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Results: 1 to 20 of 175

1.

Hypermethylation of the TGF-β target, ABCA1 is associated with poor prognosis in ovarian cancer patients.

Chou JL, Huang RL, Shay J, Chen LY, Lin SJ, Yan PS, Chao WT, Lai YH, Lai YL, Chao TK, Lee CI, Tai CK, Wu SF, Nephew KP, Huang TH, Lai HC, Chan MW.

Clin Epigenetics. 2015 Jan 14;7(1):1. doi: 10.1186/s13148-014-0036-2. eCollection 2015.

2.

Stranded Whole Transcriptome RNA-Seq for All RNA Types.

Miller DF, Yan PX, Fang F, Buechlein A, Ford JB, Tang H, Huang TH, Burow ME, Liu Y, Rusch DB, Nephew KP.

Curr Protoc Hum Genet. 2015 Jan 20;84:11.14.1-11.14.23. doi: 10.1002/0471142905.hg1114s84.

PMID:
25599667
3.

A mathematical model of bimodal epigenetic control of miR-193a in ovarian cancer stem cells.

Cheng FH, Aguda BD, Tsai JC, Kochańczyk M, Lin JM, Chen GC, Lai HC, Nephew KP, Hwang TW, Chan MW.

PLoS One. 2014 Dec 29;9(12):e116050. doi: 10.1371/journal.pone.0116050. eCollection 2014.

4.

Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer.

Chen Z, Lan X, Thomas-Ahner JM, Wu D, Liu X, Ye Z, Wang L, Sunkel B, Grenade C, Chen J, Zynger DL, Yan PS, Huang J, Nephew KP, Huang TH, Lin S, Clinton SK, Li W, Jin VX, Wang Q.

EMBO J. 2015 Feb 12;34(4):502-16. doi: 10.15252/embj.201490306. Epub 2014 Dec 22.

PMID:
25535248
5.

TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells.

Cardenas H, Vieth E, Lee J, Segar M, Liu Y, Nephew KP, Matei D.

Epigenetics. 2014;9(11):1461-72. doi: 10.4161/15592294.2014.971608.

PMID:
25470663
6.

Estrogen induces global reorganization of chromatin structure in human breast cancer cells.

Mourad R, Hsu PY, Juan L, Shen C, Koneru P, Lin H, Liu Y, Nephew K, Huang TH, Li L.

PLoS One. 2014 Dec 3;9(12):e113354. doi: 10.1371/journal.pone.0113354. eCollection 2014.

7.

MiR-373 targeting of the Rab22a oncogene suppresses tumor invasion and metastasis in ovarian cancer.

Zhang Y, Zhao FJ, Chen LL, Wang LQ, Nephew KP, Wu YL, Zhang S.

Oncotarget. 2014 Dec 15;5(23):12291-303.

8.

Global DNA methylation profiling technologies and the ovarian cancer methylome.

Tang J, Fang F, Miller DF, Pilrose JM, Matei D, Huang TH, Nephew KP.

Methods Mol Biol. 2015;1238:653-75. doi: 10.1007/978-1-4939-1804-1_34.

PMID:
25421685
9.

Mg2+ effect on argonaute and RNA duplex by molecular dynamics and bioinformatics implications.

Nam S, Ryu H, Son WJ, Kim YH, Kim KT, Balch C, Nephew KP, Lee J.

PLoS One. 2014 Oct 17;9(10):e109745. doi: 10.1371/journal.pone.0109745. eCollection 2014.

10.

Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells.

Zhuang Y, Nguyen HT, Burow ME, Zhuo Y, El-Dahr SS, Yao X, Cao S, Flemington EK, Nephew KP, Fang F, Collins-Burow B, Rhodes LV, Yu Q, Jayawickramarajah J, Shan B.

Mol Carcinog. 2014 Oct 18. doi: 10.1002/mc.22237. [Epub ahead of print]

PMID:
25328122
11.

The novel, small-molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer.

Fang F, Munck J, Tang J, Taverna P, Wang Y, Miller DF, Pilrose J, Choy G, Azab M, Pawelczak KS, VanderVere-Carozza P, Wagner M, Lyons J, Matei D, Turchi JJ, Nephew KP.

