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A KCNJ10 mutation previously identified in the Russell group of terriers also occurs in Smooth-Haired Fox Terriers with hereditary ataxia and in related breeds.

Rohdin C, Gilliam D, O'Leary CA, O'Brien DP, Coates JR, Johnson GS, Jäderlund KH.

Acta Vet Scand. 2015 May 23;57:26. doi: 10.1186/s13028-015-0115-1.


Pre-emptive steroids for a severe oedematous Buruli ulcer lesion: a case report.

O'Brien DP, Huffam S.

J Med Case Rep. 2015 May 1;9:98. doi: 10.1186/s13256-015-0584-x.


Understanding genetics: why should vets care?

Jones BR, Little S, Lyons LA, Malik R, Nicholas F, O'Brien DP, Pedersen NC.

J Feline Med Surg. 2015 Mar;17(3):201-2. doi: 10.1177/1098612X15571877. No abstract available.


Mycobacterium ulcerans treatment--can antibiotic duration be reduced in selected patients?

Cowan R, Athan E, Friedman ND, Hughes AJ, McDonald A, Callan P, Fyfe J, O'Brien DP.

PLoS Negl Trop Dis. 2015 Feb 6;9(2):e0003503. doi: 10.1371/journal.pntd.0003503. eCollection 2015 Feb.


A rare homozygous MFSD8 single-base-pair deletion and frameshift in the whole genome sequence of a Chinese Crested dog with neuronal ceroid lipofuscinosis.

Guo J, O'Brien DP, Mhlanga-Mutangadura T, Olby NJ, Taylor JF, Schnabel RD, Katz ML, Johnson GS.

BMC Vet Res. 2015 Jan 3;10:960. doi: 10.1186/s12917-014-0181-z.


A novel mutation in CLCN1 associated with feline myotonia congenita.

Gandolfi B, Daniel RJ, O'Brien DP, Guo LT, Youngs MD, Leach SB, Jones BR, Shelton GD, Lyons LA.

PLoS One. 2014 Oct 30;9(10):e109926. doi: 10.1371/journal.pone.0109926. eCollection 2014.


Clinical features and management of a severe paradoxical reaction associated with combined treatment of Buruli ulcer and HIV co-infection.

Wanda F, Nkemenang P, Ehounou G, Tchaton M, Comte E, Toutous Trellu L, Masouyé I, Christinet V, O'Brien DP.

BMC Infect Dis. 2014 Jul 30;14:423. doi: 10.1186/1471-2334-14-423.


Moxifloxacin for Buruli ulcer/HIV-coinfected patients: kill two birds with one stone? Author reply.

O'Brien DP, Comte E, Ford N, Christinet V, Du Cros P.

AIDS. 2014 Jul 31;28(12):1845-6. doi: 10.1097/QAD.0000000000000304. No abstract available.


DNA testing in neurologic diseases.

O'Brien DP, Leeb T.

J Vet Intern Med. 2014 Jul-Aug;28(4):1186-98. doi: 10.1111/jvim.12383. Epub 2014 Jun 24.


A CLN8 nonsense mutation in the whole genome sequence of a mixed breed dog with neuronal ceroid lipofuscinosis and Australian Shepherd ancestry.

Guo J, Johnson GS, Brown HA, Provencher ML, da Costa RC, Mhlanga-Mutangadura T, Taylor JF, Schnabel RD, O'Brien DP, Katz ML.

Mol Genet Metab. 2014 Aug;112(4):302-9. doi: 10.1016/j.ymgme.2014.05.014. Epub 2014 Jun 4.


Management of BU-HIV co-infection.

O'Brien DP, Ford N, Vitoria M, Christinet V, Comte E, Calmy A, Stienstra Y, Eholie S, Asiedu K.

Trop Med Int Health. 2014 Sep;19(9):1040-7. doi: 10.1111/tmi.12342. Epub 2014 Jun 20. Review.


Serum CA19-9 is significantly upregulated up to 2 years before diagnosis with pancreatic cancer: implications for early disease detection.

O'Brien DP, Sandanayake NS, Jenkinson C, Gentry-Maharaj A, Apostolidou S, Fourkala EO, Camuzeaux S, Blyuss O, Gunu R, Dawnay A, Zaikin A, Smith RC, Jacobs IJ, Menon U, Costello E, Pereira SP, Timms JF.

Clin Cancer Res. 2015 Feb 1;21(3):622-31. doi: 10.1158/1078-0432.CCR-14-0365. Epub 2014 Jun 17.


Employing TMT quantification in a shotgun-MS platform.

O'Brien DP, Timms JF.

Methods Mol Biol. 2014;1156:187-99. doi: 10.1007/978-1-4939-0685-7_12.


Does Inherency Have a Place in Determinations of Obviousness?

O'Brien DP, Spruill WM.

Biotechnol Law Rep. 2013 Apr;32(1-2):3-16. No abstract available.


A homozygous KCNJ10 mutation in Jack Russell Terriers and related breeds with spinocerebellar ataxia with myokymia, seizures, or both.

Gilliam D, O'Brien DP, Coates JR, Johnson GS, Johnson GC, Mhlanga-Mutangadura T, Hansen L, Taylor JF, Schnabel RD.

J Vet Intern Med. 2014 May-Jun;28(3):871-7. doi: 10.1111/jvim.12355. Epub 2014 Apr 7.


Highly siderophile elements in Earth's mantle as a clock for the Moon-forming impact.

Jacobson SA, Morbidelli A, Raymond SN, O'Brien DP, Walsh KJ, Rubie DC.

Nature. 2014 Apr 3;508(7494):84-7. doi: 10.1038/nature13172.


Treatment and prevention of Mycobacterium ulcerans infection (Buruli ulcer) in Australia: guideline update.

O'Brien DP, Jenkin G, Buntine J, Steffen CM, McDonald A, Horne S, Friedman ND, Athan E, Hughes A, Callan PP, Johnson PD.

Med J Aust. 2014 Mar 17;200(5):267-70.


Breed distribution of SOD1 alleles previously associated with canine degenerative myelopathy.

Zeng R, Coates JR, Johnson GC, Hansen L, Awano T, Kolicheski A, Ivansson E, Perloski M, Lindblad-Toh K, O'Brien DP, Guo J, Katz ML, Johnson GS.

J Vet Intern Med. 2014 Mar-Apr;28(2):515-21. doi: 10.1111/jvim.12317. Epub 2014 Feb 13.


Canine hereditary ataxia in old english sheepdogs and gordon setters is associated with a defect in the autophagy gene encoding RAB24.

Agler C, Nielsen DM, Urkasemsin G, Singleton A, Tonomura N, Sigurdsson S, Tang R, Linder K, Arepalli S, Hernandez D, Lindblad-Toh K, van de Leemput J, Motsinger-Reif A, O'Brien DP, Bell J, Harris T, Steinberg S, Olby NJ.

PLoS Genet. 2014 Feb 6;10(2):e1003991. doi: 10.1371/journal.pgen.1003991. eCollection 2014 Feb.


Risk factors for recurrent Mycobacterium ulcerans disease after exclusive surgical treatment in an Australian cohort.

O'Brien DP, McDonald A, Callan P.

Med J Aust. 2014 Feb 3;200(2):86. No abstract available.

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