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Behavioural and molecular endophenotypes in psychotic disorders reveal heritable abnormalities in glutamatergic neurotransmission.

Scoriels L, Salek RM, Goodby E, Grainger D, Dean AM, West JA, Griffin JL, Suckling J, Nathan PJ, Lennox BR, Murray GK, Bullmore ET, Jones PB.

Transl Psychiatry. 2015 Mar 31;5:e540. doi: 10.1038/tp.2015.26.


Phase I study of nintedanib incorporating dynamic contrast-enhanced magnetic resonance imaging in patients with advanced solid tumors.

Lee CP, Taylor NJ, Attard G, Pacey S, Nathan PD, de Bono JS, Temple G, Bell S, Stefanic M, Stopfer P, Tang A, Koh DM, Collins DJ, d'Arcy J, Padhani AR, Leach MO, Judson IR, Rustin GJ.

Oncologist. 2015 Apr;20(4):368-9. doi: 10.1634/theoncologist.2014-0250. Epub 2015 Mar 20.


Health-related quality of life impact in a randomised phase III study of the combination of dabrafenib and trametinib versus dabrafenib monotherapy in patients with BRAF V600 metastatic melanoma.

Schadendorf D, Amonkar MM, Stroyakovskiy D, Levchenko E, Gogas H, de Braud F, Grob JJ, Bondarenko I, Garbe C, Lebbe C, Larkin J, Chiarion-Sileni V, Millward M, Arance A, Mandalà M, Flaherty KT, Nathan P, Ribas A, Robert C, Casey M, DeMarini DJ, Irani JG, Aktan G, Long GV.

Eur J Cancer. 2015 May;51(7):833-40. doi: 10.1016/j.ejca.2015.03.004. Epub 2015 Mar 17.


Childhood cancer survivors: Considerations for surgeons in the transition from pediatric to adult care.

Henderson TO, Nathan PC.

Semin Pediatr Surg. 2015 Apr;24(2):93-9. doi: 10.1053/j.sempedsurg.2015.01.007. Epub 2015 Jan 9.


Recommendations for cardiomyopathy surveillance for survivors of childhood cancer: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group.

Armenian SH, Hudson MM, Mulder RL, Chen MH, Constine LS, Dwyer M, Nathan PC, Tissing WJ, Shankar S, Sieswerda E, Skinner R, Steinberger J, van Dalen EC, van der Pal H, Wallace WH, Levitt G, Kremer LC.

Lancet Oncol. 2015 Mar;16(3):e123-e136. doi: 10.1016/S1470-2045(14)70409-7. Review.


Subsequent malignant neoplasms in pediatric cancer patients treated with and without hematopoietic SCT.

Pole JD, Darmawikarta D, Gassas A, Ali M, Egler M, Greenberg ML, Doyle J, Nathan PC, Schechter T.

Bone Marrow Transplant. 2015 Feb 23. doi: 10.1038/bmt.2015.4. [Epub ahead of print]


Predictors of colorectal cancer surveillance among survivors of childhood cancer treated with radiation: A report from the Childhood Cancer Survivor Study.

Daniel CL, Kohler CL, Stratton KL, Oeffinger KC, Leisenring WM, Waterbor JW, Whelan KF, Armstrong GT, Henderson TO, Krull KR, Robison LL, Nathan PC.

Cancer. 2015 Feb 3. doi: 10.1002/cncr.29265. [Epub ahead of print]


Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers.

Shlien A, Campbell BB, de Borja R, Alexandrov LB, Merico D, Wedge D, Van Loo P, Tarpey PS, Coupland P, Behjati S, Pollett A, Lipman T, Heidari A, Deshmukh S, Avitzur N, Meier B, Gerstung M, Hong Y, Merino DM, Ramakrishna M, Remke M, Arnold R, Panigrahi GB, Thakkar NP, Hodel KP, Henninger EE, Göksenin AY, Bakry D, Charames GS, Druker H, Lerner-Ellis J, Mistry M, Dvir R, Grant R, Elhasid R, Farah R, Taylor GP, Nathan PC, Alexander S, Ben-Shachar S, Ling SC, Gallinger S, Constantini S, Dirks P, Huang A, Scherer SW, Grundy RG, Durno C, Aronson M, Gartner A, Meyn MS, Taylor MD, Pursell ZF, Pearson CE, Malkin D, Futreal PA, Stratton MR, Bouffet E, Hawkins C, Campbell PJ, Tabori U; Biallelic Mismatch Repair Deficiency Consortium.

Nat Genet. 2015 Mar;47(3):257-62. doi: 10.1038/ng.3202. Epub 2015 Feb 2.


Group metacognitive therapy for repetitive negative thinking in primary and non-primary generalized anxiety disorder: An effectiveness trial.

McEvoy PM, Erceg-Hurn DM, Anderson RA, Campbell BN, Swan A, Saulsman LM, Summers M, Nathan PR.

J Affect Disord. 2015 Apr 1;175:124-32. doi: 10.1016/j.jad.2014.12.046. Epub 2014 Dec 29.


