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Results: 1 to 20 of 84

1.

Distinct regions of the large extracellular domain of tetraspanin CD9 are involved in the control of human multinucleated giant cell formation.

Hulme RS, Higginbottom A, Palmer J, Partridge LJ, Monk PN.

PLoS One. 2014 Dec 31;9(12):e116289. doi: 10.1371/journal.pone.0116289. eCollection 2014.

2.

Derivation of ligands for the complement C3a receptor from the C-terminus of C5a.

Halai R, Bellows-Peterson ML, Branchett W, Smadbeck J, Kieslich CA, Croker DE, Cooper MA, Morikis D, Woodruff TM, Floudas CA, Monk PN.

Eur J Pharmacol. 2014 Dec 15;745:176-81. doi: 10.1016/j.ejphar.2014.10.041. Epub 2014 Oct 30.

3.

C5a2 can modulate ERK1/2 signaling in macrophages via heteromer formation with C5a1 and β-arrestin recruitment.

Croker DE, Halai R, Kaeslin G, Wende E, Fehlhaber B, Klos A, Monk PN, Cooper MA.

Immunol Cell Biol. 2014 Aug;92(7):631-9. doi: 10.1038/icb.2014.32. Epub 2014 Apr 29.

PMID:
24777312
4.

The Concise Guide to PHARMACOLOGY 2013/14: overview.

Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, McGrath JC, Catterall WA, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators, Abul-Hasn N, Anderson CM, Anderson CM, Araiksinen MS, Arita M, Arthofer E, Barker EL, Barratt C, Barnes NM, Bathgate R, Beart PM, Belelli D, Bennett AJ, Birdsall NJ, Boison D, Bonner TI, Brailsford L, Bröer S, Brown P, Calo G, Carter WG, Catterall WA, Chan SL, Chao MV, Chiang N, Christopoulos A, Chun JJ, Cidlowski J, Clapham DE, Cockcroft S, Connor MA, Cox HM, Cuthbert A, Dautzenberg FM, Davenport AP, Dawson PA, Dent G, Dijksterhuis JP, Dollery CT, Dolphin AC, Donowitz M, Dubocovich ML, Eiden L, Eidne K, Evans BA, Fabbro D, Fahlke C, Farndale R, Fitzgerald GA, Fong TM, Fowler CJ, Fry JR, Funk CD, Futerman AH, Ganapathy V, Gaisnier B, Gershengorn MA, Goldin A, Goldman ID, Gundlach AL, Hagenbuch B, Hales TG, Hammond JR, Hamon M, Hancox JC, Hauger RL, Hay DL, Hobbs AJ, Hollenberg MD, Holliday ND, Hoyer D, Hynes NA, Inui KI, Ishii S, Jacobson KA, Jarvis GE, Jarvis MF, Jensen R, Jones CE, Jones RL, Kaibuchi K, Kanai Y, Kennedy C, Kerr ID, Khan AA, Klienz MJ, Kukkonen JP, Lapoint JY, Leurs R, Lingueglia E, Lippiat J, Lolait SJ, Lummis SC, Lynch JW, MacEwan D, Maguire JJ, Marshall IL, May JM, McArdle CA, McGrath JC, Michel MC, Millar NS, Miller LJ, Mitolo V, Monk PN, Moore PK, Moorhouse AJ, Mouillac B, Murphy PM, Neubig RR, Neumaier J, Niesler B, Obaidat A, Offermanns S, Ohlstein E, Panaro MA, Parsons S, Pwrtwee RG, Petersen J, Pin JP, Poyner DR, Prigent S, Prossnitz ER, Pyne NJ, Pyne S, Quigley JG, Ramachandran R, Richelson EL, Roberts RE, Roskoski R, Ross RA, Roth M, Rudnick G, Ryan RM, Said SI, Schild L, Sanger GJ, Scholich K, Schousboe A, Schulte G, Schulz S, Serhan CN, Sexton PM, Sibley DR, Siegel JM, Singh G, Sitsapesan R, Smart TG, Smith DM, Soga T, Stahl A, Stewart G, Stoddart LA, Summers RJ, Thorens B, Thwaites DT, Toll L, Traynor JR, Usdin TB, Vandenberg RJ, Villalon C, Vore M, Waldman SA, Ward DT, Willars GB, Wonnacott SJ, Wright E, Ye RD, Yonezawa A, Zimmermann M.

Br J Pharmacol. 2013 Dec;170(8):1449-58. doi: 10.1111/bph.12444.

5.

Wild-type but not mutant SOD1 transgenic astrocytes promote the efficient generation of motor neuron progenitors from mouse embryonic stem cells.

Christou YA, Ohyama K, Placzek M, Monk PN, Shaw PJ.

BMC Neurosci. 2013 Oct 17;14:126. doi: 10.1186/1471-2202-14-126.

6.

Changes and regulation of the C5a receptor on neutrophils during septic shock in humans.

