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Results: 1 to 20 of 284

1.

Hepatocyte-Specific Delivery of siRNAs Conjugated to Novel Non-nucleosidic Trivalent N-Acetylgalactosamine Elicits Robust Gene Silencing in Vivo.

Rajeev KG, Nair JK, Jayaraman M, Charisse K, Taneja N, O'Shea J, Willoughby JL, Yucius K, Nguyen T, Shulga-Morskaya S, Milstein S, Liebow A, Querbes W, Borodovsky A, Fitzgerald K, Maier MA, Manoharan M.

Chembiochem. 2015 Mar 18. doi: 10.1002/cbic.201500023. [Epub ahead of print]

PMID:
25786782
2.

siRNA Conjugates Carrying Sequentially Assembled Trivalent N-Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing In Vivo in Hepatocytes.

Matsuda S, Keiser K, Nair JK, Charisse K, Manoharan RM, Kretschmer P, Peng CG, V Kel'in A, Kandasamy P, Willoughby JL, Liebow A, Querbes W, Yucius K, Nguyen T, Milstein S, Maier MA, Rajeev KG, Manoharan M.

ACS Chem Biol. 2015 Mar 2. [Epub ahead of print]

PMID:
25730476
3.

Oxygen saturation index and severity of hypoxic respiratory failure.

Rawat M, Chandrasekharan PK, Williams A, Gugino S, Koenigsknecht C, Swartz D, Ma CX, Mathew B, Nair J, Lakshminrusimha S.

Neonatology. 2015;107(3):161-6.

PMID:
25592054
4.

Novel lysosome targeted molecular transporter built on a guanidinium-poly-(propylene imine) hybrid dendron for efficient delivery of doxorubicin into cancer cells.

Nair JB, Mohapatra S, Ghosh S, Maiti KK.

Chem Commun (Camb). 2015 Feb 11;51(12):2403-6. doi: 10.1039/c4cc09829c.

PMID:
25564099
5.

Multivalent N-acetylgalactosamine-conjugated siRNA localizes in hepatocytes and elicits robust RNAi-mediated gene silencing.

Nair JK, Willoughby JL, Chan A, Charisse K, Alam MR, Wang Q, Hoekstra M, Kandasamy P, Kel'in AV, Milstein S, Taneja N, O'Shea J, Shaikh S, Zhang L, van der Sluis RJ, Jung ME, Akinc A, Hutabarat R, Kuchimanchi S, Fitzgerald K, Zimmermann T, van Berkel TJ, Maier MA, Rajeev KG, Manoharan M.

J Am Chem Soc. 2014 Dec 10;136(49):16958-61. doi: 10.1021/ja505986a. Epub 2014 Dec 1.

PMID:
25434769
6.

Tracheal suctioning improves gas exchange but not hemodynamics in asphyxiated lambs with meconium aspiration.

Lakshminrusimha S, Mathew B, Nair J, Gugino SF, Koenigsknecht C, Rawat M, Nielsen L, Swartz DD.

Pediatr Res. 2015 Feb;77(2):347-55. doi: 10.1038/pr.2014.186. Epub 2014 Nov 19.

PMID:
25406897
7.

Shielding of Lipid Nanoparticles for siRNA Delivery: Impact on Physicochemical Properties, Cytokine Induction, and Efficacy.

Kumar V, Qin J, Jiang Y, Duncan RG, Brigham B, Fishman S, Nair JK, Akinc A, Barros SA, Kasperkovitz PV.

Mol Ther Nucleic Acids. 2014 Nov 18;3:e210. doi: 10.1038/mtna.2014.61.

PMID:
25405467
8.

Disseminated cryptococcosis with caverno-oesophageal fistula in a case of idiopathic CD4+ T-lymphocytopenia.

Nair JP, Athavale AU, Gawande S, Shah U, Baldi M, Gupt V, Gavali V.

J Assoc Physicians India. 2014 Jan;62(1):66-9.

