Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 1 to 20 of 57

1.

Identification of small-molecule compounds targeting the dishevelled PDZ domain by virtual screening and binding studies.

Choi J, Ma S, Kim HY, Yun JH, Heo JN, Lee W, Choi KY, No KT.

Bioorg Med Chem. 2016 Mar 16. pii: S0968-0896(16)30175-4. doi: 10.1016/j.bmc.2016.03.026. [Epub ahead of print]

PMID:
27112452
2.

Small molecule inhibitors of the Dishevelled-CXXC5 interaction are new drug candidates for bone anabolic osteoporosis therapy.

Kim HY, Choi S, Yoon JH, Lim HJ, Lee H, Choi J, Ro EJ, Heo JN, Lee W, No KT, Choi KY.

EMBO Mol Med. 2016 Mar 2. pii: e201505714. doi: 10.15252/emmm.201505714. [Epub ahead of print]

3.

Identification of a Small Benzamide Inhibitor of Influenza Virus Using a Cell-Based Screening.

Shin WJ, Nam KY, Kim ND, Kim SH, No KT, Seong BL.

Chemotherapy. 2016;61(3):159-66. doi: 10.1159/000441941. Epub 2016 Jan 29.

PMID:
26821172
4.

Inhibition of cancer cell invasion by new ((3,4-dihydroxy benzylidene)hydrazinyl)pyridine-3-sulfonamide analogs.

Kang SM, Nam KY, Jung SY, Song KH, Kho S, No KT, Choi HK, Song JY.

Bioorg Med Chem Lett. 2016 Feb 15;26(4):1322-8. doi: 10.1016/j.bmcl.2015.12.093. Epub 2015 Dec 29.

PMID:
26810259
5.

Discovery of 2-aryloxy-4-amino-quinazoline derivatives as novel protease-activated receptor 2 (PAR2) antagonists.

Cho NC, Cha JH, Kim H, Kwak J, Kim D, Seo SH, Shin JS, Kim T, Park KD, Lee J, No KT, Kim YK, Lee KT, Pae AN.

Bioorg Med Chem. 2015 Dec 15;23(24):7717-27. doi: 10.1016/j.bmc.2015.11.016. Epub 2015 Nov 18.

PMID:
26631441
6.

Discovery of Novel Anti-prion Compounds Using In Silico and In Vitro Approaches.

Hyeon JW, Choi J, Kim SY, Govindaraj RG, Jam Hwang K, Lee YS, An SS, Lee MK, Joung JY, No KT, Lee J.

Sci Rep. 2015 Oct 9;5:14944. doi: 10.1038/srep14944.

7.

Novel Scaffold Identification of mGlu1 Receptor Negative Allosteric Modulators Using a Hierarchical Virtual Screening Approach.

Jang JW, Cho NC, Min SJ, Cho YS, Park KD, Seo SH, No KT, Pae AN.

Chem Biol Drug Des. 2016 Feb;87(2):239-56. doi: 10.1111/cbdd.12654. Epub 2015 Oct 9.

PMID:
26343933
8.

Computational classification models for predicting the interaction of compounds with hepatic organic ion importers.

You H, Lee K, Lee S, Hwang SB, Kim KY, Cho KH, No KT.

Drug Metab Pharmacokinet. 2015 Oct;30(5):347-51. doi: 10.1016/j.dmpk.2015.06.004. Epub 2015 Jun 26.

PMID:
26293543
9.

Assessment of quantitative structure-activity relationship of toxicity prediction models for Korean chemical substance control legislation.

Kim KY, Shin SE, No KT.

Environ Health Toxicol. 2015 Jun 12;30 Suppl:s2015007. doi: 10.5620/eht.s2015007. eCollection 2015.

10.

The natural phytochemical dehydroabietic acid is an anti-aging reagent that mediates the direct activation of SIRT1.

Kim J, Kang YG, Lee JY, Choi DH, Cho YU, Shin JM, Park JS, Lee JH, Kim WG, Seo DB, Lee TR, Miyamoto Y, No KT.

Mol Cell Endocrinol. 2015 Sep 5;412:216-25. doi: 10.1016/j.mce.2015.05.006. Epub 2015 May 11.

PMID:
25976661
11.

