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Results: 1 to 20 of 691

1.

De novo CNVs in Bipolar Affective Disorder and Schizophrenia.

Georgieva L, Rees E, Moran JL, Chambert KD, Milanova V, Craddock N, Purcell S, Sklar P, McCarroll S, Holmans P, O'Donovan MC, Owen MJ, Kirov G.

Hum Mol Genet. 2014 Jul 23. pii: ddu379. [Epub ahead of print]

PMID:
25055870
[PubMed - as supplied by publisher]
2.

Authors' reply.

Rees E, Walters JT, Owen MJ, Kirov G.

Br J Psychiatry. 2014 Jul;205(1):78. doi: 10.1192/bjp.205.1.78. No abstract available.

PMID:
24986392
[PubMed - in process]
3.

Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: A genome-wide association and polygenic scoring study.

Mullins N, Perroud N, Uher R, Butler AW, Cohen-Woods S, Rivera M, Malki K, Euesden J, Power RA, Tansey KE, Jones L, Jones I, Craddock N, Owen MJ, Korszun A, Gill M, Mors O, Preisig M, Maier W, Rietschel M, Rice JP, Müller-Myhsok B, Binder EB, Lucae S, Ising M, Craig IW, Farmer AE, McGuffin P, Breen G, Lewis CM.

Am J Med Genet B Neuropsychiatr Genet. 2014 Jul;165(5):428-37. doi: 10.1002/ajmg.b.32247. Epub 2014 Jun 25.

PMID:
24964207
[PubMed - in process]
4.

Biological overlap of attention-deficit/hyperactivity disorder and autism spectrum disorder: evidence from copy number variants.

Martin J, Cooper M, Hamshere ML, Pocklington A, Scherer SW, Kent L, Gill M, Owen MJ, Williams N, O'Donovan MC, Thapar A, Holmans P.

J Am Acad Child Adolesc Psychiatry. 2014 Jul;53(7):761-770.e26. doi: 10.1016/j.jaac.2014.03.004. Epub 2014 Apr 21.

PMID:
24954825
[PubMed - in process]
Free PMC Article
5.

Genomic insights into the overlap between psychiatric disorders: implications for research and clinical practice.

Doherty JL, Owen MJ.

Genome Med. 2014 Apr 28;6(4):29. doi: 10.1186/gm546. eCollection 2014. Review.

PMID:
24944580
[PubMed]
Free PMC Article
6.

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Denning N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Schmidt H, Kunkle B, Dunstan ML, Vronskaya M; United Kingdom Brain Expression Consortium, Johnson AD, Ruiz A, Bihoreau MT, Reitz C, Pasquier F, Hollingworth P, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Hernández I, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, George-Hyslop PS, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Garcia FS, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Scarpini E, Bonuccelli U, Mancuso M, Siciliano G, Moebus S, Mecocci P, Zompo MD, Maier W, Hampel H, Pilotto A, Frank-García A, Panza F, Solfrizzi V, Caffarra P, Nacmias B, Perry W, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Haines JL, Lathrop M, Pericak-Vance MA, Launer LJ, Van Broeckhoven C, Farrer LA, van Duijn CM, Ramirez A, Seshadri S, Schellenberg GD, Amouyel P, Williams J.

PLoS One. 2014 Jun 12;9(6):e94661. doi: 10.1371/journal.pone.0094661. eCollection 2014.

PMID:
24922517
[PubMed - in process]
Free PMC Article
7.

Exploring the indirect effects of catechol-O-methyltransferase (COMT) genotype on psychotic experiences through cognitive function and anxiety disorders in a large birth cohort of children.

Niarchou M, Zammit S, Escott-Price V, Owen MJ, van den Bree MB.

Am J Med Genet B Neuropsychiatr Genet. 2014 Jul;165(5):410-20. doi: 10.1002/ajmg.b.32245. Epub 2014 May 27.

PMID:
24862404
[PubMed - in process]
8.

Relationship between obesity and the risk of clinically significant depression: Mendelian randomisation study.

Hung CF, Rivera M, Craddock N, Owen MJ, Gill M, Korszun A, Maier W, Mors O, Preisig M, Rice JP, Rietschel M, Jones L, Middleton L, Aitchison KJ, Davis OS, Breen G, Lewis C, Farmer A, McGuffin P.

Br J Psychiatry. 2014 Jul;205(1):24-8. doi: 10.1192/bjp.bp.113.130419. Epub 2014 May 8.

PMID:
24809401
[PubMed - in process]
Free PMC Article
9.

Copy number variation in schizophrenia in Sweden.

Szatkiewicz JP, O'Dushlaine C, Chen G, Chambert K, Moran JL, Neale BM, Fromer M, Ruderfer D, Akterin S, Bergen SE, Kähler A, Magnusson PK, Kim Y, Crowley JJ, Rees E, Kirov G, O'Donovan MC, Owen MJ, Walters J, Scolnick E, Sklar P, Purcell S, Hultman CM, McCarroll SA, Sullivan PF.

Mol Psychiatry. 2014 Jul;19(7):762-73. doi: 10.1038/mp.2014.40. Epub 2014 Apr 29.

PMID:
24776740
[PubMed - in process]
10.

The synapse in schizophrenia.

Pocklington AJ, O'Donovan M, Owen MJ.

Eur J Neurosci. 2014 Apr;39(7):1059-67. doi: 10.1111/ejn.12489.

PMID:
24712986
[PubMed - in process]
11.

Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery.

