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The following term was not found in PubMed: 3-imidazol-1-ylpropyl
Page 1
N-(2-Meth-oxy-benz-yl)-9-(oxolan-2-yl)-9H-purin-6-amine.
Trávníček Z, Popa I, Dvořák Z, Starha P. Trávníček Z, et al. Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 23;69(Pt 4):o588. doi: 10.1107/S1600536813007721. Print 2013 Apr 1. Acta Crystallogr Sect E Struct Rep Online. 2013. PMID: 23634119 Free PMC article.
The purine and benzene rings subtend a dihedral angle of 66.70 (3). In the crystal, pairs of N-HN hydrogen bonds connect adjacent mol-ecules into inversion dimers. ...
The purine and benzene rings subtend a dihedral angle of 66.70 (3). In the crystal, pairs of N-HN hydrogen bonds connect adjacent mol …
N-Benzyl-9-isopropyl-9H-purin-6-amine.
Gergela D, Rouchal M, Bartoš P, Vícha R. Gergela D, et al. Acta Crystallogr Sect E Struct Rep Online. 2013 May 25;69(Pt 6):o954-5. doi: 10.1107/S1600536813013500. Print 2013 Jun 1. Acta Crystallogr Sect E Struct Rep Online. 2013. PMID: 23795114 Free PMC article.
The mol-ecules within the asymmetric unit are linked into dimers by pairs of N-HN hydrogen bonds. Weak C-Hpi contacts and pi-pi inter-actions [centroid-centroid = 3.3071 (1) A] further connect the mol-ecules into a three-dimensional network....
The mol-ecules within the asymmetric unit are linked into dimers by pairs of N-HN hydrogen bonds. Weak C-Hpi contacts and pi-pi inter …
2-Chloro-N-ethyl-9-isopropyl-9H-purin-6-amine.
Giovagnoli FA, Rouchal M, Bartoš P, Vícha R. Giovagnoli FA, et al. Acta Crystallogr Sect E Struct Rep Online. 2012 Sep 1;68(Pt 9):o2759. doi: 10.1107/S1600536812035933. Epub 2012 Aug 23. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 22969640 Free PMC article.
In the title compound, C(10)H(14)ClN(5), the purine ring system is essentially planar, with an r.m.s. deviation from the least-squares plane defined by the nine constituent atoms of 0.0063 (11) A. In the crystal, mol-ecules are linked by weak N-HN and C-Hpi inter-actions.. …
In the title compound, C(10)H(14)ClN(5), the purine ring system is essentially planar, with an r.m.s. deviation from the least-squares plane …
2-Chloro-9-isopropyl-N,N-dimethyl-9H-purin-6-amine.
Rouchal M, Nečas M, Vícha R. Rouchal M, et al. Acta Crystallogr Sect E Struct Rep Online. 2010 Apr 2;66(Pt 5):o1016. doi: 10.1107/S1600536810011797. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21579080 Free PMC article.
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs.
Eschweiler S, Ramírez-Suástegui C, Li Y, King E, Chudley L, Thomas J, Wood O, von Witzleben A, Jeffrey D, McCann K, Simon H, Mondal M, Wang A, Dicker M, Lopez-Guadamillas E, Chou TF, Dobbs NA, Essame L, Acton G, Kelly F, Halbert G, Sacco JJ, Schache AG, Shaw R, McCaul JA, Paterson C, Davies JH, Brennan PA, Singh RP, Loadman PM, Wilson W, Hackshaw A, Seumois G, Okkenhaug K, Thomas GJ, Jones TM, Ay F, Friberg G, Kronenberg M, Vanhaesebroeck B, Vijayanand P, Ottensmeier CH. Eschweiler S, et al. Nature. 2022 May;605(7911):741-746. doi: 10.1038/s41586-022-04685-2. Epub 2022 May 4. Nature. 2022. PMID: 35508656 Free PMC article. Clinical Trial.
Characterization of the relaxant response to N,N'-dipropyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine in porcine coronary arteries.
