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Results: 1 to 20 of 126

1.

Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH.

Urosevic J, Garcia-Albéniz X, Planet E, Real S, Céspedes MV, Guiu M, Fernandez E, Bellmunt A, Gawrzak S, Pavlovic M, Mangues R, Dolado I, Barriga FM, Nadal C, Kemeny N, Batlle E, Nebreda AR, Gomis RR.

Nat Cell Biol. 2014 Jul;16(7):685-94. doi: 10.1038/ncb2977. Epub 2014 Jun 1.

PMID:
24880666
[PubMed - in process]
2.

Dual function of p38α MAPK in colon cancer: suppression of colitis-associated tumor initiation but requirement for cancer cell survival.

Gupta J, del Barco Barrantes I, Igea A, Sakellariou S, Pateras IS, Gorgoulis VG, Nebreda AR.

Cancer Cell. 2014 Apr 14;25(4):484-500. doi: 10.1016/j.ccr.2014.02.019. Epub 2014 Mar 27.

PMID:
24684847
[PubMed - indexed for MEDLINE]
3.

Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK.

Pereira L, Igea A, Canovas B, Dolado I, Nebreda AR.

EMBO Mol Med. 2013 Nov;5(11):1759-74. doi: 10.1002/emmm.201302732. Epub 2013 Sep 24.

PMID:
24115572
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

p38 MAPK: a dual role in hepatocyte proliferation through reactive oxygen species.

Tormos AM, Taléns-Visconti R, Nebreda AR, Sastre J.

Free Radic Res. 2013 Nov;47(11):905-16. doi: 10.3109/10715762.2013.821200. Epub 2013 Oct 4. Review.

PMID:
23906070
[PubMed - indexed for MEDLINE]
5.

Multi-phosphorylation of the intrinsically disordered unique domain of c-Src studied by in-cell and real-time NMR spectroscopy.

Amata I, Maffei M, Igea A, Gay M, Vilaseca M, Nebreda AR, Pons M.

Chembiochem. 2013 Sep 23;14(14):1820-7. doi: 10.1002/cbic.201300139. Epub 2013 Jun 6.

PMID:
23744817
[PubMed - indexed for MEDLINE]
6.

Lipid binding by the Unique and SH3 domains of c-Src suggests a new regulatory mechanism.

Pérez Y, Maffei M, Igea A, Amata I, Gairí M, Nebreda AR, Bernadó P, Pons M.

Sci Rep. 2013;3:1295. doi: 10.1038/srep01295.

PMID:
23416516
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

SnapShot: p38 MAPK substrates.

Trempolec N, Dave-Coll N, Nebreda AR.

Cell. 2013 Feb 14;152(4):924-924.e1. doi: 10.1016/j.cell.2013.01.047. No abstract available.

PMID:
23415236
[PubMed - indexed for MEDLINE]
Free Article
8.

SnapShot: p38 MAPK signaling.

Trempolec N, Dave-Coll N, Nebreda AR.

Cell. 2013 Jan 31;152(3):656-656.e1. doi: 10.1016/j.cell.2013.01.029. No abstract available.

PMID:
23374355
[PubMed - indexed for MEDLINE]
Free Article
9.

Liver-specific p38α deficiency causes reduced cell growth and cytokinesis failure during chronic biliary cirrhosis in mice.

Tormos AM, Arduini A, Talens-Visconti R, del Barco Barrantes I, Nebreda AR, Sastre J.

Hepatology. 2013 May;57(5):1950-61. doi: 10.1002/hep.26174. Epub 2013 Jan 25.

PMID:
23354775
[PubMed - indexed for MEDLINE]
10.

Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression.

Warr N, Carre GA, Siggers P, Faleato JV, Brixey R, Pope M, Bogani D, Childers M, Wells S, Scudamore CL, Tedesco M, del Barco Barrantes I, Nebreda AR, Trainor PA, Greenfield A.

Dev Cell. 2012 Nov 13;23(5):1020-31. doi: 10.1016/j.devcel.2012.09.016. Epub 2012 Oct 25.

PMID:
23102580
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The stress-activated protein kinases p38α/β and JNK1/2 cooperate with Chk1 to inhibit mitotic entry upon DNA replication arrest.

