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An evaluation of the DEXLIFE 'self-selected' lifestyle intervention aimed at improving insulin sensitivity in people at risk of developing type 2 diabetes: study protocol for a randomised controlled trial.

O'Donoghue GM, Kennedy A, Andersen GS, Durkan E, Thybo T, Sinnott M, Nolan JJ, O'Gorman DJ.

Trials. 2015 Nov 18;16:529. doi: 10.1186/s13063-015-1042-1.


Modified Active Videogame Play Results in Moderate-Intensity Exercise.

Monedero J, McDonnell AC, Keoghan M, O'Gorman DJ.

Games Health J. 2014 Aug;3(4):234-40. doi: 10.1089/g4h.2013.0096. Epub 2014 May 13.


The Effects of Atorvastatin on Arterial Stiffness in Male Patients with Type 2 Diabetes.

Davenport C, Ashley DT, O'Sullivan EP, McHenry CM, Agha A, Thompson CJ, O'Gorman DJ, Smith D.

J Diabetes Res. 2015;2015:846807. doi: 10.1155/2015/846807. Epub 2015 Apr 30.


Higher rate of fat oxidation during rowing compared with cycling ergometer exercise across a range of exercise intensities.

Egan B, Ashley DT, Kennedy E, O'Connor PL, O'Gorman DJ.

Scand J Med Sci Sports. 2016 Jun;26(6):630-7. doi: 10.1111/sms.12498. Epub 2015 Jun 9.


Interactive video game cycling leads to higher energy expenditure and is more enjoyable than conventional exercise in adults.

Monedero J, Lyons EJ, O'Gorman DJ.

PLoS One. 2015 Mar 4;10(3):e0118470. doi: 10.1371/journal.pone.0118470. eCollection 2015.


The DEXLIFE study methods: identifying novel candidate biomarkers that predict progression to type 2 diabetes in high risk individuals.

Andersen GS, Thybo T, Cederberg H, Orešič M, Esteller M, Zorzano A, Carr B, Walker M, Cobb J, Clissmann C, O'Gorman DJ, Nolan JJ; DEXLIFE Consortium.

Diabetes Res Clin Pract. 2014 Nov;106(2):383-9. doi: 10.1016/j.diabres.2014.07.025. Epub 2014 Jul 27.


Towards the integration and development of a cross-European research network and infrastructure: the DEterminants of DIet and Physical ACtivity (DEDIPAC) Knowledge Hub.

Lakerveld J, van der Ploeg HP, Kroeze W, Ahrens W, Allais O, Andersen LF, Cardon G, Capranica L, Chastin S, Donnelly A, Ekelund U, Finglas P, Flechtner-Mors M, Hebestreit A, Hendriksen I, Kubiak T, Lanza M, Loyen A, MacDonncha C, Mazzocchi M, Monsivais P, Murphy M, Nöthlings U, O'Gorman DJ, Renner B, Roos G, Schuit AJ, Schulze M, Steinacker J, Stronks K, Volkert D, Van't Veer P, Lien N, De Bourdeaudhuij I, Brug J; DEDIPAC consortium.

Int J Behav Nutr Phys Act. 2014 Nov 22;11:143. doi: 10.1186/s12966-014-0143-7.


Time course analysis reveals gene-specific transcript and protein kinetics of adaptation to short-term aerobic exercise training in human skeletal muscle.

Egan B, O'Connor PL, Zierath JR, O'Gorman DJ.

PLoS One. 2013 Sep 12;8(9):e74098. doi: 10.1371/journal.pone.0074098. eCollection 2013.


Transient increase in homocysteine but not hyperhomocysteinemia during acute exercise at different intensities in sedentary individuals.

Iglesias-Gutiérrez E, Egan B, Díaz-Martínez ÁE, Peñalvo JL, González-Medina A, Martínez-Camblor P, O'Gorman DJ, Úbeda N.

PLoS One. 2012;7(12):e51185. doi: 10.1371/journal.pone.0051185. Epub 2012 Dec 7.


A comparison of osteoprotegerin with adiponectin and high-sensitivity C-reactive protein (hsCRP) as a marker for insulin resistance.

