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Results: 1 to 20 of 183

1.
2.

Blood-brain barrier pharmacoproteomics-based reconstruction of the in vivo brain distribution of p-glycoprotein substrates in cynomolgus monkeys.

Uchida Y, Wakayama K, Ohtsuki S, Chiba M, Ohe T, Ishii Y, Terasaki T.

J Pharmacol Exp Ther. 2014 Sep;350(3):578-88. doi: 10.1124/jpet.114.214536. Epub 2014 Jun 19.

PMID:
24947467
[PubMed - in process]
Free Article
3.

Mutations of NOTCH3 in childhood pulmonary arterial hypertension.

Chida A, Shintani M, Matsushita Y, Sato H, Eitoku T, Nakayama T, Furutani Y, Hayama E, Kawamura Y, Inai K, Ohtsuki S, Saji T, Nonoyama S, Nakanishi T.

Mol Genet Genomic Med. 2014 May;2(3):229-39. doi: 10.1002/mgg3.58. Epub 2014 Apr 1.

PMID:
24936512
[PubMed]
Free PMC Article
4.

Non-uniform distribution of the contraction/extension (C-E) in the left ventricular myocardium related to the myocardial function.

Tanaka M, Sakamoto T, Katahira Y, Tabuchi H, Nakajima H, Kurokawa T, Kanai H, Hasegawa H, Ohtsuki S.

J Cardiol. 2014 May 15. pii: S0914-5087(14)00088-4. doi: 10.1016/j.jjcc.2014.02.024. [Epub ahead of print]

PMID:
24836654
[PubMed - as supplied by publisher]
5.

Validation of uPA/SCID mouse with humanized liver as a human liver model: protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases by LC-MS/MS.

Ohtsuki S, Kawakami H, Inoue T, Nakamura K, Tateno C, Katsukura Y, Obuchi W, Uchida Y, Kamiie J, Horie T, Terasaki T.

Drug Metab Dispos. 2014 Jun;42(6):1039-43. doi: 10.1124/dmd.114.057646. Epub 2014 Apr 7.

PMID:
24711249
[PubMed - in process]
6.

Quantitative targeted proteomics for understanding the blood-brain barrier: towards pharmacoproteomics.

Ohtsuki S, Hirayama M, Ito S, Uchida Y, Tachikawa M, Terasaki T.

Expert Rev Proteomics. 2014 Jun;11(3):303-13. doi: 10.1586/14789450.2014.893830. Epub 2014 Apr 4.

PMID:
24702234
[PubMed - in process]
7.

A new concept of the contraction-extension property of the left ventricular myocardium.

Tanaka M, Sakamoto T, Sugawara S, Katahira Y, Tabuchi H, Nakajima H, Kurokawa T, Kanai H, Hasegawa H, Ohtsuki S.

J Cardiol. 2014 Apr;63(4):313-9. doi: 10.1016/j.jjcc.2013.09.009. Epub 2013 Nov 27.

PMID:
24290368
[PubMed - in process]
8.

Contributions of degradation and brain-to-blood elimination across the blood-brain barrier to cerebral clearance of human amyloid-β peptide(1-40) in mouse brain.

Ito S, Matsumiya K, Ohtsuki S, Kamiie J, Terasaki T.

J Cereb Blood Flow Metab. 2013 Nov;33(11):1770-7. doi: 10.1038/jcbfm.2013.125. Epub 2013 Aug 21.

PMID:
23963369
[PubMed - indexed for MEDLINE]
9.

Involvement of insulin-degrading enzyme in insulin- and atrial natriuretic peptide-sensitive internalization of amyloid-β peptide in mouse brain capillary endothelial cells.

Ito S, Ohtsuki S, Murata S, Katsukura Y, Suzuki H, Funaki M, Tachikawa M, Terasaki T.

J Alzheimers Dis. 2014;38(1):185-200. doi: 10.3233/JAD-122077.

PMID:
23948938
[PubMed - indexed for MEDLINE]
11.

Quantitative expression of human drug transporter proteins in lung tissues: analysis of regional, gender, and interindividual differences by liquid chromatography-tandem mass spectrometry.

Sakamoto A, Matsumaru T, Yamamura N, Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T.

J Pharm Sci. 2013 Sep;102(9):3395-406. doi: 10.1002/jps.23606. Epub 2013 May 13.

PMID:
23670800
[PubMed - indexed for MEDLINE]
12.

Quantitative atlas of blood-brain barrier transporters, receptors, and tight junction proteins in rats and common marmoset.

Hoshi Y, Uchida Y, Tachikawa M, Inoue T, Ohtsuki S, Terasaki T.

