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Nontuberculous mycobacterial infections in cystic fibrosis.

Martiniano SL, Nick JA.

Clin Chest Med. 2015 Mar;36(1):101-15. doi: 10.1016/j.ccm.2014.11.003. Review.


Mycobacterium abscessus morphotype comparison in a murine model.

Caverly LJ, Caceres SM, Fratelli C, Happoldt C, Kidwell KM, Malcolm KC, Nick JA, Nichols DP.

PLoS One. 2015 Feb 12;10(2):e0117657. doi: 10.1371/journal.pone.0117657. eCollection 2015.


Pharmacokinetics and tolerability of oral sildenafil in adults with cystic fibrosis lung disease.

Taylor-Cousar JL, Wiley C, Felton LA, St Clair C, Jones M, Curran-Everett D, Poch K, Nichols DP, Solomon GM, Saavedra MT, Accurso FJ, Nick JA.

J Cyst Fibros. 2015 Mar;14(2):228-36. doi: 10.1016/j.jcf.2014.10.006. Epub 2014 Nov 13.


Endothelin-1-mediated vasoconstriction alters cerebral gene expression in iron homeostasis and eicosanoid metabolism.

Bickford JS, Ali NF, Nick JA, Al-Yahia M, Beachy DE, Doré S, Nick HS, Waters MF.

Brain Res. 2014 Nov 7;1588:25-36. doi: 10.1016/j.brainres.2014.09.022. Epub 2014 Sep 16.


Comparison of radiographic and clinical characteristics of low-risk and high-risk cystic fibrosis genotypes.

Ferril GR, Nick JA, Getz AE, Barham HP, Saavedra MT, Taylor-Cousar JL, Nichols DP, Curran-Everett D, Kingdom TT, Ramakrishnan VR.

Int Forum Allergy Rhinol. 2014 Nov;4(11):915-20. doi: 10.1002/alr.21412. Epub 2014 Sep 15.


Enhanced in vitro formation and antibiotic resistance of nonattached Pseudomonas aeruginosa aggregates through incorporation of neutrophil products.

Caceres SM, Malcolm KC, Taylor-Cousar JL, Nichols DP, Saavedra MT, Bratton DL, Moskowitz SM, Burns JL, Nick JA.

Antimicrob Agents Chemother. 2014 Nov;58(11):6851-60. doi: 10.1128/AAC.03514-14. Epub 2014 Sep 2.


KCNC3(R420H), a K(+) channel mutation causative in spinocerebellar ataxia 13 displays aberrant intracellular trafficking.

Gallego-Iradi C, Bickford JS, Khare S, Hall A, Nick JA, Salmasinia D, Wawrowsky K, Bannykh S, Huynh DP, Rincon-Limas DE, Pulst SM, Nick HS, Fernandez-Funez P, Waters MF.

Neurobiol Dis. 2014 Nov;71:270-9. doi: 10.1016/j.nbd.2014.08.020. Epub 2014 Aug 22.


Expression of antimicrobial drug tolerance by attached communities of Mycobacterium tuberculosis.

Ackart DF, Hascall-Dove L, Caceres SM, Kirk NM, Podell BK, Melander C, Orme IM, Leid JG, Nick JA, Basaraba RJ.

Pathog Dis. 2014 Apr;70(3):359-69. doi: 10.1111/2049-632X.12144. Epub 2014 Feb 24.


Azithromycin may antagonize inhaled tobramycin when targeting Pseudomonas aeruginosa in cystic fibrosis.

Nick JA, Moskowitz SM, Chmiel JF, Forssén AV, Kim SH, Saavedra MT, Saiman L, Taylor-Cousar JL, Nichols DP.

Ann Am Thorac Soc. 2014 Mar;11(3):342-50. doi: 10.1513/AnnalsATS.201310-352OC.


Clinical significance of a first positive nontuberculous mycobacteria culture in cystic fibrosis.

Martiniano SL, Sontag MK, Daley CL, Nick JA, Sagel SD.

Ann Am Thorac Soc. 2014 Jan;11(1):36-44. doi: 10.1513/AnnalsATS.201309-310OC.


The role of leptin in the development of pulmonary neutrophilia in infection and acute lung injury.