O'Sullivan EP, Ashley DT, Davenport C, Penugonda L, Kelleher G, Devlin N, Crowley R, O'Shea P, Agha A, Thompson CJ, O'Gorman DJ, Smith D.

Metabolism. 2013 Jan;62(1):34-8. doi: 10.1016/j.metabol.2012.06.005. Epub 2012 Jul 27.


The effect of exercise on osteoprotegerin and TNF-related apoptosis-inducing ligand in obese patients.

Davenport C, Kenny H, Ashley DT, O'Sullivan EP, Smith D, O'Gorman DJ.

Eur J Clin Invest. 2012 Nov;42(11):1173-9. doi: 10.1111/j.1365-2362.2012.02703.x. Epub 2012 Jul 17.


Lipoprotein particle distribution and skeletal muscle lipoprotein lipase activity after acute exercise.

Harrison M, Moyna NM, Zderic TW, O'Gorman DJ, McCaffrey N, Carson BP, Hamilton MT.

Lipids Health Dis. 2012 Jul 10;11:64. doi: 10.1186/1476-511X-11-64.


Acute exercise remodels promoter methylation in human skeletal muscle.

Barrès R, Yan J, Egan B, Treebak JT, Rasmussen M, Fritz T, Caidahl K, Krook A, O'Gorman DJ, Zierath JR.

Cell Metab. 2012 Mar 7;15(3):405-11. doi: 10.1016/j.cmet.2012.01.001.


Identifying coronary artery disease in men with type 2 diabetes: osteoprotegerin, pulse wave velocity, and other biomarkers of cardiovascular risk.

Davenport C, Ashley DT, O'Sullivan EP, Corley BT, Fitzgerald P, Agha A, Thompson CJ, O'Gorman DJ, Smith D.

J Hypertens. 2011 Dec;29(12):2469-75. doi: 10.1097/HJH.0b013e32834c1e95.


Exercise and the treatment of diabetes and obesity.

O'Gorman DJ, Krook A.

Med Clin North Am. 2011 Sep;95(5):953-69. doi: 10.1016/j.mcna.2011.06.007. Review.


2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time course-dependent remodelling in response to 14 consecutive days of endurance exercise training.

Egan B, Dowling P, O'Connor PL, Henry M, Meleady P, Zierath JR, O'Gorman DJ.

Proteomics. 2011 Apr;11(8):1413-28. doi: 10.1002/pmic.201000597. Epub 2011 Feb 25.


Similar to adiponectin, serum levels of osteoprotegerin are associated with obesity in healthy subjects.

Ashley DT, O'Sullivan EP, Davenport C, Devlin N, Crowley RK, McCaffrey N, Moyna NM, Smith D, O'Gorman DJ.

Metabolism. 2011 Jul;60(7):994-1000. doi: 10.1016/j.metabol.2010.10.001. Epub 2010 Nov 18.


Osteoprotegerin is higher in peripheral arterial disease regardless of glycaemic status.

O'Sullivan EP, Ashley DT, Davenport C, Kelly J, Devlin N, Crowley R, Leahy AL, Kelly CJ, Agha A, Thompson CJ, O'Gorman DJ, Fitzgerald P, Smith D.

Thromb Res. 2010 Dec;126(6):e423-7. doi: 10.1016/j.thromres.2010.09.003. Epub 2010 Oct 6.


Effects of preoperative neuromuscular electrical stimulation on quadriceps strength and functional recovery in total knee arthroplasty. A pilot study.

Walls RJ, McHugh G, O'Gorman DJ, Moyna NM, O'Byrne JM.

BMC Musculoskelet Disord. 2010 Jun 14;11:119. doi: 10.1186/1471-2474-11-119.


Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor coactivator-1 mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle.

Egan B, Carson BP, Garcia-Roves PM, Chibalin AV, Sarsfield FM, Barron N, McCaffrey N, Moyna NM, Zierath JR, O'Gorman DJ.

J Physiol. 2010 May 15;588(Pt 10):1779-90. doi: 10.1113/jphysiol.2010.188011. Epub 2010 Mar 22.

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