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Results: 1 to 20 of 115

1.

Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients.

Hathout Y, Marathi RL, Rayavarapu S, Zhang A, Brown KJ, Seol H, Gordish-Dressman H, Cirak S, Bello L, Nagaraju K, Partridge T, Hoffman EP, Takeda S, Mah JK, Henricson E, McDonald C.

Hum Mol Genet. 2014 Jul 15. pii: ddu366. [Epub ahead of print]

PMID:
25027324
[PubMed - as supplied by publisher]
2.

Dysferlin regulates cell membrane repair by facilitating injury-triggered acid sphingomyelinase secretion.

Defour A, Van der Meulen JH, Bhat R, Bigot A, Bashir R, Nagaraju K, Jaiswal JK.

Cell Death Dis. 2014 Jun 26;5:e1306. doi: 10.1038/cddis.2014.272.

PMID:
24967968
[PubMed - in process]
Free PMC Article
3.

Pharmacologic management of Duchenne muscular dystrophy: target identification and preclinical trials.

Kornegay JN, Spurney CF, Nghiem PP, Brinkmeyer-Langford CL, Hoffman EP, Nagaraju K.

ILAR J. 2014;55(1):119-49. doi: 10.1093/ilar/ilu011.

PMID:
24936034
[PubMed - in process]
4.

Mitotic asynchrony induces TGF-β1 secretion from airway epithelium.

Alcala SE, Benton AS, Watson AM, Kureshi S, Reeves EM, Damsker J, Wang Z, Nagaraju K, Anderson J, Williams AM, Lee AJ, Hayes K, Rose MC, Hoffman EP, Freishtat RJ.

Am J Respir Cell Mol Biol. 2014 Mar 26. [Epub ahead of print]

PMID:
24669775
[PubMed - as supplied by publisher]
5.

Synthesis, docking and evaluation of antioxidant and antimicrobial activities of novel 1,2,4-triazolo[3,4-b][1,3,4]thiadiazol-6-yl)selenopheno[2,3-d]pyrimidines.

Kotaiah Y, Nagaraju K, Harikrishna N, Venkata Rao C, Yamini L, Vijjulatha M.

Eur J Med Chem. 2014 Mar 21;75:195-202. doi: 10.1016/j.ejmech.2014.01.006. Epub 2014 Jan 22.

PMID:
24531232
[PubMed - in process]
6.

Long-term treatment with naproxcinod significantly improves skeletal and cardiac disease phenotype in the mdx mouse model of dystrophy.

Uaesoontrachoon K, Quinn JL, Tatem KS, Van Der Meulen JH, Yu Q, Phadke A, Miller BK, Gordish-Dressman H, Ongini E, Miglietta D, Nagaraju K.

Hum Mol Genet. 2014 Jun 15;23(12):3239-49. doi: 10.1093/hmg/ddu033. Epub 2014 Jan 23.

PMID:
24463621
[PubMed - in process]
7.

The protein phosphatase 2A B56γ regulatory subunit is required for heart development.

Varadkar P, Despres D, Kraman M, Lozier J, Phadke A, Nagaraju K, Mccright B.

Dev Dyn. 2014 Jun;243(6):778-90. doi: 10.1002/dvdy.24111. Epub 2014 Feb 18.

PMID:
24425002
[PubMed - in process]
8.

Role of Toll-like receptors in the pathogenesis of dystrophin-deficient skeletal and heart muscle.

Henriques-Pons A, Yu Q, Rayavarapu S, Cohen TV, Ampong B, Cha HJ, Jahnke V, Van der Meulen J, Wang D, Jiang W, Kandimalla ER, Agrawal S, Spurney CF, Nagaraju K.

Hum Mol Genet. 2014 May 15;23(10):2604-17. doi: 10.1093/hmg/ddt656. Epub 2013 Dec 23.

PMID:
24368419
[PubMed - in process]
9.

Effects of Dantrolene Therapy on Disease Phenotype in Dystrophin Deficient mdx Mice.

Quinn JL, Huynh T, Uaesoontrachoon K, Tatem K, Phadke A, Van der Meulen JH, Yu Q, Nagaraju K.

PLoS Curr. 2013 Nov 8;5. pii: ecurrents.md.e246cf493a7edb1669f42fb735936b46. doi: 10.1371/currents.md.e246cf493a7edb1669f42fb735936b46.

PMID:
24270550
[PubMed]
Free PMC Article
10.

Activation of the ubiquitin proteasome pathway in a mouse model of inflammatory myopathy: a potential therapeutic target.

Rayavarapu S, Coley W, Van der Meulen JH, Cakir E, Tappeta K, Kinder TB, Dillingham BC, Brown KJ, Hathout Y, Nagaraju K.

