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Results: 1 to 20 of 187

1.

The core spliceosome as target and effector of non-canonical ATM signalling.

Tresini M, Warmerdam DO, Kolovos P, Snijder L, Vrouwe MG, Demmers JA, van IJcken WF, Grosveld FG, Medema RH, Hoeijmakers JH, Mullenders LH, Vermeulen W, Marteijn JA.

Nature. 2015 Jul 2;523(7558):53-8. doi: 10.1038/nature14512. Epub 2015 Jun 24.

PMID:
26106861
2.

The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80.

Typas D, Luijsterburg MS, Wiegant WW, Diakatou M, Helfricht A, Thijssen PE, van de Broek B, Mullenders LH, van Attikum H.

Nucleic Acids Res. 2015 Jun 22. pii: gkv613. [Epub ahead of print]

3.

The E3 ubiquitin ligase ARIH1 protects against genotoxic stress by initiating a 4EHP-mediated mRNA translation arrest.

von Stechow L, Typas D, Carreras Puigvert J, Oort L, Siddappa R, Pines A, Vrieling H, van de Water B, Mullenders LH, Danen EH.

Mol Cell Biol. 2015 Apr;35(7):1254-68. doi: 10.1128/MCB.01152-14. Epub 2015 Jan 26.

PMID:
25624349
4.

Insight in the multilevel regulation of NER.

Dijk M, Typas D, Mullenders L, Pines A.

Exp Cell Res. 2014 Nov 15;329(1):116-23. doi: 10.1016/j.yexcr.2014.08.010. Epub 2014 Aug 13. Review.

PMID:
25128816
5.

Persistently stalled replication forks inhibit nucleotide excision repair in trans by sequestering Replication protein A.

Tsaalbi-Shtylik A, Moser J, Mullenders LH, Jansen JG, de Wind N.

Nucleic Acids Res. 2014 Apr;42(7):4406-13. doi: 10.1093/nar/gkt1412. Epub 2014 Jan 23.

6.

Analysis of mutant frequencies and mutation spectra in hMTH1 knockdown TK6 cells exposed to UV radiation.

Fotouhi A, Hagos WW, Ilic M, Wojcik A, Harms-Ringdahl M, de Gruijl F, Mullenders L, Jansen JG, Haghdoost S.

Mutat Res. 2013 Nov-Dec;751-752:8-14. doi: 10.1016/j.mrfmmm.2013.10.001. Epub 2013 Oct 19.

PMID:
24144844
7.

Touching base with PARPs: moonlighting in the repair of UV lesions and double-strand breaks.

Pines A, Mullenders LH, van Attikum H, Luijsterburg MS.

Trends Biochem Sci. 2013 Jun;38(6):321-30. doi: 10.1016/j.tibs.2013.03.002. Epub 2013 Apr 4. Review.

PMID:
23562323
8.

Molecular profiling of cutaneous squamous cell carcinomas and actinic keratoses from organ transplant recipients.

Hameetman L, Commandeur S, Bavinck JN, Wisgerhof HC, de Gruijl FR, Willemze R, Mullenders L, Tensen CP, Vrieling H.

BMC Cancer. 2013 Feb 5;13:58. doi: 10.1186/1471-2407-13-58.

9.

Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells.

Carreras Puigvert J, von Stechow L, Siddappa R, Pines A, Bahjat M, Haazen LC, Olsen JV, Vrieling H, Meerman JH, Mullenders LH, van de Water B, Danen EH.

Sci Signal. 2013 Jan 22;6(259):ra5. doi: 10.1126/scisignal.2003208.

PMID:
23354688
10.

PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1.

Pines A, Vrouwe MG, Marteijn JA, Typas D, Luijsterburg MS, Cansoy M, Hensbergen P, Deelder A, de Groot A, Matsumoto S, Sugasawa K, Thoma N, Vermeulen W, Vrieling H, Mullenders L.

J Cell Biol. 2012 Oct 15;199(2):235-49. doi: 10.1083/jcb.201112132. Epub 2012 Oct 8.

11.

