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Results: 1 to 20 of 23

1.

A community effort to assess and improve drug sensitivity prediction algorithms.

Costello JC, Heiser LM, Georgii E, Gönen M, Menden MP, Wang NJ, Bansal M, Ammad-Ud-Din M, Hintsanen P, Khan SA, Mpindi JP, Kallioniemi O, Honkela A, Aittokallio T, Wennerberg K; NCI DREAM Community, Collins JJ, Gallahan D, Singer D, Saez-Rodriguez J, Kaski S, Gray JW, Stolovitzky G; NCI DREAM Community.

Nat Biotechnol. 2014 Jun 1. doi: 10.1038/nbt.2877. [Epub ahead of print]

PMID:
24880487
[PubMed - as supplied by publisher]
2.

A novel transcript, VNN1-AB, as a biomarker for colorectal cancer.

Løvf M, Nome T, Bruun J, Eknaes M, Bakken AC, Mpindi JP, Kilpinen S, Rognum TO, Nesbakken A, Kallioniemi O, Lothe RA, Skotheim RI.

Int J Cancer. 2014 Nov 1;135(9):2077-84. doi: 10.1002/ijc.28855. Epub 2014 Mar 29.

PMID:
24687856
[PubMed - in process]
3.

High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells.

Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M.

PLoS One. 2013 Oct 23;8(10):e77232. doi: 10.1371/journal.pone.0077232. eCollection 2013.

PMID:
24194875
[PubMed - in process]
Free PMC Article
4.

Plasticity of blood- and lymphatic endothelial cells and marker identification.

Keuschnigg J, Karinen S, Auvinen K, Irjala H, Mpindi JP, Kallioniemi O, Hautaniemi S, Jalkanen S, Salmi M.

PLoS One. 2013 Sep 10;8(9):e74293. doi: 10.1371/journal.pone.0074293. eCollection 2013. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/cfda269a-cb46-4735-b87f-42afccb6aeb1.

PMID:
24058540
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

ARLTS1 and prostate cancer risk--analysis of expression and regulation.

Siltanen S, Fischer D, Rantapero T, Laitinen V, Mpindi JP, Kallioniemi O, Wahlfors T, Schleutker J.

PLoS One. 2013 Aug 5;8(8):e72040. doi: 10.1371/journal.pone.0072040. Print 2013.

PMID:
23940804
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

High-throughput RNAi screening for novel modulators of vimentin expression identifies MTHFD2 as a regulator of breast cancer cell migration and invasion.

Lehtinen L, Ketola K, Mäkelä R, Mpindi JP, Viitala M, Kallioniemi O, Iljin K.

Oncotarget. 2013 Jan;4(1):48-63.

PMID:
23295955
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Systemic analysis of gene expression profiles identifies ErbB3 as a potential drug target in pediatric alveolar rhabdomyosarcoma.

Nordberg J, Mpindi JP, Iljin K, Pulliainen AT, Kallajoki M, Kallioniemi O, Elenius K, Elenius V.

PLoS One. 2012;7(12):e50819. doi: 10.1371/journal.pone.0050819. Epub 2012 Dec 5.

PMID:
23227212
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ.

Jin S, Mutvei AP, Chivukula IV, Andersson ER, Ramsköld D, Sandberg R, Lee KL, Kronqvist P, Mamaeva V, Ostling P, Mpindi JP, Kallioniemi O, Screpanti I, Poellinger L, Sahlgren C, Lendahl U.

Oncogene. 2013 Oct 10;32(41):4892-902. doi: 10.1038/onc.2012.517. Epub 2012 Nov 26.

PMID:
23178494
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer.

Vainio P, Mpindi JP, Kohonen P, Fey V, Mirtti T, Alanen KA, Perälä M, Kallioniemi O, Iljin K.

PLoS One. 2012;7(6):e39801. doi: 10.1371/journal.pone.0039801. Epub 2012 Jun 28.

PMID:
22761906
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugs.

Khan SA, Faisal A, Mpindi JP, Parkkinen JA, Kalliokoski T, Poso A, Kallioniemi OP, Wennerberg K, Kaski S.

BMC Bioinformatics. 2012 May 30;13:112. doi: 10.1186/1471-2105-13-112.

PMID:
22646858
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A functional genetic screen reveals new regulators of β1-integrin activity.

Pellinen T, Rantala JK, Arjonen A, Mpindi JP, Kallioniemi O, Ivaska J.

