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Select item 236302281.

p53 integrates host defense and cell fate during bacterial pneumonia.

Madenspacher JH, Azzam KM, Gowdy KM, Malcolm KC, Nick JA, Dixon D, Aloor JJ, Draper DW, Guardiola JJ, Shatz M, Menendez D, Lowe J, Lu J, Bushel P, Li L, Merrick BA, Resnick MA, Fessler MB.

J Exp Med. 2013 May 6;210(5):891-904. doi: 10.1084/jem.20121674. Epub 2013 Apr 29.

PMID:: 23630228; [PubMed - in process]

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Select item 236296602.

Selective Metabolism of Hypothiocyanous Acid by Mammalian Thioredoxin Reductase Promotes Lung Innate Immunity and Antioxidant Defense.

Chandler JD, Nichols DP, Nick JA, Hondal RJ, Day BJ.

J Biol Chem. 2013 Apr 29. [Epub ahead of print]

PMID:: 23629660; [PubMed - as supplied by publisher]

Free Article

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Select item 234780863.

Effects of azithromycin in Pseudomonas aeruginosa burn wound infection.

Nichols DP, Caceres S, Caverly L, Fratelli C, Kim SH, Malcolm K, Poch KR, Saavedra M, Solomon G, Taylor-Cousar J, Moskowitz S, Nick JA.

J Surg Res. 2013 Feb 24. doi:pii: S0022-4804(13)00088-7. 10.1016/j.jss.2013.02.003. [Epub ahead of print]

PMID:: 23478086; [PubMed - as supplied by publisher]

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Select item 234512204.

Mycobacterium abscessus induces a limited pattern of neutrophil activation that promotes pathogen survival.

Malcolm KC, Nichols EM, Caceres SM, Kret JE, Martiniano SL, Sagel SD, Chan ED, Caverly L, Solomon GM, Reynolds P, Bratton DL, Taylor-Cousar JL, Nichols DP, Saavedra MT, Nick JA.

PLoS One. 2013;8(2):e57402. doi: 10.1371/journal.pone.0057402. Epub 2013 Feb 25.

PMID:: 23451220; [PubMed - in process]

Free PMC Article

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Select item 232930645.

Neutrophils regulate tissue Neutrophilia in inflammation via the oxidant-modified lipid lysophosphatidylserine.

Frasch SC, Fernandez-Boyanapalli RF, Berry KA, Murphy RC, Leslie CC, Nick JA, Henson PM, Bratton DL.

J Biol Chem. 2013 Feb 15;288(7):4583-93. doi: 10.1074/jbc.M112.438507. Epub 2013 Jan 5.

PMID:: 23293064; [PubMed - indexed for MEDLINE]

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Select item 219094036.

Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR.

Young RL, Malcolm KC, Kret JE, Caceres SM, Poch KR, Nichols DP, Taylor-Cousar JL, Saavedra MT, Randell SH, Vasil ML, Burns JL, Moskowitz SM, Nick JA.

PLoS One. 2011;6(9):e23637. doi: 10.1371/journal.pone.0023637. Epub 2011 Sep 1.

PMID:: 21909403; [PubMed - indexed for MEDLINE]

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Select item 217550137.

Bacteria-specific neutrophil dysfunction associated with interferon-stimulated gene expression in the acute respiratory distress syndrome.

Malcolm KC, Kret JE, Young RL, Poch KR, Caceres SM, Douglas IS, Coldren CD, Burnham EL, Moss M, Nick JA.

PLoS One. 2011;6(7):e21958. doi: 10.1371/journal.pone.0021958. Epub 2011 Jul 6.

PMID:: 21755013; [PubMed - indexed for MEDLINE]

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Select item 212453968.

Disruption of contact lens-associated Pseudomonas aeruginosa biofilms formed in the presence of neutrophils.

Robertson DM, Parks QM, Young RL, Kret J, Poch KR, Malcolm KC, Nichols DP, Nichols M, Zhu M, Cavanagh HD, Nick JA.

