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Results: 1 to 20 of 171

1.

Biochemical Characterization of the Phosphatase Domain of the Tumor Suppressor PH Domain Leucine-Rich Repeat Protein Phosphatase.

Sierecki E, Newton AC.

Biochemistry. 2014 Jun 24;53(24):3971-81. doi: 10.1021/bi500428j. Epub 2014 Jun 12.

PMID:
24892992
[PubMed - in process]
2.

Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt.

Wang P, Zhou Z, Hu A, Ponte de Albuquerque C, Zhou Y, Hong L, Sierecki E, Ajiro M, Kruhlak M, Harris C, Guan KL, Zheng ZM, Newton AC, Sun P, Zhou H, Fu XD.

Mol Cell. 2014 May 8;54(3):378-91. doi: 10.1016/j.molcel.2014.03.007. Epub 2014 Apr 3.

PMID:
24703948
[PubMed - indexed for MEDLINE]
3.

Understanding the genetic control and physiological traits associated with rhizosheath production by barley (Hordeum vulgare).

George TS, Brown LK, Ramsay L, White PJ, Newton AC, Bengough AG, Russell J, Thomas WT.

New Phytol. 2014 Jul;203(1):195-205. doi: 10.1111/nph.12786. Epub 2014 Mar 28.

PMID:
24684319
[PubMed - in process]
4.

Intramolecular conformational changes optimize protein kinase C signaling.

Antal CE, Violin JD, Kunkel MT, Skovsø S, Newton AC.

Chem Biol. 2014 Apr 24;21(4):459-69. doi: 10.1016/j.chembiol.2014.02.008. Epub 2014 Mar 13.

PMID:
24631122
[PubMed - in process]
5.

Protein kinase Cδ-mediated phosphorylation of Connexin43 gap junction channels causes movement within gap junctions followed by vesicle internalization and protein degradation.

Cone AC, Cavin G, Ambrosi C, Hakozaki H, Wu-Zhang AX, Kunkel MT, Newton AC, Sosinsky GE.

J Biol Chem. 2014 Mar 28;289(13):8781-98. doi: 10.1074/jbc.M113.533265. Epub 2014 Feb 5.

PMID:
24500718
[PubMed - indexed for MEDLINE]
6.

Turning off AKT: PHLPP as a drug target.

Newton AC, Trotman LC.

Annu Rev Pharmacol Toxicol. 2014;54:537-58. doi: 10.1146/annurev-pharmtox-011112-140338.

PMID:
24392697
[PubMed - in process]
Free PMC Article
7.

Carbon pools recover more quickly than plant biodiversity in tropical secondary forests.

Martin PA, Newton AC, Bullock JM.

Proc Biol Sci. 2013 Nov 6;280(1773):20132236. doi: 10.1098/rspb.2013.2236. Print 2013 Dec 22. Erratum in: Proc Biol Sci. 2014 May 7;281(1782):20140303.

PMID:
24197410
[PubMed - indexed for MEDLINE]
8.

Imaging kinase activity at protein scaffolds.

Kunkel MT, Newton AC.

Methods Mol Biol. 2014;1071:129-37. doi: 10.1007/978-1-62703-622-1_10.

PMID:
24052385
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Spatiotemporal dynamics of phosphorylation in lipid second messenger signaling.

Antal CE, Newton AC.

Mol Cell Proteomics. 2013 Dec;12(12):3498-508. doi: 10.1074/mcp.R113.029819. Epub 2013 Jun 20. Review.

PMID:
23788531
[PubMed - indexed for MEDLINE]
10.

Protein kinase C pharmacology: refining the toolbox.

Wu-Zhang AX, Newton AC.

Biochem J. 2013 Jun 1;452(2):195-209. doi: 10.1042/BJ20130220. Review.

PMID:
23662807
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Electrostatic and hydrophobic interactions differentially tune membrane binding kinetics of the C2 domain of protein kinase Cα.

Scott AM, Antal CE, Newton AC.

J Biol Chem. 2013 Jun 7;288(23):16905-15. doi: 10.1074/jbc.M113.467456. Epub 2013 Apr 15.

PMID:
23589289
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Ultrafast dynamics in iron tetracarbonyl olefin complexes investigated with two-dimensional vibrational spectroscopy.

Panman MR, Newton AC, Vos J, van den Bosch B, Bocokić V, Reek JN, Woutersen S.

Phys Chem Chem Phys. 2013 Jan 28;15(4):1115-22. doi: 10.1039/c2cp43565a.

PMID:
23223560
[PubMed]
13.

Isozyme-specific interaction of protein kinase Cδ with mitochondria dissected using live cell fluorescence imaging.

Wu-Zhang AX, Murphy AN, Bachman M, Newton AC.

J Biol Chem. 2012 Nov 2;287(45):37891-906. doi: 10.1074/jbc.M112.412635. Epub 2012 Sep 17.

PMID:
22988234
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Climate Change and Defense against Pathogens in Plants.

Newton AC, Torrance L, Holden N, Toth IK, Cooke DE, Blok V, Gilroy EM.

Adv Appl Microbiol. 2012;81:89-132. doi: 10.1016/B978-0-12-394382-8.00003-4.

PMID:
22958528
[PubMed - in process]
15.

Euphohelioscopin A is a PKC activator capable of inducing macrophage differentiation.

de Lichtervelde L, Antal CE, Boitano AE, Wang Y, Krastel P, Petersen F, Newton AC, Cooke MP, Schultz PG.

Chem Biol. 2012 Aug 24;19(8):994-1000. doi: 10.1016/j.chembiol.2012.06.010.

PMID:
22921066
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Shedding light on local kinase activation.

Scott JD, Newton AC.

BMC Biol. 2012 Jul 17;10:61. doi: 10.1186/1741-7007-10-61.

PMID:
22805055
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Pathogen populations evolve to greater race complexity in agricultural systems--evidence from analysis of Rhynchosporium secalis virulence data.

Zhan J, Yang L, Zhu W, Shang L, Newton AC.

PLoS One. 2012;7(6):e38611. doi: 10.1371/journal.pone.0038611. Epub 2012 Jun 18.

PMID:
22723870
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Cellular pharmacology of protein kinase Mζ (PKMζ) contrasts with its in vitro profile: implications for PKMζ as a mediator of memory.

Wu-Zhang AX, Schramm CL, Nabavi S, Malinow R, Newton AC.

J Biol Chem. 2012 Apr 13;287(16):12879-85. doi: 10.1074/jbc.M112.357244. Epub 2012 Feb 29.

PMID:
22378786
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Suppression of survival signalling pathways by the phosphatase PHLPP.

O'Neill AK, Niederst MJ, Newton AC.

FEBS J. 2013 Jan;280(2):572-83. doi: 10.1111/j.1742-4658.2012.08537.x. Epub 2012 Mar 16.

PMID:
22340730
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Peptidyl-prolyl isomerase Pin1 controls down-regulation of conventional protein kinase C isozymes.

Abrahamsen H, O'Neill AK, Kannan N, Kruse N, Taylor SS, Jennings PA, Newton AC.

J Biol Chem. 2012 Apr 13;287(16):13262-78. doi: 10.1074/jbc.M112.349753. Epub 2012 Feb 8.

PMID:
22318721
[PubMed - indexed for MEDLINE]
Free PMC Article

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