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Results: 1 to 20 of 365

1.

Carboxylesterase 1 c.428G>A single nucleotide variation increases the antiplatelet effects of clopidogrel by reducing its hydrolysis in humans.

Tarkiainen EK, Holmberg MT, Tornio A, Neuvonen M, Neuvonen PJ, Backman JT, Niemi M.

Clin Pharmacol Ther. 2015 Feb 19. doi: 10.1002/cpt.101. [Epub ahead of print]

PMID:
25704243
2.

Effect of grapefruit juice on the bioactivation of prasugrel.

Holmberg MT, Tornio A, Hyvärinen H, Neuvonen M, Neuvonen PJ, Backman JT, Niemi M.

Br J Clin Pharmacol. 2014 Dec 31. doi: 10.1111/bcp.12581. [Epub ahead of print]

PMID:
25557052
3.

Ketamine coadministration attenuates morphine tolerance and leads to increased brain concentrations of both drugs in the rat.

Lilius TO, Jokinen V, Neuvonen MS, Niemi M, Kalso EA, Rauhala PV.

Br J Pharmacol. 2014 Oct 9. doi: 10.1111/bph.12974. [Epub ahead of print]

4.

Paroxetine markedly increases plasma concentrations of ophthalmic timolol; CYP2D6 inhibitors may increase the risk of cardiovascular adverse effects of 0.5% timolol eye drops.

Mäenpää J, Volotinen-Maja M, Kautiainen H, Neuvonen M, Niemi M, Neuvonen PJ, Backman JT.

Drug Metab Dispos. 2014 Dec;42(12):2068-76. doi: 10.1124/dmd.114.059576. Epub 2014 Sep 26.

PMID:
25261563
5.

Organic-inorganic azafullerene-gold C(59)N-Au nanohybrid: synthesis, characterization, and properties.

Rotas G, Niemi M, Tkachenko NV, Zhao S, Shinohara H, Tagmatarchis N.

Chemistry. 2014 Nov 3;20(45):14729-35. doi: 10.1002/chem.201403517. Epub 2014 Sep 15.

PMID:
25223388
6.

Kidney donation and risk of ESRD.

Niemi M, Mandelbrot DA.

JAMA. 2014 Jul 2;312(1):92. doi: 10.1001/jama.2014.5521. No abstract available.

PMID:
25058224
7.

Glucuronidation converts clopidogrel to a strong time-dependent inhibitor of CYP2C8: a phase II metabolite as a perpetrator of drug-drug interactions.

Tornio A, Filppula AM, Kailari O, Neuvonen M, Nyrönen TH, Tapaninen T, Neuvonen PJ, Niemi M, Backman JT.

Clin Pharmacol Ther. 2014 Oct;96(4):498-507. doi: 10.1038/clpt.2014.141. Epub 2014 Jun 27.

PMID:
24971633
8.

Association between fluid balance and survival in critically ill patients.

Lee J, de Louw E, Niemi M, Nelson R, Mark RG, Celi LA, Mukamal KJ, Danziger J.

J Intern Med. 2015 Apr;277(4):468-77. doi: 10.1111/joim.12274. Epub 2014 Jun 27.

PMID:
24931482
9.

Dry paths effectively reduce road mortality of small and medium-sized terrestrial vertebrates.

Niemi M, Jääskeläinen NC, Nummi P, Mäkelä T, Norrdahl K.

J Environ Manage. 2014 Nov 1;144:51-7. doi: 10.1016/j.jenvman.2014.05.012. Epub 2014 Jun 9.

PMID:
24921961
10.

The clinical pharmacogenetics implementation consortium guideline for SLCO1B1 and simvastatin-induced myopathy: 2014 update.

Ramsey LB, Johnson SG, Caudle KE, Haidar CE, Voora D, Wilke RA, Maxwell WD, McLeod HL, Krauss RM, Roden DM, Feng Q, Cooper-DeHoff RM, Gong L, Klein TE, Wadelius M, Niemi M.

