Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 49

1.

UVA Light-excited Kynurenines Oxidize Ascorbate and Modify Lens Proteins through the Formation of Advanced Glycation End Products: IMPLICATIONS FOR HUMAN LENS AGING AND CATARACT FORMATION.

Linetsky M, Raghavan CT, Johar K, Fan X, Monnier VM, Vasavada AR, Nagaraj RH.

J Biol Chem. 2014 Jun 13;289(24):17111-23. doi: 10.1074/jbc.M114.554410. Epub 2014 May 5.

PMID:
24798334
[PubMed - in process]
2.

Pro-inflammatory cytokines downregulate Hsp27 and cause apoptosis of human retinal capillary endothelial cells.

Nahomi RB, Palmer A, Green KM, Fort PE, Nagaraj RH.

Biochim Biophys Acta. 2014 Feb;1842(2):164-74. doi: 10.1016/j.bbadis.2013.11.011. Epub 2013 Nov 16.

PMID:
24252613
[PubMed - indexed for MEDLINE]
3.

Acetylation of lysine 92 improves the chaperone and anti-apoptotic activities of human αB-crystallin.

Nahomi RB, Huang R, Nandi SK, Wang B, Padmanabha S, Santhoshkumar P, Filipek S, Biswas A, Nagaraj RH.

Biochemistry. 2013 Nov 12;52(45):8126-38. doi: 10.1021/bi400638s. Epub 2013 Oct 28.

PMID:
24128140
[PubMed - indexed for MEDLINE]
4.

Chaperone peptides of α-crystallin inhibit epithelial cell apoptosis, protein insolubilization, and opacification in experimental cataracts.

Nahomi RB, Wang B, Raghavan CT, Voss O, Doseff AI, Santhoshkumar P, Nagaraj RH.

J Biol Chem. 2013 May 3;288(18):13022-35. doi: 10.1074/jbc.M112.440214. Epub 2013 Mar 18.

PMID:
23508955
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The combined effect of acetylation and glycation on the chaperone and anti-apoptotic functions of human α-crystallin.

Nahomi RB, Oya-Ito T, Nagaraj RH.

Biochim Biophys Acta. 2013 Jan;1832(1):195-203. doi: 10.1016/j.bbadis.2012.08.015. Epub 2012 Sep 8.

PMID:
22982407
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Antibody-mediated retinal pericyte injury: implications for diabetic retinopathy.

Li Y, Smith D, Li Q, Sheibani N, Huang S, Kern T, Nagaraj RH, Lin F.

Invest Ophthalmol Vis Sci. 2012 Aug 13;53(9):5520-6. doi: 10.1167/iovs.12-10010.

PMID:
22786897
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Hydroimidazolone modification of the conserved Arg12 in small heat shock proteins: studies on the structure and chaperone function using mutant mimics.

Nagaraj RH, Panda AK, Shanthakumar S, Santhoshkumar P, Pasupuleti N, Wang B, Biswas A.

PLoS One. 2012;7(1):e30257. doi: 10.1371/journal.pone.0030257. Epub 2012 Jan 17.

PMID:
22272318
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Acetylation of αA-crystallin in the human lens: effects on structure and chaperone function.

Nagaraj RH, Nahomi RB, Shanthakumar S, Linetsky M, Padmanabha S, Pasupuleti N, Wang B, Santhoshkumar P, Panda AK, Biswas A.

Biochim Biophys Acta. 2012 Feb;1822(2):120-9. doi: 10.1016/j.bbadis.2011.11.011. Epub 2011 Nov 18.

PMID:
22120592
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in nondiabetics).

Uchiki T, Weikel KA, Jiao W, Shang F, Caceres A, Pawlak D, Handa JT, Brownlee M, Nagaraj R, Taylor A.

Aging Cell. 2012 Feb;11(1):1-13. doi: 10.1111/j.1474-9726.2011.00752.x. Epub 2011 Nov 15.

PMID:
21967227
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Determination of dideoxyosone precursors of AGEs in human lens proteins.

Linetsky M, Kaid Johar SR, Meltretter J, Padmanabha S, Parmar T, Vasavada AR, Pischetsrieder M, Nagaraj RH.

