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Results: 1 to 20 of 95

1.

Rheumatoid arthritis response to treatment across IgG1 allotype - anti-TNF incompatibility: a case-only study.

Montes A, Perez-Pampin E, Navarro-Sarabia F, Moreira V, de la Serna AR, Magallares B, Vasilopoulos Y, Sarafidou T, Fernández-Nebro A, Del Carmen Ordóñez M, Narváez J, Cañete JD, Marquez A, Pascual-Salcedo D, Joven B, Carreira P, Moreno-Ramos MJ, Caliz R, Ferrer MA, Garcia-Portales R, Blanco FJ, Magro C, Raya E, Valor L, Alegre-Sancho JJ, Balsa A, Martin J, Plant D, Isaacs J, Morgan AW, Barton A, Wilson AG; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS), Gómez-Reino JJ, Gonzalez A.

Arthritis Res Ther. 2015 Mar 18;17(1):63. [Epub ahead of print]

PMID:
25885039
2.

A Large-Scale Genetic Analysis Reveals a Strong Contribution of the HLA Class II Region to Giant Cell Arteritis Susceptibility.

Carmona FD, Mackie SL, Martín JE, Taylor JC, Vaglio A, Eyre S, Bossini-Castillo L, Castañeda S, Cid MC, Hernández-Rodríguez J, Prieto-González S, Solans R, Ramentol-Sintas M, González-Escribano MF, Ortiz-Fernández L, Morado IC, Narváez J, Miranda-Filloy JA; Spanish GCA Group, Beretta L, Lunardi C, Cimmino MA, Gianfreda D, Santilli D, Ramirez GA, Soriano A, Muratore F, Pazzola G, Addimanda O, Wijmenga C, Witte T, Schirmer JH, Moosig F, Schönau V, Franke A, Palm Ø, Molberg Ø, Diamantopoulos AP, Carette S, Cuthbertson D, Forbess LJ, Hoffman GS, Khalidi NA, Koening CL, Langford CA, McAlear CA, Moreland L, Monach PA, Pagnoux C, Seo P, Spiera R, Sreih AG, Warrington KJ, Ytterberg SR, Gregersen PK, Pease CT, Gough A, Green M, Hordon L, Jarrett S, Watts R, Levy S, Patel Y, Kamath S, Dasgupta B, Worthington J, Koeleman BP, de Bakker PI, Barrett JH, Salvarani C, Merkel PA, González-Gay MA, Morgan AW, Martín J.

Am J Hum Genet. 2015 Apr 2;96(4):565-80. doi: 10.1016/j.ajhg.2015.02.009. Epub 2015 Mar 26.

PMID:
25817017
3.

Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis.

Bowes J, Budu-Aggrey A, Huffmeier U, Uebe S, Steel K, Hebert HL, Wallace C, Massey J, Bruce IN, Bluett J, Feletar M, Morgan AW, Marzo-Ortega H, Donohoe G, Morris DW, Helliwell P, Ryan AW, Kane D, Warren RB, Korendowych E, Alenius GM, Giardina E, Packham J, McManus R, FitzGerald O, McHugh N, Brown MA, Ho P, Behrens F, Burkhardt H, Reis A, Barton A.

Nat Commun. 2015 Feb 5;6:6046. doi: 10.1038/ncomms7046.

4.

Validity and reliability of the Persian version of Behçet's disease quality-of-life (BD-QoL) questionnaire: a cross-cultural adaptation.

Vojdanian M, Faezi ST, Tennant A, Morgan AW, Paragomi P, Qorbani M, Mattaji M, Davatchi F.

Rheumatol Int. 2015 Apr;35(4):677-84. doi: 10.1007/s00296-014-3128-6. Epub 2014 Sep 13.

PMID:
25216713
5.

Impact of inadequate adherence on response to subcutaneously administered anti-tumour necrosis factor drugs: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort.

Bluett J, Morgan C, Thurston L, Plant D, Hyrich KL, Morgan AW, Wilson AG, Isaacs JD, Cordingley L, Barton A; BRAGGSS.

Rheumatology (Oxford). 2015 Mar;54(3):494-9. doi: 10.1093/rheumatology/keu358. Epub 2014 Sep 10.

6.