Moritz A, Gust R, Pertz HH. Moritz A, et al. J Pharmacol Exp Ther. 2007 May;321(2):699-706. doi: 10.1124/jpet.107.120337. Epub 2007 Feb 22. J Pharmacol Exp Ther. 2007. PMID: 17322023
N,N'-Dialkyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamines show structural analogy with estrogens and selective estrogen receptor modulators. ...Furthermore, the vasodilatory effect of 8 was unaffected by the adenylyl cyclase inhibitor SQ 22536 [9-(tetrahydr …
N,N'-Dialkyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamines show structural analogy with estrogens and selective estrog …
Synthesis and antimicrobial activities of N(6)-hydroxyagelasine analogs and revision of the structure of ageloximes.
Paulsen B, Fredriksen KA, Petersen D, Maes L, Matheeussen A, Naemi AO, Scheie AA, Simm R, Ma R, Wan B, Franzblau S, Gundersen LL. Paulsen B, et al. Bioorg Med Chem. 2019 Feb 15;27(4):620-629. doi: 10.1016/j.bmc.2019.01.002. Epub 2019 Jan 4. Bioorg Med Chem. 2019. PMID: 30638761 Free article.
(+)-N(6)-Hydroxyagelasine D, the enantiomer of the proposed structure of (-)-ageloxime D, as well as N(6)-hydroxyagelasine analogs were synthesized by selective N-7 alkylation of N(6)-[tert-butyl(dimethyl)silyloxy]-9-methyl-9H-purin-6 …
(+)-N(6)-Hydroxyagelasine D, the enantiomer of the proposed structure of (-)-ageloxime D, as well as N(6)-hydroxyagelasine ana …
Discovery and in vivo evaluation of (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and related PI3Kdelta inhibitors for inflammation and autoimmune disease.
Cushing TD, Hao X, Shin Y, Andrews K, Brown M, Cardozo M, Chen Y, Duquette J, Fisher B, Gonzalez-Lopez de Turiso F, He X, Henne KR, Hu YL, Hungate R, Johnson MG, Kelly RC, Lucas B, McCarter JD, McGee LR, Medina JC, San Miguel T, Mohn D, Pattaropong V, Pettus LH, Reichelt A, Rzasa RM, Seganish J, Tasker AS, Wahl RC, Wannberg S, Whittington DA, Whoriskey J, Yu G, Zalameda L, Zhang D, Metz DP. Cushing TD, et al. J Med Chem. 2015 Jan 8;58(1):480-511. doi: 10.1021/jm501624r. Epub 2014 Dec 3. J Med Chem. 2015. PMID: 25469863
Three new alkaloids isolated from the stem tuber of Pinellia pedatisecta.
DU J, Ding J, Mu ZQ, Guan SH, Cheng CR, Liu X, Guo DA. DU J, et al. Chin J Nat Med. 2018 Feb;16(2):139-142. doi: 10.1016/S1875-5364(18)30040-2. Chin J Nat Med. 2018. PMID: 29455729
Three new alkaloids (compounds 1, 2, and 3) were obtained and identified as 9-((5-methoxypyridin-2-yl)methyl)-9H-purin-6-amine (1), 4-(2-(2, 5-dioxopyrrolidin-1-yl)ethyl)phenyl acetate (2), and N-(9-((5-methoxypyridin-2-yl)methyl)-9H-purin-6-yl) …
Three new alkaloids (compounds 1, 2, and 3) were obtained and identified as 9-((5-methoxypyridin-2-yl)methyl)-9H-purin-6 …
Microwave-assisted one step synthesis of 8-arylmethyl-9H-purin-6-amines.
Tao H, Kang Y, Taldone T, Chiosis G. Tao H, et al. Bioorg Med Chem Lett. 2009 Jan 15;19(2):415-7. doi: 10.1016/j.bmcl.2008.11.057. Epub 2008 Nov 20. Bioorg Med Chem Lett. 2009. PMID: 19058963 Free PMC article.
Among small molecule Hsp90 inhibitors with clinical applicability are derivatives of 8-arylmethyl-9H-purin-6-amine class. Here we report the use of microwave-assisted chemistry for the successful one-pot delivery of 8-arylmethyl-9H-purin-6-amines. We d …
Among small molecule Hsp90 inhibitors with clinical applicability are derivatives of 8-arylmethyl-9H-purin-6-amine …
42 results