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Mutations in BRAF correlate with poor survival of colorectal cancers in Chinese population.
Liou JM, Wu MS, Shun CT, Chiu HM, Chen MJ, Chen CC, Wang HP, Lin JT, Liang JT. Liou JM, et al. Int J Colorectal Dis. 2011 Nov;26(11):1387-95. doi: 10.1007/s00384-011-1229-1. Epub 2011 May 7. Int J Colorectal Dis. 2011. PMID: 21553007
Moreover, few data were available in Chinese. Therefore, we aimed to evaluate the impact of KRAS and BRAF mutations on the survival of Chinese CRC patients. ...CONCLUSION: BRAF mutations, but not KRAS mutations, were associa …
Moreover, few data were available in Chinese. Therefore, we aimed to evaluate the impact of KRAS and BRAF mutations on …
Genetic alteration of Chinese patients with rectal mucosal melanoma.
Li H, Yang L, Lai Y, Wang X, Han X, Liu S, Wang D, Li X, Hu N, Kong Y, Si L, Li Z. Li H, et al. BMC Cancer. 2021 May 27;21(1):623. doi: 10.1186/s12885-021-08383-6. BMC Cancer. 2021. PMID: 34044811 Free PMC article.
RESULTS: BRAF mutations, NRG1 deletions and mitotic index were significant prognostic factors in the univariate analysis. ...Our study indicates that BRAF and NRG1 were correlated with a poor prognostic of RMM and may be potential therapeutic ta …
RESULTS: BRAF mutations, NRG1 deletions and mitotic index were significant prognostic factors in the univariate analysis. ...O …
Gene mutation profiling in Chinese colorectal cancer patients and its association with clinicopathological characteristics and prognosis.
Ye ZL, Qiu MZ, Tang T, Wang F, Zhou YX, Lei MJ, Guan WL, He CY. Ye ZL, et al. Cancer Med. 2020 Jan;9(2):745-756. doi: 10.1002/cam4.2727. Epub 2019 Nov 28. Cancer Med. 2020. PMID: 31782259 Free PMC article.
But BRAF mutation was associated with poor prognosis in patients who accepted anti-EGFR therapy. CONCLUSIONS: The molecular testing offered the clinical data and mutation profile of Chinese CRC patients. The information of these mutated g …
But BRAF mutation was associated with poor prognosis in patients who accepted anti-EGFR therapy. CONCLUSIONS: The molec …
Association of rs2282679 A>C polymorphism in vitamin D binding protein gene with colorectal cancer risk and survival: effect modification by dietary vitamin D intake.
Zhu Y, Wang PP, Zhai G, Bapat B, Savas S, Woodrow JR, Campbell PT, Li Y, Yang N, Zhou X, Dicks E, Mclaughlin JR, Parfrey PS. Zhu Y, et al. BMC Cancer. 2018 Feb 6;18(1):155. doi: 10.1186/s12885-018-4026-1. BMC Cancer. 2018. PMID: 29409465 Free PMC article.
Survival analyses showed that the C allele was correlated with poor DFS (per-allele HR, 1.36; 95%CI, 1.05-1.77). ...CONCLUSION: The rs2282679 SNP was not associated with overall CRC risk, but may be associated with survival after cancer diagnosis. The …
Survival analyses showed that the C allele was correlated with poor DFS (per-allele HR, 1.36; 95%CI, 1.05-1.77). ...CON …