J Cell Sci. 2012 Feb 1;125(Pt 3):649-61. doi: 10.1242/jcs.090704.

PMID:
22389402
[PubMed - indexed for MEDLINE]
Free Article
12.

CIP2A signature reveals the MYC dependency of CIP2A-regulated phenotypes and its clinical association with breast cancer subtypes.

Niemelä M, Kauko O, Sihto H, Mpindi JP, Nicorici D, Pernilä P, Kallioniemi OP, Joensuu H, Hautaniemi S, Westermarck J.

Oncogene. 2012 Sep 27;31(39):4266-78. doi: 10.1038/onc.2011.599. Epub 2012 Jan 16.

PMID:
22249265
[PubMed - indexed for MEDLINE]
13.

Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion.

Björkman M, Östling P, Härmä V, Virtanen J, Mpindi JP, Rantala J, Mirtti T, Vesterinen T, Lundin M, Sankila A, Rannikko A, Kaivanto E, Kohonen P, Kallioniemi O, Nees M.

Oncogene. 2012 Jul 19;31(29):3444-56. doi: 10.1038/onc.2011.512. Epub 2011 Nov 28.

PMID:
22120715
[PubMed - indexed for MEDLINE]
14.

Contribution of ARLTS1 Cys148Arg (T442C) variant with prostate cancer risk and ARLTS1 function in prostate cancer cells.

Siltanen S, Wahlfors T, Schindler M, Saramäki OR, Mpindi JP, Latonen L, Vessella RL, Tammela TL, Kallioniemi O, Visakorpi T, Schleutker J.

PLoS One. 2011;6(10):e26595. doi: 10.1371/journal.pone.0026595. Epub 2011 Oct 20.

PMID:
22028916
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer.

Vainio P, Wolf M, Edgren H, He T, Kohonen P, Mpindi JP, Smit F, Verhaegh G, Schalken J, Perälä M, Iljin K, Kallioniemi O.

Prostate. 2012 May 15;72(7):789-802. doi: 10.1002/pros.21487. Epub 2011 Sep 14.

PMID:
21919029
[PubMed - indexed for MEDLINE]
16.

HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferation.

Haapa-Paananen S, Kiviluoto S, Waltari M, Puputti M, Mpindi JP, Kohonen P, Tynninen O, Haapasalo H, Joensuu H, Perälä M, Kallioniemi O.

Oncogene. 2012 Mar 8;31(10):1299-310. doi: 10.1038/onc.2011.316. Epub 2011 Jul 25.

PMID:
21785461
[PubMed - indexed for MEDLINE]
17.

A cell spot microarray method for production of high density siRNA transfection microarrays.

Rantala JK, Mäkelä R, Aaltola AR, Laasola P, Mpindi JP, Nees M, Saviranta P, Kallioniemi O.

BMC Genomics. 2011 Mar 28;12:162. doi: 10.1186/1471-2164-12-162.

PMID:
21443765
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

GTI: a novel algorithm for identifying outlier gene expression profiles from integrated microarray datasets.

Mpindi JP, Sara H, Haapa-Paananen S, Kilpinen S, Pisto T, Bucher E, Ojala K, Iljin K, Vainio P, Björkman M, Gupta S, Kohonen P, Nees M, Kallioniemi O.

PLoS One. 2011 Feb 18;6(2):e17259. doi: 10.1371/journal.pone.0017259. Erratum in: PLoS One. 2011;6(4). doi:10.1371/annotation/7d571883-faf0-4f66-86a2-806c36c4741c.

PMID:
21365010
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer.

Vainio P, Gupta S, Ketola K, Mirtti T, Mpindi JP, Kohonen P, Fey V, Perälä M, Smit F, Verhaegh G, Schalken J, Alanen KA, Kallioniemi O, Iljin K.

Am J Pathol. 2011 Feb;178(2):525-36. doi: 10.1016/j.ajpath.2010.10.002.

PMID:
21281786
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer.

Vuoriluoto K, Haugen H, Kiviluoto S, Mpindi JP, Nevo J, Gjerdrum C, Tiron C, Lorens JB, Ivaska J.

Oncogene. 2011 Mar 24;30(12):1436-48. doi: 10.1038/onc.2010.509. Epub 2010 Nov 8.

PMID:
21057535
[PubMed - indexed for MEDLINE]

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