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Results: 1 to 20 of 334

1.

Prolonged and tunable residence time using reversible covalent kinase inhibitors.

Bradshaw JM, McFarland JM, Paavilainen VO, Bisconte A, Tam D, Phan VT, Romanov S, Finkle D, Shu J, Patel V, Ton T, Li X, Loughhead DG, Nunn PA, Karr DE, Gerritsen ME, Funk JO, Owens TD, Verner E, Brameld KA, Hill RJ, Goldstein DM, Taunton J.

Nat Chem Biol. 2015 Jul;11(7):525-31. doi: 10.1038/nchembio.1817. Epub 2015 May 25.

PMID:
26006010
2.

Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis.

Khorooshi R, Mørch MT, Holm TH, Berg CT, Dieu RT, Dræby D, Issazadeh-Navikas S, Weiss S, Lienenklaus S, Owens T.

Acta Neuropathol. 2015 Jul;130(1):107-18. doi: 10.1007/s00401-015-1418-z. Epub 2015 Apr 14.

3.

Targeting interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) using a novel covalent inhibitor PRN694.

Zhong Y, Dong S, Strattan E, Ren L, Butchar JP, Thornton K, Mishra A, Porcu P, Bradshaw JM, Bisconte A, Owens TD, Verner E, Brameld KA, Funk JO, Hill RJ, Johnson AJ, Dubovsky JA.

J Biol Chem. 2015 Mar 6;290(10):5960-78. doi: 10.1074/jbc.M114.614891. Epub 2015 Jan 15.

PMID:
25593320
4.

Standardized patient assessment of medical student empathy: ethnicity and gender effects in a multi-institutional study.

Berg K, Blatt B, Lopreiato J, Jung J, Schaeffer A, Heil D, Owens T, Carter-Nolan PL, Berg D, Veloski J, Darby E, Hojat M.

Acad Med. 2015 Jan;90(1):105-11. doi: 10.1097/ACM.0000000000000529.

PMID:
25558813
5.

Finding the perfect spot for fluorine: improving potency up to 40-fold during a rational fluorine scan of a Bruton's Tyrosine Kinase (BTK) inhibitor scaffold.

Lou Y, Sweeney ZK, Kuglstatter A, Davis D, Goldstein DM, Han X, Hong J, Kocer B, Kondru RK, Litman R, McIntosh J, Sarma K, Suh J, Taygerly J, Owens TD.

Bioorg Med Chem Lett. 2015 Jan 15;25(2):367-71. doi: 10.1016/j.bmcl.2014.11.030. Epub 2014 Nov 20.

PMID:
25466710
6.

Clinical and immunologic assessment of a cluster method during allergen immunotherapy refill dosing.

Waibel KH, Owens TJ, Crisp HC, Gomez RA.

J Allergy Clin Immunol Pract. 2014 Nov-Dec;2(6):793-4. doi: 10.1016/j.jaip.2014.09.003. Epub 2014 Oct 3. No abstract available.

PMID:
25439374
7.

Nutritional management of idiopathic epilepsy in dogs.

Larsen JA, Owens TJ, Fascetti AJ.

J Am Vet Med Assoc. 2014 Sep 1;245(5):504-8. doi: 10.2460/javma.245.5.504. No abstract available.

PMID:
25148091
8.

Thymic CCL2 influences induction of T-cell tolerance.

Cédile O, Løbner M, Toft-Hansen H, Frank I, Wlodarczyk A, Irla M, Owens T.

J Autoimmun. 2014 Dec;55:73-85. doi: 10.1016/j.jaut.2014.07.004. Epub 2014 Aug 14.

PMID:
25129504
9.

Giant, completely calcified lumbar juxtafacet cyst: report of an unusual case.

Huang KT, Owens TR, Wang TS, Moreno JR, Bagley JH, Bagley CA.

Global Spine J. 2014 Aug;4(3):175-8. doi: 10.1055/s-0033-1363591. Epub 2013 Dec 19.

10.

Chemokine receptor expression by inflammatory T cells in EAE.

Mony JT, Khorooshi R, Owens T.

Front Cell Neurosci. 2014 Jul 4;8:187. doi: 10.3389/fncel.2014.00187. eCollection 2014.

11.

Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer.

Owens TW, Rogers RL, Best SA, Ledger A, Mooney AM, Ferguson A, Shore P, Swarbrick A, Ormandy CJ, Simpson PT, Carroll JS, Visvader JE, Naylor MJ.

Cancer Res. 2014 Sep 15;74(18):5277-86. doi: 10.1158/0008-5472.CAN-14-0053. Epub 2014 Jul 23.

12.

Dialectical behaviour therapy-informed skills training for deliberate self-harm: a controlled trial with 3-month follow-up data.

Gibson J, Booth R, Davenport J, Keogh K, Owens T.

Behav Res Ther. 2014 Sep;60:8-14. doi: 10.1016/j.brat.2014.06.007. Epub 2014 Jul 2.

PMID:
25036538
13.

The complex immunology of multiple sclerosis.

Owens T.

Mult Scler. 2014 Jun 16;20(8):1023-1024. [Epub ahead of print] No abstract available.

PMID:
24948791
14.

Total dietary fiber composition of diets used for management of obesity and diabetes mellitus in cats.

Owens TJ, Larsen JA, Farcas AK, Nelson RW, Kass PH, Fascetti AJ.

J Am Vet Med Assoc. 2014 Jul 1;245(1):99-105. doi: 10.2460/javma.245.1.99.

PMID:
24941393
15.

Clinical question: are non-steroidal anti-inflammatories superior to acetaminophen for sprains/strains?

Wheeler H, Vonfeldt K, Kavanaugh A, Owens T.

J Okla State Med Assoc. 2014 Mar;107(3):109-10. Review. No abstract available.

PMID:
24800464
16.

Phosphorylation of the proapoptotic BH3-only protein bid primes mitochondria for apoptosis during mitotic arrest.

Wang P, Lindsay J, Owens TW, Mularczyk EJ, Warwood S, Foster F, Streuli CH, Brennan K, Gilmore AP.

Cell Rep. 2014 May 8;7(3):661-71. doi: 10.1016/j.celrep.2014.03.050. Epub 2014 Apr 24.

17.

Structure-based drug design of RN486, a potent and selective Bruton's tyrosine kinase (BTK) inhibitor, for the treatment of rheumatoid arthritis.

Lou Y, Han X, Kuglstatter A, Kondru RK, Sweeney ZK, Soth M, McIntosh J, Litman R, Suh J, Kocer B, Davis D, Park J, Frauchiger S, Dewdney N, Zecic H, Taygerly JP, Sarma K, Hong J, Hill RJ, Gabriel T, Goldstein DM, Owens TD.

J Med Chem. 2015 Jan 8;58(1):512-6. doi: 10.1021/jm500305p. Epub 2014 Apr 16.

PMID:
24712864
18.

Comparison of microglia and infiltrating CD11c⁺ cells as antigen presenting cells for T cell proliferation and cytokine response.

Wlodarczyk A, Løbner M, Cédile O, Owens T.

J Neuroinflammation. 2014 Mar 25;11:57. doi: 10.1186/1742-2094-11-57.

19.

What is microglia neurotoxicity (Not)?

Biber K, Owens T, Boddeke E.

Glia. 2014 Jun;62(6):841-54. doi: 10.1002/glia.22654. Epub 2014 Mar 3. Review.

PMID:
24590682
20.

Interferons in the central nervous system: a few instruments play many tunes.

Owens T, Khorooshi R, Wlodarczyk A, Asgari N.

Glia. 2014 Mar;62(3):339-55. Review.

PMID:
24588027
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