Invest Ophthalmol Vis Sci. 2011 Apr 27;52(5):2844-50. doi: 10.1167/iovs.10-6469. Print 2011 Apr.

PMID:: 21245396; [PubMed - indexed for MEDLINE]

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Select item 206756789.

Cystic fibrosis pulmonary guidelines: pulmonary complications: hemoptysis and pneumothorax.

Flume PA, Mogayzel PJ Jr, Robinson KA, Rosenblatt RL, Quittell L, Marshall BC; Clinical Practice Guidelines for Pulmonary Therapies Committee; Cystic Fibrosis Foundation Pulmonary Therapies Committee.

Am J Respir Crit Care Med. 2010 Aug 1;182(3):298-306. doi: 10.1164/rccm.201002-0157CI.

PMID:: 20675678; [PubMed - indexed for MEDLINE]

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Select item 2044809110.

Effects of gender and age at diagnosis on disease progression in long-term survivors of cystic fibrosis.

Nick JA, Chacon CS, Brayshaw SJ, Jones MC, Barboa CM, St Clair CG, Young RL, Nichols DP, Janssen JS, Huitt GA, Iseman MD, Daley CL, Taylor-Cousar JL, Accurso FJ, Saavedra MT, Sontag MK.

Am J Respir Crit Care Med. 2010 Sep 1;182(5):614-26. doi: 10.1164/rccm.201001-0092OC. Epub 2010 May 6.

PMID:: 20448091; [PubMed - indexed for MEDLINE]

Free PMC Article

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Select item 1973809211.

Genetic modifiers of liver disease in cystic fibrosis.

Bartlett JR, Friedman KJ, Ling SC, Pace RG, Bell SC, Bourke B, Castaldo G, Castellani C, Cipolli M, Colombo C, Colombo JL, Debray D, Fernandez A, Lacaille F, Macek M Jr, Rowland M, Salvatore F, Taylor CJ, Wainwright C, Wilschanski M, Zemková D, Hannah WB, Phillips MJ, Corey M, Zielenski J, Dorfman R, Wang Y, Zou F, Silverman LM, Drumm ML, Wright FA, Lange EM, Durie PR, Knowles MR; Gene Modifier Study Group.

JAMA. 2009 Sep 9;302(10):1076-83. doi: 10.1001/jama.2009.1295.

PMID:: 19738092; [PubMed - indexed for MEDLINE]

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Select item 1927364612.

Neutrophil enhancement of Pseudomonas aeruginosa biofilm development: human F-actin and DNA as targets for therapy.

Parks QM, Young RL, Poch KR, Malcolm KC, Vasil ML, Nick JA.

J Med Microbiol. 2009 Apr;58(Pt 4):492-502. doi: 10.1099/jmm.0.005728-0.

PMID:: 19273646; [PubMed - indexed for MEDLINE]

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Select item 1872343513.

Circulating RNA transcripts identify therapeutic response in cystic fibrosis lung disease.

Saavedra MT, Hughes GJ, Sanders LA, Carr M, Rodman DM, Coldren CD, Geraci MW, Sagel SD, Accurso FJ, West J, Nick JA.

Am J Respir Crit Care Med. 2008 Nov 1;178(9):929-38. doi: 10.1164/rccm.200803-387OC. Epub 2008 Aug 21.

PMID:: 18723435; [PubMed - indexed for MEDLINE]

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Select item 1829255514.

Effects of liver X receptor agonist treatment on pulmonary inflammation and host defense.

Smoak K, Madenspacher J, Jeyaseelan S, Williams B, Dixon D, Poch KR, Nick JA, Worthen GS, Fessler MB.

J Immunol. 2008 Mar 1;180(5):3305-12.

PMID:: 18292555; [PubMed - indexed for MEDLINE]

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Select item 1821899415.

Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways.

Saavedra MT, Patterson AD, West J, Randell SH, Riches DW, Malcolm KC, Cool CD, Nick JA, Dinarello CA.