Ubags ND, Vernooy JH, Burg E, Hayes C, Bement J, Dilli E, Zabeau L, Abraham E, Poch KR, Nick JA, Dienz O, Zuñiga J, Wargo MJ, Mizgerd JP, Tavernier J, Rincón M, Poynter ME, Wouters EF, Suratt BT.

Crit Care Med. 2014 Feb;42(2):e143-51. doi: 10.1097/CCM.0000000000000048.


Blood mRNA biomarkers for detection of treatment response in acute pulmonary exacerbations of cystic fibrosis.

Nick JA, Sanders LA, Ickes B, Briones NJ, Caceres SM, Malcolm KC, Brayshaw SJ, Chacon CS, Barboa CM, Jones MC, St Clair C, Taylor-Cousar JL, Nichols DP, Sagel SD, Strand M, Saavedra MT.

Thorax. 2013 Oct;68(10):929-37. doi: 10.1136/thoraxjnl-2012-202278. Epub 2013 Jun 19.


p53 Integrates host defense and cell fate during bacterial pneumonia.

Madenspacher JH, Azzam KM, Gowdy KM, Malcolm KC, Nick JA, Dixon D, Aloor JJ, Draper DW, Guardiola JJ, Shatz M, Menendez D, Lowe J, Lu J, Bushel P, Li L, Merrick BA, Resnick MA, Fessler MB.

J Exp Med. 2013 May 6;210(5):891-904. doi: 10.1084/jem.20121674. Epub 2013 Apr 29.


Selective metabolism of hypothiocyanous acid by mammalian thioredoxin reductase promotes lung innate immunity and antioxidant defense.

Chandler JD, Nichols DP, Nick JA, Hondal RJ, Day BJ.

J Biol Chem. 2013 Jun 21;288(25):18421-8. doi: 10.1074/jbc.M113.468090. Epub 2013 Apr 29.


Effects of azithromycin in Pseudomonas aeruginosa burn wound infection.

Nichols DP, Caceres S, Caverly L, Fratelli C, Kim SH, Malcolm K, Poch KR, Saavedra M, Solomon G, Taylor-Cousar J, Moskowitz S, Nick JA.

J Surg Res. 2013 Aug;183(2):767-76. doi: 10.1016/j.jss.2013.02.003. Epub 2013 Feb 24.


Mycobacterium abscessus induces a limited pattern of neutrophil activation that promotes pathogen survival.

Malcolm KC, Nichols EM, Caceres SM, Kret JE, Martiniano SL, Sagel SD, Chan ED, Caverly L, Solomon GM, Reynolds P, Bratton DL, Taylor-Cousar JL, Nichols DP, Saavedra MT, Nick JA.

PLoS One. 2013;8(2):e57402. doi: 10.1371/journal.pone.0057402. Epub 2013 Feb 25.


Neutrophils regulate tissue Neutrophilia in inflammation via the oxidant-modified lipid lysophosphatidylserine.

Frasch SC, Fernandez-Boyanapalli RF, Berry KA, Murphy RC, Leslie CC, Nick JA, Henson PM, Bratton DL.

J Biol Chem. 2013 Feb 15;288(7):4583-93. doi: 10.1074/jbc.M112.438507. Epub 2013 Jan 5.


Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR.

Young RL, Malcolm KC, Kret JE, Caceres SM, Poch KR, Nichols DP, Taylor-Cousar JL, Saavedra MT, Randell SH, Vasil ML, Burns JL, Moskowitz SM, Nick JA.

PLoS One. 2011;6(9):e23637. doi: 10.1371/journal.pone.0023637. Epub 2011 Sep 1.


Bacteria-specific neutrophil dysfunction associated with interferon-stimulated gene expression in the acute respiratory distress syndrome.

Malcolm KC, Kret JE, Young RL, Poch KR, Caceres SM, Douglas IS, Coldren CD, Burnham EL, Moss M, Nick JA.

PLoS One. 2011;6(7):e21958. doi: 10.1371/journal.pone.0021958. Epub 2011 Jul 6.


Disruption of contact lens-associated Pseudomonas aeruginosa biofilms formed in the presence of neutrophils.

Robertson DM, Parks QM, Young RL, Kret J, Poch KR, Malcolm KC, Nichols DP, Nichols M, Zhu M, Cavanagh HD, Nick JA.

Invest Ophthalmol Vis Sci. 2011 Apr 27;52(5):2844-50. doi: 10.1167/iovs.10-6469. Print 2011 Apr.

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