Llopis A, Salvador N, Ercilla A, Guaita-Esteruelas S, Barrantes Idel B, Gupta J, Gaestel M, Davis RJ, Nebreda AR, Agell N.

Cell Cycle. 2012 Oct 1;11(19):3627-37. doi: 10.4161/cc.21917. Epub 2012 Aug 30.

PMID:
22935704
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Met acts through Abl to regulate p53 transcriptional outcomes and cell survival in the developing liver.

Furlan A, Lamballe F, Stagni V, Hussain A, Richelme S, Prodosmo A, Moumen A, Brun C, Del Barco Barrantes I, Arthur JS, Koleske AJ, Nebreda AR, Barilà D, Maina F.

J Hepatol. 2012 Dec;57(6):1292-8. doi: 10.1016/j.jhep.2012.07.044. Epub 2012 Aug 10.

PMID:
22889954
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

p38α protein negatively regulates T helper type 2 responses by orchestrating multiple T cell receptor-associated signals.

Hu P, Nebreda AR, Liu Y, Carlesso N, Kaplan M, Kapur R.

J Biol Chem. 2012 Sep 28;287(40):33215-26. Epub 2012 Aug 2.

PMID:
22859305
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The p57 CDKi integrates stress signals into cell-cycle progression to promote cell survival upon stress.

Joaquin M, Gubern A, González-Nuñez D, Josué Ruiz E, Ferreiro I, de Nadal E, Nebreda AR, Posas F.

EMBO J. 2012 Jun 29;31(13):2952-64. doi: 10.1038/emboj.2012.122. Epub 2012 May 8.

PMID:
22569127
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Genetic evidence for critical roles of P38α protein in regulating mast cell differentiation and chemotaxis through distinct mechanisms.

Hu P, Carlesso N, Xu M, Liu Y, Nebreda AR, Takemoto C, Kapur R.

J Biol Chem. 2012 Jun 8;287(24):20258-69. doi: 10.1074/jbc.M112.358119. Epub 2012 Apr 19.

PMID:
22518842
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Roles of p38 MAPKs in invasion and metastasis.

del Barco Barrantes I, Nebreda AR.

Biochem Soc Trans. 2012 Feb;40(1):79-84. doi: 10.1042/BST20110676. Review.

PMID:
22260669
[PubMed - indexed for MEDLINE]
17.

Phosphorylation of FOXO3a on Ser-7 by p38 promotes its nuclear localization in response to doxorubicin.

Ho KK, McGuire VA, Koo CY, Muir KW, de Olano N, Maifoshie E, Kelly DJ, McGovern UB, Monteiro LJ, Gomes AR, Nebreda AR, Campbell DG, Arthur JS, Lam EW.

J Biol Chem. 2012 Jan 6;287(2):1545-55. doi: 10.1074/jbc.M111.284224. Epub 2011 Nov 29.

PMID:
22128155
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Genetic analysis of specific and redundant roles for p38alpha and p38beta MAPKs during mouse development.

del Barco Barrantes I, Coya JM, Maina F, Arthur JS, Nebreda AR.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12764-9. doi: 10.1073/pnas.1015013108. Epub 2011 Jul 18.

PMID:
21768366
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Expression and functional validation of new p38α transcriptional targets in tumorigenesis.

Swat A, Dolado I, Igea A, Gomez-Lopez G, Pisano DG, Cuadrado A, Nebreda AR.

Biochem J. 2011 Mar 15;434(3):549-58. doi: 10.1042/BJ20101410.

PMID:
21226672
[PubMed - indexed for MEDLINE]
Free Article
20.

Stress induced gene expression: a direct role for MAPKAP kinases in transcriptional activation of immediate early genes.

Ronkina N, Menon MB, Schwermann J, Arthur JS, Legault H, Telliez JB, Kayyali US, Nebreda AR, Kotlyarov A, Gaestel M.

Nucleic Acids Res. 2011 Apr;39(7):2503-18. doi: 10.1093/nar/gkq1178. Epub 2010 Nov 24.

PMID:
21109534
[PubMed - indexed for MEDLINE]
Free PMC Article

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