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Items: 1 to 20 of 27


A top-down view of the tumor microenvironment: structure, cells and signaling.

Bhome R, Bullock MD, Al Saihati HA, Goh RW, Primrose JN, Sayan AE, Mirnezami AH.

Front Cell Dev Biol. 2015 May 29;3:33. doi: 10.3389/fcell.2015.00033. eCollection 2015. Review.


miR-19-Mediated Inhibition of Transglutaminase-2 Leads to Enhanced Invasion and Metastasis in Colorectal Cancer.

Cellura D, Pickard K, Quaratino S, Parker H, Strefford JC, Thomas GJ, Mitter R, Mirnezami AH, Peake NJ.

Mol Cancer Res. 2015 Jul;13(7):1095-105. doi: 10.1158/1541-7786.MCR-14-0466. Epub 2015 May 1.


The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis.

Ling H, Pickard K, Ivan C, Isella C, Ikuo M, Mitter R, Spizzo R, Bullock MD, Braicu C, Pileczki V, Vincent K, Pichler M, Stiegelbauer V, Hoefler G, Almeida MI, Hsiao A, Zhang X, Primrose JN, Packham GK, Liu K, Bojja K, GafĂ  R, Xiao L, Rossi S, Song JH, Vannini I, Fanini F, Kopetz S, Zweidler-McKay P, Wang X, Ionescu C, Irimie A, Fabbri M, Lanza G, Hamilton SR, Berindan-Neagoe I, Medico E, Mirnezami AH, Calin GA, Nicoloso MS.

Gut. 2015 Mar 24. pii: gutjnl-2015-309372. doi: 10.1136/gutjnl-2015-309372. [Epub ahead of print]


Stratifying risk of recurrence in stage II colorectal cancer using deregulated stromal and epithelial microRNAs.

Bullock MD, Pickard K, Mitter R, Sayan AE, Primrose JN, Ivan C, Calin GA, Thomas GJ, Packham GK, Mirnezami AH.

Oncotarget. 2015 Mar 30;6(9):7262-79.


Systematic review of emergent laparoscopic colorectal surgery for benign and malignant disease.

Chand M, Siddiqui MR, Gupta A, Rasheed S, Tekkis P, Parvaiz A, Mirnezami AH, Qureshi T.

World J Gastroenterol. 2014 Dec 7;20(45):16956-63. doi: 10.3748/wjg.v20.i45.16956.


Cytoreductive surgery and intraperitoneal chemotherapy for colorectal peritoneal metastases.

Mirnezami R, Moran BJ, Harvey K, Cecil T, Chandrakumaran K, Carr N, Mohamed F, Mirnezami AH.

World J Gastroenterol. 2014 Oct 14;20(38):14018-32. doi: 10.3748/wjg.v20.i38.14018. Review.


Cytoreductive surgery in combination with hyperthermic intraperitoneal chemotherapy improves survival in patients with colorectal peritoneal metastases compared with systemic chemotherapy alone.

Mirnezami R, Mehta AM, Chandrakumaran K, Cecil T, Moran BJ, Carr N, Verwaal VJ, Mohamed F, Mirnezami AH.

Br J Cancer. 2014 Oct 14;111(8):1500-8. doi: 10.1038/bjc.2014.419. Epub 2014 Sep 16.


Molecular profiling of the invasive tumor microenvironment in a 3-dimensional model of colorectal cancer cells and ex vivo fibroblasts.

Bullock MD, Mellone M, Pickard KM, Sayan AE, Mitter R, Primrose JN, Packham GK, Thomas G, Mirnezami AH.

J Vis Exp. 2014 Apr 29;(86). doi: 10.3791/51475.


miR-153 supports colorectal cancer progression via pleiotropic effects that enhance invasion and chemotherapeutic resistance.

Zhang L, Pickard K, Jenei V, Bullock MD, Bruce A, Mitter R, Kelly G, Paraskeva C, Strefford J, Primrose J, Thomas GJ, Packham G, Mirnezami AH.

Cancer Res. 2013 Nov 1;73(21):6435-47. doi: 10.1158/0008-5472.CAN-12-3308. Epub 2013 Aug 15.


FOXO3 expression during colorectal cancer progression: biomarker potential reflects a tumour suppressor role.