PMID:
25327100
9.

Cytotoxicity studies of lycorine alkaloids of the Amaryllidaceae.

Nair JJ, van Staden J.

Nat Prod Commun. 2014 Aug;9(8):1193-210. Review.

PMID:
25233606
10.

A lysosome-targeted drug delivery system based on sorbitol backbone towards efficient cancer therapy.

Maniganda S, Sankar V, Nair JB, Raghu KG, Maiti KK.

Org Biomol Chem. 2014 Sep 14;12(34):6564-9. doi: 10.1039/c4ob01153h.

PMID:
25062087
11.

Crinane alkaloids of the amaryllidaceae with cytotoxic effects in human cervical adenocarcinoma (HeLa) cells.

Nair JJ, Rárová L, Strnad M, Bastida J, Cheesman L, van Staden J.

Nat Prod Commun. 2014 Apr;9(4):461-6.

PMID:
24868855
12.

Tree shrews (Tupaia belangeri) exhibit novelty preference in the novel location memory task with 24-h retention periods.

Nair J, Topka M, Khani A, Isenschmid M, Rainer G.

Front Psychol. 2014 Apr 14;5:303. doi: 10.3389/fpsyg.2014.00303. eCollection 2014.

13.

CD28-mediated pro-survival signaling induces chemotherapeutic resistance in multiple myeloma.

Murray ME, Gavile CM, Nair JR, Koorella C, Carlson LM, Buac D, Utley A, Chesi M, Bergsagel PL, Boise LH, Lee KP.

Blood. 2014 Jun 12;123(24):3770-9. doi: 10.1182/blood-2013-10-530964. Epub 2014 Apr 29.

PMID:
24782505
14.

Crinine-type alkaloids from Hippeastrum aulicum and H. calyptratum.

de Andrade JP, Guo Y, Font-Bardia M, Calvet T, Dutilh J, Viladomat F, Codina C, Nair JJ, Zuanazzi JA, Bastida J.

Phytochemistry. 2014 Jul;103:188-95. doi: 10.1016/j.phytochem.2014.03.007. Epub 2014 Apr 23.

PMID:
24768284
15.

Network analysis of inflammatory genes and their transcriptional regulators in coronary artery disease.

Nair J, Ghatge M, Kakkar VV, Shanker J.

PLoS One. 2014 Apr 15;9(4):e94328. doi: 10.1371/journal.pone.0094328. eCollection 2014.

16.

CELSR2-PSRC1-SORT1 gene expression and association with coronary artery disease and plasma lipid levels in an Asian Indian cohort.

Arvind P, Nair J, Jambunathan S, Kakkar VV, Shanker J.

J Cardiol. 2014 Nov;64(5):339-46. doi: 10.1016/j.jjcc.2014.02.012. Epub 2014 Mar 24.

PMID:
24674750
17.

Update on PPHN: mechanisms and treatment.

Nair J, Lakshminrusimha S.

Semin Perinatol. 2014 Mar;38(2):78-91. doi: 10.1053/j.semperi.2013.11.004.

18.

Alkaloids from Boophone haemanthoides (Amaryllidaceae).

Nair JJ, Rárová L, Strnad M, Bastidad J, van Staden J.

Nat Prod Commun. 2013 Dec;8(12):1705-10.

PMID:
24555277
19.

Strongyloides stercoralis hyperinfection syndrome in patients on prolonged steroid treatment: two case reports.

Koticha A, Kuyare S, Nair J, Athvale A, Mehta P.

J Indian Med Assoc. 2013 Apr;111(4):272-4.

PMID:
24475564
20.

Genetic analysis of the 9p21.3 CAD risk locus in Asian Indians.

Shanker J, Arvind P, Jambunathan S, Nair J, Kakkar V.

Thromb Haemost. 2014 May 5;111(5):960-9. doi: 10.1160/TH13-08-0706. Epub 2014 Jan 23.

PMID:
24452806
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