J Pharm Sci. 2013 Sep;102(9):3343-55. doi: 10.1002/jps.23575. Epub 2013 May 6.

PMID:
23650139
[PubMed - indexed for MEDLINE]
13.

[Novel approach for biochemistry by quantitative targeted proteomics: new protein quantification method without using antibodies].

Ohtsuki S.

Seikagaku. 2012 Nov;84(11):911-9. Review. Japanese. No abstract available.

PMID:
23379224
[PubMed - indexed for MEDLINE]
14.

Quantitative targeted absolute proteomics-based large-scale quantification of proline-hydroxylated α-fibrinogen in plasma for pancreatic cancer diagnosis.

Yoneyama T, Ohtsuki S, Ono M, Ohmine K, Uchida Y, Yamada T, Tachikawa M, Terasaki T.

J Proteome Res. 2013 Feb 1;12(2):753-62. doi: 10.1021/pr3008144. Epub 2013 Jan 18.

PMID:
23298340
[PubMed - indexed for MEDLINE]
15.

Identification of transporters associated with Etoposide sensitivity of stomach cancer cell lines and methotrexate sensitivity of breast cancer cell lines by quantitative targeted absolute proteomics.

Obuchi W, Ohtsuki S, Uchida Y, Ohmine K, Yamori T, Terasaki T.

Mol Pharmacol. 2013 Feb;83(2):490-500. doi: 10.1124/mol.112.081083. Epub 2012 Nov 29.

PMID:
23197647
[PubMed - indexed for MEDLINE]
Free Article
16.

Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.

Ohtsuki S, Ikeda C, Uchida Y, Sakamoto Y, Miller F, Glacial F, Decleves X, Scherrmann JM, Couraud PO, Kubo Y, Tachikawa M, Terasaki T.

Mol Pharm. 2013 Jan 7;10(1):289-96. doi: 10.1021/mp3004308. Epub 2012 Dec 11.

PMID:
23137377
[PubMed - indexed for MEDLINE]
17.

Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans.

Kazuki Y, Kobayashi K, Aueviriyavit S, Oshima T, Kuroiwa Y, Tsukazaki Y, Senda N, Kawakami H, Ohtsuki S, Abe S, Takiguchi M, Hoshiya H, Kajitani N, Takehara S, Kubo K, Terasaki T, Chiba K, Tomizuka K, Oshimura M.

Hum Mol Genet. 2013 Feb 1;22(3):578-92. doi: 10.1093/hmg/dds468. Epub 2012 Nov 2.

PMID:
23125282
[PubMed - indexed for MEDLINE]
Free Article
18.

Usefulness of balloon angioplasty for the right ventricle-pulmonary artery shunt with the modified Norwood procedure.

Ohno N, Ohtsuki S, Kataoka K, Baba K, Okamoto Y, Kondo M, Sano S, Kasahara S, Honjo O, Morishima T.

Catheter Cardiovasc Interv. 2013 Apr;81(5):837-42. doi: 10.1002/ccd.24576. Epub 2012 Sep 17.

PMID:
22887865
[PubMed - indexed for MEDLINE]
19.

Outcomes of childhood pulmonary arterial hypertension in BMPR2 and ALK1 mutation carriers.

Chida A, Shintani M, Yagi H, Fujiwara M, Kojima Y, Sato H, Imamura S, Yokozawa M, Onodera N, Horigome H, Kobayashi T, Hatai Y, Nakayama T, Fukushima H, Nishiyama M, Doi S, Ono Y, Yasukouchi S, Ichida F, Fujimoto K, Ohtsuki S, Teshima H, Kawano T, Nomura Y, Gu H, Ishiwata T, Furutani Y, Inai K, Saji T, Matsuoka R, Nonoyama S, Nakanishi T.

Am J Cardiol. 2012 Aug 15;110(4):586-93. doi: 10.1016/j.amjcard.2012.04.035. Epub 2012 May 25. Erratum in: Am J Cardiol. 2013 Feb 15;111(4):630.

PMID:
22632830
[PubMed - indexed for MEDLINE]
20.

Biological activity of SE-10, granulated powder of Sasa senanensis Rehder leaf extract.

Sakagami H, Matsuta T, Satoh K, Ohtsuki S, Shimada C, Kanamoto T, Terakubo S, Nakashima H, Morita Y, Ohkubo A, Tsuda T, Sunaga K, Maki J, Sugiura T, Kitajima M, Oizumi H, Oizumi T.

In Vivo. 2012 May-Jun;26(3):411-8.

PMID:
22523293
[PubMed - indexed for MEDLINE]

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