Bullock MD, Bruce A, Sreekumar R, Curtis N, Cheung T, Reading I, Primrose JN, Ottensmeier C, Packham GK, Thomas G, Mirnezami AH.

Br J Cancer. 2013 Jul 23;109(2):387-94. doi: 10.1038/bjc.2013.355. Epub 2013 Jul 4.


Pleiotropic actions of miR-21 highlight the critical role of deregulated stromal microRNAs during colorectal cancer progression.

Bullock MD, Pickard KM, Nielsen BS, Sayan AE, Jenei V, Mellone M, Mitter R, Primrose JN, Thomas GJ, Packham GK, Mirnezami AH.

Cell Death Dis. 2013 Jun 20;4:e684. doi: 10.1038/cddis.2013.213. Erratum in: Cell Death Dis. 2013;4:e748. Mirenzami, AH [corrected to Mirnezami, AH].


Intraoperative radiotherapy in colorectal cancer: systematic review and meta-analysis of techniques, long-term outcomes, and complications.

Mirnezami R, Chang GJ, Das P, Chandrakumaran K, Tekkis P, Darzi A, Mirnezami AH.

Surg Oncol. 2013 Mar;22(1):22-35. doi: 10.1016/j.suronc.2012.11.001. Epub 2012 Dec 25. Review.


A prospective case-control study of extralevator abdominoperineal excision (ELAPE) of the rectum versus conventional laparoscopic and open abdominoperineal excision: comparative analysis of short-term outcomes and quality of life.

Vaughan-Shaw PG, Cheung T, Knight JS, Nichols PH, Pilkington SA, Mirnezami AH.

Tech Coloproctol. 2012 Oct;16(5):355-62. doi: 10.1007/s10151-012-0851-4. Epub 2012 Jul 10.


The adaptive immune response to colorectal cancer: from the laboratory to clinical practice.

Curtis NJ, Primrose JN, Thomas GJ, Mirnezami AH, Ottensmeier CH.

Eur J Surg Oncol. 2012 Oct;38(10):889-96. doi: 10.1016/j.ejso.2012.05.011. Epub 2012 Jun 19. Review.


MicroRNA Control of Invasion and Metastasis Pathways.

Sreekumar R, Sayan BS, Mirnezami AH, Sayan AE.

Front Genet. 2011 Sep 5;2:58. doi: 10.3389/fgene.2011.00058. eCollection 2011.


MicroRNAs: critical regulators of epithelial to mesenchymal (EMT) and mesenchymal to epithelial transition (MET) in cancer progression.

Bullock MD, Sayan AE, Packham GK, Mirnezami AH.

Biol Cell. 2012 Jan;104(1):3-12. doi: 10.1111/boc.201100115. Epub 2011 Dec 9. Review.


Acute radiation enteritis causing small bowel obstruction.

Curtis NJ, Bryant T, Raj S, Bateman AR, Mirnezami AH.

Ann R Coll Surg Engl. 2011 Oct;93(7):e129-30. doi: 10.1308/10.1308/147870811X602122.


Early experience with laparoscopic extralevator abdominoperineal excision within an enhanced recovery setting: analysis of short-term outcomes and quality of life.

Vaughan-Shaw PG, King AT, Cheung T, Beck NE, Knight JS, Nichols PH, Nugent KP, Pilkington SA, Smallwood JA, Mirnezami AH.

Ann R Coll Surg Engl. 2011 Sep;93(6):451-9. doi: 10.1308/003588411X588621.


Short- and long-term outcomes after laparoscopic and open hepatic resection: systematic review and meta-analysis.

Mirnezami R, Mirnezami AH, Chandrakumaran K, Abu Hilal M, Pearce NW, Primrose JN, Sutcliffe RP.

HPB (Oxford). 2011 May;13(5):295-308. doi: 10.1111/j.1477-2574.2011.00295.x. Epub 2011 Mar 2. Review.


Clinical algorithms for the surgical management of locally recurrent rectal cancer.

Mirnezami AH, Sagar PM, Kavanagh D, Witherspoon P, Lee P, Winter D.

Dis Colon Rectum. 2010 Sep;53(9):1248-57. doi: 10.1007/DCR.0b013e3181e10b0e. Review.

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