Arch Biochem Biophys. 2011 Oct;514(1-2):16-26. doi: 10.1016/j.abb.2011.07.012. Epub 2011 Jul 28.

PMID:
21820400
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

New horizons in research on diabetic complications of the eye: special emphasis on diabetic cataracts and retinopathy.

Hegde KR, Kowluru RA, Mohr S, Nagaraj RH, Petrash JM.

J Ophthalmol. 2010;2010:979040. doi: 10.1155/2010/979040. Epub 2010 Oct 20. No abstract available.

PMID:
21049002
[PubMed]
Free PMC Article
12.

The pathogenic role of Maillard reaction in the aging eye.

Nagaraj RH, Linetsky M, Stitt AW.

Amino Acids. 2012 Apr;42(4):1205-20. doi: 10.1007/s00726-010-0778-x. Epub 2010 Oct 21. Review.

PMID:
20963455
[PubMed - indexed for MEDLINE]
13.

Candesartan attenuates diabetic retinal vascular pathology by restoring glyoxalase-I function.

Miller AG, Tan G, Binger KJ, Pickering RJ, Thomas MC, Nagaraj RH, Cooper ME, Wilkinson-Berka JL.

Diabetes. 2010 Dec;59(12):3208-15. doi: 10.2337/db10-0552. Epub 2010 Sep 17.

PMID:
20852029
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Inhibition of methylglyoxal-mediated protein modification in glyoxalase I overexpressing mouse lenses.

Gangadhariah MH, Mailankot M, Reneker L, Nagaraj RH.

J Ophthalmol. 2010;2010:274317. doi: 10.1155/2010/274317. Epub 2010 Jul 5.

PMID:
20671953
[PubMed]
Free PMC Article
15.

Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease.

Bonda DJ, Mailankot M, Stone JG, Garrett MR, Staniszewska M, Castellani RJ, Siedlak SL, Zhu X, Lee HG, Perry G, Nagaraj RH, Smith MA.

Redox Rep. 2010;15(4):161-8. doi: 10.1179/174329210X12650506623645.

PMID:
20663292
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Kynurenine inhibits fibroblast growth factor 2-mediated expression of crystallins and MIP26 in lens epithelial cells.

Mailankot M, Howell S, Nagaraj RH.

Biochim Biophys Acta. 2010 Jul-Aug;1802(7-8):609-20. doi: 10.1016/j.bbadis.2010.05.005. Epub 2010 May 15.

PMID:
20478381
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Induction of indoleamine 2,3-dioxygenase by interferon-gamma in human lens epithelial cells: apoptosis through the formation of 3-hydroxykynurenine.

Mailankot M, Nagaraj RH.

Int J Biochem Cell Biol. 2010 Sep;42(9):1446-54. doi: 10.1016/j.biocel.2010.04.014. Epub 2010 May 6.

PMID:
20435158
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The role of the cysteine residue in the chaperone and anti-apoptotic functions of human Hsp27.

Pasupuleti N, Gangadhariah M, Padmanabha S, Santhoshkumar P, Nagaraj RH.

J Cell Biochem. 2010 May 15;110(2):408-19. doi: 10.1002/jcb.22552.

PMID:
20225272
[PubMed - indexed for MEDLINE]
19.

Hydroimidazolone modification of human alphaA-crystallin: Effect on the chaperone function and protein refolding ability.

Gangadhariah MH, Wang B, Linetsky M, Henning C, Spanneberg R, Glomb MA, Nagaraj RH.

Biochim Biophys Acta. 2010 Apr;1802(4):432-41. doi: 10.1016/j.bbadis.2010.01.010. Epub 2010 Jan 18.

PMID:
20085807
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Modulation of advanced glycation endproduct synthesis by kynurenines in human lens proteins.

Nagaraj RH, Padmanabha S, Mailankot M, Staniszewska M, Mun LJ, Glomb MA, Linetsky MD.

Biochim Biophys Acta. 2010 Apr;1804(4):829-38. doi: 10.1016/j.bbapap.2009.12.008. Epub 2009 Dec 22.

PMID:
20026434
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Loading ...
Write to the Help Desk