Am J Respir Cell Mol Biol. 2008 Jun;38(6):679-88. doi: 10.1165/rcmb.2007-0282OC. Epub 2008 Jan 24.

PMID:: 18218994; [PubMed - indexed for MEDLINE]

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Select item 1758174016.

HMGB1 and LPS induce distinct patterns of gene expression and activation in neutrophils from patients with sepsis-induced acute lung injury.

Silva E, Arcaroli J, He Q, Svetkauskaite D, Coldren C, Nick JA, Poch K, Park JS, Banerjee A, Abraham E.

Intensive Care Med. 2007 Oct;33(10):1829-39. Epub 2007 Jun 21.

PMID:: 17581740; [PubMed - indexed for MEDLINE]

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Select item 1708264117.

Systemic inhibition of the angiotensin-converting enzyme limits lipopolysaccharide-induced lung neutrophil recruitment through both bradykinin and angiotensin II-regulated pathways.

Arndt PG, Young SK, Poch KR, Nick JA, Falk S, Schrier RW, Worthen GS.

J Immunol. 2006 Nov 15;177(10):7233-41.

PMID:: 17082641; [PubMed - indexed for MEDLINE]

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Select item 1701886018.

Dual role for RhoA in suppression and induction of cytokines in the human neutrophil.

Fessler MB, Arndt PG, Just I, Nick JA, Malcolm KC, Worthen GS.

Blood. 2007 Feb 1;109(3):1248-56. Epub 2006 Oct 3.

PMID:: 17018860; [PubMed - indexed for MEDLINE]

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Select item 1686138419.

Functional and genomic changes induced by alveolar transmigration in human neutrophils.

Coldren CD, Nick JA, Poch KR, Woolum MD, Fouty BW, O'Brien JM, Gruber MP, Zamora MR, Svetkauskaite D, Richter DA, He Q, Park JS, Overdier KH, Abraham E, Geraci MW.

Am J Physiol Lung Cell Mol Physiol. 2006 Dec;291(6):L1267-76. Epub 2006 Jul 21.

PMID:: 16861384; [PubMed - indexed for MEDLINE]

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Select item 1675142320.

Peripheral blood neutrophil activation patterns are associated with pulmonary inflammatory responses to lipopolysaccharide in humans.

Abraham E, Nick JA, Azam T, Kim SH, Mira JP, Svetkauskaite D, He Q, Zamora M, Murphy J, Park JS, Overdier K, Dinarello CA.

J Immunol. 2006 Jun 15;176(12):7753-60.

PMID:: 16751423; [PubMed - indexed for MEDLINE]

Free Article

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15 free full-text articles in PubMed Central

Mycobacterium abscessus induces a limited pattern of neutrophil activation that promotes pathogen survival. [PLoS One. 2013]
Mycobacterium abscessus induces a limited pattern of neutrophil activation that promotes pathogen survival.
Malcolm KC, Nichols EM, Caceres SM, Kret JE, Martiniano SL, Sagel SD, Chan ED, Caverly L, Solomon GM, Reynolds P, et al. PLoS One. 2013; 8(2):e57402. Epub 2013 Feb 25.
Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR. [PLoS One. 2011]
Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR.
Young RL, Malcolm KC, Kret JE, Caceres SM, Poch KR, Nichols DP, Taylor-Cousar JL, Saavedra MT, Randell SH, Vasil ML, et al. PLoS One. 2011; 6(9):e23637. Epub 2011 Sep 1.
Bacteria-specific neutrophil dysfunction associated with interferon-stimulated gene expression in the acute respiratory distress syndrome. [PLoS One. 2011]
Bacteria-specific neutrophil dysfunction associated with interferon-stimulated gene expression in the acute respiratory distress syndrome.
Malcolm KC, Kret JE, Young RL, Poch KR, Caceres SM, Douglas IS, Coldren CD, Burnham EL, Moss M, Nick JA. PLoS One. 2011; 6(7):e21958. Epub 2011 Jul 6.