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Results: 1 to 20 of 209

1.

Niacin Activates the PI3K/Akt Cascade via PKC- and EGFR-Transactivation-Dependent Pathways through Hydroxyl-Carboxylic Acid Receptor 2.

Sun H, Li G, Zhang W, Zhou Q, Yu Y, Shi Y, Offermanns S, Lu J, Zhou N.

PLoS One. 2014 Nov 6;9(11):e112310. doi: 10.1371/journal.pone.0112310. eCollection 2014.

PMID:
25375133
[PubMed - in process]
Free PMC Article
2.

Previously differentiated medial vascular smooth muscle cells contribute to neointima formation following vascular injury.

Herring BP, Hoggatt AM, Burlak C, Offermanns S.

Vasc Cell. 2014 Oct 1;6:21. doi: 10.1186/2045-824X-6-21. eCollection 2014.

PMID:
25309723
[PubMed]
Free PMC Article
3.

Genetic dissection of the vav2-rac1 signaling axis in vascular smooth muscle cells.

Fabbiano S, Menacho-Márquez M, Sevilla MA, Albarrán-Juárez J, Zheng Y, Offermanns S, Montero MJ, Bustelo XR.

Mol Cell Biol. 2014 Dec 15;34(24):4404-19. doi: 10.1128/MCB.01066-14. Epub 2014 Oct 6.

PMID:
25288640
[PubMed - in process]
4.

The IκB kinase complex is required for plexin-B-mediated activation of RhoA.

Zielonka M, Krishnan RK, Swiercz JM, Offermanns S.

PLoS One. 2014 Aug 19;9(8):e105661. doi: 10.1371/journal.pone.0105661. eCollection 2014.

PMID:
25137062
[PubMed - in process]
Free PMC Article
5.

Semaphorins and plexins as therapeutic targets.

Worzfeld T, Offermanns S.

Nat Rev Drug Discov. 2014 Aug;13(8):603-21. doi: 10.1038/nrd4337. Review.

PMID:
25082288
[PubMed - indexed for MEDLINE]
6.

Vitamin D promotes vascular regeneration.

Wong MS, Leisegang MS, Kruse C, Vogel J, Schürmann C, Dehne N, Weigert A, Herrmann E, Brüne B, Shah AM, Steinhilber D, Offermanns S, Carmeliet G, Badenhoop K, Schröder K, Brandes RP.

Circulation. 2014 Sep 16;130(12):976-86. doi: 10.1161/CIRCULATIONAHA.114.010650. Epub 2014 Jul 11.

PMID:
25015343
[PubMed - indexed for MEDLINE]
7.

Smooth muscle specific Rac1 deficiency induces hypertension by preventing p116RIP3-dependent RhoA inhibition.

André G, Sandoval JE, Retailleau K, Loufrani L, Toumaniantz G, Offermanns S, Rolli-Derkinderen M, Loirand G, Sauzeau V.

J Am Heart Assoc. 2014 Jun 17;3(3):e000852. doi: 10.1161/JAHA.114.000852.

PMID:
24938713
[PubMed - in process]
Free Article
8.

The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages.

Rahman M, Muhammad S, Khan MA, Chen H, Ridder DA, Müller-Fielitz H, Pokorná B, Vollbrandt T, Stölting I, Nadrowitz R, Okun JG, Offermanns S, Schwaninger M.

Nat Commun. 2014 May 21;5:3944. doi: 10.1038/ncomms4944.

PMID:
24845831
[PubMed - in process]
9.

Heating up the cutaneous flushing response.

Offermanns S.

Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1122-3. doi: 10.1161/ATVBAHA.114.303742. No abstract available.

PMID:
24828517
[PubMed - indexed for MEDLINE]
10.

Identification of Hic-5 as a novel scaffold for the MKK4/p54 JNK pathway in the development of abdominal aortic aneurysms.

Lei XF, Kim-Kaneyama JR, Arita-Okubo S, Offermanns S, Itabe H, Miyazaki T, Miyazaki A.

J Am Heart Assoc. 2014 May 8;3(3):e000747. doi: 10.1161/JAHA.113.000747.

PMID:
24811612
[PubMed - in process]
Free Article
11.

G-protein stimulatory subunit alpha and Gq/11α G-proteins are both required to maintain quiescent stem-like chondrocytes.

Chagin AS, Vuppalapati KK, Kobayashi T, Guo J, Hirai T, Chen M, Offermanns S, Weinstein LS, Kronenberg HM.

Nat Commun. 2014 Apr 30;5:3673. doi: 10.1038/ncomms4673.

PMID:
24781502
[PubMed - in process]
12.

Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE.

Chen H, Assmann JC, Krenz A, Rahman M, Grimm M, Karsten CM, Köhl J, Offermanns S, Wettschureck N, Schwaninger M.

J Clin Invest. 2014 May 1;124(5):2188-92. Epub 2014 Apr 1.

PMID:
24691444
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A novel luminescence-based method for the detection of functionally active antibodies to muscarinic acetylcholine receptors of the M3 type (mAchR3) in patients' sera.

Preuss B, Tunaru S, Henes J, Offermanns S, Klein R.

Clin Exp Immunol. 2014 Jul;177(1):179-89. doi: 10.1111/cei.12324.

PMID:
24628494
[PubMed - indexed for MEDLINE]
14.

The Concise Guide to PHARMACOLOGY 2013/14: overview.

Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, McGrath JC, Catterall WA, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators, Abul-Hasn N, Anderson CM, Anderson CM, Araiksinen MS, Arita M, Arthofer E, Barker EL, Barratt C, Barnes NM, Bathgate R, Beart PM, Belelli D, Bennett AJ, Birdsall NJ, Boison D, Bonner TI, Brailsford L, Bröer S, Brown P, Calo G, Carter WG, Catterall WA, Chan SL, Chao MV, Chiang N, Christopoulos A, Chun JJ, Cidlowski J, Clapham DE, Cockcroft S, Connor MA, Cox HM, Cuthbert A, Dautzenberg FM, Davenport AP, Dawson PA, Dent G, Dijksterhuis JP, Dollery CT, Dolphin AC, Donowitz M, Dubocovich ML, Eiden L, Eidne K, Evans BA, Fabbro D, Fahlke C, Farndale R, Fitzgerald GA, Fong TM, Fowler CJ, Fry JR, Funk CD, Futerman AH, Ganapathy V, Gaisnier B, Gershengorn MA, Goldin A, Goldman ID, Gundlach AL, Hagenbuch B, Hales TG, Hammond JR, Hamon M, Hancox JC, Hauger RL, Hay DL, Hobbs AJ, Hollenberg MD, Holliday ND, Hoyer D, Hynes NA, Inui KI, Ishii S, Jacobson KA, Jarvis GE, Jarvis MF, Jensen R, Jones CE, Jones RL, Kaibuchi K, Kanai Y, Kennedy C, Kerr ID, Khan AA, Klienz MJ, Kukkonen JP, Lapoint JY, Leurs R, Lingueglia E, Lippiat J, Lolait SJ, Lummis SC, Lynch JW, MacEwan D, Maguire JJ, Marshall IL, May JM, McArdle CA, McGrath JC, Michel MC, Millar NS, Miller LJ, Mitolo V, Monk PN, Moore PK, Moorhouse AJ, Mouillac B, Murphy PM, Neubig RR, Neumaier J, Niesler B, Obaidat A, Offermanns S, Ohlstein E, Panaro MA, Parsons S, Pwrtwee RG, Petersen J, Pin JP, Poyner DR, Prigent S, Prossnitz ER, Pyne NJ, Pyne S, Quigley JG, Ramachandran R, Richelson EL, Roberts RE, Roskoski R, Ross RA, Roth M, Rudnick G, Ryan RM, Said SI, Schild L, Sanger GJ, Scholich K, Schousboe A, Schulte G, Schulz S, Serhan CN, Sexton PM, Sibley DR, Siegel JM, Singh G, Sitsapesan R, Smart TG, Smith DM, Soga T, Stahl A, Stewart G, Stoddart LA, Summers RJ, Thorens B, Thwaites DT, Toll L, Traynor JR, Usdin TB, Vandenberg RJ, Villalon C, Vore M, Waldman SA, Ward DT, Willars GB, Wonnacott SJ, Wright E, Ye RD, Yonezawa A, Zimmermann M.

Br J Pharmacol. 2013 Dec;170(8):1449-58. doi: 10.1111/bph.12444.

PMID:
24528237
[PubMed - indexed for MEDLINE]
15.

Genetic dissection of plexin signaling in vivo.

Worzfeld T, Swiercz JM, Sentürk A, Genz B, Korostylev A, Deng S, Xia J, Hoshino M, Epstein JA, Chan AM, Vollmar B, Acker-Palmer A, Kuner R, Offermanns S.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2194-9. doi: 10.1073/pnas.1308418111. Epub 2014 Jan 27.

PMID:
24469813
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.

Singh N, Gurav A, Sivaprakasam S, Brady E, Padia R, Shi H, Thangaraju M, Prasad PD, Manicassamy S, Munn DH, Lee JR, Offermanns S, Ganapathy V.

Immunity. 2014 Jan 16;40(1):128-39. doi: 10.1016/j.immuni.2013.12.007. Epub 2014 Jan 9.

PMID:
24412617
[PubMed - indexed for MEDLINE]
17.

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis.

Li W, Li Q, Jiao Y, Qin L, Ali R, Zhou J, Ferruzzi J, Kim RW, Geirsson A, Dietz HC, Offermanns S, Humphrey JD, Tellides G.

J Clin Invest. 2014 Feb 3;124(2):755-67. doi: 10.1172/JCI69942. Epub 2014 Jan 9.

PMID:
24401272
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A mouse model with tamoxifen-inducible thyrocyte-specific cre recombinase activity.

Undeutsch H, Löf C, Offermanns S, Kero J.

Genesis. 2014 Apr;52(4):333-40. doi: 10.1002/dvg.22740. Epub 2014 Jan 15.

PMID:
24395757
[PubMed - in process]
19.

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition.

Chang PV, Hao L, Offermanns S, Medzhitov R.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2247-52. doi: 10.1073/pnas.1322269111. Epub 2014 Jan 3.

PMID:
24390544
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells.

Engelstoft MS, Park WM, Sakata I, Kristensen LV, Husted AS, Osborne-Lawrence S, Piper PK, Walker AK, Pedersen MH, Nøhr MK, Pan J, Sinz CJ, Carrington PE, Akiyama TE, Jones RM, Tang C, Ahmed K, Offermanns S, Egerod KL, Zigman JM, Schwartz TW.

Mol Metab. 2013 Sep 4;2(4):376-92. doi: 10.1016/j.molmet.2013.08.006. eCollection 2013.

PMID:
24327954
[PubMed]
Free PMC Article

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