Clin Pharmacol Ther. 2014 Oct;96(4):423-8. doi: 10.1038/clpt.2014.125. Epub 2014 Jun 11.

11.

Structural aspects of dog allergies: the crystal structure of a dog dander allergen Can f 4.

Niemi MH, Rytkönen-Nissinen M, Jänis J, Virtanen T, Rouvinen J.

Mol Immunol. 2014 Sep;61(1):7-15. doi: 10.1016/j.molimm.2014.04.003. Epub 2014 May 21.

PMID:
24859823
12.
13.

Pharmacogenetically based dosing of thiopurines in childhood acute lymphoblastic leukemia: influence on cure rates and risk of second cancer.

Levinsen M, Rotevatn EØ, Rosthøj S, Nersting J, Abrahamsson J, Appell ML, Bergan S, Bechensteen AG, Harila-Saari A, Heyman M, Jonsson OG, Maxild JB, Niemi M, Söderhäll S, Schmiegelow K; Nordic Society of Paediatric Haematology, Oncology.

Pediatr Blood Cancer. 2014 May;61(5):797-802. doi: 10.1002/pbc.24921. Epub 2014 Jan 3.

PMID:
24395436
14.

Response to letters regarding article, "Bacterial signatures in thrombus aspirates of patients with myocardial infarction".

Pessi T, Karhunen V, Karjalainen PP, Ylitalo A, Airaksinen JK, Niemi M, Pietila M, Lounatmaa K, Haapaniemi T, Lehtimäki T, Laaksonen R, Karhunen PJ, Mikkelsson J.

Circulation. 2013 Oct 8;128(15):e237-8. doi: 10.1161/CIRCULATIONAHA.113.004701. No abstract available.

15.

Grapefruit juice inhibits the metabolic activation of clopidogrel.

Holmberg MT, Tornio A, Neuvonen M, Neuvonen PJ, Backman JT, Niemi M.

Clin Pharmacol Ther. 2014 Mar;95(3):307-13. doi: 10.1038/clpt.2013.192. Epub 2013 Sep 25.

PMID:
24067745
16.

Circulating 25-hydroxyvitamin D is associated with insulin resistance cross-sectionally but not longitudinally in older adults: The Cardiovascular Health Study.

Danziger J, Biggs ML, Niemi M, Ix JH, Kizer JR, Djoussé L, de Boer IH, Siscovick DS, Kestenbaum B, Mukamal KJ.

Metabolism. 2013 Dec;62(12):1788-94. doi: 10.1016/j.metabol.2013.07.008. Epub 2013 Aug 27.

17.

PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 8.

Aquilante CL, Niemi M, Gong L, Altman RB, Klein TE.

Pharmacogenet Genomics. 2013 Dec;23(12):721-8. doi: 10.1097/FPC.0b013e3283653b27. Review. No abstract available.

18.

Supramolecular assemblies of bay-substituted perylene diimides in solution and on a solid substrate.

Sariola-Leikas E, Niemi M, Lemmetyinen H, Efimov A.

Org Biomol Chem. 2013 Oct 7;11(37):6397-406. doi: 10.1039/c3ob41058g.

PMID:
23959205
19.

Dendritic cells from Crohn's disease patients show aberrant STAT1 and STAT3 signaling.

Nieminen JK, Niemi M, Sipponen T, Salo HM, Klemetti P, Färkkilä M, Vakkila J, Vaarala O.

PLoS One. 2013 Aug 7;8(8):e70738. doi: 10.1371/journal.pone.0070738. eCollection 2013.

20.

Excited-state interaction of red and green perylene diimides with luminescent Ru(II) polypyridine complex.

Dubey RK, Niemi M, Kaunisto K, Stranius K, Efimov A, Tkachenko NV, Lemmetyinen H.

Inorg Chem. 2013 Sep 3;52(17):9761-73. doi: 10.1021/ic400474b. Epub 2013 Aug 13.

PMID:
23941685
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