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Results: 1 to 20 of 716

1.

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.

Lee SH, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AA, Ripke S, Andreassen OA, Frisell T, Gusev A, Hu X, Karlsson R, Mantzioris VX, McGrath JJ, Mehta D, Stahl EA, Zhao Q, Kendler KS, Sullivan PF, Price AL, O'Donovan M, Okada Y, Mowry BJ, Raychaudhuri S, Wray NR; Schizophrenia Working Group of the Psychiatric Genomics Consortium and Rheumatoid Arthritis Consortium International; Schizophrenia Working Group of the Psychiatric Genomics Consortium authors, Byerley W, Cahn W, Cantor RM, Cichon S, Cormican P, Curtis D, Djurovic S, Escott-Price V, Gejman PV, Georgieva L, Giegling I, Hansen TF, Ingason A, Kim Y, Konte B, Lee PH, McIntosh A, McQuillin A, Morris DW, Nöthen MM, O'Dushlaine C, Olincy A, Olsen L, Pato CN, Pato MT, Pickard BS, Posthuma D, Rasmussen HB, Rietschel M, Rujescu D, Schulze TG, Silverman JM, Thirumalai S, Werge T; Schizophrenia Working Group of the Psychiatric Genomics Consortium collaborators, Agartz I, Amin F, Azevedo MH, Bass N, Black DW, Blackwood DH, Bruggeman R, Buccola NG, Choudhury K, Cloninger RC, Corvin A, Craddock N, Daly MJ, Datta S, Donohoe GJ, Duan J, Dudbridge F, Fanous A, Freedman R, Freimer NB, Friedl M, Gill M, Gurling H, De Haan L, Hamshere ML, Hartmann AM, Holmans PA, Kahn RS, Keller MC, Kenny E, Kirov GK, Krabbendam L, Krasucki R, Lawrence J, Lencz T, Levinson DF, Lieberman JA, Lin DY, Linszen DH, Magnusson PK, Maier W, Malhotra AK, Mattheisen M, Mattingsdal M, McCarroll SA, Medeiros H, Melle I, Milanova V, Myin-Germeys I, Neale BM, Ophoff RA, Owen MJ, Pimm J, Purcell SM, Puri V, Quested DJ, Rossin L, Ruderfer D, Sanders AR, Shi J, Sklar P, St Clair D, Scott Stroup T, Van Os J, Visscher PM, Wiersma D, Zammit S; Rheumatoid Arthritis Consortium International authors, Louis Bridges S Jr, Choi HK, Coenen MJ, de Vries N, Dieud P, Greenberg JD, Huizinga TW, Padyukov L, Siminovitch KA, Tak PP, Worthington J; Rheumatoid Arthritis Consortium International collaborators, De Jager PL, Denny JC, Gregersen PK, Klareskog L, Mariette X, Plenge RM, van Laar M, van Riel P.

Int J Epidemiol. 2015 Aug 18. pii: dyv136. [Epub ahead of print]

PMID:
26286434
2.

Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia.

Rees E, Kirov G, Walters JT, Richards AL, Howrigan D, Kavanagh DH, Pocklington AJ, Fromer M, Ruderfer DM, Georgieva L, Carrera N, Gormley P, Palta P, Williams H, Dwyer S, Johnson JS, Roussos P, Barker DD, Banks E, Milanova V, Rose SA, Chambert K, Mahajan M, Scolnick EM, Moran JL, Tsuang MT, Glatt SJ, Chen WJ, Hwu HG; Taiwanese Trios Exome Sequencing Consortium, Neale BM, Palotie A, Sklar P, Purcell SM, McCarroll SA, Holmans P, Owen MJ, O'Donovan MC.

Transl Psychiatry. 2015 Jul 21;5:e607. doi: 10.1038/tp.2015.99.

PMID:
26196440
3.

A national population-based e-cohort of people with psychosis (PsyCymru) linking prospectively ascertained phenotypically rich and genetic data to routinely collected records: Overview, recruitment and linkage.

Lloyd K, McGregor J, John A, Craddock N, Walters JT, Linden D, Jones I, Bentall R, Lyons RA, Ford DV, Owen MJ.

Schizophr Res. 2015 Aug;166(1-3):131-6. doi: 10.1016/j.schres.2015.05.036. Epub 2015 Jun 29.

PMID:
26139629
4.

Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia.

Pocklington AJ, Rees E, Walters JT, Han J, Kavanagh DH, Chambert KD, Holmans P, Moran JL, McCarroll SA, Kirov G, O'Donovan MC, Owen MJ.

