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Results: 1 to 20 of 28

1.

Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer.

Nadauld LD, Garcia S, Natsoulis G, Bell JM, Miotke L, Hopmans ES, Xu H, Pai RK, Palm C, Regan JF, Chen H, Flaherty P, Ootani A, Zhang NR, Ford JM, Kuo CJ, Ji HP.

Genome Biol. 2014 Aug 27;15(8):428. doi: 10.1186/s13059-014-0428-9.

PMID:
25315765
[PubMed - in process]
Free PMC Article
2.

A programmable method for massively parallel targeted sequencing.

Hopmans ES, Natsoulis G, Bell JM, Grimes SM, Sieh W, Ji HP.

Nucleic Acids Res. 2014 Jun;42(10):e88. doi: 10.1093/nar/gku282. Epub 2014 Apr 29.

PMID:
24782526
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Identification of Insertion Deletion Mutations from Deep Targeted Resequencing.

Natsoulis G, Zhang N, Welch K, Bell J, Ji HP.

J Data Mining Genomics Proteomics. 2013 Jul 2;4(3). pii: 1000132.

PMID:
24511426
[PubMed]
Free PMC Article
4.

Performance comparison of whole-genome sequencing platforms.

Lam HY, Clark MJ, Chen R, Chen R, Natsoulis G, O'Huallachain M, Dewey FE, Habegger L, Ashley EA, Gerstein MB, Butte AJ, Ji HP, Snyder M.

Nat Biotechnol. 2011 Dec 18;30(1):78-82. doi: 10.1038/nbt.2065. Erratum in: Nat Biotechnol. 2012 Jun;30(6):562.

PMID:
22178993
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Targeted sequencing library preparation by genomic DNA circularization.

Myllykangas S, Natsoulis G, Bell JM, Ji HP.

BMC Biotechnol. 2011 Dec 14;11:122. doi: 10.1186/1472-6750-11-122.

PMID:
22168766
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The Human OligoGenome Resource: a database of oligonucleotide capture probes for resequencing target regions across the human genome.

Newburger DE, Natsoulis G, Grimes S, Bell JM, Davis RW, Batzoglou S, Ji HP.

Nucleic Acids Res. 2012 Jan;40(Database issue):D1137-43. doi: 10.1093/nar/gkr973. Epub 2011 Nov 18.

PMID:
22102592
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A cross-sample statistical model for SNP detection in short-read sequencing data.

Muralidharan O, Natsoulis G, Bell J, Newburger D, Xu H, Kela I, Ji H, Zhang N.

Nucleic Acids Res. 2012 Jan;40(1):e5. doi: 10.1093/nar/gkr851. Epub 2011 Nov 7.

PMID:
22064853
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Efficient targeted resequencing of human germline and cancer genomes by oligonucleotide-selective sequencing.

Myllykangas S, Buenrostro JD, Natsoulis G, Bell JM, Ji HP.

Nat Biotechnol. 2011 Oct 23;29(11):1024-7. doi: 10.1038/nbt.1996.

PMID:
22020387
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Ultrasensitive detection of rare mutations using next-generation targeted resequencing.

Flaherty P, Natsoulis G, Muralidharan O, Winters M, Buenrostro J, Bell J, Brown S, Holodniy M, Zhang N, Ji HP.

Nucleic Acids Res. 2012 Jan;40(1):e2. doi: 10.1093/nar/gkr861. Epub 2011 Oct 19.

PMID:
22013163
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A flexible approach for highly multiplexed candidate gene targeted resequencing.

Natsoulis G, Bell JM, Xu H, Buenrostro JD, Ordonez H, Grimes S, Newburger D, Jensen M, Zahn JM, Zhang N, Ji HP.

PLoS One. 2011;6(6):e21088. doi: 10.1371/journal.pone.0021088. Epub 2011 Jun 30.

PMID:
21738606
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The liver pharmacological and xenobiotic gene response repertoire.

Natsoulis G, Pearson CI, Gollub J, P Eynon B, Ferng J, Nair R, Idury R, Lee MD, Fielden MR, Brennan RJ, Roter AH, Jarnagin K.

Mol Syst Biol. 2008;4:175. doi: 10.1038/msb.2008.9. Epub 2008 Mar 25.

PMID:
18364709
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A gene expression signature that predicts the future onset of drug-induced renal tubular toxicity.

Fielden MR, Eynon BP, Natsoulis G, Jarnagin K, Banas D, Kolaja KL.

Toxicol Pathol. 2005;33(6):675-83.

PMID:
16239200
[PubMed - indexed for MEDLINE]
Free Article
13.

Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action.

Ganter B, Tugendreich S, Pearson CI, Ayanoglu E, Baumhueter S, Bostian KA, Brady L, Browne LJ, Calvin JT, Day GJ, Breckenridge N, Dunlea S, Eynon BP, Furness LM, Ferng J, Fielden MR, Fujimoto SY, Gong L, Hu C, Idury R, Judo MS, Kolaja KL, Lee MD, McSorley C, Minor JM, Nair RV, Natsoulis G, Nguyen P, Nicholson SM, Pham H, Roter AH, Sun D, Tan S, Thode S, Tolley AM, Vladimirova A, Yang J, Zhou Z, Jarnagin K.

J Biotechnol. 2005 Sep 29;119(3):219-44.

PMID:
16005536
[PubMed - indexed for MEDLINE]
14.

Classification of a large microarray data set: algorithm comparison and analysis of drug signatures.

Natsoulis G, El Ghaoui L, Lanckriet GR, Tolley AM, Leroy F, Dunlea S, Eynon BP, Pearson CI, Tugendreich S, Jarnagin K.

Genome Res. 2005 May;15(5):724-36.

PMID:
15867433
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Molecular basis for fungal selectivity of novel antimitotic compounds.

Lila T, Renau TE, Wilson L, Philips J, Natsoulis G, Cope MJ, Watkins WJ, Buysse J.

Antimicrob Agents Chemother. 2003 Jul;47(7):2273-82.

PMID:
12821479
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome.

Surosky RT, Urabe M, Godwin SG, McQuiston SA, Kurtzman GJ, Ozawa K, Natsoulis G.

J Virol. 1997 Oct;71(10):7951-9.

PMID:
9311886
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Therapeutic effect of Gag-nuclease fusion protein on retrovirus-infected cell cultures.

Schumann G, Qin L, Rein A, Natsoulis G, Boeke JD.

J Virol. 1996 Jul;70(7):4329-37.

PMID:
8676455
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Targeting foreign proteins to human immunodeficiency virus particles via fusion with Vpr and Vpx.

Wu X, Liu H, Xiao H, Kim J, Seshaiah P, Natsoulis G, Boeke JD, Hahn BH, Kappes JC.

J Virol. 1995 Jun;69(6):3389-98.

PMID:
7745685
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Targeting of a nuclease to murine leukemia virus capsids inhibits viral multiplication.

Natsoulis G, Seshaiah P, Federspiel MJ, Rein A, Hughes SH, Boeke JD.

Proc Natl Acad Sci U S A. 1995 Jan 17;92(2):364-8.

PMID:
7831291
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

SPT10 and SPT21 are required for transcription of particular histone genes in Saccharomyces cerevisiae.

Dollard C, Ricupero-Hovasse SL, Natsoulis G, Boeke JD, Winston F.

Mol Cell Biol. 1994 Aug;14(8):5223-8.

PMID:
8035801
[PubMed - indexed for MEDLINE]
Free PMC Article
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