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Results: 5

1.

BCKDH: the missing link in apicomplexan mitochondrial metabolism is required for full virulence of Toxoplasma gondii and Plasmodium berghei.

Oppenheim RD, Creek DJ, Macrae JI, Modrzynska KK, Pino P, Limenitakis J, Polonais V, Seeber F, Barrett MP, Billker O, McConville MJ, Soldati-Favre D.

PLoS Pathog. 2014 Jul 17;10(7):e1004263. doi: 10.1371/journal.ppat.1004263. eCollection 2014 Jul.

PMID:
25032958
[PubMed - in process]
Free PMC Article
2.

A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium.

Sinha A, Hughes KR, Modrzynska KK, Otto TD, Pfander C, Dickens NJ, Religa AA, Bushell E, Graham AL, Cameron R, Kafsack BF, Williams AE, Llinás M, Berriman M, Billker O, Waters AP.

Nature. 2014 Mar 13;507(7491):253-7. doi: 10.1038/nature12970. Epub 2014 Feb 23.

PMID:
24572359
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Artemisinin resistance in rodent malaria--mutation in the AP2 adaptor μ-chain suggests involvement of endocytosis and membrane protein trafficking.

Henriques G, Martinelli A, Rodrigues L, Modrzynska K, Fawcett R, Houston DR, Borges ST, d'Alessandro U, Tinto H, Karema C, Hunt P, Cravo P.

Malar J. 2013 Apr 5;12:118. doi: 10.1186/1475-2875-12-118.

PMID:
23561245
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Genomewide scan reveals amplification of mdr1 as a common denominator of resistance to mefloquine, lumefantrine, and artemisinin in Plasmodium chabaudi malaria parasites.

Borges S, Cravo P, Creasey A, Fawcett R, Modrzynska K, Rodrigues L, Martinelli A, Hunt P.

Antimicrob Agents Chemother. 2011 Oct;55(10):4858-65. doi: 10.1128/AAC.01748-10. Epub 2011 Jun 27.

PMID:
21709099
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites.

Hunt P, Martinelli A, Modrzynska K, Borges S, Creasey A, Rodrigues L, Beraldi D, Loewe L, Fawcett R, Kumar S, Thomson M, Trivedi U, Otto TD, Pain A, Blaxter M, Cravo P.

BMC Genomics. 2010 Sep 16;11:499. doi: 10.1186/1471-2164-11-499.

PMID:
20846421
[PubMed - indexed for MEDLINE]
Free PMC Article

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