MTHFR functional genetic variation and methotrexate treatment response in rheumatoid arthritis: a meta-analysis.

Morgan MD, Al-Shaarawy N, Martin S, Robinson JI, Twigg S; YEAR Consortium, Magdy AA, Omar AS, Ghattas MH, Emery P, Barrett JH, Morgan AW.

Pharmacogenomics. 2014 Mar;15(4):467-75. doi: 10.2217/pgs.13.235.

PMID:
24624914
7.

Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.

Orozco G, Viatte S, Bowes J, Martin P, Wilson AG, Morgan AW, Steer S, Wordsworth P, Hocking LJ; UK Rheumatoid Arthritis Genetics Consortium; Wellcome Trust Case Control Consortium; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate Consortium, Barton A, Worthington J, Eyre S.

Arthritis Rheumatol. 2014 Jan;66(1):24-30. doi: 10.1002/art.38196.

8.

Impact of psychological factors on subjective disease activity assessments in patients with severe rheumatoid arthritis.

Cordingley L, Prajapati R, Plant D, Maskell D, Morgan C, Ali FR, Morgan AW, Wilson AG, Isaacs JD; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS), Barton A.

Arthritis Care Res (Hoboken). 2014 Jun;66(6):861-8. doi: 10.1002/acr.22249.

9.

Testing the role of vitamin D in response to antitumour necrosis factor α therapy in a UK cohort: a Mendelian randomisation approach.

Yarwood A, Viatte S, Plant D, Morgan AW, Isaacs J, Wilson AG, Hyrich K, Eyre S, Barton A; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS).

Ann Rheum Dis. 2014 May;73(5):938-40. doi: 10.1136/annrheumdis-2013-204443. Epub 2013 Dec 9. No abstract available.

PMID:
24323394
10.

Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.

Scott IC, Seegobin SD, Steer S, Tan R, Forabosco P, Hinks A, Eyre S, Morgan AW, Wilson AG, Hocking LJ, Wordsworth P, Barton A, Worthington J, Cope AP, Lewis CM.

PLoS Genet. 2013;9(9):e1003808. doi: 10.1371/journal.pgen.1003808. Epub 2013 Sep 19. Erratum in: PLoS Genet. 2013 Oct;9(10). doi:10.1371/annotation/a86ab397-f58c-4144-a241-4957836a728a.

11.

Identification of BACH2 and RAD51B as rheumatoid arthritis susceptibility loci in a meta-analysis of genome-wide data.

McAllister K, Yarwood A, Bowes J, Orozco G, Viatte S, Diogo D, Hocking LJ, Steer S, Wordsworth P, Wilson AG, Morgan AW; UK Rheumatoid Arthritis Genetics Consortium; Rheumatoid Arthritis Consortium International, Kremer JM, Pappas D, Gregersen P, Klareskog L, Plenge R, Barton A, Greenberg J, Worthington J, Eyre S.

Arthritis Rheum. 2013 Dec;65(12):3058-62. doi: 10.1002/art.38183.

12.

Identification of the PTPN22 functional variant R620W as susceptibility genetic factor for giant cell arteritis.

Serrano A, Márquez A, Mackie SL, Carmona FD, Solans R, Miranda-Filloy JA, Hernández-Rodríguez J, Cid MC, Castañeda S, Morado IC, Narváez J, Blanco R, Sopeña B, García-Villanueva MJ, Monfort J, Ortego-Centeno N, Unzurrunzaga A, Marí-Alfonso B, Sánchez-Martín J, de Miguel E, Magro C, Raya E, Braun N, Latus J, Molberg O, Lie BA, Moosig F, Witte T, Morgan AW, González-Gay MA, Martín J; UK GCA Consortium Spanish GCA Consortium.

Ann Rheum Dis. 2013 Nov;72(11):1882-6. doi: 10.1136/annrheumdis-2013-203641. Epub 2013 Aug 14.

13.

Remission induction comparing infliximab and high-dose intravenous steroid, followed by treat-to-target: a double-blind, randomised, controlled trial in new-onset, treatment-naive, rheumatoid arthritis (the IDEA study).

Nam JL, Villeneuve E, Hensor EM, Conaghan PG, Keen HI, Buch MH, Gough AK, Green MJ, Helliwell PS, Keenan AM, Morgan AW, Quinn M, Reece R, van der Heijde DM, Wakefield RJ, Emery P.

