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Items: 1 to 20 of 59


Factor-inhibiting HIF-1 (FIH-1) is required for human vascular endothelial cell survival.

Kiriakidis S, Henze AT, Kruszynska-Ziaja I, Skobridis K, Theodorou V, Paleolog EM, Mazzone M.

FASEB J. 2015 Jul;29(7):2814-27. doi: 10.1096/fj.14-252379. Epub 2015 Apr 2.


Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer.

Khong TL, Thairu N, Larsen H, Dawson PM, Kiriakidis S, Paleolog EM.

BMC Cancer. 2013 Nov 2;13:518. doi: 10.1186/1471-2407-13-518.


Hypoxia-inducible factor pathway and diseases of the vascular wall.

Lim CS, Kiriakidis S, Sandison A, Paleolog EM, Davies AH.

J Vasc Surg. 2013 Jul;58(1):219-30. doi: 10.1016/j.jvs.2013.02.240. Epub 2013 Apr 30. Review.


Cell death pattern of a varicose vein organ culture model.

Lim CS, Kiriakidis S, Paleolog EM, Davies AH.

Vascular. 2013 Jun;21(3):129-36.


Vascular endothelium--role in chronic inflammatory disease.

Kiriakidis S, Paleolog EM.

Postepy Biochem. 2013;59(4):415-23. Review.


Differential effects of Th1 versus Th2 cytokines in combination with hypoxia on HIFs and angiogenesis in RA.

Larsen H, Muz B, Khong TL, Feldmann M, Paleolog EM.

Arthritis Res Ther. 2012 Aug 6;14(4):R180. doi: 10.1186/ar3934.


Gene expression profiling and functional analysis of angiogenic markers in murine collagen-induced arthritis.

Raatz Y, Ibrahim S, Feldmann M, Paleolog EM.

Arthritis Res Ther. 2012 Jul 20;14(4):R169. doi: 10.1186/ar3922.


The effects of doxycycline and micronized purified flavonoid fraction on human vein wall remodeling are not hypoxia-inducible factor pathway-dependent.

Lim CS, Kiriakidis S, Paleolog EM, Davies AH.

J Vasc Surg. 2012 Oct;56(4):1069-77. doi: 10.1016/j.jvs.2012.02.067. Epub 2012 Jun 6.


Prolyl hydroxylase domain enzyme 2 is the major player in regulating hypoxic responses in rheumatoid arthritis.

Muz B, Larsen H, Madden L, Kiriakidis S, Paleolog EM.

Arthritis Rheum. 2012 Sep;64(9):2856-67. doi: 10.1002/art.34479.


Hypoxia--a key regulator of angiogenesis and inflammation in rheumatoid arthritis.

Konisti S, Kiriakidis S, Paleolog EM.

Nat Rev Rheumatol. 2012 Jan 31;8(3):153-62. doi: 10.1038/nrrheum.2011.205. Review.


Increased activation of the hypoxia-inducible factor pathway in varicose veins.

Lim CS, Kiriakidis S, Paleolog EM, Davies AH.

J Vasc Surg. 2012 May;55(5):1427-39. doi: 10.1016/j.jvs.2011.10.111. Epub 2012 Jan 24.


Human epidermal growth factor receptor bispecific ligand trap RB200: abrogation of collagen-induced arthritis in combination with tumour necrosis factor blockade.

Gompels LL, Malik NM, Madden L, Jin P, Feldmann M, Shepard HM, Paleolog EM.

Arthritis Res Ther. 2011;13(5):R161. doi: 10.1186/ar3480. Epub 2011 Oct 7.


Muscle hypoxia in rheumatoid hands: does it play a role in ulnar drift?

Akhavani MA, Paleolog EM, Kang N.

J Hand Surg Am. 2011 Apr;36(4):677-85. doi: 10.1016/j.jhsa.2011.01.035.


A window on disease pathogenesis and potential therapeutic strategies: molecular imaging for arthritis.

Gompels LL, Paleolog EM.

Arthritis Res Ther. 2011 Jan 31;13(1):201. doi: 10.1186/ar3197. Review.


Kynurenine metabolism in health and disease.

Kolodziej LR, Paleolog EM, Williams RO.

Amino Acids. 2011 Nov;41(5):1173-83. doi: 10.1007/s00726-010-0787-9. Epub 2010 Oct 23. Review.


The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells.

Sperone A, Dryden NH, Birdsey GM, Madden L, Johns M, Evans PC, Mason JC, Haskard DO, Boyle JJ, Paleolog EM, Randi AM.

Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):142-50. doi: 10.1161/ATVBAHA.110.216473. Epub 2010 Oct 21.


In vivo fluorescence imaging of E-selectin: quantitative detection of endothelial activation in a mouse model of arthritis.

Gompels LL, Madden L, Lim NH, Inglis JJ, McConnell E, Vincent TL, Haskard DO, Paleolog EM.

Arthritis Rheum. 2011 Jan;63(1):107-17. doi: 10.1002/art.30082.


Inhibitory effect of TIMP influences the morphology of varicose veins.

Aravind B, Saunders B, Navin T, Sandison A, Monaco C, Paleolog EM, Davies AH.

Eur J Vasc Endovasc Surg. 2010 Dec;40(6):754-65. doi: 10.1016/j.ejvs.2010.04.028. Epub 2010 Jul 3.


Regulation of the angiopoietin-Tie ligand-receptor system with a novel splice variant of Tie1 reduces the severity of murine arthritis.

Malik NM, Jin P, Raatz Y, Sumariwalla PF, Kiriakidis S, Shepard M, Feldmann M, Paleolog EM.

Rheumatology (Oxford). 2010 Oct;49(10):1828-39. doi: 10.1093/rheumatology/keq163. Epub 2010 Jun 14.


In vitro target validation and in vivo efficacy of p38 MAP kinase inhibition in established chronic collagen-induced arthritis model: a pre-clinical study.

Triantaphyllopoulos K, Madden L, Rioja I, Essex D, Buckton J, Malhotra R, Ray K, Binks M, Paleolog EM.

Clin Exp Rheumatol. 2010 Mar-Apr;28(2):176-85. Epub 2010 May 13.

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