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Results: 1 to 20 of 126

1.

A genome scale overexpression screen to reveal drug activity in human cells.

Arnoldo A, Kittanakom S, Heisler LE, Mak AB, Shukalyuk AI, Torti D, Moffat J, Giaever G, Nislow C.

Genome Med. 2014 Apr 29;6(4):32. doi: 10.1186/gm549. eCollection 2014.

PMID:
24944581
[PubMed]
Free PMC Article
2.

The Yeast Deletion Collection: A Decade of Functional Genomics.

Giaever G, Nislow C.

Genetics. 2014 Jun 17;197(2):451-465. [Epub ahead of print]

PMID:
24939991
[PubMed - as supplied by publisher]
Free PMC Article
3.

Mapping the cellular response to small molecules using chemogenomic fitness signatures.

Lee AY, St Onge RP, Proctor MJ, Wallace IM, Nile AH, Spagnuolo PA, Jitkova Y, Gronda M, Wu Y, Kim MK, Cheung-Ong K, Torres NP, Spear ED, Han MK, Schlecht U, Suresh S, Duby G, Heisler LE, Surendra A, Fung E, Urbanus ML, Gebbia M, Lissina E, Miranda M, Chiang JH, Aparicio AM, Zeghouf M, Davis RW, Cherfils J, Boutry M, Kaiser CA, Cummins CL, Trimble WS, Brown GW, Schimmer AD, Bankaitis VA, Nislow C, Bader GD, Giaever G.

Science. 2014 Apr 11;344(6180):208-11. doi: 10.1126/science.1250217. Erratum in: Science. 2014 May 23;344(6186):1255771.

PMID:
24723613
[PubMed - indexed for MEDLINE]
4.

Broad metabolic sensitivity profiling of a prototrophic yeast deletion collection.

VanderSluis B, Hess DC, Pesyna C, Krumholz EW, Syed T, Szappanos B, Nislow C, Papp B, Troyanskaya OG, Myers CL, Caudy AA.

Genome Biol. 2014 Apr 10;15(4):R64. doi: 10.1186/gb-2014-15-4-r64.

PMID:
24721214
[PubMed - in process]
Free PMC Article
5.

Large-scale identification and analysis of suppressive drug interactions.

Cokol M, Weinstein ZB, Yilancioglu K, Tasan M, Doak A, Cansever D, Mutlu B, Li S, Rodriguez-Esteban R, Akhmedov M, Guvenek A, Cokol M, Cetiner S, Giaever G, Iossifov I, Nislow C, Shoichet B, Roth FP.

Chem Biol. 2014 Apr 24;21(4):541-51. doi: 10.1016/j.chembiol.2014.02.012. Epub 2014 Apr 3.

PMID:
24704506
[PubMed - in process]
6.

GC-rich DNA elements enable replication origin activity in the methylotrophic yeast Pichia pastoris.

Liachko I, Youngblood RA, Tsui K, Bubb KL, Queitsch C, Raghuraman MK, Nislow C, Brewer BJ, Dunham MJ.

PLoS Genet. 2014 Mar 6;10(3):e1004169. doi: 10.1371/journal.pgen.1004169. eCollection 2014 Mar.

PMID:
24603708
[PubMed - in process]
Free PMC Article
7.

CHIP-MYTH: a novel interactive proteomics method for the assessment of agonist-dependent interactions of the human β₂-adrenergic receptor.

Kittanakom S, Barrios-Rodiles M, Petschnigg J, Arnoldo A, Wong V, Kotlyar M, Heisler LE, Jurisica I, Wrana JL, Nislow C, Stagljar I.

Biochem Biophys Res Commun. 2014 Mar 21;445(4):746-56. doi: 10.1016/j.bbrc.2014.02.033. Epub 2014 Feb 19.

PMID:
24561123
[PubMed - indexed for MEDLINE]
8.

Sequencing and functional analysis of the genome of a nematode egg-parasitic fungus, Pochonia chlamydosporia.

Larriba E, Jaime MD, Carbonell-Caballero J, Conesa A, Dopazo J, Nislow C, Martín-Nieto J, Lopez-Llorca LV.

Fungal Genet Biol. 2014 Apr;65:69-80. doi: 10.1016/j.fgb.2014.02.002. Epub 2014 Feb 13.

PMID:
24530791
[PubMed - in process]
9.

PITPs as targets for selectively interfering with phosphoinositide signaling in cells.

Nile AH, Tripathi A, Yuan P, Mousley CJ, Suresh S, Wallace IM, Shah SD, Pohlhaus DT, Temple B, Nislow C, Giaever G, Tropsha A, Davis RW, St Onge RP, Bankaitis VA.