CXXC5 is a negative-feedback regulator of the Wnt/β-catenin pathway involved in osteoblast differentiation.

Kim HY, Yoon JY, Yun JH, Cho KW, Lee SH, Rhee YM, Jung HS, Lim HJ, Lee H, Choi J, Heo JN, Lee W, No KT, Min D, Choi KY.

Cell Death Differ. 2015 Jun;22(6):912-20. doi: 10.1038/cdd.2014.238. Epub 2015 Jan 30.

PMID:
25633194
12.

Discovery of (E)-5-(benzylideneamino)-1H-benzo[d]imidazol-2(3H)-one derivatives as inhibitors for PTK6.

Shim HJ, Yang HR, Kim HIe, Kang SA, No KT, Jung YH, Lee ST.

Bioorg Med Chem Lett. 2014 Oct 1;24(19):4659-63. doi: 10.1016/j.bmcl.2014.08.036. Epub 2014 Aug 23.

PMID:
25205190
13.

An empirical model for gas phase acidity and basicity estimation.

You H, Kim GE, Na CH, Lee S, Lee CJ, Cho KH, Akiyama Y, Ishida T, No KT.

SAR QSAR Environ Res. 2014;25(2):91-115. doi: 10.1080/1062936X.2013.864997. Epub 2014 Mar 5.

PMID:
24597990
14.

Identification of novel rab27a/melanophilin blockers by pharmacophore-based virtual screening.

Joung JY, Lee HY, Park J, Lee JY, Chang BH, No KT, Nam KY, Hwang JS.

Appl Biochem Biotechnol. 2014 Feb;172(4):1882-97. doi: 10.1007/s12010-013-0615-2. Epub 2013 Nov 30.

PMID:
24293275
15.

Human nephrotoxicity prediction models for three types of kidney injury based on data sets of pharmacological compounds and their metabolites.

Lee S, Kang YM, Park H, Dong MS, Shin JM, No KT.

Chem Res Toxicol. 2013 Nov 18;26(11):1652-9. doi: 10.1021/tx400249t. Epub 2013 Nov 5.

PMID:
24138086
16.

A generalized G-SFED continuum solvation free energy calculation model.

Lee S, Cho KH, Kang YM, Scheraga HA, No KT.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E662-7. doi: 10.1073/pnas.1221940110. Epub 2013 Feb 1.

17.

Structure-based design and synthesis of C-1- and C-4-modified analogs of zanamivir as neuraminidase inhibitors.

Feng E, Shin WJ, Zhu X, Li J, Ye D, Wang J, Zheng M, Zuo JP, No KT, Liu X, Zhu W, Tang W, Seong BL, Jiang H, Liu H.

J Med Chem. 2013 Feb 14;56(3):671-84. doi: 10.1021/jm3009713. Epub 2013 Jan 30.

PMID:
23330908
18.

Synthesis of C-4-modified zanamivir analogs as neuraminidase inhibitors and their anti-AIV activities.

Ye D, Shin WJ, Li N, Tang W, Feng E, Li J, He PL, Zuo JP, Kim H, Nam KY, Zhu W, Seong BL, No KT, Jiang H, Liu H.

Eur J Med Chem. 2012 Aug;54:764-70. doi: 10.1016/j.ejmech.2012.06.033. Epub 2012 Jun 29.

PMID:
22795831
19.

PXR ligand classification model with SFED-weighted WHIM and CoMMA descriptors.

Ma SL, Joung JY, Lee S, Cho KH, No KT.

SAR QSAR Environ Res. 2012 Jul;23(5-6):485-504. doi: 10.1080/1062936X.2012.665385. Epub 2012 May 16.

PMID:
22591167
20.

Hypnotic effects and GABAergic mechanism of licorice (Glycyrrhiza glabra) ethanol extract and its major flavonoid constituent glabrol.

Cho S, Park JH, Pae AN, Han D, Kim D, Cho NC, No KT, Yang H, Yoon M, Lee C, Shimizu M, Baek NI.

Bioorg Med Chem. 2012 Jun 1;20(11):3493-501. doi: 10.1016/j.bmc.2012.04.011. Epub 2012 Apr 11.

PMID:
22543233
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk