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Results: 1 to 20 of 25


Stromal transcriptional profiles reveal hierarchies of anatomical site, serum response and disease and identify disease specific pathways.

Filer A, Antczak P, Parsonage GN, Legault HM, O'Toole M, Pearson MJ, Thomas AM, Scheel-Toellner D, Raza K, Buckley CD, Falciani F.

PLoS One. 2015 Mar 25;10(3):e0120917. doi: 10.1371/journal.pone.0120917. eCollection 2015.


Estimating trans-seasonal variability in water column biomass for a highly migratory, deep diving predator.

O'Toole MD, Lea MA, Guinet C, Hindell MA.

PLoS One. 2014 Nov 26;9(11):e113171. doi: 10.1371/journal.pone.0113171. eCollection 2014.


Ultrastructural and cellular basis for the development of abnormal myocardial mechanics during the transition from hypertension to heart failure.

Shah SJ, Aistrup GL, Gupta DK, O'Toole MJ, Nahhas AF, Schuster D, Chirayil N, Bassi N, Ramakrishna S, Beussink L, Misener S, Kane B, Wang D, Randolph B, Ito A, Wu M, Akintilo L, Mongkolrattanothai T, Reddy M, Kumar M, Arora R, Ng J, Wasserstrom JA.

Am J Physiol Heart Circ Physiol. 2014 Jan 1;306(1):H88-100. doi: 10.1152/ajpheart.00642.2013. Epub 2013 Nov 1.


The balance of expression of PTPN22 splice forms is significantly different in rheumatoid arthritis patients compared with controls.

Ronninger M, Guo Y, Shchetynsky K, Hill A, Khademi M, Olsson T, Reddy PS, Seddighzadeh M, Clark JD, Lin LL, O'Toole M, Padyukov L.

Genome Med. 2012 Jan 20;4(1):2. doi: 10.1186/gm301.


Building care systems to improve access for high-risk and vulnerable veteran populations.

O'Toole TP, Pirraglia PA, Dosa D, Bourgault C, Redihan S, O'Toole MB, Blumen J; Primary Care-Special Populations Treatment Team.

J Gen Intern Med. 2011 Nov;26 Suppl 2:683-8. doi: 10.1007/s11606-011-1818-2.


Pathways activated during human asthma exacerbation as revealed by gene expression patterns in blood.

Bjornsdottir US, Holgate ST, Reddy PS, Hill AA, McKee CM, Csimma CI, Weaver AA, Legault HM, Small CG, Ramsey RC, Ellis DK, Burke CM, Thompson PJ, Howarth PH, Wardlaw AJ, Bardin PG, Bernstein DI, Irving LB, Chupp GL, Bensch GW, Bensch GW, Stahlman JE, Karetzky M, Baker JW, Miller RL, Goodman BH, Raible DG, Goldman SJ, Miller DK, Ryan JL, Dorner AJ, Immermann FW, O'Toole M.

PLoS One. 2011;6(7):e21902. doi: 10.1371/journal.pone.0021902. Epub 2011 Jul 14.


The role of stretching in slow axonal transport.

O'Toole M, Miller KE.

Biophys J. 2011 Jan 19;100(2):351-60. doi: 10.1016/j.bpj.2010.12.3695.


Slowing of axonal regeneration is correlated with increased axonal viscosity during aging.

Lamoureux PL, O'Toole MR, Heidemann SR, Miller KE.

BMC Neurosci. 2010 Oct 25;11:140. doi: 10.1186/1471-2202-11-140.


Variability in timing of spontaneous calcium release in the intact rat heart is determined by the time course of sarcoplasmic reticulum calcium load.

Wasserstrom JA, Shiferaw Y, Chen W, Ramakrishna S, Patel H, Kelly JE, O'Toole MJ, Pappas A, Chirayil N, Bassi N, Akintilo L, Wu M, Arora R, Aistrup GL.

Circ Res. 2010 Oct 29;107(9):1117-26. doi: 10.1161/CIRCRESAHA.110.229294. Epub 2010 Sep 9.


Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood.

