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IFI27 Is a Useful Genetic Marker for Diagnosis of Immunoglobulin A Nephropathy and Membranous Nephropathy Using Peripheral Blood.

Nagasawa Y, Okuzaki D, Muso E, Yamamoto R, Shinzawa M, Iwasaki Y, Iwatani H, Nakanishi T, Isaka Y, Nojima H.

PLoS One. 2016 Apr 21;11(4):e0153252. doi: 10.1371/journal.pone.0153252. eCollection 2016.


Interleukin-18-deficient mice develop dyslipidemia resulting in nonalcoholic fatty liver disease and steatohepatitis.

Yamanishi K, Maeda S, Kuwahara-Otani S, Watanabe Y, Yoshida M, Ikubo K, Okuzaki D, El-Darawish Y, Li W, Nakasho K, Nojima H, Yamanishi H, Hayakawa T, Okamura H, Matsunaga H.

Transl Res. 2016 Mar 19. pii: S1931-5244(16)00102-X. doi: 10.1016/j.trsl.2016.03.010. [Epub ahead of print]


Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase.

Wang Z, Tacchelly-Benites O, Yang E, Thorne CA, Nojima H, Lee E, Ahmed Y.

Genetics. 2016 Mar 14. pii: genetics.115.183244. [Epub ahead of print]


Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network.

Anvarian Z, Nojima H, van Kappel EC, Madl T, Spit M, Viertler M, Jordens I, Low TY, van Scherpenzeel RC, Kuper I, Richter K, Heck AJ, Boelens R, Vincent JP, Rüdiger SG, Maurice MM.

Nat Struct Mol Biol. 2016 Apr;23(4):324-32. doi: 10.1038/nsmb.3191. Epub 2016 Mar 14.


Effects of 1-cyclohexyl- and 1-cyclohexyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline on dopaminergic spontaneous discharge in nigral neurons of rats.

Abe M, Munakata H, Abe K, Saito T, Horiguchi Y, Nojima H, Taguchi K.

Brain Res Bull. 2016 Mar;121:201-8. doi: 10.1016/j.brainresbull.2016.02.007. Epub 2016 Feb 10.


[Surgical Resection for Mediastinal Lymph Node Metastasis of Combined Hepatocellular and Cholangiocarcinoma--A Case Report].

Yoshida M, Shimizu H, Ohtsuka M, Kato A, Yoshitomi H, Furukawa K, Takayashiki T, Kuboki S, Takano S, Okamura D, Suzuki D, Sakai N, Kagawa S, Nojima H, Miyazaki M.

Gan To Kagaku Ryoho. 2015 Nov;42(12):1857-9. Japanese.


[Peritoneovenous Shunting as a Palliative Therapy for Refractory Ascites after Biliary Cancer Surgery].

Miyauchi Y, Takayashiki T, Shimizu H, Ohtsuka M, Kato A, Yoshitomi H, Furukawa K, Takano S, Kuboki S, Suzuki D, Sakai N, Kagawa S, Nojima H, Miyazaki M.

Gan To Kagaku Ryoho. 2015 Nov;42(12):1550-2. Japanese.


Microarray and whole-exome sequencing analysis of familial Behçet's disease patients.

Okuzaki D, Yoshizaki K, Tanaka T, Hirano T, Fukushima K, Washio T, Nojima H.

Sci Rep. 2016 Jan 20;6:19456. doi: 10.1038/srep19456.


Cyclin G2: A novel independent prognostic marker in pancreatic cancer.

Hasegawa S, Nagano H, Konno M, Eguchi H, Tomokuni A, Tomimaru Y, Wada H, Hama N, Kawamoto K, Kobayashi S, Marubashi S, Nishida N, Koseki J, Gotoh N, Ohno S, Yabuta N, Nojima H, Mori M, Doki Y, Ishii H.

Oncol Lett. 2015 Nov;10(5):2986-2990. Epub 2015 Sep 2.


[III. Repeat pancreatectomy for recurrent pancreatic cancer].

Yoshitomi H, Shimizu H, Ohtsuka M, Kato A, Furukawa K, Takayashiki T, Kuboki S, Takano S, Suzuki D, Sakai N, Kagawa S, Nojima H, Miyazaki M.

Gan To Kagaku Ryoho. 2015 Oct;42(10):1173-7. Japanese. No abstract available.


Lats1 suppresses centrosome overduplication by modulating the stability of Cdc25B.

Mukai S, Yabuta N, Yoshida K, Okamoto A, Miura D, Furuta Y, Abe T, Nojima H.

Sci Rep. 2015 Nov 4;5:16173. doi: 10.1038/srep16173.


Effects of low-fat diet and aging on metabolic profiles of Creb3l4 knockout mice.

Kim TH, Park JM, Jo SH, Kim MY, Nojima H, Ahn YH.

Nutr Diabetes. 2015 Aug 24;5:e179. doi: 10.1038/nutd.2015.29.


Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate.

Nojima H, Freeman CM, Schuster RM, Japtok L, Kleuser B, Edwards MJ, Gulbins E, Lentsch AB.

J Hepatol. 2016 Jan;64(1):60-8. doi: 10.1016/j.jhep.2015.07.030. Epub 2015 Aug 5.


Withaferin A Induces Cell Death Selectively in Androgen-Independent Prostate Cancer Cells but Not in Normal Fibroblast Cells.

Nishikawa Y, Okuzaki D, Fukushima K, Mukai S, Ohno S, Ozaki Y, Yabuta N, Nojima H.

PLoS One. 2015 Jul 31;10(7):e0134137. doi: 10.1371/journal.pone.0134137. eCollection 2015.


Genetic analysis of genes causing hypertension and stroke in spontaneously hypertensive rats: Gene expression profiles in the kidneys.

Watanabe Y, Yoshida M, Yamanishi K, Yamamoto H, Okuzaki D, Nojima H, Yasunaga T, Okamura H, Matsunaga H, Yamanishi H.

Int J Mol Med. 2015 Sep;36(3):712-24. doi: 10.3892/ijmm.2015.2281. Epub 2015 Jul 10.


Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP.

Chen Q, Zhang N, Xie R, Wang W, Cai J, Choi KS, David KK, Huang B, Yabuta N, Nojima H, Anders RA, Pan D.

Genes Dev. 2015 Jun 15;29(12):1285-97. doi: 10.1101/gad.264234.115.


Additional donepezil treatment for patients with geriatric depression who exhibit cognitive deficit during treatment for depression.

Inoue J, Hoshino R, Nojima H, Ishida W, Okamoto N.

Psychogeriatrics. 2016 Jan;16(1):54-61. doi: 10.1111/psyg.12121. Epub 2015 Apr 27.


ELAS1-mediated inhibition of the cyclin G1-B'γ interaction promotes cancer cell apoptosis via stabilization and activation of p53.

Ohno S, Naito Y, Mukai S, Yabuta N, Nojima H.

Oncogene. 2015 Dec 3;34(49):5983-96. doi: 10.1038/onc.2015.47. Epub 2015 Apr 27.


Phosphorylation of CHO1 by Lats1/2 regulates the centrosomal activation of LIMK1 during cytokinesis.

Okamoto A, Yabuta N, Mukai S, Torigata K, Nojima H.

Cell Cycle. 2015;14(10):1568-82. doi: 10.1080/15384101.2015.1026489.


Sphingolipids in liver injury, repair and regeneration.

Nojima H, Freeman CM, Gulbins E, Lentsch AB.

Biol Chem. 2015 Jun;396(6-7):633-43. doi: 10.1515/hsz-2014-0296. Review.

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