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Items: 1 to 20 of 407

1.

Histological chorioamnionitis shapes the neonatal transcriptomic immune response.

Weitkamp JH, Guthrie SO, Wong HR, Moldawer LL, Baker HV, Wynn JL.

Early Hum Dev. 2016 Jul;98:1-6. doi: 10.1016/j.earlhumdev.2016.06.001. Epub 2016 Jun 16.

PMID:
27318328
2.

Gender based differences in the genomic response, innate immunity, organ dysfunction and clinical outcomes after severe blunt traumatic injury and hemorrhagic shock.

Lopez MC, Efron PA, Ozrazgat-Baslanti T, Zhang J, Cuschieri J, Maier RV, Minei JP, Baker HV, Moore FA, Moldawer LL, Brakenridge SC.

J Trauma Acute Care Surg. 2016 Jun 14. [Epub ahead of print]

PMID:
27306446
3.

β-Blockade Use for Traumatic Injuries and Immunomodulation: A Review of Proposed Mechanisms and Clinical Evidence.

Loftus TJ, Efron PA, Moldawer LL, Mohr AM.

Shock. 2016 May 11. [Epub ahead of print]

PMID:
27172161
4.

Human Myeloid-derived Suppressor Cells are Associated With Chronic Immune Suppression After Severe Sepsis/Septic Shock.

Mathias B, Delmas AL, Ozrazgat-Baslanti T, Vanzant EL, Szpila BE, Mohr AM, Moore FA, Brakenridge SC, Brumback BA, Moldawer LL, Efron PA; and the Sepsis, Critical Illness Research Center Investigators.

Ann Surg. 2016 May 9. [Epub ahead of print]

PMID:
27163951
5.

Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18.

Wynn JL, Wilson CS, Hawiger J, Scumpia PO, Marshall AF, Liu JH, Zharkikh I, Wong HR, Lahni P, Benjamin JT, Plosa EJ, Weitkamp JH, Sherwood ER, Moldawer LL, Ungaro R, Baker HV, Lopez MC, McElroy SJ, Colliou N, Mohamadzadeh M, Moore DJ.

Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2627-35. doi: 10.1073/pnas.1515793113. Epub 2016 Apr 25.

PMID:
27114524
6.

A Review of GM-CSF Therapy in Sepsis.

Mathias B, Szpila BE, Moore FA, Efron PA, Moldawer LL.

Medicine (Baltimore). 2015 Dec;94(50):e2044. doi: 10.1097/MD.0000000000002044. Review.

7.

What's New in Shock, January 2016?

Moldawer LL.

Shock. 2016 Jan;45(1):1-3. doi: 10.1097/SHK.0000000000000527. No abstract available.

PMID:
26674448
8.

Integrating "big data" into surgical practice.

Mathias B, Lipori G, Moldawer LL, Efron PA.

Surgery. 2016 Feb;159(2):371-4. doi: 10.1016/j.surg.2015.08.043. Epub 2015 Oct 23. Review.

PMID:
26603852
9.

Patterns of gene expression among murine models of hemorrhagic shock/trauma and sepsis.

Mira JC, Szpila BE, Nacionales DC, Lopez MC, Gentile LF, Mathias BJ, Vanzant EL, Ungaro R, Holden D, Rosenthal MD, Rincon J, Verdugo PT, Larson SD, Moore FA, Brakenridge SC, Mohr AM, Baker HV, Moldawer LL, Efron PA.

Physiol Genomics. 2016 Feb;48(2):135-44. doi: 10.1152/physiolgenomics.00072.2015. Epub 2015 Nov 17.

PMID:
26578697
10.

The inflammatory milieu within the pancreatic cancer microenvironment correlates with clinicopathologic parameters, chemoresistance and survival.

Delitto D, Black BS, Sorenson HL, Knowlton AE, Thomas RM, Sarosi GA, Moldawer LL, Behrns KE, Liu C, George TJ, Trevino JG, Wallet SM, Hughes SJ.

BMC Cancer. 2015 Oct 24;15:783. doi: 10.1186/s12885-015-1820-x.

11.

