Larrañaga P, Dahabreh J, Stathopoulos GP, Rosell R, Paramio JM, García-Escudero R.

PLoS One. 2012;7(8):e42494. doi: 10.1371/journal.pone.0042494. Epub 2012 Aug 7.

20.

The orphan receptor GPR55 drives skin carcinogenesis and is upregulated in human squamous cell carcinomas.

Pérez-Gómez E, Andradas C, Flores JM, Quintanilla M, Paramio JM, Guzmán M, Sánchez C.

Oncogene. 2013 May 16;32(20):2534-42. doi: 10.1038/onc.2012.278. Epub 2012 Jul 2.

PMID:
22751111
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