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Results: 1 to 20 of 265

1.

Utilization of the eμ-myc mouse to model heterogeneity of therapeutic response.

Rempel RE, Jiang X, Fullerton P, Tan TZ, Ye J, Lau JA, Mori S, Chi JT, Nevins JR, Friedman DR.

Mol Cancer Ther. 2014 Dec;13(12):3219-29. doi: 10.1158/1535-7163.MCT-13-0044. Epub 2014 Oct 27.

PMID:
25349303
[PubMed - in process]
2.

Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control.

Dong P, Maddali MV, Srimani JK, Thélot F, Nevins JR, Mathey-Prevot B, You L.

Nat Commun. 2014 Sep 1;5:4750. doi: 10.1038/ncomms5750.

PMID:
25175461
[PubMed - in process]
Free PMC Article
3.

FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function.

Shats I, Gatza ML, Liu B, Angus SP, You L, Nevins JR.

Cancer Res. 2013 Oct 1;73(19):6056-67. doi: 10.1158/0008-5472.CAN-13-0453. Epub 2013 Aug 21.

PMID:
23966291
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Interaction of E2F7 transcription factor with E2F1 and C-terminal-binding protein (CtBP) provides a mechanism for E2F7-dependent transcription repression.

Liu B, Shats I, Angus SP, Gatza ML, Nevins JR.

J Biol Chem. 2013 Aug 23;288(34):24581-9. doi: 10.1074/jbc.M113.467506. Epub 2013 Jul 13.

PMID:
23853115
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

E2F6 associates with BRG1 in transcriptional regulation.

Leung JY, Nevins JR.

PLoS One. 2012;7(10):e47967. doi: 10.1371/journal.pone.0047967. Epub 2012 Oct 17.

PMID:
23082233
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest.

Angus SP, Nevins JR.

Oncogene. 2012 Nov 1;31(44):4709-17. doi: 10.1038/onc.2011.622. Epub 2012 Jan 16.

PMID:
22249253
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Retraction: Acharya CR, et al. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer. JAMA. 2008;299(13):1574-1587.

Acharya CR, Hsu DS, Anders CK, Anguiano A, Salter KH, Walters KS, Redman RC, Tuchman SA, Moylan CA, Mukherjee S, Barry WT, Dressman HK, Ginsburg GS, Marcom KP, Garman KS, Lyman GH, Nevins JR, Potti A.

JAMA. 2012 Feb 1;307(5):453. doi: 10.1001/jama.2012.2. Epub 2012 Jan 6. No abstract available.

PMID:
22228686
[PubMed - indexed for MEDLINE]
8.

SIGNATURE: a workbench for gene expression signature analysis.

Chang JT, Gatza ML, Lucas JE, Barry WT, Vaughn P, Nevins JR.

BMC Bioinformatics. 2011 Nov 14;12:443. doi: 10.1186/1471-2105-12-443.

PMID:
22078435
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Heterogeneity in MYC-induced mammary tumors contributes to escape from oncogene dependence.

Leung JY, Andrechek ER, Cardiff RD, Nevins JR.

Oncogene. 2012 May 17;31(20):2545-54. doi: 10.1038/onc.2011.433. Epub 2011 Sep 26.

PMID:
21996730
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Retraction for Garman et al: A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities.

Garman KS, Acharya CR, Edelman E, Grade M, Gaedcke J, Sud S, Barry W, Diehl AM, Provenzale D, Ginsburg GS, Ghadimi BM, Ried T, Nevins JR, Mukherjee S, Hsu D, Potti A.

Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17569. doi: 10.1073/pnas.1115170108. Epub 2011 Oct 3. No abstract available.

PMID:
21969600
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Network calisthenics: control of E2F dynamics in cell cycle entry.

Wong JV, Dong P, Nevins JR, Mathey-Prevot B, You L.

Cell Cycle. 2011 Sep 15;10(18):3086-94. Epub 2011 Sep 15. Review.

PMID:
21900750
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Peripheral blood signatures of lead exposure.

LaBreche HG, Meadows SK, Nevins JR, Chute JP.

PLoS One. 2011;6(8):e23043. doi: 10.1371/journal.pone.0023043. Epub 2011 Aug 1.

PMID:
21829687
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Integrating factor analysis and a transgenic mouse model to reveal a peripheral blood predictor of breast tumors.

LaBreche HG, Nevins JR, Huang E.

BMC Med Genomics. 2011 Jul 22;4:61. doi: 10.1186/1755-8794-4-61.

PMID:
21781289
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A methodology for utilization of predictive genomic signatures in FFPE samples.

Freedman JA, Augustine CK, Selim AM, Holshausen KC, Wei Z, Tsamis KA, Hsu DS, Dressman HK, Barry WT, Tyler DS, Nevins JR.

BMC Med Genomics. 2011 Jul 11;4:58. doi: 10.1186/1755-8794-4-58.

PMID:
21745407
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Use of gene expression and pathway signatures to characterize the complexity of human melanoma.

Freedman JA, Tyler DS, Nevins JR, Augustine CK.

Am J Pathol. 2011 Jun;178(6):2513-22. doi: 10.1016/j.ajpath.2011.02.037.

PMID:
21641377
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Using noisy gene expression mediated by engineered adenovirus to probe signaling dynamics in mammalian cells.

Wong JV, Yao G, Nevins JR, You L.

Methods Enzymol. 2011;497:221-37. doi: 10.1016/B978-0-12-385075-1.00010-X.

PMID:
21601089
[PubMed - indexed for MEDLINE]
17.

Pathway-based classification of lung cancer: a strategy to guide therapeutic selection.

Nevins JR.

Proc Am Thorac Soc. 2011 May;8(2):180-2. doi: 10.1513/pats.201006-040MS.

PMID:
21543798
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Origin of bistability underlying mammalian cell cycle entry.

Yao G, Tan C, West M, Nevins JR, You L.

Mol Syst Biol. 2011 Apr 26;7:485. doi: 10.1038/msb.2011.19.

PMID:
21525871
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Retraction: A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer. N Engl J Med 2006;355:570-80.

Potti A, Mukherjee S, Petersen R, Dressman HK, Bild A, Koontz J, Kratzke R, Watson MA, Kelley M, Ginsburg GS, West M, Harpole DH Jr, Nevins JR.

N Engl J Med. 2011 Mar 24;364(12):1176. doi: 10.1056/NEJMc1101915. Epub 2011 Mar 2.

PMID:
21366430
[PubMed - indexed for MEDLINE]
20.

Viral-mediated noisy gene expression reveals biphasic E2f1 response to MYC.

Wong JV, Yao G, Nevins JR, You L.

Mol Cell. 2011 Feb 4;41(3):275-85. doi: 10.1016/j.molcel.2011.01.014.

PMID:
21292160
[PubMed - indexed for MEDLINE]
Free PMC Article
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