Effects of arsenite and UVA-1 radiation on calcineurin signaling.

Musson RE, Mullenders LH, Smit NP.

Mutat Res. 2012 Jul 1;735(1-2):32-8. doi: 10.1016/j.mrfmmm.2012.04.007. Epub 2012 May 4.

PMID:
22564430
12.

DDB2 promotes chromatin decondensation at UV-induced DNA damage.

Luijsterburg MS, Lindh M, Acs K, Vrouwe MG, Pines A, van Attikum H, Mullenders LH, Dantuma NP.

J Cell Biol. 2012 Apr 16;197(2):267-81. doi: 10.1083/jcb.201106074. Epub 2012 Apr 9.

13.

No threshold for the induction of chromosomal damage at clinically relevant low doses of X rays.

Boei JJ, Vermeulen S, Skubakova MM, Meijers M, Loenen WA, Wolterbeek R, Mullenders LH, Vrieling H, Giphart-Gassler M.

Radiat Res. 2012 May;177(5):602-13. Epub 2012 Apr 2.

PMID:
22468706
14.

Enhanced nucleotide excision repair in human fibroblasts pre-exposed to ionizing radiation.

Cramers P, Filon AR, Pines A, Kleinjans JC, Mullenders LH, van Zeeland AA.

Photochem Photobiol. 2012 Jan-Feb;88(1):147-53. doi: 10.1111/j.1751-1097.2011.01019.x. Epub 2011 Nov 17.

PMID:
22017241
15.

Global phosphoproteome profiling reveals unanticipated networks responsive to cisplatin treatment of embryonic stem cells.

Pines A, Kelstrup CD, Vrouwe MG, Puigvert JC, Typas D, Misovic B, de Groot A, von Stechow L, van de Water B, Danen EH, Vrieling H, Mullenders LH, Olsen JV.

Mol Cell Biol. 2011 Dec;31(24):4964-77. doi: 10.1128/MCB.05258-11. Epub 2011 Oct 17.

16.

The role of XPC: implications in cancer and oxidative DNA damage.

Melis JP, Luijten M, Mullenders LH, van Steeg H.

Mutat Res. 2011 Nov-Dec;728(3):107-17. doi: 10.1016/j.mrrev.2011.07.001. Epub 2011 Jul 7.

17.

DNA damage response and transcription.

Lagerwerf S, Vrouwe MG, Overmeer RM, Fousteri MI, Mullenders LH.

DNA Repair (Amst). 2011 Jul 15;10(7):743-50. doi: 10.1016/j.dnarep.2011.04.024. Epub 2011 May 31. Review.

PMID:
21622031
18.

Opposite modifying effects of HR and NHEJ deficiency on cancer risk in Ptc1 heterozygous mouse cerebellum.

Tanori M, Pasquali E, Leonardi S, Giardullo P, Di Majo V, Taccioli G, Essers J, Kanaar R, Mullenders LH, Atkinson MJ, Mancuso M, Saran A, Pazzaglia S.

Oncogene. 2011 Nov 24;30(47):4740-9. doi: 10.1038/onc.2011.178. Epub 2011 May 23.

PMID:
21602895
19.

Sensitive DsRed fluorescence-based reporter cell systems for genotoxicity and oxidative stress assessment.

Hendriks G, Atallah M, Raamsman M, Morolli B, van der Putten H, Jaadar H, Tijdens I, Esveldt-van Lange R, Mullenders L, van de Water B, Vrieling H.

Mutat Res. 2011 May 10;709-710:49-59. doi: 10.1016/j.mrfmmm.2011.02.013. Epub 2011 Mar 4.

PMID:
21382384
20.

UVA1 radiation inhibits calcineurin through oxidative damage mediated by photosensitization.

Musson RE, Hensbergen PJ, Westphal AH, Temmink WP, Deelder AM, van Pelt J, Mullenders LH, Smit NP.

Free Radic Biol Med. 2011 May 15;50(10):1392-9. doi: 10.1016/j.freeradbiomed.2011.02.019. Epub 2011 Feb 24.

PMID:
21354304
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