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Higher plasma levels of lysophosphatidylcholine 18:0 are related to a lower risk of common cancers in a prospective metabolomics study.

Kühn T, Floegel A, Sookthai D, Johnson T, Rolle-Kampczyk U, Otto W, von Bergen M, Boeing H, Kaaks R.

BMC Med. 2016 Jan 28;14(1):13. doi: 10.1186/s12916-016-0552-3.


Di-(2-Ethylhexyl)-Phthalate (DEHP) Causes Impaired Adipocyte Function and Alters Serum Metabolites.

Klöting N, Hesselbarth N, Gericke M, Kunath A, Biemann R, Chakaroun R, Kosacka J, Kovacs P, Kern M, Stumvoll M, Fischer B, Rolle-Kampczyk U, Feltens R, Otto W, Wissenbach DK, von Bergen M, Blüher M.

PLoS One. 2015 Dec 2;10(12):e0143190. doi: 10.1371/journal.pone.0143190. eCollection 2015.


Epithelial-mesenchymal transformation markers E-cadherin and survivin predict progression of stage pTa urothelial bladder carcinoma.

Breyer J, Gierth M, Shalekenov S, Aziz A, Schäfer J, Burger M, Denzinger S, Hofstädter F, Giedl C, Otto W.

World J Urol. 2015 Sep 22. [Epub ahead of print]


A switch from epithelial to mesenchymal properties correlates with lymphovascular invasion in squamous cell carcinoma of the penis.

May M, Brookman-May S, Burger M, Koch S, Otto W, Bründl J, Albrecht K, Denzinger S.

Pathol Res Pract. 2015 Sep;211(9):641-5. doi: 10.1016/j.prp.2015.05.007. Epub 2015 May 28.


Corrigendum to "Characteristics and Outcomes of Patients with Clinical T1 Grade 3 Urothelial Carcinoma Treated with Radical Cystectomy: Results from an International Cohort" [Eur Urol 2010;57:300-9].

Fritsche HM, Burger M, Svatek RS, Jeldres C, Karakiewicz PI, Novara G, Skinner E, Denzinger S, Fradet Y, Isbarn H, Bastian PJ, Volkmer BG, Montorsi F, Kassouf W, Tilki D, Otto W, Capitanio U, Izawa JI, Ficarra V, Lerner S, Sagalowsky AI, Schoenberg M, Kamat A, Dinney CP, Lotan Y, Shariat SF.

Eur Urol. 2015 Jul;68(1):171. doi: 10.1016/j.eururo.2015.02.007. Epub 2015 Feb 18. No abstract available.


[Anamnesis, Pathological Assessment, Therapeutic Features and Course of Disease: Retrospective Study on Clinical-Based Factors for Prediction of Cancer-Specific Survival of 378 Patients with Stage pT1 Urothelial Bladder Carcinoma].

Breyer J, Otto W, Hartmann A, Bumes B, Bründl J, Gierth M, Bertz S, Denzinger S, Burger M, Lausenmeyer EM.

Aktuelle Urol. 2015 May;46(3):221-6. doi: 10.1055/s-0035-1549905. Epub 2015 Jun 12. German.


Loss of AQP3 protein expression is associated with worse progression-free and cancer-specific survival in patients with muscle-invasive bladder cancer.

Rubenwolf P, Thomas C, Denzinger S, Hartmann A, Burger M, Georgopoulos NT, Otto W.

World J Urol. 2015 Dec;33(12):1959-64. doi: 10.1007/s00345-015-1574-8. Epub 2015 May 5.


Preoperative anemia is associated with adverse outcome in patients with urothelial carcinoma of the bladder following radical cystectomy.

Gierth M, Mayr R, Aziz A, Krieger S, Wullich B, Pycha A, Lodde M, Salvadori U, Bründl J, Fritsche HM, Hofstädter F, Pawlik MT, Otto W, May M, Burger M, Denzinger S.

J Cancer Res Clin Oncol. 2015 Oct;141(10):1819-26. doi: 10.1007/s00432-015-1957-7. Epub 2015 Apr 2.


[Non-muscle-invasive high-grade bladder cancer].

Gakis G, Stenzl A, Horn T, Gschwend JE, Otto W, Burger M.

Urologe A. 2015 Apr;54(4):491-8. doi: 10.1007/s00120-015-3774-7. German.


Attenuation of Postoperative Acute Liver Failure by Mesenchymal Stem Cell Treatment Due to Metabolic Implications.

