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Items: 1 to 20 of 24


Divergent evolution of an atypical S-adenosyl-l-methionine-dependent monooxygenase involved in anthracycline biosynthesis.

Grocholski T, Dinis P, Niiranen L, Niemi J, Metsä-Ketelä M.

Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9866-71. doi: 10.1073/pnas.1501765112. Epub 2015 Jul 27.


Student interpretations of phylogenetic trees in an introductory biology course.

Dees J, Momsen JL, Niemi J, Montplaisir L.

CBE Life Sci Educ. 2014 Winter;13(4):666-76. doi: 10.1187/cbe.14-01-0003.


A shoe insole delivering subsensory vibratory noise improves balance and gait in healthy elderly people.

Lipsitz LA, Lough M, Niemi J, Travison T, Howlett H, Manor B.

Arch Phys Med Rehabil. 2015 Mar;96(3):432-9. doi: 10.1016/j.apmr.2014.10.004. Epub 2014 Oct 24.


A critical role for macrophages near axotomized neuronal cell bodies in stimulating nerve regeneration.

Niemi JP, DeFrancesco-Lisowitz A, Roldán-Hernández L, Lindborg JA, Mandell D, Zigmond RE.

J Neurosci. 2013 Oct 9;33(41):16236-48. doi: 10.1523/JNEUROSCI.3319-12.2013.


Structural basis for C-ribosylation in the alnumycin A biosynthetic pathway.

Oja T, Niiranen L, Sandalova T, Klika KD, Niemi J, Mäntsälä P, Schneider G, Metsä-Ketelä M.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1291-6. doi: 10.1073/pnas.1207407110. Epub 2013 Jan 7.


Baseline-dependent effect of noise-enhanced insoles on gait variability in healthy elderly walkers.

Stephen DG, Wilcox BJ, Niemi JB, Franz JR, Kerrigan D, D'Andrea SE.

Gait Posture. 2012 Jul;36(3):537-40. doi: 10.1016/j.gaitpost.2012.05.014. Epub 2012 Jun 26. Erratum in: Gait Posture. 2013 Jun;38(2):361. Franz, Jason [corrected to Franz, Jason R]; Kerrigan, D Casey [corrected to Kerrigan, Dr].


Tailoring enzymes involved in the biosynthesis of angucyclines contain latent context-dependent catalytic activities.

Patrikainen P, Kallio P, Fan K, Klika KD, Shaaban KA, Mäntsälä P, Rohr J, Yang K, Niemi J, Metsä-Ketelä M.

Chem Biol. 2012 May 25;19(5):647-55. doi: 10.1016/j.chembiol.2012.04.010.


Accelerated maximum likelihood parameter estimation for stochastic biochemical systems.

Daigle BJ Jr, Roh MK, Petzold LR, Niemi J.

BMC Bioinformatics. 2012 May 1;13:68. doi: 10.1186/1471-2105-13-68.


Biosynthetic pathway toward carbohydrate-like moieties of alnumycins contains unusual steps for C-C bond formation and cleavage.

Oja T, Klika KD, Appassamy L, Sinkkonen J, Mäntsälä P, Niemi J, Metsä-Ketelä M.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6024-9. doi: 10.1073/pnas.1201530109. Epub 2012 Apr 2.


Characterization of the two-component monooxygenase system AlnT/AlnH reveals early timing of quinone formation in alnumycin biosynthesis.

Grocholski T, Oja T, Humphrey L, Mäntsälä P, Niemi J, Metsä-Ketelä M.

J Bacteriol. 2012 Jun;194(11):2829-36. doi: 10.1128/JB.00228-12. Epub 2012 Mar 30.


Extension of the neuroprotective time window for thiazolidinediones in ischemic stroke is dependent on time of reperfusion.

Gamboa J, Blankenship DA, Niemi JP, Landreth GE, Karl M, Hilow E, Sundararajan S.

Neuroscience. 2010 Oct 27;170(3):846-57. doi: 10.1016/j.neuroscience.2010.07.063. Epub 2010 Aug 5.


Image segmentation and dynamic lineage analysis in single-cell fluorescence microscopy.

Wang Q, Niemi J, Tan CM, You L, West M.

Cytometry A. 2010 Jan;77(1):101-10. doi: 10.1002/cyto.a.20812.


Expression, purification and crystallization of the cofactor-independent monooxygenase SnoaB from the nogalamycin biosynthetic pathway.

Koskiniemi H, Grocholski T, Schneider G, Niemi J.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Mar 1;65(Pt 3):256-9. doi: 10.1107/S1744309109001389. Epub 2009 Feb 14.


Cytotype regulation by telomeric P elements in Drosophila melanogaster: interactions with P elements from M' strains.

Simmons MJ, Niemi JB, Ryzek DF, Lamour C, Goodman JW, Kraszkiewicz W, Wolff R.

Genetics. 2007 Aug;176(4):1957-66. Epub 2007 Jun 11.


RMBNToolbox: random models for biochemical networks.

Aho T, Smolander OP, Niemi J, Yli-Harja O.

BMC Syst Biol. 2007 May 24;1:22.


Aclacinomycin oxidoreductase (AknOx) from the biosynthetic pathway of the antibiotic aclacinomycin is an unusual flavoenzyme with a dual active site.

Alexeev I, Sultana A, Mäntsälä P, Niemi J, Schneider G.

Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6170-5. Epub 2007 Mar 29.


Impairment of cytotype regulation of P-element activity in Drosophila melanogaster by mutations in the Su(var)205 gene.

Haley KJ, Stuart JR, Raymond JD, Niemi JB, Simmons MJ.

Genetics. 2005 Oct;171(2):583-95. Epub 2005 Jul 5.


Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation.

Sultana A, Kallio P, Jansson A, Wang JS, Niemi J, Mäntsälä P, Schneider G.

EMBO J. 2004 May 5;23(9):1911-21. Epub 2004 Apr 8.

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