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Items: 1 to 20 of 48


Construction of stable packaging cell lines for clinical lentiviral vector production.

Sanber KS, Knight SB, Stephen SL, Bailey R, Escors D, Minshull J, Santilli G, Thrasher AJ, Collins MK, Takeuchi Y.

Sci Rep. 2015 Mar 12;5:9021. doi: 10.1038/srep09021.


Mapping of amino acid substitutions conferring herbicide resistance in wheat glutathione transferase.

Govindarajan S, Mannervik B, Silverman JA, Wright K, Regitsky D, Hegazy U, Purcell TJ, Welch M, Minshull J, Gustafsson C.

ACS Synth Biol. 2015 Mar 20;4(3):221-7. doi: 10.1021/sb500242x. Epub 2014 Jun 13.


Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin.

Midelfort KS, Kumar R, Han S, Karmilowicz MJ, McConnell K, Gehlhaar DK, Mistry A, Chang JS, Anderson M, Villalobos A, Minshull J, Govindarajan S, Wong JW.

Protein Eng Des Sel. 2013 Jan;26(1):25-33. doi: 10.1093/protein/gzs065. Epub 2012 Sep 25.


Engineering genes for predictable protein expression.

Gustafsson C, Minshull J, Govindarajan S, Ness J, Villalobos A, Welch M.

Protein Expr Purif. 2012 May;83(1):37-46. doi: 10.1016/j.pep.2012.02.013. Epub 2012 Mar 8. Review.


In silico design of functional DNA constructs.

Villalobos A, Welch M, Minshull J.

Methods Mol Biol. 2012;852:197-213. doi: 10.1007/978-1-61779-564-0_15.


Analysis of the ketosynthase-chain length factor heterodimer from the fredericamycin polyketide synthase.

Szu PH, Govindarajan S, Meehan MJ, Das A, Nguyen DD, Dorrestein PC, Minshull J, Khosla C.

Chem Biol. 2011 Aug 26;18(8):1021-31. doi: 10.1016/j.chembiol.2011.07.015.


Designing genes for successful protein expression.

Welch M, Villalobos A, Gustafsson C, Minshull J.

Methods Enzymol. 2011;498:43-66. doi: 10.1016/B978-0-12-385120-8.00003-6.


Biosynthesis of monomers for plastics from renewable oils.

Lu W, Ness JE, Xie W, Zhang X, Minshull J, Gross RA.

J Am Chem Soc. 2010 Nov 3;132(43):15451-5. doi: 10.1021/ja107707v.


Design parameters to control synthetic gene expression in Escherichia coli.

Welch M, Govindarajan S, Ness JE, Villalobos A, Gurney A, Minshull J, Gustafsson C.

PLoS One. 2009 Sep 14;4(9):e7002. doi: 10.1371/journal.pone.0007002.


Engineering the Salmonella type III secretion system to export spider silk monomers.

Widmaier DM, Tullman-Ercek D, Mirsky EA, Hill R, Govindarajan S, Minshull J, Voigt CA.

Mol Syst Biol. 2009;5:309. doi: 10.1038/msb.2009.62. Epub 2009 Sep 15.


Preventing the misuse of gene synthesis.

Minshull J, Wagner R.

Nat Biotechnol. 2009 Sep;27(9):800-1; author reply 801. doi: 10.1038/nbt0909-800. No abstract available.


SCHEMA recombination of a fungal cellulase uncovers a single mutation that contributes markedly to stability.

Heinzelman P, Snow CD, Smith MA, Yu X, Kannan A, Boulware K, Villalobos A, Govindarajan S, Minshull J, Arnold FH.

J Biol Chem. 2009 Sep 25;284(39):26229-33. doi: 10.1074/jbc.C109.034058. Epub 2009 Jul 22.


You're one in a googol: optimizing genes for protein expression.

Welch M, Villalobos A, Gustafsson C, Minshull J.

J R Soc Interface. 2009 Aug 6;6 Suppl 4:S467-76. doi: 10.1098/rsif.2008.0520.focus. Epub 2009 Mar 11. Review.


A family of thermostable fungal cellulases created by structure-guided recombination.

Heinzelman P, Snow CD, Wu I, Nguyen C, Villalobos A, Govindarajan S, Minshull J, Arnold FH.

Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5610-5. doi: 10.1073/pnas.0901417106. Epub 2009 Mar 23.


The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction.

Nilsson J, Yekezare M, Minshull J, Pines J.

Nat Cell Biol. 2008 Dec;10(12):1411-20. doi: 10.1038/ncb1799. Epub 2008 Nov 9.


Protein engineering of improved prolyl endopeptidases for celiac sprue therapy.

Ehren J, Govindarajan S, MorĂ³n B, Minshull J, Khosla C.

Protein Eng Des Sel. 2008 Dec;21(12):699-707. doi: 10.1093/protein/gzn050. Epub 2008 Oct 4.


Engineering proteinase K using machine learning and synthetic genes.

Liao J, Warmuth MK, Govindarajan S, Ness JE, Wang RP, Gustafsson C, Minshull J.

BMC Biotechnol. 2007 Mar 26;7:16.


Gene Designer: a synthetic biology tool for constructing artificial DNA segments.

Villalobos A, Ness JE, Gustafsson C, Minshull J, Govindarajan S.

BMC Bioinformatics. 2006 Jun 6;7:285.


Predicting enzyme function from protein sequence.

Minshull J, Ness JE, Gustafsson C, Govindarajan S.

Curr Opin Chem Biol. 2005 Apr;9(2):202-9. Review.


Codon bias and heterologous protein expression.

Gustafsson C, Govindarajan S, Minshull J.

Trends Biotechnol. 2004 Jul;22(7):346-53. Review.

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