Tautenhahn HM, Brückner S, Baumann S, Winkler S, Otto W, von Bergen M, Bartels M, Christ B.

Ann Surg. 2015 Mar 13. [Epub ahead of print]


Low-dose TNF augments fracture healing in normal and osteoporotic bone by up-regulating the innate immune response.

Chan JK, Glass GE, Ersek A, Freidin A, Williams GA, Gowers K, Espirito Santo AI, Jeffery R, Otto WR, Poulsom R, Feldmann M, Rankin SM, Horwood NJ, Nanchahal J.

EMBO Mol Med. 2015 Mar 14;7(5):547-61. doi: 10.15252/emmm.201404487.


Endogenous metabolites and inflammasome activity in early childhood and links to respiratory diseases.

Herberth G, Offenberg K, Rolle-Kampczyk U, Bauer M, Otto W, Röder S, Grützmann K, Sack U, Simon JC, Borte M, von Bergen M, Lehmann I; LINA Study Group.

J Allergy Clin Immunol. 2015 Aug;136(2):495-7. doi: 10.1016/j.jaci.2015.01.022. Epub 2015 Mar 7. No abstract available.


Compartment resolved reference proteome map from highly purified naïve, activated, effector, and memory CD8⁺ murine immune cells.

Zanker D, Otto W, Chen W, von Bergen M, Tomm JM.

Proteomics. 2015 Jun;15(11):1808-12. doi: 10.1002/pmic.201400405. Epub 2015 Mar 3.


Epidermal growth factor attenuates tubular necrosis following mercuric chloride damage by regeneration of indigenous, not bone marrow-derived cells.

Yen TH, Alison MR, Goodlad RA, Otto WR, Jeffery R, Cook HT, Wright NA, Poulsom R.

J Cell Mol Med. 2015 Feb;19(2):463-73. doi: 10.1111/jcmm.12478. Epub 2014 Nov 11.


Pathway and time-resolved benzo[a]pyrene toxicity on Hepa1c1c7 cells at toxic and subtoxic exposure.

Kalkhof S, Dautel F, Loguercio S, Baumann S, Trump S, Jungnickel H, Otto W, Rudzok S, Potratz S, Luch A, Lehmann I, Beyer A, von Bergen M.

J Proteome Res. 2015 Jan 2;14(1):164-82. doi: 10.1021/pr500957t. Epub 2014 Nov 17.


Integration of conventional quantitative and phospho-proteomics reveals new elements in activated Jurkat T-cell receptor pathway maintenance.

Jouy F, Müller SA, Wagner J, Otto W, von Bergen M, Tomm JM.

Proteomics. 2015 Jan;15(1):25-33. doi: 10.1002/pmic.201400119. Epub 2014 Dec 10.


Outcome of patients with pathological tumor stage T3 urothelial carcinoma of the bladder following radical cystectomy in a single-center series with 116 patients.

Breyer J, Denzinger S, Otto W, Bründl J, Gierth M, Fritsche HM, Rößler W, Wieland WF, Giedl C, Hofstädter F, Rubenwolf P, Burger M, Aziz A.

Urol Int. 2014;93(3):311-9. doi: 10.1159/000360483. Epub 2014 Sep 4.


Comparative analysis of gender-related differences in symptoms and referral patterns prior to initial diagnosis of urothelial carcinoma of the bladder: a prospective cohort study.

Aziz A, Madersbacher S, Otto W, Mayr R, Comploj E, Pycha A, Denzinger S, Fritsche HM, Burger M, Gierth M.

Urol Int. 2015;94(1):37-44. doi: 10.1159/000363334. Epub 2014 Aug 13.


The Charlson comorbidity index predicts survival after disease recurrence in patients following radical cystectomy for urothelial carcinoma of the bladder.

Mayr R, May M, Burger M, Martini T, Pycha A, Dechet C, Lodde M, Comploj E, Wieland WF, Denzinger S, Otto W, Aziz A, Fritsche HM, Gierth M.

Urol Int. 2014;93(3):303-10. doi: 10.1159/000362421. Epub 2014 Aug 19.


Preoperative C-reactive protein in the serum: a prognostic biomarker for upper urinary tract urothelial carcinoma treated with radical nephroureterectomy.

Aziz A, Rink M, Gakis G, Kluth LA, Dechet C, Miller F, Otto W, Gierth M, Denzinger S, Schwentner C, Stenzl A, Fisch M, Burger M, Fritsche HM.

Urol Int. 2014;93(3):352-60. doi: 10.1159/000362248. Epub 2014 Aug 19.

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