Arai M, Jain S, Weaver AA, Hill AA, Guo Y, Bree AG, Smith MF Jr, Allen SW, LaVallie ER, Young D, Bloom L, Adkins K, O'Toole M.

J Transl Med. 2010 May 28;8:51. doi: 10.1186/1479-5876-8-51.


Assessing agonistic potential of a candidate therapeutic anti-IL21R antibody.

Guo Y, Hill AA, Ramsey RC, Immermann FW, Corcoran C, Young D, Lavallie ER, Ryan M, Bechard T, Pfeifer R, Warner G, Bologna M, Bloom L, O'Toole M.

J Transl Med. 2010 May 26;8:50. doi: 10.1186/1479-5876-8-50.


Correlation of pharmacodynamic activity, pharmacokinetics, and anti-product antibody responses to anti-IL-21R antibody therapeutics following IV administration to cynomolgus monkeys.

Vugmeyster Y, Allen S, Szklut P, Bree A, Ryan M, Ma M, Spaulding V, Young D, Guay H, Bloom L, Leach MW, O'Toole M, Adkins K.

J Transl Med. 2010 Apr 26;8:41. doi: 10.1186/1479-5876-8-41.


A diabetes self-management program designed for urban American Indians.

Castro S, O'Toole M, Brownson C, Plessel K, Schauben L.

Prev Chronic Dis. 2009 Oct;6(4):A131. Epub 2009 Sep 15.


Substrate binding preferences and pka determinations of a nitrile hydratase model complex: variable solvent coordination to [(bmmp-TASN)Fe]OTf.

O'Toole MG, Bennett B, Mashuta MS, Grapperhaus CA.

Inorg Chem. 2009 Mar 2;48(5):2300-8. doi: 10.1021/ic802180d.


Mapping similarities in mTOR pathway perturbations in mouse lupus nephritis models and human lupus nephritis.

Reddy PS, Legault HM, Sypek JP, Collins MJ, Goad E, Goldman SJ, Liu W, Murray S, Dorner AJ, O'Toole M.

Arthritis Res Ther. 2008;10(6):R127. doi: 10.1186/ar2541. Epub 2008 Nov 3. Erratum in: Arthritis Res Ther. 2009;11(2):407.


In vitro allergen challenge of peripheral blood induces differential gene expression in mononuclear cells of asthmatic patients: inhibition of cytosolic phospholipase A2alpha overcomes the asthma-associated response.

Whalen KA, Legault H, Hang C, Hill A, Kasaian M, Donaldson D, Bensch GW, Bensch G, Baker J, Reddy PS, Wood N, Ramarao MK, Ellis DK, Csimma C, McKee C, Clark JD, Ryan J, Dorner AJ, O'Toole M.

Clin Exp Allergy. 2008 Oct;38(10):1590-605. doi: 10.1111/j.1365-2222.2008.03059.x. Epub 2008 Jul 28.


A novel and sensitive ELISA reveals that the soluble form of IL-13R-alpha2 is not expressed in plasma of healthy or asthmatic subjects.

O'Toole M, Legault H, Ramsey R, Wynn TA, Kasaian MT.

Clin Exp Allergy. 2008 Apr;38(4):594-601. doi: 10.1111/j.1365-2222.2007.02921.x. Epub 2008 Feb 25.


Cross-species EST alignments reveal novel and conserved alternative splicing events in legumes.

Wang BB, O'Toole M, Brendel V, Young ND.

BMC Plant Biol. 2008 Feb 19;8:17. doi: 10.1186/1471-2229-8-17.


A physical model of axonal elongation: force, viscosity, and adhesions govern the mode of outgrowth.

O'Toole M, Lamoureux P, Miller KE.

Biophys J. 2008 Apr 1;94(7):2610-20. doi: 10.1529/biophysj.107.117424. Epub 2008 Jan 4.


Ecological approaches to self-management: the case of diabetes.

Fisher EB, Brownson CA, O'Toole ML, Shetty G, Anwuri VV, Glasgow RE.

Am J Public Health. 2005 Sep;95(9):1523-35. Epub 2005 Jul 28. Review.

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