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Items: 1 to 20 of 133

1.

PI3-kinase mutation linked to insulin and growth factor resistance in vivo.

Winnay JN, Solheim MH, Dirice E, Sakaguchi M, Noh HL, Kang HJ, Takahashi H, Chudasama KK, Kim JK, Molven A, Kahn CR, Njølstad PR.

J Clin Invest. 2016 Apr 1;126(4):1401-12. doi: 10.1172/JCI84005. Epub 2016 Mar 14.

PMID:
26974159
2.

The Hypoglycemic Phenotype is Islet Cell-Autonomous in Short-chain Hydroxyacyl-CoA Dehydrogenase (SCHAD) Deficient Mice.

Molven A, Hollister-Lock J, Hu J, Martinez R, Njølstad PR, Liew CW, Weir G, Kulkarni RN.

Diabetes. 2016 Mar 7. pii: db151475. [Epub ahead of print]

PMID:
26953163
3.

Lipase gene fusion: a new route to chronic pancreatitis.

Molven A, Njølstad PR, Weiss FU.

Oncotarget. 2015 Oct 13;6(31):30443-4. doi: 10.18632/oncotarget.5454. No abstract available.

4.

Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma.

Law MH, Bishop DT, Lee JE, Brossard M, Martin NG, Moses EK, Song F, Barrett JH, Kumar R, Easton DF, Pharoah PD, Swerdlow AJ, Kypreou KP, Taylor JC, Harland M, Randerson-Moor J, Akslen LA, Andresen PA, Avril MF, Azizi E, Scarrà GB, Brown KM, Dȩbniak T, Duffy DL, Elder DE, Fang S, Friedman E, Galan P, Ghiorzo P, Gillanders EM, Goldstein AM, Gruis NA, Hansson J, Helsing P, Hočevar M, Höiom V, Ingvar C, Kanetsky PA, Chen WV; GenoMEL Consortium; Essen-Heidelberg Investigators; SDH Study Group; Q-MEGA and QTWIN Investigators; AMFS Investigators; ATHENS Melanoma Study Group, Landi MT, Lang J, Lathrop GM, Lubiński J, Mackie RM, Mann GJ, Molven A, Montgomery GW, Novaković S, Olsson H, Puig S, Puig-Butille JA, Qureshi AA, Radford-Smith GL, van der Stoep N, van Doorn R, Whiteman DC, Craig JE, Schadendorf D, Simms LA, Burdon KP, Nyholt DR, Pooley KA, Orr N, Stratigos AJ, Cust AE, Ward SV, Hayward NK, Han J, Schulze HJ, Dunning AM, Bishop JA, Demenais F, Amos CI, MacGregor S, Iles MM.

Nat Genet. 2015 Sep;47(9):987-95. doi: 10.1038/ng.3373. Epub 2015 Aug 3.

5.

The Chromosome 9p21 CVD- and T2D-Associated Regions in a Norwegian Population (The HUNT2 Survey).

Helgeland Ø, Hertel JK, Molven A, Ræder H, Platou CG, Midthjell K, Hveem K, Nygård O, Njølstad PR, Johansson S.

Int J Endocrinol. 2015;2015:164652. doi: 10.1155/2015/164652. Epub 2015 May 18.

6.

IGHV gene usage and mutational status in follicular lymphoma: Correlations with prognosis and patient age.

Berget E, Molven A, Løkeland T, Helgeland L, Vintermyr OK.

Leuk Res. 2015 Jul;39(7):702-8. doi: 10.1016/j.leukres.2015.03.003. Epub 2015 Mar 19.

7.

A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis.

Fjeld K, Weiss FU, Lasher D, Rosendahl J, Chen JM, Johansson BB, Kirsten H, Ruffert C, Masson E, Steine SJ, Bugert P, Cnop M, Grützmann R, Mayerle J, Mössner J, Ringdal M, Schulz HU, Sendler M, Simon P, Sztromwasser P, Torsvik J, Scholz M, Tjora E, Férec C, Witt H, Lerch MM, Njølstad PR, Johansson S, Molven A.

Nat Genet. 2015 May;47(5):518-22. doi: 10.1038/ng.3249. Epub 2015 Mar 16.