Downstream mediators of the intratumoral interferon response suppress antitumor immunity, induce gemcitabine resistance and associate with poor survival in human pancreatic cancer.

Delitto D, Perez C, Han S, Gonzalo DH, Pham K, Knowlton AE, Graves CL, Behrns KE, Moldawer LL, Thomas RM, Liu C, George TJ Jr, Trevino JG, Wallet SM, Hughes SJ.

Cancer Immunol Immunother. 2015 Dec;64(12):1553-63. doi: 10.1007/s00262-015-1760-y. Epub 2015 Sep 30.

PMID:
26423423
12.

A Detailed Characterization of the Dysfunctional Immunity and Abnormal Myelopoiesis Induced by Severe Shock and Trauma in the Aged.

Nacionales DC, Szpila B, Ungaro R, Lopez MC, Zhang J, Gentile LF, Cuenca AL, Vanzant E, Mathias B, Jyot J, Westerveld D, Bihorac A, Joseph A, Mohr A, Duckworth LV, Moore FA, Baker HV, Leeuwenburgh C, Moldawer LL, Brakenridge S, Efron PA.

J Immunol. 2015 Sep 1;195(5):2396-407. doi: 10.4049/jimmunol.1500984. Epub 2015 Aug 5.

PMID:
26246141
13.

Postnatal Age Is a Critical Determinant of the Neonatal Host Response to Sepsis.

Wynn JL, Guthrie SO, Wong HR, Lahni P, Ungaro R, Lopez MC, Baker HV, Moldawer LL.

Mol Med. 2015 Jun 2;21:496-504. doi: 10.2119/molmed.2015.00064.

14.

The future of murine sepsis and trauma research models.

Efron PA, Mohr AM, Moore FA, Moldawer LL.

J Leukoc Biol. 2015 Dec;98(6):945-52. doi: 10.1189/jlb.5MR0315-127R. Epub 2015 Jun 1. Review.

PMID:
26034205
15.

Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock.

Vanzant EL, Hilton RE, Lopez CM, Zhang J, Ungaro RF, Gentile LF, Szpila BE, Maier RV, Cuschieri J, Bihorac A, Leeuwenburgh C, Moore FA, Baker HV, Moldawer LL, Brakenridge SC, Efron PA; Inflammation and Host Response to Injury Investigators.

Crit Care. 2015 Mar 4;19:77. doi: 10.1186/s13054-015-0788-x.

16.

Improved emergency myelopoiesis and survival in neonatal sepsis by caspase-1/11 ablation.

Gentile LF, Cuenca AL, Cuenca AG, Nacionales DC, Ungaro R, Efron PA, Moldawer LL, Larson SD.

Immunology. 2015 Jun;145(2):300-11. doi: 10.1111/imm.12450.

17.

TRIF-dependent innate immune activation is critical for survival to neonatal gram-negative sepsis.

Cuenca AG, Joiner DN, Gentile LF, Cuenca AL, Wynn JL, Kelly-Scumpia KM, Scumpia PO, Behrns KE, Efron PA, Nacionales D, Lui C, Wallet SM, Reeves WH, Mathews CE, Moldawer LL.

J Immunol. 2015 Feb 1;194(3):1169-77. doi: 10.4049/jimmunol.1302676. Epub 2014 Dec 29.

18.

Mice are not men.

Warren HS, Tompkins RG, Moldawer LL, Seok J, Xu W, Mindrinos MN, Maier RV, Xiao W, Davis RW.

Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):E345. doi: 10.1073/pnas.1414857111. Epub 2014 Dec 24. No abstract available.

19.

What's new in Shock, October 2014?

Moldawer LL.

Shock. 2014 Oct;42(4):283-5. doi: 10.1097/SHK.0000000000000246. No abstract available.

PMID:
25225834
20.

Delayed emergency myelopoiesis following polymicrobial sepsis in neonates.

Cuenca AG, Cuenca AL, Gentile LF, Efron PA, Islam S, Moldawer LL, Kays DW, Larson SD.

Innate Immun. 2015 May;21(4):386-91. doi: 10.1177/1753425914542445. Epub 2014 Aug 7.

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