Unnewehr H, Rittirsch D, Sarma JV, Zetoune F, Flierl MA, Perl M, Denk S, Weiss M, Schneider ME, Monk PN, Neff T, Mihlan M, Barth H, Gebhard F, Ward PA, Huber-Lang M.

J Immunol. 2013 Apr 15;190(8):4215-25. doi: 10.4049/jimmunol.1200534. Epub 2013 Mar 11.

7.

International Union of Basic and Clinical Pharmacology. [corrected]. LXXXVII. Complement peptide C5a, C4a, and C3a receptors.

Klos A, Wende E, Wareham KJ, Monk PN.

Pharmacol Rev. 2013 Jan;65(1):500-43. Review. Erratum in: Pharmacol Rev. 2014 Apr;66(2):466.

8.

Heterogeneity in the responses of human lung mast cells to stem cell factor.

Lewis A, Wan J, Baothman B, Monk PN, Suvarna SK, Peachell PT.

Clin Exp Allergy. 2013 Jan;43(1):50-9. doi: 10.1111/cea.12045.

PMID:
23278880
9.

C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay.

Reis ES, Chen H, Sfyroera G, Monk PN, Köhl J, Ricklin D, Lambris JD.

J Immunol. 2012 Nov 15;189(10):4797-805. doi: 10.4049/jimmunol.1200834. Epub 2012 Oct 5.

10.

Generation of complement component C5a by ischemic neurons promotes neuronal apoptosis.

Pavlovski D, Thundyil J, Monk PN, Wetsel RA, Taylor SM, Woodruff TM.

FASEB J. 2012 Sep;26(9):3680-90. doi: 10.1096/fj.11-202382. Epub 2012 May 31.

11.

De novo peptide design with C3a receptor agonist and antagonist activities: theoretical predictions and experimental validation.

Bellows-Peterson ML, Fung HK, Floudas CA, Kieslich CA, Zhang L, Morikis D, Wareham KJ, Monk PN, Hawksworth OA, Woodruff TM.

J Med Chem. 2012 May 10;55(9):4159-68. doi: 10.1021/jm201609k. Epub 2012 Apr 20.

12.

Tetraspanins: gateways for infection.

Monk PN, Partridge LJ.

Infect Disord Drug Targets. 2012 Feb;12(1):4-17. Review.

PMID:
22034932
13.

A comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective function.

Sargsyan SA, Blackburn DJ, Barber SC, Grosskreutz J, De Vos KJ, Monk PN, Shaw PJ.

BMC Neurosci. 2011 Sep 23;12:91. doi: 10.1186/1471-2202-12-91.

14.

Cooperative role for tetraspanins in adhesin-mediated attachment of bacterial species to human epithelial cells.

Green LR, Monk PN, Partridge LJ, Morris P, Gorringe AR, Read RC.

Infect Immun. 2011 Jun;79(6):2241-9. doi: 10.1128/IAI.01354-10. Epub 2011 Apr 4.

15.

The role of tetraspanins in fusion.

Fanaei M, Monk PN, Partridge LJ.

Biochem Soc Trans. 2011 Apr;39(2):524-8. doi: 10.1042/BST0390524. Review.

PMID:
21428932
16.

Contrasting effects of cerebrospinal fluid from motor neuron disease patients on the survival of primary motor neurons cultured with or without glia.

Barber SC, Wood-Allum CA, Sargsyan SA, Walsh T, Cox LE, Monk PN, Shaw PJ.

Amyotroph Lateral Scler. 2011 Jul;12(4):257-63. doi: 10.3109/17482968.2011.560672. Epub 2011 Mar 3.

PMID:
21366496
17.

The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9.

Gutiérrez-López MD, Gilsanz A, Yáñez-Mó M, Ovalle S, Lafuente EM, Domínguez C, Monk PN, González-Alvaro I, Sánchez-Madrid F, Cabañas C.

Cell Mol Life Sci. 2011 Oct;68(19):3275-92. doi: 10.1007/s00018-011-0639-0. Epub 2011 Mar 2.

PMID:
21365281
18.

Strategies for targeting tetraspanin proteins: potential therapeutic applications in microbial infections.

Hassuna N, Monk PN, Moseley GW, Partridge LJ.

BioDrugs. 2009;23(6):341-59. doi: 10.2165/11315650-000000000-00000. Review.

PMID:
19894777
19.

Mutant SOD1 G93A microglia have an inflammatory phenotype and elevated production of MCP-1.

Sargsyan SA, Blackburn DJ, Barber SC, Monk PN, Shaw PJ.

Neuroreport. 2009 Oct 28;20(16):1450-5. doi: 10.1097/WNR.0b013e328331e8fa.

20.

Distinct roles for tetraspanins CD9, CD63 and CD81 in the formation of multinucleated giant cells.

Parthasarathy V, Martin F, Higginbottom A, Murray H, Moseley GW, Read RC, Mal G, Hulme R, Monk PN, Partridge LJ.

Immunology. 2009 Jun;127(2):237-48.

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