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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 2
1979 1
1982 2
1983 4
1984 2
1985 2
1986 8
1987 2
1988 9
1989 16
1990 26
1991 29
1992 22
1993 33
1994 44
1995 51
1996 62
1997 59
1998 54
1999 70
2000 81
2001 105
2002 109
2003 100
2004 126
2005 128
2006 129
2007 143
2008 159
2009 133
2010 154
2011 171
2012 181
2013 166
2014 146
2015 141
2016 160
2017 151
2018 144
2019 137
2020 142
2021 113
2022 84
2023 87
2024 30

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3,276 results

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Page 1
Osteoblast-derived VEGF regulates osteoblast differentiation and bone formation during bone repair.
Hu K, Olsen BR. Hu K, et al. J Clin Invest. 2016 Feb;126(2):509-26. doi: 10.1172/JCI82585. Epub 2016 Jan 5. J Clin Invest. 2016. PMID: 26731472 Free PMC article.
Osteoblast-derived VEGF is important for bone development and postnatal bone homeostasis. ...VEGF likely functions as a paracrine factor in this process because deletion of Vegfr2 in osteoblastic lineage cells enhanced osteoblastic maturation and miner …
Osteoblast-derived VEGF is important for bone development and postnatal bone homeostasis. ...VEGF likely functions as a paracrine …
TGF-beta and BMP signaling in osteoblast differentiation and bone formation.
Chen G, Deng C, Li YP. Chen G, et al. Int J Biol Sci. 2012;8(2):272-88. doi: 10.7150/ijbs.2929. Epub 2012 Jan 21. Int J Biol Sci. 2012. PMID: 22298955 Free PMC article. Review.
Transforming growth factor-beta (TGF-beta)/bone morphogenic protein (BMP) signaling is involved in a vast majority of cellular processes and is fundamentally important throughout life. ...This review also highlights the different modes of cross-talk between TGF-beta/BMP si …
Transforming growth factor-beta (TGF-beta)/bone morphogenic protein (BMP) signaling is involved in a vast majority of cellular proces …
MiR-135-5p promotes osteoblast differentiation by targeting HIF1AN in MC3T3-E1 cells.
Yin N, Zhu L, Ding L, Yuan J, Du L, Pan M, Xue F, Xiao H. Yin N, et al. Cell Mol Biol Lett. 2019 Aug 8;24:51. doi: 10.1186/s11658-019-0177-6. eCollection 2019. Cell Mol Biol Lett. 2019. PMID: 31410089 Free PMC article.
BACKGROUND: MicroRNAs (miRNAs or miRs) serve crucial roles in the progression of osteoporosis. This study investigated the role and specific molecular mechanism of miR-135-5p in regulating osteoblast differentiation and calcification. ...Then, miR-135-5p mimic or mi …
BACKGROUND: MicroRNAs (miRNAs or miRs) serve crucial roles in the progression of osteoporosis. This study investigated the role and speci …
Molecular mechanisms of osteoblast-specific transcription factor Osterix effect on bone formation.
Zhang C. Zhang C. Beijing Da Xue Xue Bao Yi Xue Ban. 2012 Oct 18;44(5):659-65. Beijing Da Xue Xue Bao Yi Xue Ban. 2012. PMID: 23073571 Free article. Review.
Bone formation is a complex developmental process involving the differentiation of mesenchymal stem cells to osteoblasts. Osteoblast commitment and differentiation are controlled through a multistep molecular pathway regulated by different transcription factors …
Bone formation is a complex developmental process involving the differentiation of mesenchymal stem cells to osteoblasts. Osteobla …
Regulation of osteoblast development by Bcl-2-associated athanogene-1 (BAG-1).
Greenhough J, Papadakis ES, Cutress RI, Townsend PA, Oreffo ROC, Tare RS. Greenhough J, et al. Sci Rep. 2016 Sep 16;6:33504. doi: 10.1038/srep33504. Sci Rep. 2016. PMID: 27633857 Free PMC article.
BCL-2-associated athanogene-1 (BAG-1) is expressed by osteoblast-lineage cells; early embryonic lethality in Bag-1 null mice, however, has limited the investigation of BAG-1 function in osteoblast development. ...Inhibition of BAG-1 binding to HSC70 by the sm …
BCL-2-associated athanogene-1 (BAG-1) is expressed by osteoblast-lineage cells; early embryonic lethality in Bag-1 null mice, …
Stanniocalcin 2 improved osteoblast differentiation via phosphorylation of ERK.
