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Items: 15


Pin1-targeted therapy against systemic lupus erythematosus.

Wei S, Yoshida N, Finn G, Kozono S, Nechama M, Kyttaris VC, Zhou XZ, Tsokos GC, Lu KP.

Arthritis Rheumatol. 2016 May 9. doi: 10.1002/art.39741. [Epub ahead of print]


Parathyroid-specific deletion of dicer-dependent microRNAs abrogates the response of the parathyroid to acute and chronic hypocalcemia and uremia.

Shilo V, Ben-Dov IZ, Nechama M, Silver J, Naveh-Many T.

FASEB J. 2015 Sep;29(9):3964-76. doi: 10.1096/fj.15-274191. Epub 2015 Jun 8.


Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer.

Wei S, Kozono S, Kats L, Nechama M, Li W, Guarnerio J, Luo M, You MH, Yao Y, Kondo A, Hu H, Bozkurt G, Moerke NJ, Cao S, Reschke M, Chen CH, Rego EM, Lo-Coco F, Cantley LC, Lee TH, Wu H, Zhang Y, Pandolfi PP, Zhou XZ, Lu KP.

Nat Med. 2015 May;21(5):457-66. doi: 10.1038/nm.3839. Epub 2015 Apr 13.


Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease.

Chen CH, Li W, Sultana R, You MH, Kondo A, Shahpasand K, Kim BM, Luo ML, Nechama M, Lin YM, Yao Y, Lee TH, Zhou XZ, Swomley AM, Allan Butterfield D, Zhang Y, Lu KP.

Neurobiol Dis. 2015 Apr;76:13-23. doi: 10.1016/j.nbd.2014.12.027. Epub 2015 Jan 6.


The scavenger receptor MARCO modulates TLR-induced responses in dendritic cells.

Kissick HT, Dunn LK, Ghosh S, Nechama M, Kobzik L, Arredouani MS.

PLoS One. 2014 Aug 4;9(8):e104148. doi: 10.1371/journal.pone.0104148. eCollection 2014.


An unusual two-step control of CPEB destruction by Pin1.

Nechama M, Lin CL, Richter JD.

Mol Cell Biol. 2013 Jan;33(1):48-58. doi: 10.1128/MCB.00904-12. Epub 2012 Oct 22.


KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells.

Nechama M, Peng Y, Bell O, Briata P, Gherzi R, Schoenberg DR, Naveh-Many T.

BMC Cell Biol. 2009 Sep 23;10:70. doi: 10.1186/1471-2121-10-70.


The peptidyl-prolyl isomerase Pin1 determines parathyroid hormone mRNA levels and stability in rat models of secondary hyperparathyroidism.

Nechama M, Uchida T, Mor Yosef-Levi I, Silver J, Naveh-Many T.

J Clin Invest. 2009 Oct;119(10):3102-14. doi: 10.1172/JCI39522. Epub 2009 Sep 21.


The calcium-sensing receptor regulates parathyroid hormone gene expression in transfected HEK293 cells.

Galitzer H, Lavi-Moshayoff V, Nechama M, Meir T, Silver J, Naveh-Many T.

BMC Biol. 2009 Apr 27;7:17. doi: 10.1186/1741-7007-7-17.


Regulation of PTH mRNA stability by the calcimimetic R568 and the phosphorus binder lanthanum carbonate in CKD.

Nechama M, Ben-Dov IZ, Silver J, Naveh-Many T.

Am J Physiol Renal Physiol. 2009 Apr;296(4):F795-800. doi: 10.1152/ajprenal.90625.2008. Epub 2009 Jan 7.


The mRNA decay promoting factor K-homology splicing regulator protein post-transcriptionally determines parathyroid hormone mRNA levels.

Nechama M, Ben-Dov IZ, Briata P, Gherzi R, Naveh-Many T.

FASEB J. 2008 Oct;22(10):3458-68. doi: 10.1096/fj.08-107250. Epub 2008 Jun 26.


Regulation of parathyroid hormone mRNA stability by calcium, phosphate and uremia.

Naveh-Many T, Nechama M.

Curr Opin Nephrol Hypertens. 2007 Jul;16(4):305-10. Review.


The critical role of residues 43R and 44Q of carcinoembryonic antigen cell adhesion molecules-1 in the protection from killing by human NK cells.

Markel G, Gruda R, Achdout H, Katz G, Nechama M, Blumberg RS, Kammerer R, Zimmermann W, Mandelboim O.

J Immunol. 2004 Sep 15;173(6):3732-9.


A new crystal form of XT6 enables a significant improvement of its diffraction quality and resolution.

Bar M, Golan G, Nechama M, Zolotnitsky G, Shoham Y, Shoham G.

Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):545-9. Epub 2004 Feb 25.


A simple spot test for the detection of fructose deficiency in semen.

Jungreis E, Nechama M, Paz G, Homonnai T.

Int J Androl. 1989 Jun;12(3):195-8.

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