Lee EC, Liang Q, Ali H, Bayliss L, Beasley A, Bloomfield-Gerdes T, Bonoli L, Brown R, Campbell J, Carpenter A, Chalk S, Davis A, England N, Fane-Dremucheva A, Franz B, Germaschewski V, Holmes H, Holmes S, Kirby I, Kosmac M, Legent A, Lui H, Manin A, O'Leary S, Paterson J, Sciarrillo R, Speak A, Spensberger D, Tuffery L, Waddell N, Wang W, Wells S, Wong V, Wood A, Owen MJ, Friedrich GA, Bradley A.

Nat Biotechnol. 2014 Apr;32(4):356-63. doi: 10.1038/nbt.2825. Epub 2014 Mar 16.

PMID:
24633243
[PubMed - in process]
12.

The Research Domain Criteria: moving the goalposts to change the game.

Doherty JL, Owen MJ.

Br J Psychiatry. 2014 Mar;204(3):171-3. doi: 10.1192/bjp.bp.113.133330.

PMID:
24590970
[PubMed - in process]
13.

Genetic relationships between schizophrenia, bipolar disorder, and schizoaffective disorder.

Cardno AG, Owen MJ.

Schizophr Bull. 2014 May;40(3):504-15. doi: 10.1093/schbul/sbu016. Epub 2014 Feb 24.

PMID:
24567502
[PubMed - in process]
14.

Further evidence for high rates of schizophrenia in 22q11.2 deletion syndrome.

Monks S, Niarchou M, Davies AR, Walters JT, Williams N, Owen MJ, van den Bree MB, Murphy KC.

Schizophr Res. 2014 Mar;153(1-3):231-6. doi: 10.1016/j.schres.2014.01.020. Epub 2014 Feb 15.

PMID:
24534796
[PubMed - in process]
15.

De novo mutations in schizophrenia implicate synaptic networks.

Fromer M, Pocklington AJ, Kavanagh DH, Williams HJ, Dwyer S, Gormley P, Georgieva L, Rees E, Palta P, Ruderfer DM, Carrera N, Humphreys I, Johnson JS, Roussos P, Barker DD, Banks E, Milanova V, Grant SG, Hannon E, Rose SA, Chambert K, Mahajan M, Scolnick EM, Moran JL, Kirov G, Palotie A, McCarroll SA, Holmans P, Sklar P, Owen MJ, Purcell SM, O'Donovan MC.

Nature. 2014 Feb 13;506(7487):179-84. doi: 10.1038/nature12929. Epub 2014 Jan 22.

PMID:
24463507
[PubMed - indexed for MEDLINE]
16.

Analysis of copy number variations at 15 schizophrenia-associated loci.

Rees E, Walters JT, Georgieva L, Isles AR, Chambert KD, Richards AL, Mahoney-Davies G, Legge SE, Moran JL, McCarroll SA, O'Donovan MC, Owen MJ, Kirov G.

Br J Psychiatry. 2014 Feb;204(2):108-14. doi: 10.1192/bjp.bp.113.131052. Epub 2013 Dec 5.

PMID:
24311552
[PubMed - in process]
Free PMC Article
17.

Evidence that duplications of 22q11.2 protect against schizophrenia.

Rees E, Kirov G, Sanders A, Walters JT, Chambert KD, Shi J, Szatkiewicz J, O'Dushlaine C, Richards AL, Green EK, Jones I, Davies G, Legge SE, Moran JL, Pato C, Pato M, Genovese G, Levinson D, Duan J, Moy W, Göring HH, Morris D, Cormican P, Kendler KS, O'Neill FA, Riley B, Gill M, Corvin A; Wellcome Trust Case Control Consortium, Craddock N, Sklar P, Hultman C, Sullivan PF, Gejman PV, McCarroll SA, O'Donovan MC, Owen MJ.

Mol Psychiatry. 2014 Jan;19(1):37-40. doi: 10.1038/mp.2013.156. Epub 2013 Nov 12.

PMID:
24217254
[PubMed - in process]
Free PMC Article
18.

Investigating the genetic variation underlying episodicity in major depressive disorder: suggestive evidence for a bipolar contribution.

Ferentinos P, Rivera M, Ising M, Spain SL, Cohen-Woods S, Butler AW, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, Mors O, Rietschel M, Lucae S, Binder EB, Preisig M, Tozzi F, Muglia P, Breen G, Craig IW, Farmer AE, Müller-Myhsok B, McGuffin P, Lewis CM.

J Affect Disord. 2014 Feb;155:81-9. doi: 10.1016/j.jad.2013.10.027. Epub 2013 Oct 29.

PMID:
24215895
[PubMed - in process]
19.

A Population-Based Study of Genetic Variation and Psychotic Experiences in Adolescents.

Zammit S, Hamshere M, Dwyer S, Georgiva L, Timpson N, Moskvina V, Richards A, Evans DM, Lewis G, Jones P, Owen MJ, O'Donovan MC.

Schizophr Bull. 2013 Oct 30. [Epub ahead of print]

PMID:
24174267
[PubMed - as supplied by publisher]
Free Article
20.

CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1.

Rees E, Walters JT, Chambert KD, O'Dushlaine C, Szatkiewicz J, Richards AL, Georgieva L, Mahoney-Davies G, Legge SE, Moran JL, Genovese G, Levinson D, Morris DW, Cormican P, Kendler KS, O'Neill FA, Riley B, Gill M, Corvin A; Wellcome Trust Case Control Consortium, Sklar P, Hultman C, Pato C, Pato M, Sullivan PF, Gejman PV, McCarroll SA, O'Donovan MC, Owen MJ, Kirov G.

Hum Mol Genet. 2014 Mar 15;23(6):1669-76. doi: 10.1093/hmg/ddt540. Epub 2013 Oct 26.

PMID:
24163246
[PubMed - in process]
Free PMC Article

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