Neuron. 2015 Jun 3;86(5):1203-14. doi: 10.1016/j.neuron.2015.04.022.

5.

A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder.

Hung CF, Breen G, Czamara D, Corre T, Wolf C, Kloiber S, Bergmann S, Craddock N, Gill M, Holsboer F, Jones L, Jones I, Korszun A, Kutalik Z, Lucae S, Maier W, Mors O, Owen MJ, Rice J, Rietschel M, Uher R, Vollenweider P, Waeber G, Craig IW, Farmer AE, Lewis CM, Müller-Myhsok B, Preisig M, McGuffin P, Rivera M.

BMC Med. 2015 Apr 17;13:86. doi: 10.1186/s12916-015-0334-3.

6.

Phenotypic Association Analyses with Copy Number Variation in Recurrent Depressive Disorder.

Rucker JJ, Tansey KE, Rivera M, Pinto D, Cohen-Woods S, Uher R, Aitchison KJ, Craddock N, Owen MJ, Jones L, Jones I, Korszun A, Barnes MR, Preisig M, Mors O, Maier W, Rice J, Rietschel M, Holsboer F, Farmer AE, Craig IW, Scherer SW, McGuffin P, Breen G.

Biol Psychiatry. 2015 Feb 25. pii: S0006-3223(15)00150-X. doi: 10.1016/j.biopsych.2015.02.025. [Epub ahead of print]

7.

Schizophrenia risk variants modulate white matter volume across the psychosis spectrum: evidence from two independent cohorts.

Oertel-Knöchel V, Lancaster TM, Knöchel C, Stäblein M, Storchak H, Reinke B, Jurcoane A, Kniep J, Prvulovic D, Mantripragada K, Tansey KE, O'Donovan MC, Owen MJ, Linden DE.

Neuroimage Clin. 2015 Mar 13;7:764-70. doi: 10.1016/j.nicl.2015.03.005. eCollection 2015.

8.

Shared genetic influences between attention-deficit/hyperactivity disorder (ADHD) traits in children and clinical ADHD.

Stergiakouli E, Martin J, Hamshere ML, Langley K, Evans DM, St Pourcain B, Timpson NJ, Owen MJ, O'Donovan M, Thapar A, Davey Smith G.

J Am Acad Child Adolesc Psychiatry. 2015 Apr;54(4):322-7. doi: 10.1016/j.jaac.2015.01.010. Epub 2015 Jan 29.

9.

Evaluating historical candidate genes for schizophrenia.

Farrell MS, Werge T, Sklar P, Owen MJ, Ophoff RA, O'Donovan MC, Corvin A, Cichon S, Sullivan PF.

Mol Psychiatry. 2015 May;20(5):555-62. doi: 10.1038/mp.2015.16. Epub 2015 Mar 10.

PMID:
25754081
10.

Widespread occurrence of both metabolic and target-site herbicide resistance mechanisms in Lolium rigidum populations.

Han H, Yu Q, Owen MJ, Cawthray GR, Powles SB.

Pest Manag Sci. 2015 Feb 23. doi: 10.1002/ps.3995. [Epub ahead of print]

PMID:
25703739
11.

Familiality and SNP heritability of age at onset and episodicity in major depressive disorder.

Ferentinos P, Koukounari A, Power R, Rivera M, Uher R, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Ising M, Maier W, Mors O, Rietschel M, Preisig M, Binder EB, Aitchison KJ, Mendlewicz J, Souery D, Hauser J, Henigsberg N, Breen G, Craig IW, Farmer AE, Müller-Myhsok B, McGuffin P, Lewis CM.

Psychol Med. 2015 Feb 20:1-11. [Epub ahead of print]

12.

Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.

Desikan RS, Schork AJ, Wang Y, Witoelar A, Sharma M, McEvoy LK, Holland D, Brewer JB, Chen CH, Thompson WK, Harold D, Williams J, Owen MJ, O'Donovan MC, Pericak-Vance MA, Mayeux R, Haines JL, Farrer LA, Schellenberg GD, Heutink P, Singleton AB, Brice A, Wood NW, Hardy J, Martinez M, Choi SH, DeStefano A, Ikram MA, Bis JC, Smith A, Fitzpatrick AL, Launer L, van Duijn C, Seshadri S, Ulstein ID, Aarsland D, Fladby T, Djurovic S, Hyman BT, Snaedal J, Stefansson H, Stefansson K, Gasser T, Andreassen OA, Dale AM.

Mol Psychiatry. 2015 Feb 17. doi: 10.1038/mp.2015.6. [Epub ahead of print]

PMID:
25687773
13.