Zhou J, Li Y, Yang L, Wu Y, Zhou Y, Cui Y, Yang G, Hong Y. Zhou J, et al. Mol Med Rep. 2016 Dec;14(6):5653-5659. doi: 10.3892/mmr.2016.5951. Epub 2016 Nov 16. Mol Med Rep. 2016. PMID: 27878259
Knockdown of STC2 downregulated the expression of osteoblast-associated genes, including runt-related transcription factor 2, collagen type I alpha 1 chain, osterix and osteocalcin. Overexpression of STC2 upregulated the expression of these osteoblastic …
Knockdown of STC2 downregulated the expression of osteoblast-associated genes, including runt-related transcription factor …
The osteoblast-specific transcription factor Cbfa1 contributes to the expression of osteoprotegerin, a potent inhibitor of osteoclast differentiation and function.
Thirunavukkarasu K, Halladay DL, Miles RR, Yang X, Galvin RJ, Chandrasekhar S, Martin TJ, Onyia JE. Thirunavukkarasu K, et al. J Biol Chem. 2000 Aug 18;275(33):25163-72. doi: 10.1074/jbc.M000322200. J Biol Chem. 2000. PMID: 10833509 Free article.
Bone formation and resorption are tightly coupled under normal conditions, and the interaction of osteoclast precursors with cells of the osteoblast lineage is a prerequisite for osteoclast formation. Cbfa1 is an osteoblast-specific transcription factor …
Bone formation and resorption are tightly coupled under normal conditions, and the interaction of osteoclast precursors with cells of the …
PTH-Induced Osteoblast Proliferation Requires Upregulation of the Ubiquitin-Specific Peptidase 2 (Usp2) Expression.
Shirakawa J, Harada H, Noda M, Ezura Y. Shirakawa J, et al. Calcif Tissue Int. 2016 Mar;98(3):306-15. doi: 10.1007/s00223-015-0083-5. Epub 2015 Dec 7. Calcif Tissue Int. 2016. PMID: 26643174
Therefore, in this study, we investigated the effects of PTH on gene expression in the cultured osteoblastic MC3T3-E1 cells, and found that the ubiquitin-specific peptidase 2 (Usp2) may be one of the direct target genes of PTHR signaling. Usp2 is a deubiquiti …
Therefore, in this study, we investigated the effects of PTH on gene expression in the cultured osteoblastic MC3T3-E1 cells, and foun …
Fibroblast growth factor-2 induces osteoblast survival through a phosphatidylinositol 3-kinase-dependent, -beta-catenin-independent signaling pathway.
Debiais F, Lefèvre G, Lemonnier J, Le Mée S, Lasmoles F, Mascarelli F, Marie PJ. Debiais F, et al. Exp Cell Res. 2004 Jul 1;297(1):235-46. doi: 10.1016/j.yexcr.2004.03.032. Exp Cell Res. 2004. PMID: 15194439
Fibroblast growth factor-2 (FGF-2) is an important molecule that controls bone formation through activation of osteoblastic cell replication and differentiation. ...Treatment with FGF-2 for 24-48 h protected against osteoblast apoptosis i …
Fibroblast growth factor-2 (FGF-2) is an important molecule that controls bone formation through activation of osteo …
Osteoblast Ca(2+) permeability and voltage-sensitive Ca(2+) channel expression is temporally regulated by 1,25-dihydroxyvitamin D(3).
Bergh JJ, Shao Y, Puente E, Duncan RL, Farach-Carson MC. Bergh JJ, et al. Am J Physiol Cell Physiol. 2006 Mar;290(3):C822-31. doi: 10.1152/ajpcell.00403.2005. Epub 2005 Oct 12. Am J Physiol Cell Physiol. 2006. PMID: 16221734 Free article.
The cardiac subtype of the L-type voltage-sensitive Ca(2+) channel (VSCC) Cav1.2 (alpha(1C)) is the primary voltage-sensitive channel responsible for Ca(2+) influx into actively proliferating osteoblasts. ...Functional and pharmacological studies using …
The cardiac subtype of the L-type voltage-sensitive Ca(2+) channel (VSCC) Cav1.2 (alpha(1C)) is the primary voltage-sensitive …
3,276 results