PMID:
25774637
8.

Glycogenin-2 is dispensable for liver glycogen synthesis and glucagon-stimulated glucose release.

Irgens HU, Fjeld K, Johansson BB, Ringdal M, Immervoll H, Leh S, Søvik O, Johansson S, Molven A, Njølstad PR.

J Clin Endocrinol Metab. 2015 May;100(5):E767-75. doi: 10.1210/jc.2014-4337. Epub 2015 Mar 9.

PMID:
25751106
9.

Frequencies of KIT and GNAQ mutations in acral melanoma.

Puntervoll HE, Molven A, Akslen LA.

J Cutan Pathol. 2014 Nov;41(11):893-4. doi: 10.1111/cup.12382. Epub 2014 Nov 3. No abstract available.

PMID:
25363280
10.

Prognostic value of bone marrow involvement by clonal immunoglobulin gene rearrangements in follicular lymphoma.

Berget E, Helgeland L, Liseth K, Løkeland T, Molven A, Vintermyr OK.

J Clin Pathol. 2014 Dec;67(12):1072-7. doi: 10.1136/jclinpath-2014-202382. Epub 2014 Sep 18.

11.

The effect on melanoma risk of genes previously associated with telomere length.

Iles MM, Bishop DT, Taylor JC, Hayward NK, Brossard M, Cust AE, Dunning AM, Lee JE, Moses EK, Akslen LA; AMFS Investigators, Andresen PA, Avril MF, Azizi E, Scarrà GB, Brown KM, Dębniak T, Elder DE, Friedman E, Ghiorzo P, Gillanders EM, Goldstein AM, Gruis NA, Hansson J, Harland M, Helsing P, Hočevar M, Höiom V; IBD investigators, Ingvar C, Kanetsky PA, Landi MT, Lang J, Lathrop GM, Lubiński J, Mackie RM, Martin NG, Molven A, Montgomery GW, Novaković S, Olsson H, Puig S, Puig-Butille JA; QMEGA and QTWIN Investigators, Radford-Smith GL, Randerson-Moor J; SDH Study Group, van der Stoep N, van Doorn R, Whiteman DC, MacGregor S, Pooley KA, Ward SV, Mann GJ, Amos CI, Pharoah PD, Demenais F, Law MH, Newton Bishop JA, Barrett JH; GenoMEL Consortium.

J Natl Cancer Inst. 2014 Sep 17;106(10). pii: dju267. doi: 10.1093/jnci/dju267. Print 2014 Oct.

12.

Endocytosis of secreted carboxyl ester lipase in a syndrome of diabetes and pancreatic exocrine dysfunction.

Torsvik J, Johansson BB, Dalva M, Marie M, Fjeld K, Johansson S, Bjørkøy G, Saraste J, Njølstad PR, Molven A.

J Biol Chem. 2014 Oct 17;289(42):29097-111. doi: 10.1074/jbc.M114.574244. Epub 2014 Aug 25.

13.

Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions.

Barrett JH, Taylor JC, Bright C, Harland M, Dunning AM, Akslen LA, Andresen PA, Avril MF, Azizi E, Bianchi Scarrà G, Brossard M, Brown KM, Dębniak T, Elder DE, Friedman E, Ghiorzo P, Gillanders EM, Gruis NA, Hansson J, Helsing P, Hočevar M, Höiom V, Ingvar C, Landi MT, Lang J, Lathrop GM, Lubiński J, Mackie RM, Molven A, Novaković S, Olsson H, Puig S, Puig-Butille JA, van der Stoep N, van Doorn R, van Workum W, Goldstein AM, Kanetsky PA, Pharoah PD, Demenais F, Hayward NK, Newton Bishop JA, Bishop DT, Iles MM; GenoMEL Consortium.

Int J Cancer. 2015 Mar 15;136(6):1351-60. doi: 10.1002/ijc.29099. Epub 2014 Aug 14.

14.

U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells.

Torsvik A, Stieber D, Enger PØ, Golebiewska A, Molven A, Svendsen A, Westermark B, Niclou SP, Olsen TK, Chekenya Enger M, Bjerkvig R.

Cancer Med. 2014 Aug;3(4):812-24. doi: 10.1002/cam4.219. Epub 2014 May 8.