Identifying Predictors of Longitudinal Decline in the Level of Medical Care Received by Adult Survivors of Childhood Cancer: A Report from the Childhood Cancer Survivor Study.

Casillas J, Oeffinger KC, Hudson MM, Greenberg ML, Yeazel MW, Ness KK, Henderson TO, Robison LL, Armstrong GT, Liu Q, Leisenring W, Yasui Y, Nathan PC.

Health Serv Res. 2015 Jan 20. doi: 10.1111/1475-6773.12282. [Epub ahead of print]


Effects of oxytocin on attention to emotional faces in healthy volunteers and highly socially anxious males.

Clark-Elford R, Nathan PJ, Auyeung B, Mogg K, Bradley BP, Sule A, Müller U, Dudas RB, Sahakian BJ, Baron-Cohen S.

Int J Neuropsychopharmacol. 2014 Oct 31;18(2). pii: pyu012. doi: 10.1093/ijnp/pyu012.


Age-dependent changes in health status in the Childhood Cancer Survivor cohort.

Hudson MM, Oeffinger KC, Jones K, Brinkman TM, Krull KR, Mulrooney DA, Mertens A, Castellino SM, Casillas J, Gurney JG, Nathan PC, Leisenring W, Robison LL, Ness KK.

J Clin Oncol. 2015 Feb 10;33(5):479-91. doi: 10.1200/JCO.2014.57.4863. Epub 2014 Dec 29.


Improved overall survival in melanoma with combined dabrafenib and trametinib.

Robert C, Karaszewska B, Schachter J, Rutkowski P, Mackiewicz A, Stroiakovski D, Lichinitser M, Dummer R, Grange F, Mortier L, Chiarion-Sileni V, Drucis K, Krajsova I, Hauschild A, Lorigan P, Wolter P, Long GV, Flaherty K, Nathan P, Ribas A, Martin AM, Sun P, Crist W, Legos J, Rubin SD, Little SM, Schadendorf D.

N Engl J Med. 2015 Jan 1;372(1):30-9. doi: 10.1056/NEJMoa1412690. Epub 2014 Nov 16.


The Initiative to Maximize Progress in Adolescent and Young Adult Cancer Therapy (IMPACT) Cohort Study: a population-based cohort of young Canadians with cancer.

Baxter NN, Daly C, Gupta S, Pole JD, Sutradhar R, Greenberg ML, Nathan PC.

BMC Cancer. 2014 Nov 3;14:805. doi: 10.1186/1471-2407-14-805.


Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma.

Long GV, Stroyakovskiy D, Gogas H, Levchenko E, de Braud F, Larkin J, Garbe C, Jouary T, Hauschild A, Grob JJ, Chiarion Sileni V, Lebbe C, Mandalà M, Millward M, Arance A, Bondarenko I, Haanen JB, Hansson J, Utikal J, Ferraresi V, Kovalenko N, Mohr P, Probachai V, Schadendorf D, Nathan P, Robert C, Ribas A, DeMarini DJ, Irani JG, Casey M, Ouellet D, Martin AM, Le N, Patel K, Flaherty K.

N Engl J Med. 2014 Nov 13;371(20):1877-88. doi: 10.1056/NEJMoa1406037. Epub 2014 Sep 29.


Role of the MEK inhibitor trametinib in the treatment of metastatic melanoma.

King JW, Nathan PD.

Future Oncol. 2014;10(9):1559-70. doi: 10.2217/fon.14.89.


A primary care audit of familial risk in patients with a personal history of breast cancer.

Nathan P, Ahluwalia A, Chorley W.

Fam Cancer. 2014 Dec;13(4):591-4. doi: 10.1007/s10689-014-9737-0.


NY-ESO-1 specific antibody and cellular responses in melanoma patients primed with NY-ESO-1 protein in ISCOMATRIX and boosted with recombinant NY-ESO-1 fowlpox virus.

Chen JL, Dawoodji A, Tarlton A, Gnjatic S, Tajar A, Karydis I, Browning J, Pratap S, Verfaille C, Venhaus RR, Pan L, Altman DG, Cebon JS, Old LL, Nathan P, Ottensmeier C, Middleton M, Cerundolo V.

Int J Cancer. 2015 Mar 15;136(6):E590-601. doi: 10.1002/ijc.29118. Epub 2014 Aug 14.


Interpersonal problems across restrictive and binge-purge samples: data from a community-based eating disorders clinic.

Raykos BC, McEvoy PM, Carter O, Fursland A, Nathan P.

Eat Behav. 2014 Aug;15(3):449-52. doi: 10.1016/j.eatbeh.2014.06.008. Epub 2014 Jun 21.


The development of scales to measure childhood cancer survivors' readiness for transition to long-term follow-up care as adults.

Klassen AF, Rosenberg-Yunger ZR, D'Agostino NM, Cano SJ, Barr R, Syed I, Granek L, Greenberg ML, Dix D, Nathan PC.

Health Expect. 2014 Jul 22. doi: 10.1111/hex.12241. [Epub ahead of print]

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