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Results: 1 to 20 of 163


Carboplatin and taxol resistance develops more rapidly in functional BRCA1 compared to dysfunctional BRCA1 ovarian cancer cells.

Busschots S, O'Toole S, O'Leary JJ, Stordal B.

Exp Cell Res. 2014 Dec 12. pii: S0014-4827(14)00527-8. doi: 10.1016/j.yexcr.2014.12.001. [Epub ahead of print]


Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention.

Ffrench B, Gasch C, O'Leary JJ, Gallagher MF.

Mol Cancer. 2014 Dec 11;13:262. doi: 10.1186/1476-4598-13-262.


Raman microspectroscopy for the early detection of pre-malignant changes in cervical tissue.

Rashid N, Nawaz H, Poon KW, Bonnier F, Bakhiet S, Martin C, O'Leary JJ, Byrne HJ, Lyng FM.

Exp Mol Pathol. 2014 Dec;97(3):554-64. doi: 10.1016/j.yexmp.2014.10.013. Epub 2014 Nov 3.


The use of MYBL2 as a novel candidate biomarker of cervical cancer.

Martin CM, Astbury K, Kehoe L, O'Crowley JB, O'Toole S, O'Leary JJ.

Methods Mol Biol. 2015;1249:241-51. doi: 10.1007/978-1-4939-2013-6_18.


Human papillomavirus DNA and mRNA prevalence and association with cervical cytological abnormalities in the Irish HIV population.

Loy A, McInerney J, Pilkington L, Keegan H, Delamere S, Martin CM, Sheils O, O'Leary JJ, Mulcahy F.

Int J STD AIDS. 2014 Sep 25. pii: 0956462414553454. [Epub ahead of print]


Influences on human papillomavirus (HPV)-related information needs among women having HPV tests for follow-up of abnormal cervical cytology.

O'Connor M, Costello L, Murphy J, Prendiville W, Martin CM, O'Leary JJ, Sharp L; Irish Screening Research Consortium (CERVIVA).

J Fam Plann Reprod Health Care. 2015 Apr;41(2):134-41. doi: 10.1136/jfprhc-2013-100750. Epub 2014 Sep 23.


An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines.

Vencken SF, Sethupathy P, Blackshields G, Spillane C, Elbaruni S, Sheils O, Gallagher MF, O'Leary JJ.

BMC Genomics. 2014 Aug 25;15:711. doi: 10.1186/1471-2164-15-711.


The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.

d'Adhemar CJ, Spillane CD, Gallagher MF, Bates M, Costello KM, Barry-O'Crowley J, Haley K, Kernan N, Murphy C, Smyth PC, O'Byrne K, Pennington S, Cooke AA, Ffrench B, Martin CM, O'Donnell D, Hennessy B, Stordal B, Finn S, McCann A, Gleeson N, D'Arcy T, Flood B, O'Neill LA, Sheils O, O'Toole S, O'Leary JJ.

PLoS One. 2014 Jun 30;9(6):e100816. doi: 10.1371/journal.pone.0100816. eCollection 2014. Erratum in: PLoS One. 2014;9(9):e108833.


Role of human papillomavirus in oropharyngeal squamous cell carcinoma: A review.

Woods R Sr, O'Regan EM, Kennedy S, Martin C, O'Leary JJ, Timon C.

World J Clin Cases. 2014 Jun 16;2(6):172-93. doi: 10.12998/wjcc.v2.i6.172. Review.


PARP Inhibitors as P-glyoprotein Substrates.

Lawlor D, Martin P, Busschots S, Thery J, O'Leary JJ, Hennessy BT, Stordal B.

J Pharm Sci. 2014 Jun;103(6):1913-20. doi: 10.1002/jps.23952. Epub 2014 Apr 3.


'I don't care whether it's HPV or ABC, I just want to know if I have cancer.' Factors influencing women's emotional responses to undergoing human papillomavirus testing in routine management in cervical screening: a qualitative study.

