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Results: 1 to 20 of 32

1.

JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint response.

Chen E, Ahn JS, Massie CE, Clynes D, Godfrey AL, Li J, Park HJ, Nangalia J, Silber Y, Mullally A, Gibbons RJ, Green AR.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):15190-5. doi: 10.1073/pnas.1401873111. Epub 2014 Oct 6.

PMID:
25288776
[PubMed - in process]
2.

Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice combine to promote disease progression in myeloproliferative neoplasms.

Chen E, Schneider RK, Breyfogle LJ, Rosen EA, Poveromo L, Elf S, Ko A, Brumme K, Levine R, Ebert BL, Mullally A.

Blood. 2014 Oct 3. pii: blood-2014-04-567024. [Epub ahead of print]

PMID:
25281607
[PubMed - as supplied by publisher]
3.

Role of Casein Kinase 1A1 in the Biology and Targeted Therapy of del(5q) MDS.

Schneider RK, Ademà V, Heckl D, Järås M, Mallo M, Lord AM, Chu LP, McConkey ME, Kramann R, Mullally A, Bejar R, Solé F, Ebert BL.

Cancer Cell. 2014 Oct 13;26(4):509-20. doi: 10.1016/j.ccr.2014.08.001. Epub 2014 Sep 18.

PMID:
25242043
[PubMed - in process]
4.

Loss of function of TET2 cooperates with constitutively active KIT in murine and human models of mastocytosis.

De Vita S, Schneider RK, Garcia M, Wood J, Gavillet M, Ebert BL, Gerbaulet A, Roers A, Levine RL, Mullally A, Williams DA.

PLoS One. 2014 May 2;9(5):e96209. doi: 10.1371/journal.pone.0096209. eCollection 2014.

PMID:
24788138
[PubMed - in process]
Free PMC Article
5.

Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia.

Järås M, Miller PG, Chu LP, Puram RV, Fink EC, Schneider RK, Al-Shahrour F, Peña P, Breyfogle LJ, Hartwell KA, McConkey ME, Cowley GS, Root DE, Kharas MG, Mullally A, Ebert BL.

J Exp Med. 2014 Apr 7;211(4):605-12. doi: 10.1084/jem.20131033. Epub 2014 Mar 10.

PMID:
24616378
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A prospective cohort study of alcohol exposure in early and late pregnancy within an urban population in Ireland.

Murphy DJ, Dunney C, Mullally A, Adnan N, Fahey T, Barry J.

Int J Environ Res Public Health. 2014 Feb 17;11(2):2049-63. doi: 10.3390/ijerph110202049.

PMID:
24549147
[PubMed - in process]
Free PMC Article
7.

Sinister symbiosis: pathological hematopoietic-stromal interactions in CML.

Mullally A, Ebert BL.

Cell Stem Cell. 2013 Sep 5;13(3):257-8. doi: 10.1016/j.stem.2013.08.009.

PMID:
24012363
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Population-based study of smoking behaviour throughout pregnancy and adverse perinatal outcomes.

Murphy DJ, Dunney C, Mullally A, Adnan N, Deane R.

Int J Environ Res Public Health. 2013 Aug 27;10(9):3855-67. doi: 10.3390/ijerph10093855.

PMID:
23985771
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera.

Mullally A, Bruedigam C, Poveromo L, Heidel FH, Purdon A, Vu T, Austin R, Heckl D, Breyfogle LJ, Kuhn CP, Kalaitzidis D, Armstrong SA, Williams DA, Hill GR, Ebert BL, Lane SW.

Blood. 2013 May 2;121(18):3692-702. doi: 10.1182/blood-2012-05-432989. Epub 2013 Mar 13.

PMID:
23487027
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Behavioural change in relation to alcohol exposure in early pregnancy and impact on perinatal outcomes--a prospective cohort study.

Murphy DJ, Mullally A, Cleary BJ, Fahey T, Barry J.

BMC Pregnancy Childbirth. 2013 Jan 16;13:8. doi: 10.1186/1471-2393-13-8.

PMID:
23324650
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Myeloproliferative neoplasm animal models.

Mullally A, Lane SW, Brumme K, Ebert BL.