15.

First in-mouse development and application of a surgically relevant xenograft model of ovarian carcinoma.

Helland O, Popa M, Vintermyr OK, Molven A, Gjertsen BT, Bjørge L, McCormack E.

PLoS One. 2014 Mar 4;9(3):e89527. doi: 10.1371/journal.pone.0089527. eCollection 2014.

16.

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes.

Flannick J, Thorleifsson G, Beer NL, Jacobs SB, Grarup N, Burtt NP, Mahajan A, Fuchsberger C, Atzmon G, Benediktsson R, Blangero J, Bowden DW, Brandslund I, Brosnan J, Burslem F, Chambers J, Cho YS, Christensen C, Douglas DA, Duggirala R, Dymek Z, Farjoun Y, Fennell T, Fontanillas P, Forsén T, Gabriel S, Glaser B, Gudbjartsson DF, Hanis C, Hansen T, Hreidarsson AB, Hveem K, Ingelsson E, Isomaa B, Johansson S, Jørgensen T, Jørgensen ME, Kathiresan S, Kong A, Kooner J, Kravic J, Laakso M, Lee JY, Lind L, Lindgren CM, Linneberg A, Masson G, Meitinger T, Mohlke KL, Molven A, Morris AP, Potluri S, Rauramaa R, Ribel-Madsen R, Richard AM, Rolph T, Salomaa V, Segrè AV, Skärstrand H, Steinthorsdottir V, Stringham HM, Sulem P, Tai ES, Teo YY, Teslovich T, Thorsteinsdottir U, Trimmer JK, Tuomi T, Tuomilehto J, Vaziri-Sani F, Voight BF, Wilson JG, Boehnke M, McCarthy MI, Njølstad PR, Pedersen O; Go-T2D Consortium; T2D-GENES Consortium, Groop L, Cox DR, Stefansson K, Altshuler D.

Nat Genet. 2014 Apr;46(4):357-63. doi: 10.1038/ng.2915. Epub 2014 Mar 2.

17.

Frequency of somatic BRAF mutations in melanocytic lesions from patients in a CDK4 melanoma family.

Puntervoll HE, Molven A, Akslen LA.

Pigment Cell Melanoma Res. 2014 Jan;27(1):149-51. doi: 10.1111/pcmr.12191. Epub 2013 Nov 21. No abstract available.

PMID:
24256466
18.

Generation of prostate tumor-initiating cells is associated with elevation of reactive oxygen species and IL-6/STAT3 signaling.

Qu Y, Oyan AM, Liu R, Hua Y, Zhang J, Hovland R, Popa M, Liu X, Brokstad KA, Simon R, Molven A, Lin B, Zhang WD, McCormack E, Kalland KH, Ke XS.

Cancer Res. 2013 Dec 1;73(23):7090-100. doi: 10.1158/0008-5472.CAN-13-1560. Epub 2013 Oct 7.

19.

Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes.

Flannick J, Beer NL, Bick AG, Agarwala V, Molnes J, Gupta N, Burtt NP, Florez JC, Meigs JB, Taylor H, Lyssenko V, Irgens H, Fox E, Burslem F, Johansson S, Brosnan MJ, Trimmer JK, Newton-Cheh C, Tuomi T, Molven A, Wilson JG, O'Donnell CJ, Kathiresan S, Hirschhorn JN, Njølstad PR, Rolph T, Seidman JG, Gabriel S, Cox DR, Seidman CE, Groop L, Altshuler D.

Nat Genet. 2013 Nov;45(11):1380-5. doi: 10.1038/ng.2794. Epub 2013 Oct 6.

20.

Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancreatic cysts and upregulated MAPK signaling in secretin-stimulated duodenal fluid.

Ræder H, McAllister FE, Tjora E, Bhatt S, Haldorsen I, Hu J, Willems SM, Vesterhus M, El Ouaamari A, Liu M, Ræder MB, Immervoll H, Hoem D, Dimcevski G, Njølstad PR, Molven A, Gygi SP, Kulkarni RN.

Diabetes. 2014 Jan;63(1):259-69. doi: 10.2337/db13-1012. Epub 2013 Sep 23.

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