Copy number variation in bipolar disorder.

Green EK, Rees E, Walters JT, Smith KG, Forty L, Grozeva D, Moran JL, Sklar P, Ripke S, Chambert KD, Genovese G, McCarroll SA, Jones I, Jones L, Owen MJ, O'Donovan MC, Craddock N, Kirov G.

Mol Psychiatry. 2015 Jan 6. doi: 10.1038/mp.2014.174. [Epub ahead of print]

PMID:
25560756
14.

Alzheimer's disease risk variant in CLU is associated with neural inefficiency in healthy individuals.

Lancaster TM, Brindley LM, Tansey KE, Sims RC, Mantripragada K, Owen MJ, Williams J, Linden DE.

Alzheimers Dement. 2014 Dec 10. pii: S1552-5260(14)02867-2. doi: 10.1016/j.jalz.2014.10.012. [Epub ahead of print]

PMID:
25496871
15.

New approaches to psychiatric diagnostic classification.

Owen MJ.

Neuron. 2014 Nov 5;84(3):564-71. doi: 10.1016/j.neuron.2014.10.028. Epub 2014 Nov 5. Review.

PMID:
25442935
16.

Schizophrenia genetics: building the foundations of the future.

Tansey KE, Owen MJ, O'Donovan MC.

Schizophr Bull. 2015 Jan;41(1):15-9. doi: 10.1093/schbul/sbu162. Epub 2014 Nov 13. No abstract available.

17.

Schizophrenia genetics: emerging themes for a complex disorder.

Kavanagh DH, Tansey KE, O'Donovan MC, Owen MJ.

Mol Psychiatry. 2015 Feb;20(1):72-6. doi: 10.1038/mp.2014.148. Epub 2014 Nov 11.

PMID:
25385368
18.

Synaptic, transcriptional and chromatin genes disrupted in autism.

De Rubeis S, He X, Goldberg AP, Poultney CS, Samocha K, Cicek AE, Kou Y, Liu L, Fromer M, Walker S, Singh T, Klei L, Kosmicki J, Shih-Chen F, Aleksic B, Biscaldi M, Bolton PF, Brownfeld JM, Cai J, Campbell NG, Carracedo A, Chahrour MH, Chiocchetti AG, Coon H, Crawford EL, Curran SR, Dawson G, Duketis E, Fernandez BA, Gallagher L, Geller E, Guter SJ, Hill RS, Ionita-Laza J, Jimenz Gonzalez P, Kilpinen H, Klauck SM, Kolevzon A, Lee I, Lei I, Lei J, Lehtimäki T, Lin CF, Ma'ayan A, Marshall CR, McInnes AL, Neale B, Owen MJ, Ozaki N, Parellada M, Parr JR, Purcell S, Puura K, Rajagopalan D, Rehnström K, Reichenberg A, Sabo A, Sachse M, Sanders SJ, Schafer C, Schulte-Rüther M, Skuse D, Stevens C, Szatmari P, Tammimies K, Valladares O, Voran A, Li-San W, Weiss LA, Willsey AJ, Yu TW, Yuen RK; DDD Study; Homozygosity Mapping Collaborative for Autism; UK10K Consortium, Cook EH, Freitag CM, Gill M, Hultman CM, Lehner T, Palotie A, Schellenberg GD, Sklar P, State MW, Sutcliffe JS, Walsh CA, Scherer SW, Zwick ME, Barett JC, Cutler DJ, Roeder K, Devlin B, Daly MJ, Buxbaum JD.

Nature. 2014 Nov 13;515(7526):209-15. doi: 10.1038/nature13772. Epub 2014 Oct 29.

19.

SGCE and myoclonus dystonia: motor characteristics, diagnostic criteria and clinical predictors of genotype.

Peall KJ, Kurian MA, Wardle M, Waite AJ, Hedderly T, Lin JP, Smith M, Whone A, Pall H, White C, Lux A, Jardine PE, Lynch B, Kirov G, O'Riordan S, Samuel M, Lynch T, King MD, Chinnery PF, Warner TT, Blake DJ, Owen MJ, Morris HR.

J Neurol. 2014 Dec;261(12):2296-304. doi: 10.1007/s00415-014-7488-3. Epub 2014 Sep 11.

20.

Genetic risk for schizophrenia: convergence on synaptic pathways involved in plasticity.

Hall J, Trent S, Thomas KL, O'Donovan MC, Owen MJ.

Biol Psychiatry. 2015 Jan 1;77(1):52-8. doi: 10.1016/j.biopsych.2014.07.011. Epub 2014 Jul 18. Review.

PMID:
25152434
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