Pyrrolo[1,2-a][1,4]benzodiazepine: a novel class of non-azole anti-dermatophyte anti-fungal agents.
Meerpoel L, Van Gestel J, Van Gerven F, Woestenborghs F, Marichal P, Sipido V, Terence G, Nash R, Corens D, Richards RD.
Meerpoel L, et al.
Bioorg Med Chem Lett. 2005 Jul 15;15(14):3453-8. doi: 10.1016/j.bmcl.2005.05.007.
Bioorg Med Chem Lett. 2005.
PMID: 15950472
The anti-fungal structure-activity relationship of this novel class of 5,6-dihydro-4H-pyrrolo[1,2-a][1,4]benzodiazepines is described together with its mode of action that appeared to be the inhibition of squalene epoxidase. ...
The anti-fungal structure-activity relationship of this novel class of 5,6-dihydro-4H-pyrrolo[1,2-a][1,4]benzodiazepines is de …