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Items: 20


Early Epigenetic Downregulation of microRNA-192 Expression Promotes Pancreatic Cancer Progression.

Botla SK, Savant S, Jandaghi P, Bauer AS, Mücke O, Moskalev EA, Neoptolemos JP, Costello E, Greenhalf W, Scarpa A, Gaida MM, Büchler MW, Strobel O, Hackert T, Giese NA, Augustin HG, Hoheisel JD.

Cancer Res. 2016 May 23. [Epub ahead of print]


NAB2-STAT6 Gene Fusion in Meningeal Hemangiopericytoma and Solitary Fibrous Tumor.

Fritchie KJ, Jin L, Rubin BP, Burger PC, Jenkins SM, Barthelmeß S, Moskalev EA, Haller F, Oliveira AM, Giannini C.

J Neuropathol Exp Neurol. 2016 Mar;75(3):263-71. doi: 10.1093/jnen/nlv026. Epub 2016 Feb 16.


Paediatric and adult soft tissue sarcomas with NTRK1 gene fusions: a subset of spindle cell sarcomas unified by a prominent myopericytic/haemangiopericytic pattern.

Haller F, Knopf J, Ackermann A, Bieg M, Kleinheinz K, Schlesner M, Moskalev EA, Will R, Satir AA, Abdelmagid IE, Giedl J, Carbon R, Rompel O, Hartmann A, Wiemann S, Metzler M, Agaimy A.

J Pathol. 2016 Apr;238(5):700-10. doi: 10.1002/path.4701.


Utility of different massive parallel sequencing platforms for mutation profiling in clinical samples and identification of pitfalls using FFPE tissue.

Fassunke J, Haller F, Hebele S, Moskalev EA, Penzel R, Pfarr N, Merkelbach-Bruse S, Endris V.

Int J Mol Med. 2015 Nov;36(5):1233-43. doi: 10.3892/ijmm.2015.2339. Epub 2015 Sep 7.


GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers.

Moskalev EA, Jandaghi P, Fallah M, Manoochehri M, Botla SK, Kolychev OV, Nikitin EA, Bubnov VV, von Knebel Doeberitz M, Strobel O, Hackert T, Büchler MW, Giese N, Bauer A, Muley T, Warth A, Schirmacher P, Haller F, Hoheisel JD, Riazalhosseini Y.

Oncotarget. 2015 Feb 28;6(6):4418-27.


Recurrent mutations within the amino-terminal region of β-catenin are probable key molecular driver events in sinonasal hemangiopericytoma.

Haller F, Bieg M, Moskalev EA, Barthelmeß S, Geddert H, Boltze C, Diessl N, Braumandl K, Brors B, Iro H, Hartmann A, Wiemann S, Agaimy A.

Am J Pathol. 2015 Feb;185(2):563-71. doi: 10.1016/j.ajpath.2014.10.019. Epub 2014 Dec 4.


Combined DNA methylation and gene expression profiling in gastrointestinal stromal tumors reveals hypomethylation of SPP1 as an independent prognostic factor.

Haller F, Zhang JD, Moskalev EA, Braun A, Otto C, Geddert H, Riazalhosseini Y, Ward A, Balwierz A, Schaefer IM, Cameron S, Ghadimi BM, Agaimy A, Fletcher JA, Hoheisel J, Hartmann A, Werner M, Wiemann S, Sahin O.

Int J Cancer. 2015 Mar 1;136(5):1013-23. doi: 10.1002/ijc.29088. Epub 2014 Aug 1.


Aberrant DNA hypermethylation of SDHC: a novel mechanism of tumor development in Carney triad.

Haller F, Moskalev EA, Faucz FR, Barthelmeß S, Wiemann S, Bieg M, Assie G, Bertherat J, Schaefer IM, Otto C, Rattenberry E, Maher ER, Ströbel P, Werner M, Carney JA, Hartmann A, Stratakis CA, Agaimy A.

Endocr Relat Cancer. 2014 Aug;21(4):567-77. doi: 10.1530/ERC-14-0254. Epub 2014 May 23.


Phenotypical and molecular distinctness of sinonasal haemangiopericytoma compared to solitary fibrous tumour of the sinonasal tract.

Agaimy A, Barthelmeß S, Geddert H, Boltze C, Moskalev EA, Koch M, Wiemann S, Hartmann A, Haller F.

Histopathology. 2014 Nov;65(5):667-73. doi: 10.1111/his.12452. Epub 2014 Aug 4.


Sensitive and specific detection of EML4-ALK rearrangements in non-small cell lung cancer (NSCLC) specimens by multiplex amplicon RNA massive parallel sequencing.

