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Results: 1 to 20 of 22

1.

Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment.

Mathews RJ, Robinson JI, Battellino M, Wong C, Taylor JC; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS), Eyre S, Churchman SM, Wilson AG, Isaacs JD, Hyrich K, Barton A, Plant D, Savic S, Cook GP, Sarzi-Puttini P, Emery P, Barrett JH, Morgan AW, McDermott MF.

Ann Rheum Dis. 2014 Jun;73(6):1202-10. doi: 10.1136/annrheumdis-2013-203276. Epub 2013 May 17.

PMID:
23687262
[PubMed - in process]
2.

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.

Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, Zhernakova A, Stahl E, Viatte S, McAllister K, Amos CI, Padyukov L, Toes RE, Huizinga TW, Wijmenga C, Trynka G, Franke L, Westra HJ, Alfredsson L, Hu X, Sandor C, de Bakker PI, Davila S, Khor CC, Heng KK, Andrews R, Edkins S, Hunt SE, Langford C, Symmons D; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate; Wellcome Trust Case Control Consortium, Concannon P, Onengut-Gumuscu S, Rich SS, Deloukas P, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Ärlsetig L, Martin J, Rantapää-Dahlqvist S, Plenge RM, Raychaudhuri S, Klareskog L, Gregersen PK, Worthington J.

Nat Genet. 2012 Dec;44(12):1336-40. doi: 10.1038/ng.2462. Epub 2012 Nov 11.

PMID:
23143596
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Heterogeneity of anticitrullinated peptide antibodies and response to anti-tumor necrosis factor agents in rheumatoid arthritis.

Fisher BA, Plant D, Lundberg K, Charles P, Barton A, Venables PJ; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS).

J Rheumatol. 2012 May;39(5):929-32. doi: 10.3899/jrheum.111315. Epub 2012 Apr 1.

PMID:
22467927
[PubMed - indexed for MEDLINE]
4.

Genome-wide association study of genetic predictors of anti-tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci.

Plant D, Bowes J, Potter C, Hyrich KL, Morgan AW, Wilson AG, Isaacs JD; Wellcome Trust Case Control Consortium; British Society for Rheumatology Biologics Register, Barton A.

Arthritis Rheum. 2011 Mar;63(3):645-53. doi: 10.1002/art.30130.

PMID:
21061259
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis.

Hassan B, Maxwell JR, Hyrich KL; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate, Barton A, Worthington J, Isaacs JD, Morgan AW, Wilson AG.

Rheumatology (Oxford). 2010 Jan;49(1):43-7. doi: 10.1093/rheumatology/kep372. Epub 2009 Nov 19.

PMID:
19926672
[PubMed - indexed for MEDLINE]
Free Article
6.

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk.

Raychaudhuri S, Thomson BP, Remmers EF, Eyre S, Hinks A, Guiducci C, Catanese JJ, Xie G, Stahl EA, Chen R, Alfredsson L, Amos CI, Ardlie KG; BIRAC Consortium, Barton A, Bowes J, Burtt NP, Chang M, Coblyn J, Costenbader KH, Criswell LA, Crusius JB, Cui J, De Jager PL, Ding B, Emery P, Flynn E, Harrison P, Hocking LJ, Huizinga TW, Kastner DL, Ke X, Kurreeman FA, Lee AT, Liu X, Li Y, Martin P, Morgan AW, Padyukov L, Reid DM, Seielstad M, Seldin MF, Shadick NA, Steer S, Tak PP, Thomson W, van der Helm-van Mil AH, van der Horst-Bruinsma IE, Weinblatt ME, Wilson AG, Wolbink GJ, Wordsworth P; YEAR Consortium, Altshuler D, Karlson EW, Toes RE, de Vries N, Begovich AB, Siminovitch KA, Worthington J, Klareskog L, Gregersen PK, Daly MJ, Plenge RM.

Nat Genet. 2009 Dec;41(12):1313-8. doi: 10.1038/ng.479. Epub 2009 Nov 8.

PMID:
19898481
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci.

McClure A, Lunt M, Eyre S, Ke X, Thomson W, Hinks A, Bowes J, Gibbons L, Plant D, Wilson AG, Marinou I, Morgan AW, Emery P; BIRAC consortium, Steer S, Hocking LJ, Reid DM, Wordsworth P, Harrison P, Worthington J, Barton A.

Rheumatology (Oxford). 2009 Nov;48(11):1369-74. doi: 10.1093/rheumatology/kep272. Epub 2009 Sep 9. Erratum in: Rheumatology (Oxford). 2011 Jun;50(6):1178.

PMID:
19741008
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population.

Burr ML, Naseem H, Hinks A, Eyre S, Gibbons LJ, Bowes J, Wilson AG, Maxwell J, Morgan AW, Emery P, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Thomson W, Worthington J; BIRAC Consortium; YEAR Consortium, Barton A.

Ann Rheum Dis. 2010 Apr;69(4):666-70. doi: 10.1136/ard.2009.111294. Epub 2009 May 25. Erratum in: Ann Rheum Dis. 2011 Aug;70(8):1519.

PMID:
19470526
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients.

Bowes JD, Potter C, Gibbons LJ, Hyrich K, Plant D, Morgan AW, Wilson AG, Isaacs JD, Worthington J, Barton A; BRAGGSS.

Pharmacogenet Genomics. 2009 Apr;19(4):319-23. doi: 10.1097/FPC.0b013e328328d51f.

PMID:
19262425
[PubMed - indexed for MEDLINE]
10.

Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.

Barton A, Thomson W, Ke X, Eyre S, Hinks A, Bowes J, Plant D, Gibbons LJ; Wellcome Trust Case Control Consortium; YEAR Consortium; BIRAC Consortium, Wilson AG, Bax DE, Morgan AW, Emery P, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Worthington J.

Nat Genet. 2008 Oct;40(10):1156-9. doi: 10.1038/ng.218. Epub 2008 Sep 14.

PMID:
18794857
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Association of the tumour necrosis factor-308 variant with differential response to anti-TNF agents in the treatment of rheumatoid arthritis.

Maxwell JR, Potter C, Hyrich KL; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate, Barton A, Worthington J, Isaacs JD, Morgan AW, Wilson AG.

Hum Mol Genet. 2008 Nov 15;17(22):3532-8. doi: 10.1093/hmg/ddn245. Epub 2008 Aug 19.

PMID:
18713756
[PubMed - indexed for MEDLINE]
Free Article
12.

Association of rheumatoid factor and anti-cyclic citrullinated peptide positivity, but not carriage of shared epitope or PTPN22 susceptibility variants, with anti-tumour necrosis factor response in rheumatoid arthritis.

Potter C, Hyrich KL, Tracey A, Lunt M, Plant D, Symmons DP, Thomson W, Worthington J, Emery P, Morgan AW, Wilson AG, Isaacs J, Barton A; BRAGGSS.

Ann Rheum Dis. 2009 Jan;68(1):69-74. doi: 10.1136/ard.2007.084715. Epub 2008 Mar 28. Erratum in: Ann Rheum Dis. 2011 Aug;70(8):1519.

PMID:
18375541
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Design and validation of 2 objective structured clinical examination stations to assess core undergraduate examination skills of the hand and knee.

Raj N, Badcock LJ, Brown GA, Deighton CM, O'Reilly SC.

J Rheumatol. 2007 Feb;34(2):421-4.

PMID:
17304661
[PubMed - indexed for MEDLINE]
14.

Undergraduate musculoskeletal examination teaching by trained patient educators--a comparison with doctor-led teaching.

Raj N, Badcock LJ, Brown GA, Deighton CM, O'Reilly SC.

Rheumatology (Oxford). 2006 Nov;45(11):1404-8. Epub 2006 Apr 13.

PMID:
16613915
[PubMed - indexed for MEDLINE]
Free Article
15.

Cost effectiveness of a two-year home exercise program for the treatment of knee pain.

Thomas KS, Miller P, Doherty M, Muir KR, Jones AC, O'Reilly SC.

Arthritis Rheum. 2005 Jun 15;53(3):388-94.

PMID:
15934131
[PubMed - indexed for MEDLINE]
Free Article
16.

Home based exercise programme for knee pain and knee osteoarthritis: randomised controlled trial.

Thomas KS, Muir KR, Doherty M, Jones AC, O'Reilly SC, Bassey EJ.

BMJ. 2002 Oct 5;325(7367):752.

PMID:
12364304
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Occupation and knee pain: a community study.

O'Reilly SC, Muir KR, Doherty M.

Osteoarthritis Cartilage. 2000 Mar;8(2):78-81.

PMID:
10772236
[PubMed - indexed for MEDLINE]
Free Article
18.

Effectiveness of home exercise on pain and disability from osteoarthritis of the knee: a randomised controlled trial.

O'Reilly SC, Muir KR, Doherty M.

Ann Rheum Dis. 1999 Jan;58(1):15-9.

PMID:
10343535
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Quadriceps weakness in knee osteoarthritis: the effect on pain and disability.

O'Reilly SC, Jones A, Muir KR, Doherty M.

Ann Rheum Dis. 1998 Oct;57(10):588-94.

PMID:
9893569
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Knee pain and disability in the Nottingham community: association with poor health status and psychological distress.

O'Reilly SC, Muir KR, Doherty M.

Br J Rheumatol. 1998 Aug;37(8):870-3.

PMID:
9734678
[PubMed - indexed for MEDLINE]
Free Article

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