Clin Cancer Res. 2014 Dec 15;20(24):6504-16. doi: 10.1158/1078-0432.CCR-14-1553. Epub 2014 Oct 14.

PMID:
25316809
12.

microRNA regulation of mammalian target of rapamycin expression and activity controls estrogen receptor function and RAD001 sensitivity.

Martin EC, Rhodes LV, Elliott S, Krebs AE, Nephew KP, Flemington EK, Collins-Burow BM, Burow ME.

Mol Cancer. 2014 Oct 6;13:229. doi: 10.1186/1476-4598-13-229.

13.

BioVLAB-MMIA-NGS: microRNA-mRNA integrated analysis using high-throughput sequencing data.

Chae H, Rhee S, Nephew KP, Kim S.

Bioinformatics. 2015 Jan 15;31(2):265-7. doi: 10.1093/bioinformatics/btu614. Epub 2014 Sep 29.

PMID:
25270639
14.

Epigenetic targeting of ovarian cancer stem cells.

Wang Y, Cardenas H, Fang F, Condello S, Taverna P, Segar M, Liu Y, Nephew KP, Matei D.

Cancer Res. 2014 Sep 1;74(17):4922-36. doi: 10.1158/0008-5472.CAN-14-1022. Epub 2014 Jul 17.

PMID:
25035395
15.

Effects of the endocrine-disrupting chemical DDT on self-renewal and differentiation of human mesenchymal stem cells.

Strong AL, Shi Z, Strong MJ, Miller DF, Rusch DB, Buechlein AM, Flemington EK, McLachlan JA, Nephew KP, Burow ME, Bunnell BA.

Environ Health Perspect. 2015 Jan;123(1):42-8. doi: 10.1289/ehp.1408188. Epub 2014 Jul 11.

16.

Decitabine reactivated pathways in platinum resistant ovarian cancer.

Fang F, Zuo Q, Pilrose J, Wang Y, Shen C, Li M, Wulfridge P, Matei D, Nephew KP.

Oncotarget. 2014 Jun 15;5(11):3579-89.

17.

Three-tiered role of the pioneer factor GATA2 in promoting androgen-dependent gene expression in prostate cancer.

Wu D, Sunkel B, Chen Z, Liu X, Ye Z, Li Q, Grenade C, Ke J, Zhang C, Chen H, Nephew KP, Huang TH, Liu Z, Jin VX, Wang Q.

Nucleic Acids Res. 2014 Apr;42(6):3607-22. doi: 10.1093/nar/gkt1382. Epub 2014 Jan 13.

18.

Hypomethylation signature of tumor-initiating cells predicts poor prognosis of ovarian cancer patients.

Liao YP, Chen LY, Huang RL, Su PH, Chan MW, Chang CC, Yu MH, Wang PH, Yen MS, Nephew KP, Lai HC.

Hum Mol Genet. 2014 Apr 1;23(7):1894-906. doi: 10.1093/hmg/ddt583. Epub 2013 Nov 20.

19.

MEK5/ERK5 signaling suppresses estrogen receptor expression and promotes hormone-independent tumorigenesis.

Antoon JW, Martin EC, Lai R, Salvo VA, Tang Y, Nitzchke AM, Elliott S, Nam SY, Xiong W, Rhodes LV, Collins-Burow B, David O, Wang G, Shan B, Beckman BS, Nephew KP, Burow ME.

PLoS One. 2013 Aug 9;8(8):e69291. doi: 10.1371/journal.pone.0069291. eCollection 2013.

20.

Amplification of distant estrogen response elements deregulates target genes associated with tamoxifen resistance in breast cancer.

Hsu PY, Hsu HK, Lan X, Juan L, Yan PS, Labanowska J, Heerema N, Hsiao TH, Chiu YC, Chen Y, Liu Y, Li L, Li R, Thompson IM, Nephew KP, Sharp ZD, Kirma NB, Jin VX, Huang TH.

Cancer Cell. 2013 Aug 12;24(2):197-212. doi: 10.1016/j.ccr.2013.07.007.

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