Hematol Oncol Clin North Am. 2012 Oct;26(5):1065-81. doi: 10.1016/j.hoc.2012.07.007. Epub 2012 Aug 21. Review.

PMID:
23009938
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Janus reveals another face: the biologic rationale for targeting Janus kinase 2 in lymphoma.

Mullally A, Ebert BL.

J Clin Oncol. 2012 Nov 20;30(33):4168-70. doi: 10.1200/JCO.2012.44.0347. Epub 2012 Sep 10. No abstract available.

PMID:
22965959
[PubMed - indexed for MEDLINE]
Free Article
13.

miR-433 is aberrantly expressed in myeloproliferative neoplasms and suppresses hematopoietic cell growth and differentiation.

Lin X, Rice KL, Buzzai M, Hexner E, Costa FF, Kilpivaara O, Mullally A, Soares MB, Ebert BL, Levine R, Licht JD.

Leukemia. 2013 Feb;27(2):344-52. doi: 10.1038/leu.2012.224. Epub 2012 Aug 6.

PMID:
22864358
[PubMed - indexed for MEDLINE]
14.

Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy.

Koppikar P, Bhagwat N, Kilpivaara O, Manshouri T, Adli M, Hricik T, Liu F, Saunders LM, Mullally A, Abdel-Wahab O, Leung L, Weinstein A, Marubayashi S, Goel A, Gönen M, Estrov Z, Ebert BL, Chiosis G, Nimer SD, Bernstein BE, Verstovsek S, Levine RL.

Nature. 2012 Sep 6;489(7414):155-9. doi: 10.1038/nature11303.

PMID:
22820254
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera.

Mullally A, Poveromo L, Schneider RK, Al-Shahrour F, Lane SW, Ebert BL.

Blood. 2012 Jul 5;120(1):166-72. doi: 10.1182/blood-2012-01-402396. Epub 2012 May 24.

PMID:
22627765
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

EXEL-8232, a small-molecule JAK2 inhibitor, effectively treats thrombocytosis and extramedullary hematopoiesis in a murine model of myeloproliferative neoplasm induced by MPLW515L.

Wernig G, Kharas MG, Mullally A, Leeman DS, Okabe R, George T, Clary DO, Gilliland DG.

Leukemia. 2012 Apr;26(4):720-7. doi: 10.1038/leu.2011.261. Epub 2011 Oct 18.

PMID:
22005786
[PubMed - indexed for MEDLINE]
17.

Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q- syndrome.

Kumar MS, Narla A, Nonami A, Mullally A, Dimitrova N, Ball B, McAuley JR, Poveromo L, Kutok JL, Galili N, Raza A, Attar E, Gilliland DG, Jacks T, Ebert BL.

Blood. 2011 Oct 27;118(17):4666-73. doi: 10.1182/blood-2010-12-324715. Epub 2011 Aug 26.

PMID:
21873545
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Prevalence, predictors and perinatal outcomes of peri-conceptional alcohol exposure--retrospective cohort study in an urban obstetric population in Ireland.

Mullally A, Cleary BJ, Barry J, Fahey TP, Murphy DJ.

BMC Pregnancy Childbirth. 2011 Apr 11;11:27. doi: 10.1186/1471-2393-11-27.

PMID:
21481224
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Mutations with epigenetic effects in myeloproliferative neoplasms and recent progress in treatment: Proceedings from the 5th International Post-ASH Symposium.

Tefferi A, Abdel-Wahab O, Cervantes F, Crispino JD, Finazzi G, Girodon F, Gisslinger H, Gotlib J, Kiladjian JJ, Levine RL, Licht JD, Mullally A, Odenike O, Pardanani A, Silver RT, Solary E, Mughal T.

Blood Cancer J. 2011 Mar 4;1:e7. doi: 10.1038/bcj.2011.4.

PMID:
23471017
[PubMed]
Free PMC Article
20.

STATistical power of clonal analysis: differential STAT1 pathway activation downstream of the JAK2V617F mutation.

Mullally A, Ebert BL.

Cancer Cell. 2010 Nov 16;18(5):405-6. doi: 10.1016/j.ccr.2010.10.037. No abstract available.

PMID:
21075304
[PubMed]
Free PMC Article

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