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Results: 1 to 20 of 150

1.

DNA methylation analysis of Homeobox genes implicates HOXB7 hypomethylation as risk factor for neural tube defects.

Rochtus A, Izzi B, Vangeel E, Louwette S, Wittevrongel C, Lambrechts D, Moreau Y, Winand R, Verpoorten C, Jansen K, Van Geet C, Freson K.

Epigenetics. 2015 Jan 7:0. [Epub ahead of print]

PMID:
25565354
[PubMed - as supplied by publisher]
2.

NGS-Logistics: federated analysis of NGS sequence variants across multiple locations.

Ardeshirdavani A, Souche E, Dehaspe L, Van Houdt J, Vermeesch JR, Moreau Y.

Genome Med. 2014 Sep 17;6(9):71. doi: 10.1186/s13073-014-0071-9. eCollection 2014.

PMID:
25328540
[PubMed]
Free PMC Article
3.

Effective diagnosis of genetic disease by computational phenotype analysis of the disease-associated genome.

Zemojtel T, Köhler S, Mackenroth L, Jäger M, Hecht J, Krawitz P, Graul-Neumann L, Doelken S, Ehmke N, Spielmann M, Oien NC, Schweiger MR, Krüger U, Frommer G, Fischer B, Kornak U, Flöttmann R, Ardeshirdavani A, Moreau Y, Lewis SE, Haendel M, Smedley D, Horn D, Mundlos S, Robinson PN.

Sci Transl Med. 2014 Sep 3;6(252):252ra123. doi: 10.1126/scitranslmed.3009262.

PMID:
25186178
[PubMed - in process]
4.

ECCB 2014: The 13th European Conference on Computational Biology.

Devignes MD, Moreau Y.

Bioinformatics. 2014 Sep 1;30(17):i345-8. doi: 10.1093/bioinformatics/btu512. No abstract available.

PMID:
25161218
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Protein fold recognition using geometric kernel data fusion.

Zakeri P, Jeuris B, Vandebril R, Moreau Y.

Bioinformatics. 2014 Jul 1;30(13):1850-7. doi: 10.1093/bioinformatics/btu118. Epub 2014 Mar 3.

PMID:
24590441
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

In vitro screening of embryos by whole-genome sequencing: now, in the future or never?

Winand R, Hens K, Dondorp W, de Wert G, Moreau Y, Vermeesch JR, Liebaers I, Aerts J.

Hum Reprod. 2014 Apr;29(4):842-51. doi: 10.1093/humrep/deu005. Epub 2014 Feb 2.

PMID:
24491297
[PubMed - indexed for MEDLINE]
7.

The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models.

Yen J, White RM, Wedge DC, Van Loo P, de Ridder J, Capper A, Richardson J, Jones D, Raine K, Watson IR, Wu CJ, Cheng J, Martincorena I, Nik-Zainal S, Mudie L, Moreau Y, Marshall J, Ramakrishna M, Tarpey P, Shlien A, Whitmore I, Gamble S, Latimer C, Langdon E, Kaufman C, Dovey M, Taylor A, Menzies A, McLaren S, O'Meara S, Butler A, Teague J, Lister J, Chin L, Campbell P, Adams DJ, Zon LI, Patton EE, Stemple DL, Futreal PA.

Genome Biol. 2013;14(10):R113.

PMID:
24148783
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

eXtasy: variant prioritization by genomic data fusion.

Sifrim A, Popovic D, Tranchevent LC, Ardeshirdavani A, Sakai R, Konings P, Vermeesch JR, Aerts J, De Moor B, Moreau Y.

Nat Methods. 2013 Nov;10(11):1083-4. doi: 10.1038/nmeth.2656. Epub 2013 Sep 29.

PMID:
24076761
[PubMed - indexed for MEDLINE]
9.

Concordance of gene expression in human protein complexes reveals tissue specificity and pathology.

Börnigen D, Pers TH, Thorrez L, Huttenhower C, Moreau Y, Brunak S.

Nucleic Acids Res. 2013 Oct;41(18):e171. doi: 10.1093/nar/gkt661. Epub 2013 Aug 5.

PMID:
23921638
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Hydrogen bonding to the cysteine ligand of superoxide reductase: acid-base control of the reaction intermediates.

Tremey E, Bonnot F, Moreau Y, Berthomieu C, Desbois A, Favaudon V, Blondin G, Houée-Levin C, Nivière V.

J Biol Inorg Chem. 2013 Oct;18(7):815-30. doi: 10.1007/s00775-013-1025-1. Epub 2013 Aug 6.