Ann Rheum Dis. 2014 Jan;73(1):75-85. doi: 10.1136/annrheumdis-2013-203440. Epub 2013 Aug 2.

PMID:
23912798
14.
15.

Allele-dose association of the C5orf30 rs26232 variant with joint damage in rheumatoid arthritis.

Teare MD, Knevel R, Morgan MD, Kleszcz A, Emery P, Moore DJ, Conaghan P, Huizinga TW, Morgan AW, van der Helm-van Mil AH, Wilson AG.

Arthritis Rheum. 2013 Oct;65(10):2555-61. doi: 10.1002/art.38064.

16.

Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment.

Mathews RJ, Robinson JI, Battellino M, Wong C, Taylor JC; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS), Eyre S, Churchman SM, Wilson AG, Isaacs JD, Hyrich K, Barton A, Plant D, Savic S, Cook GP, Sarzi-Puttini P, Emery P, Barrett JH, Morgan AW, McDermott MF.

Ann Rheum Dis. 2014 Jun;73(6):1202-10. doi: 10.1136/annrheumdis-2013-203276. Epub 2013 May 17.

PMID:
23687262
17.

Metaanalysis of the association of smoking and PTPN22 R620W genotype on autoantibody status and radiological erosions in rheumatoid arthritis.

Taylor LH, Twigg S, Worthington J, Emery P, Morgan AW, Wilson AG, Teare MD.

J Rheumatol. 2013 Jul;40(7):1048-53. doi: 10.3899/jrheum.120784. Epub 2013 May 1.

PMID:
23637320
18.

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis.

Cui J, Stahl EA, Saevarsdottir S, Miceli C, Diogo D, Trynka G, Raj T, Mirkov MU, Canhao H, Ikari K, Terao C, Okada Y, Wedrén S, Askling J, Yamanaka H, Momohara S, Taniguchi A, Ohmura K, Matsuda F, Mimori T, Gupta N, Kuchroo M, Morgan AW, Isaacs JD, Wilson AG, Hyrich KL, Herenius M, Doorenspleet ME, Tak PP, Crusius JB, van der Horst-Bruinsma IE, Wolbink GJ, van Riel PL, van de Laar M, Guchelaar HJ, Shadick NA, Allaart CF, Huizinga TW, Toes RE, Kimberly RP, Bridges SL Jr, Criswell LA, Moreland LW, Fonseca JE, de Vries N, Stranger BE, De Jager PL, Raychaudhuri S, Weinblatt ME, Gregersen PK, Mariette X, Barton A, Padyukov L, Coenen MJ, Karlson EW, Plenge RM.

PLoS Genet. 2013 Mar;9(3):e1003394. doi: 10.1371/journal.pgen.1003394. Epub 2013 Mar 28.

19.

Should I send my patient with previous giant cell arteritis for imaging of the thoracic aorta? A systematic literature review and meta-analysis.

Mackie SL, Hensor EM, Morgan AW, Pease CT.

Ann Rheum Dis. 2014 Jan;73(1):143-8. doi: 10.1136/annrheumdis-2012-202145. Epub 2012 Dec 22. Review.

PMID:
23264356
20.

Informed conditioning on clinical covariates increases power in case-control association studies.

Zaitlen N, Lindström S, Pasaniuc B, Cornelis M, Genovese G, Pollack S, Barton A, Bickeböller H, Bowden DW, Eyre S, Freedman BI, Friedman DJ, Field JK, Groop L, Haugen A, Heinrich J, Henderson BE, Hicks PJ, Hocking LJ, Kolonel LN, Landi MT, Langefeld CD, Le Marchand L, Meister M, Morgan AW, Raji OY, Risch A, Rosenberger A, Scherf D, Steer S, Walshaw M, Waters KM, Wilson AG, Wordsworth P, Zienolddiny S, Tchetgen ET, Haiman C, Hunter DJ, Plenge RM, Worthington J, Christiani DC, Schaumberg DA, Chasman DI, Altshuler D, Voight B, Kraft P, Patterson N, Price AL.

PLoS Genet. 2012;8(11):e1003032. doi: 10.1371/journal.pgen.1003032. Epub 2012 Nov 8.

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