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Items: 1 to 20 of 194


Yeast as a tool to select inhibitors of the cullin deneddylating enzyme Csn5.

Cirigliano A, Stirpe A, Menta S, Mori M, Dell'Edera D, Pick E, Negri R, Botta B, Rinaldi T.

J Enzyme Inhib Med Chem. 2016 Mar 30:1-6. [Epub ahead of print]


Absolute and Relative Activity Values in Assessing the Effect of NADPH Oxidase Inhibitors.

Pick E.

Antioxid Redox Signal. 2015 Nov 20;23(15):1250-1. doi: 10.1089/ars.2015.6470.


Aeromonas chitinase degrades chironomid egg masses.

Laviad S, Golan A, Shaked T, Vaizel-Ohayon D, Halpern M, Pick E.

Environ Microbiol Rep. 2016 Feb;8(1):30-7. doi: 10.1111/1758-2229.12347. Epub 2015 Dec 21.


Base-CP proteasome can serve as a platform for stepwise lid formation.

Yu Z, Livnat-Levanon N, Kleifeld O, Mansour W, Nakasone MA, Castaneda CA, Dixon EK, Fushman D, Reis N, Pick E, Glickman MH.

Biosci Rep. 2015 Jan 27;35(3). pii: e00194. doi: 10.1042/BSR20140173.


A Cys-Gly-Cys triad in the dehydrogenase region of Nox2 plays a key role in the interaction with p67phox.

Dahan I, Smith SM, Pick E.

J Leukoc Biol. 2015 Nov;98(5):859-74. doi: 10.1189/jlb.4A0315-107R. Epub 2015 Jul 9.


Two CGD Families with a Hypomorphic Mutation in the Activation Domain of p67phox.

Roos D, van Buul JD, Tool AT, Matute JD, Marchal CM, Hayee B, Köker MY, de Boer M, van Leeuwen K, Segal AW, Pick E, Dinauer MC.

J Clin Cell Immunol. 2014 Jun 30;5(3). pii: 1000231.


The dehydrogenase region of the NADPH oxidase component Nox2 acts as a protein disulfide isomerase (PDI) resembling PDIA3 with a role in the binding of the activator protein p67 (phox.).

Bechor E, Dahan I, Fradin T, Berdichevsky Y, Zahavi A, Federman Gross A, Rafalowski M, Pick E.

Front Chem. 2015 Feb 4;3:3. doi: 10.3389/fchem.2015.00003. eCollection 2015.


Base-CP proteasome can serve as a platform for stepwise lid formation.

Yu Z, Livnat-Levanon N, Kleifeld O, Mansour W, Nakasone MA, Castaneda CA, Dixon EK, Fushman D, Reis N, Pick E, Glickman MH.

Biosci Rep. 2015 Jan 27. [Epub ahead of print]


Moonlighting and pleiotropy within two regulators of the degradation machinery: the proteasome lid and the CSN.

Pick E, Bramasole L.

Biochem Soc Trans. 2014 Dec;42(6):1786-91. doi: 10.1042/BST20140227. Review.


Cullin E3 ligases and their rewiring by viral factors.

Mahon C, Krogan NJ, Craik CS, Pick E.

Biomolecules. 2014 Oct 13;4(4):897-930. doi: 10.3390/biom4040897. Review.


Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key task.

Pick E.

Small GTPases. 2014;5:e27952. doi: 10.4161/sgtp.27952. Epub 2014 Mar 5. Review.


Targeted degradation of abscisic acid receptors is mediated by the ubiquitin ligase substrate adaptor DDA1 in Arabidopsis.

Irigoyen ML, Iniesto E, Rodriguez L, Puga MI, Yanagawa Y, Pick E, Strickland E, Paz-Ares J, Wei N, De Jaeger G, Rodriguez PL, Deng XW, Rubio V.

Plant Cell. 2014 Feb;26(2):712-28. doi: 10.1105/tpc.113.122234. Epub 2014 Feb 21.


Cell-free NADPH oxidase activation assays: "in vitro veritas".

Pick E.

Methods Mol Biol. 2014;1124:339-403. doi: 10.1007/978-1-62703-845-4_22.


The COP9 signalosome is involved in the regulation of lipid metabolism and of transition metals uptake in Saccharomyces cerevisiae.

Licursi V, Salvi C, De Cesare V, Rinaldi T, Mattei B, Fabbri C, Serino G, Bramasole L, Zimbler JZ, Pick E, Barnes BM, Bard M, Negri R.

FEBS J. 2014 Jan;281(1):175-90. doi: 10.1111/febs.12584. Epub 2013 Nov 25.


COP9 signalosome subunit Csn8 is involved in maintaining proper duration of the G1 phase.

Liu C, Guo LQ, Menon S, Jin D, Pick E, Wang X, Deng XW, Wei N.

J Biol Chem. 2013 Jul 12;288(28):20443-52. doi: 10.1074/jbc.M113.468959. Epub 2013 May 20.


Duplication and familial promiscuity within the proteasome lid and COP9 signalosome kin complexes.

Serino G, Pick E.

Plant Sci. 2013 Apr;203-204:89-97. doi: 10.1016/j.plantsci.2012.12.018. Epub 2013 Jan 5. Review.


Formation of alternative proteasomes: same lady, different cap?

Pick E, Berman TS.

FEBS Lett. 2013 Mar 1;587(5):389-93. doi: 10.1016/j.febslet.2013.01.014. Epub 2013 Jan 17.


The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain.

Pick E, Golan A, Zimbler JZ, Guo L, Sharaby Y, Tsuge T, Hofmann K, Wei N.

PLoS One. 2012;7(8):e43980. doi: 10.1371/journal.pone.0043980. Epub 2012 Aug 30.


Strategies for identifying synthetic peptides to act as inhibitors of NADPH oxidases, or "all that you did and did not want to know about Nox inhibitory peptides".

Dahan I, Pick E.

Cell Mol Life Sci. 2012 Jul;69(14):2283-305. doi: 10.1007/s00018-012-1007-4. Epub 2012 May 6. Review.


Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation.

Bosco EE, Kumar S, Marchioni F, Biesiada J, Kordos M, Szczur K, Meller J, Seibel W, Mizrahi A, Pick E, Filippi MD, Zheng Y.

Chem Biol. 2012 Feb 24;19(2):228-42. doi: 10.1016/j.chembiol.2011.12.017.

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