PMID:
23917995
[PubMed - indexed for MEDLINE]
11.

Unraveling genomic variation from next generation sequencing data.

Pavlopoulos GA, Oulas A, Iacucci E, Sifrim A, Moreau Y, Schneider R, Aerts J, Iliopoulos I.

BioData Min. 2013 Jul 25;6(1):13. doi: 10.1186/1756-0381-6-13.

PMID:
23885890
[PubMed]
Free PMC Article
12.

Single-cell paired-end genome sequencing reveals structural variation per cell cycle.

Voet T, Kumar P, Van Loo P, Cooke SL, Marshall J, Lin ML, Zamani Esteki M, Van der Aa N, Mateiu L, McBride DJ, Bignell GR, McLaren S, Teague J, Butler A, Raine K, Stebbings LA, Quail MA, D'Hooghe T, Moreau Y, Futreal PA, Stratton MR, Vermeesch JR, Campbell PJ.

Nucleic Acids Res. 2013 Jul;41(12):6119-38. doi: 10.1093/nar/gkt345. Epub 2013 Apr 29.

PMID:
23630320
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Meander: visually exploring the structural variome using space-filling curves.

Pavlopoulos GA, Kumar P, Sifrim A, Sakai R, Lin ML, Voet T, Moreau Y, Aerts J.

Nucleic Acids Res. 2013 Jun;41(11):e118. doi: 10.1093/nar/gkt254. Epub 2013 Apr 19.

PMID:
23605045
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Mutual inhibition among postmitotic neurons regulates robustness of brain wiring in Drosophila.

Langen M, Koch M, Yan J, De Geest N, Erfurth ML, Pfeiffer BD, Schmucker D, Moreau Y, Hassan BA.

Elife. 2013 Mar 5;2:e00337. doi: 10.7554/eLife.00337.

PMID:
23471010
[PubMed - in process]
Free PMC Article
15.

Finding the targets of a drug by integration of gene expression data with a protein interaction network.

Laenen G, Thorrez L, Börnigen D, Moreau Y.

Mol Biosyst. 2013 Jul;9(7):1676-85. doi: 10.1039/c3mb25438k. Epub 2013 Feb 26.

PMID:
23443074
[PubMed - indexed for MEDLINE]
16.

Unsymmetrical binding modes of the HOPNO inhibitor of tyrosinase: from model complexes to the enzyme.

Bochot C, Favre E, Dubois C, Baptiste B, Bubacco L, Carrupt PA, Gellon G, Hardré R, Luneau D, Moreau Y, Nurisso A, Réglier M, Serratrice G, Belle C, Jamet H.

Chemistry. 2013 Mar 11;19(11):3655-64. doi: 10.1002/chem.201202643. Epub 2013 Jan 29.

PMID:
23362183
[PubMed - indexed for MEDLINE]
17.

Genome-wide copy number profiling of single cells in S-phase reveals DNA-replication domains.

Van der Aa N, Cheng J, Mateiu L, Zamani Esteki M, Kumar P, Dimitriadou E, Vanneste E, Moreau Y, Vermeesch JR, Voet T.

Nucleic Acids Res. 2013 Apr 1;41(6):e66. doi: 10.1093/nar/gks1352. Epub 2013 Jan 7.

PMID:
23295674
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Interactogeneous: disease gene prioritization using heterogeneous networks and full topology scores.

Gonçalves JP, Francisco AP, Moreau Y, Madeira SC.

PLoS One. 2012;7(11):e49634. doi: 10.1371/journal.pone.0049634. Epub 2012 Nov 19.

PMID:
23185389
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Microarray analysis reveals abnormal chromosomal complements in over 70% of 14 normally developing human embryos.

Mertzanidou A, Wilton L, Cheng J, Spits C, Vanneste E, Moreau Y, Vermeesch JR, Sermon K.

Hum Reprod. 2013 Jan;28(1):256-64. doi: 10.1093/humrep/des362. Epub 2012 Oct 9.

PMID:
23054067
[PubMed - indexed for MEDLINE]
Free Article
20.

An unbiased evaluation of gene prioritization tools.

Börnigen D, Tranchevent LC, Bonachela-Capdevila F, Devriendt K, De Moor B, De Causmaecker P, Moreau Y.

Bioinformatics. 2012 Dec 1;28(23):3081-8. doi: 10.1093/bioinformatics/bts581. Epub 2012 Oct 9.

PMID:
23047555
[PubMed - indexed for MEDLINE]
Free Article
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