Moskalev EA, Frohnauer J, Merkelbach-Bruse S, Schildhaus HU, Dimmler A, Schubert T, Boltze C, König H, Fuchs F, Sirbu H, Rieker RJ, Agaimy A, Hartmann A, Haller F.

Lung Cancer. 2014 Jun;84(3):215-21. doi: 10.1016/j.lungcan.2014.03.002. Epub 2014 Mar 13.


Solitary fibrous tumors/hemangiopericytomas with different variants of the NAB2-STAT6 gene fusion are characterized by specific histomorphology and distinct clinicopathological features.

Barthelmeß S, Geddert H, Boltze C, Moskalev EA, Bieg M, Sirbu H, Brors B, Wiemann S, Hartmann A, Agaimy A, Haller F.

Am J Pathol. 2014 Apr;184(4):1209-18. doi: 10.1016/j.ajpath.2013.12.016. Epub 2014 Feb 8.


Mutation status of the mediator complex subunit 12 (MED12) in uterine leiomyomas and concurrent/metachronous multifocal peritoneal smooth muscle nodules (leiomyomatosis peritonealis disseminata).

Rieker RJ, Agaimy A, Moskalev EA, Hebele S, Hein A, Mehlhorn G, Beckmann MW, Hartmann A, Haller F.

Pathology. 2013 Jun;45(4):388-92. doi: 10.1097/PAT.0b013e328360bf97.


Increased detection rates of EGFR and KRAS mutations in NSCLC specimens with low tumour cell content by 454 deep sequencing.

Moskalev EA, Stöhr R, Rieker R, Hebele S, Fuchs F, Sirbu H, Mastitsky SE, Boltze C, König H, Agaimy A, Hartmann A, Haller F.

Virchows Arch. 2013 Apr;462(4):409-19. doi: 10.1007/s00428-013-1376-6. Epub 2013 Mar 7.


Diagnostic values of GHSR DNA methylation pattern in breast cancer.

Botla SK, Gholami AM, Malekpour M, Moskalev EA, Fallah M, Jandaghi P, Aghajani A, Bondar IS, Omranipour R, Malekpour F, Mohajeri A, Babadi AJ, Sahin Ö, Bubnov VV, Najmabadi H, Hoheisel JD, Riazalhosseini Y.

Breast Cancer Res Treat. 2012 Oct;135(3):705-13. doi: 10.1007/s10549-012-2197-z. Epub 2012 Aug 17.


Concurrent epigenetic silencing of wnt/β-catenin pathway inhibitor genes in B cell chronic lymphocytic leukaemia.

Moskalev EA, Luckert K, Vorobjev IA, Mastitsky SE, Gladkikh AA, Stephan A, Schrenk M, Kaplanov KD, Kalashnikova OB, Pötz O, Joos TO, Hoheisel JD.

BMC Cancer. 2012 Jun 6;12:213. doi: 10.1186/1471-2407-12-213.


RNA-directed epigenomic reprogramming: an emerging principle of a more targeted cancer therapy?

Moskalev EA, Schubert M, Hoheisel JD.

Genes Chromosomes Cancer. 2012 Feb;51(2):105-10. doi: 10.1002/gcc.20943. Epub 2011 Nov 1.


Correction of PCR-bias in quantitative DNA methylation studies by means of cubic polynomial regression.

Moskalev EA, Zavgorodnij MG, Majorova SP, Vorobjev IA, Jandaghi P, Bure IV, Hoheisel JD.

Nucleic Acids Res. 2011 Jun;39(11):e77. doi: 10.1093/nar/gkr213. Epub 2011 Apr 12.


[DNA methylation profiling in cancer: from single nucleotides towards methylome].

Moskalev EA, Eprintsev AT, Hoheisel JD.

Mol Biol (Mosk). 2007 Sep-Oct;41(5):793-807. Review. Russian.


Expression level of lipoprotein lipase and dystrophin genes predict survival in B-cell chronic lymphocytic leukemia.

Nikitin EA, Malakho SG, Biderman BV, Baranova AV, Lorie YY, Shevelev AY, Peklo MM, Vlasik TN, Moskalev EA, Zingerman BV, Vorob'ev IA, Poltaraus AB, Sudarikov AB, Vorobjev AI.

Leuk Lymphoma. 2007 May;48(5):912-22.


[Comparative analysis of the glyoxylate cycle clue enzyme isocitrate lyases from organisms of different systemic groups].

Popov VN, Moskalev EA, Shevchenko MIu, Eprintsev AT.

Zh Evol Biokhim Fiziol. 2005 Nov-Dec;41(6):507-13. Russian. No abstract available.

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