Nat Chem Biol. 2014 Jan;10(1):76-84. doi: 10.1038/nchembio.1389. Epub 2013 Nov 24.

PMID:
24292071
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Conserved substitution patterns around nucleosome footprints in eukaryotes and Archaea derive from frequent nucleosome repositioning through evolution.

Warnecke T, Becker EA, Facciotti MT, Nislow C, Lehner B.

PLoS Comput Biol. 2013;9(11):e1003373. doi: 10.1371/journal.pcbi.1003373. Epub 2013 Nov 21.

PMID:
24278010
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A unified model for yeast transcript definition.

de Boer CG, van Bakel H, Tsui K, Li J, Morris QD, Nislow C, Greenblatt JF, Hughes TR.

Genome Res. 2014 Jan;24(1):154-66. doi: 10.1101/gr.164327.113. Epub 2013 Oct 29.

PMID:
24170600
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A novel small molecule methyltransferase is important for virulence in Candida albicans.

Lissina E, Weiss D, Young B, Rella A, Cheung-Ong K, Del Poeta M, Clarke SG, Giaever G, Nislow C.

ACS Chem Biol. 2013 Dec 20;8(12):2785-93. doi: 10.1021/cb400607h. Epub 2013 Oct 16.

PMID:
24083538
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Whole genome duplication and enrichment of metal cation transporters revealed by de novo genome sequencing of extremely halotolerant black yeast Hortaea werneckii.

Lenassi M, Gostinčar C, Jackman S, Turk M, Sadowski I, Nislow C, Jones S, Birol I, Cimerman NG, Plemenitaš A.

PLoS One. 2013 Aug 15;8(8):e71328. doi: 10.1371/journal.pone.0071328. eCollection 2013.

PMID:
23977017
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Miniature short hairpin RNA screens to characterize antiproliferative drugs.

Kittanakom S, Arnoldo A, Brown KR, Wallace I, Kunavisarut T, Torti D, Heisler LE, Surendra A, Moffat J, Giaever G, Nislow C.

G3 (Bethesda). 2013 Aug 7;3(8):1375-87. doi: 10.1534/g3.113.006437.

PMID:
23797109
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A high-throughput yeast assay identifies synergistic drug combinations.

Torres NP, Lee AY, Giaever G, Nislow C, Brown GW.

Assay Drug Dev Technol. 2013 Jun;11(5):299-307. doi: 10.1089/adt.2012.503.

PMID:
23772551
[PubMed - indexed for MEDLINE]
16.

DNA-damaging agents in cancer chemotherapy: serendipity and chemical biology.

Cheung-Ong K, Giaever G, Nislow C.

Chem Biol. 2013 May 23;20(5):648-59. doi: 10.1016/j.chembiol.2013.04.007. Review.

PMID:
23706631
[PubMed - indexed for MEDLINE]
Free Article
17.

A compendium of nucleosome and transcript profiles reveals determinants of chromatin architecture and transcription.

van Bakel H, Tsui K, Gebbia M, Mnaimneh S, Hughes TR, Nislow C.

PLoS Genet. 2013 May;9(5):e1003479. doi: 10.1371/journal.pgen.1003479. Epub 2013 May 2.

PMID:
23658529
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system.

Wan LC, Mao DY, Neculai D, Strecker J, Chiovitti D, Kurinov I, Poda G, Thevakumaran N, Yuan F, Szilard RK, Lissina E, Nislow C, Caudy AA, Durocher D, Sicheri F.

Nucleic Acids Res. 2013 Jul;41(12):6332-46. doi: 10.1093/nar/gkt322. Epub 2013 Apr 25.

PMID:
23620299
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Genetic and genomic architecture of the evolution of resistance to antifungal drug combinations.

Hill JA, Ammar R, Torti D, Nislow C, Cowen LE.

PLoS Genet. 2013 Apr;9(4):e1003390. doi: 10.1371/journal.pgen.1003390. Epub 2013 Apr 4.

PMID:
23593013
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Global analysis of SUMO chain function reveals multiple roles in chromatin regulation.

Srikumar T, Lewicki MC, Costanzo M, Tkach JM, van Bakel H, Tsui K, Johnson ES, Brown GW, Andrews BJ, Boone C, Giaever G, Nislow C, Raught B.

J Cell Biol. 2013 Apr 1;201(1):145-63. doi: 10.1083/jcb.201210019.

PMID:
23547032
[PubMed - indexed for MEDLINE]
Free PMC Article

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