O'Connor M, Costello L, Murphy J, Prendiville W, Martin CM, O'Leary JJ, Sharp L; Irish Screening Research Consortium (CERVIVA).

BJOG. 2014 Oct;121(11):1421-9. doi: 10.1111/1471-0528.12741. Epub 2014 Apr 1.


Molecular testing in oncology: problems, pitfalls and progress.

O'Brien CP, Taylor SE, O'Leary JJ, Finn SP.

Lung Cancer. 2014 Mar;83(3):309-15. doi: 10.1016/j.lungcan.2013.12.010. Epub 2014 Jan 3. Review.


Collateral sensitivity to cisplatin in KB-8-5-11 drug-resistant cancer cells.

Doherty B, Lawlor D, Gillet JP, Gottesman M, O'Leary JJ, Stordal B.

Anticancer Res. 2014 Jan;34(1):503-7.


Predictive values for molecular diagnostics: converting unknown unknowns to known unknowns.

O'Brien CP, Langabeer SE, O'Byrne KJ, O'Leary JJ, Finn SP.

Mol Diagn Ther. 2014 Feb;18(1):1-4. doi: 10.1007/s40291-013-0076-x. No abstract available.


Estrogen receptor alpha augments changes in hemostatic gene expression in HepG2 cells treated with estradiol and phytoestrogens.

Kelly LA, Seidlova-Wuttke D, Wuttke W, O'Leary JJ, Norris LA.

Phytomedicine. 2014 Jan 15;21(2):155-8. doi: 10.1016/j.phymed.2013.07.012. Epub 2013 Aug 23.


Evaluation of the clinical performance of the cobas 4800 HPV test in patients referred for colposcopy.

White C, Keegan H, Pilkington L, Ruttle C, Kerr P, Sharp L, O'Toole S, Turner M, Prendiville W, D'Arcy T, Fitzpatrick M, Lenehan P, Flannelly G, O'Leary JJ, Martin CM.

J Clin Microbiol. 2013 Oct;51(10):3415-7. doi: 10.1128/JCM.01949-13. Epub 2013 Jul 31.


BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionally deleterious BRCA1 mutation.

Stordal B, Timms K, Farrelly A, Gallagher D, Busschots S, Renaud M, Thery J, Williams D, Potter J, Tran T, Korpanty G, Cremona M, Carey M, Li J, Li Y, Aslan O, O'Leary JJ, Mills GB, Hennessy BT.

Mol Oncol. 2013 Jun;7(3):567-79. doi: 10.1016/j.molonc.2012.12.007. Epub 2013 Jan 31.


Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature.

Barr MP, Gray SG, Hoffmann AC, Hilger RA, Thomale J, O'Flaherty JD, Fennell DA, Richard D, O'Leary JJ, O'Byrne KJ.

PLoS One. 2013;8(1):e54193. doi: 10.1371/journal.pone.0054193. Epub 2013 Jan 17.


Pre-Treatment of Platinum Resistant Ovarian Cancer Cells with an MMP-9/MMP-2 Inhibitor Prior to Cisplatin Enhances Cytotoxicity as Determined by High Content Screening.

Laios A, Mohamed BM, Kelly L, Flavin R, Finn S, McEvoy L, Gallagher M, Martin C, Sheils O, Ring M, Davies A, Lawson M, Gleeson N, D'Arcy T, d'Adhemar C, Norris L, Langhe R, Saadeh FA, O'Leary JJ, O'Toole SA.

Int J Mol Sci. 2013 Jan 22;14(1):2085-103. doi: 10.3390/ijms14012085.


Norethisterone acetate alters coagulation gene expression in vitro in human cell culture.

Brosnan JF, Sheppard BL, Kelly LA, O'Leary JJ, Norris LA.

Thromb Res. 2013 Jan;131(1):72-7. doi: 10.1016/j.thromres.2012.09.006. Epub 2012 Sep 19.

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