Arthritis Rheum. 2013 Dec;65(12):3248-58. doi: 10.1002/art.38180.

PMID:
24022788
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects.

Heier CR, Damsker JM, Yu Q, Dillingham BC, Huynh T, Van der Meulen JH, Sali A, Miller BK, Phadke A, Scheffer L, Quinn J, Tatem K, Jordan S, Dadgar S, Rodriguez OC, Albanese C, Calhoun M, Gordish-Dressman H, Jaiswal JK, Connor EM, McCall JM, Hoffman EP, Reeves EK, Nagaraju K.

EMBO Mol Med. 2013 Oct;5(10):1569-85. doi: 10.1002/emmm.201302621. Epub 2013 Sep 9.

PMID:
24014378
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The effects of MyD88 deficiency on disease phenotype in dysferlin-deficient A/J mice: role of endogenous TLR ligands.

Uaesoontrachoon K, Cha HJ, Ampong B, Sali A, Vandermeulen J, Wei B, Creeden B, Huynh T, Quinn J, Tatem K, Rayavarapu S, Hoffman EP, Nagaraju K.

J Pathol. 2013 Oct;231(2):199-209. doi: 10.1002/path.4207.

PMID:
23857504
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Cowden syndrome- Clinico-radiological illustration of a rare case.

Patil PB, Sreenivasan V, Goel S, Nagaraju K, Vashishth S, Gupta S, Garg K.

Contemp Clin Dent. 2013 Jan;4(1):119-23. doi: 10.4103/0976-237X.111634.

PMID:
23853470
[PubMed]
Free PMC Article
14.

The proton pump inhibitor lansoprazole improves the skeletal phenotype in dystrophin deficient mdx mice.

Sali A, Many GM, Gordish-Dressman H, van der Meulen JH, Phadke A, Spurney CF, Cnaan A, Hoffman EP, Nagaraju K.

PLoS One. 2013 Jul 2;8(7):e66617. doi: 10.1371/journal.pone.0066617. Print 2013.

PMID:
23843959
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Selective modulation through the glucocorticoid receptor ameliorates muscle pathology in mdx mice.

Huynh T, Uaesoontrachoon K, Quinn JL, Tatem KS, Heier CR, Van Der Meulen JH, Yu Q, Harris M, Nolan CJ, Haegeman G, Grounds MD, Nagaraju K.

J Pathol. 2013 Oct;231(2):223-35. doi: 10.1002/path.4231.

PMID:
23794417
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Daily supplementation of D-ribose shows no therapeutic benefits in the MHC-I transgenic mouse model of inflammatory myositis.

Coley W, Rayavarapu S, van der Meulen JH, Duba AS, Nagaraju K.

PLoS One. 2013 Jun 13;8(6):e65970. doi: 10.1371/journal.pone.0065970. Print 2013.

PMID:
23785461
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Omigapil treatment decreases fibrosis and improves respiratory rate in dy(2J) mouse model of congenital muscular dystrophy.

Yu Q, Sali A, Van der Meulen J, Creeden BK, Gordish-Dressman H, Rutkowski A, Rayavarapu S, Uaesoontrachoon K, Huynh T, Nagaraju K, Spurney CF.

PLoS One. 2013 Jun 6;8(6):e65468. doi: 10.1371/journal.pone.0065468. Print 2013.

PMID:
23762378
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Idiopathic inflammatory myopathies: pathogenic mechanisms of muscle weakness.

Rayavarapu S, Coley W, Kinder TB, Nagaraju K.

Skelet Muscle. 2013 Jun 7;3(1):13. doi: 10.1186/2044-5040-3-13.

PMID:
23758833
[PubMed]
Free PMC Article
19.

VBP15, a glucocorticoid analogue, is effective at reducing allergic lung inflammation in mice.

Damsker JM, Dillingham BC, Rose MC, Balsley MA, Heier CR, Watson AM, Stemmy EJ, Jurjus RA, Huynh T, Tatem K, Uaesoontrachoon K, Berry DM, Benton AS, Freishtat RJ, Hoffman EP, McCall JM, Gordish-Dressman H, Constant SL, Reeves EK, Nagaraju K.

PLoS One. 2013 May 7;8(5):e63871. doi: 10.1371/journal.pone.0063871. Print 2013.

PMID:
23667681
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Accurate Quantitation of Dystrophin Protein in Human Skeletal Muscle Using Mass Spectrometry.

Brown KJ, Marathi R, Fiorillo AA, Ciccimaro EF, Sharma S, Rowlands DS, Rayavarapu S, Nagaraju K, Hoffman EP, Hathout Y.

J Bioanal Biomed. 2012 Dec 18;Suppl 7. pii: 001.

PMID:
23646235
[PubMed]
Free PMC Article

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