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Results: 1 to 20 of 590

1.

The RAC1 P29S Hotspot Mutation in Melanoma Confers Resistance to Pharmacological Inhibition of RAF.

Watson IR, Li L, Cabeceiras PK, Mahdavi M, Gutschner T, Genovese G, Wang G, Fang Z, Tepper JM, Stemke-Hale K, Tsai KY, Davies MA, Mills GB, Chin L.

Cancer Res. 2014 Jul 23. pii: canres.1232.2014. [Epub ahead of print]

PMID:
25056119
[PubMed - as supplied by publisher]
2.

Promising Rationally Derived Combination Therapy with PI3K and CDK4/6 Inhibitors.

Muranen T, Meric-Bernstam F, Mills GB.

Cancer Cell. 2014 Jul 14;26(1):7-9. doi: 10.1016/j.ccr.2014.06.020.

PMID:
25026206
[PubMed - in process]
3.

Peroxiredoxin-1 protects estrogen receptor alpha from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer.

O Leary PC, Terrile M, Bajor M, Gaj P, Hennessy BT, Mills GB, Zagozdzon A, O Connor DP, Brennan DJ, Connor K, Li J, Gonzalez-Angulo AM, Sun HD, Pu JX, Pontén F, Uhlén M, Jirström K, Nowis DA, Crown JP, Zagozdzon R, Gallagher WM.

Breast Cancer Res. 2014 Jul 10;16(4):R79. [Epub ahead of print]

PMID:
25011585
[PubMed - as supplied by publisher]
4.

Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis.

Liu XD, Yao J, Tripathi DN, Ding Z, Xu Y, Sun M, Zhang J, Bai S, German P, Hoang A, Zhou L, Jonasch D, Zhang X, Conti CJ, Efstathiou E, Tannir NM, Eissa NT, Mills GB, Walker CL, Jonasch E.

Oncogene. 2014 Jul 7. doi: 10.1038/onc.2014.199. [Epub ahead of print]

PMID:
24998849
[PubMed - as supplied by publisher]
5.

AKT Pathway Genes Define 5 Prognostic Subgroups in Glioblastoma.

Joy A, Ramesh A, Smirnov I, Reiser M, Misra A, Shapiro WR, Mills GB, Kim S, Feuerstein BG.

PLoS One. 2014 Jul 1;9(7):e100827. doi: 10.1371/journal.pone.0100827. eCollection 2014.

PMID:
24984002
[PubMed - in process]
Free PMC Article
6.

Targeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancer.

Liu S, Meng X, Chen H, Liu W, Liu W, Miller T, Murph M, Lu Y, Zhang F, Iurascu MG, Arteaga CL, Mills GB, Meric-Bernstam F, González-Angulo AM.

Oncotarget. 2014 May 27. [Epub ahead of print]

PMID:
24979294
[PubMed - as supplied by publisher]
Free Article
7.

Definition of PKC-α, CDK6 and MET as therapeutic targets in triple-negative breast cancer.

Hsu YH, Yao J, Chan LC, Wu TJ, Hsu JL, Fang YF, Wei Y, Wu Y, Huang WC, Liu CL, Chang YC, Wang MY, Li CW, Shen J, Chen MK, Sahin AA, Sood A, Mills GB, Yu D, Hortobagyi GN, Hung MC.

Cancer Res. 2014 Jun 26. pii: canres.0584.2014. [Epub ahead of print]

PMID:
24970481
[PubMed - as supplied by publisher]
8.

Assessing the clinical utility of cancer genomic and proteomic data across tumor types.

Yuan Y, Van Allen EM, Omberg L, Wagle N, Amin-Mansour A, Sokolov A, Byers LA, Xu Y, Hess KR, Diao L, Han L, Huang X, Lawrence MS, Weinstein JN, Stuart JM, Mills GB, Garraway LA, Margolin AA, Getz G, Liang H.

Nat Biotechnol. 2014 Jul;32(7):644-52. doi: 10.1038/nbt.2940. Epub 2014 Jun 22.

PMID:
24952901
[PubMed - in process]
9.

A curated census of autophagy-modulating proteins and small molecules: Candidate targets for cancer therapy.

Lorenzi PL, Claerhout S, Mills GB, Weinstein JN.

Autophagy. 2014 Jul 1;10(7):1316-26. doi: 10.4161/auto.28773. Epub 2014 May 12.

PMID:
24906121
[PubMed - in process]
Free Article
10.

Influence of biospecimen variables on proteomic biomarkers in breast cancer.

Meric-Bernstam F, Akcakanat A, Chen H, Sahin A, Tarco E, Carkaci S, Adrada BE, Singh G, Do KA, Garces ZM, Mittendorf E, Babiera G, Bedrosian I, Hwang R, Krishnamurthy S, Symmans WF, Gonzalez-Angulo AM, Mills GB.

Clin Cancer Res. 2014 Jul 15;20(14):3870-83. doi: 10.1158/1078-0432.CCR-13-1507. Epub 2014 Jun 3.

PMID:
24895461
[PubMed - in process]
11.

A pan-cancer proteomic perspective on The Cancer Genome Atlas.

Akbani R, Ng PK, Werner HM, Shahmoradgoli M, Zhang F, Ju Z, Liu W, Yang JY, Yoshihara K, Li J, Ling S, Seviour EG, Ram PT, Minna JD, Diao L, Tong P, Heymach JV, Hill SM, Dondelinger F, Städler N, Byers LA, Meric-Bernstam F, Weinstein JN, Broom BM, Verhaak RG, Liang H, Mukherjee S, Lu Y, Mills GB.

Nat Commun. 2014 May 29;5:3887. doi: 10.1038/ncomms4887.

PMID:
24871328
[PubMed - in process]
12.

Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation.

Zhou G, Wang J, Zhao M, Xie TX, Tanaka N, Sano D, Patel AA, Ward AM, Sandulache VC, Jasser SA, Skinner HD, Fitzgerald AL, Osman AA, Wei Y, Xia X, Songyang Z, Mills GB, Hung MC, Caulin C, Liang J, Myers JN.

Mol Cell. 2014 Jun 19;54(6):960-74. doi: 10.1016/j.molcel.2014.04.024. Epub 2014 May 22.

PMID:
24857548
[PubMed - in process]
13.

Unraveling the regulatory connections between two controllers of breast cancer cell fate.

Lee J, Tiwari A, Shum V, Mills GB, Mancini MA, Igoshin OA, Balázsi G.

Nucleic Acids Res. 2014;42(11):6839-49. doi: 10.1093/nar/gku360. Epub 2014 May 3.

PMID:
24792166
[PubMed - in process]
Free PMC Article
14.

Realizing the Promise of Reverse Phase Protein Arrays for Clinical, Translational, and Basic Research: A Workshop Report: The RPPA (Reverse Phase Protein Array) Society.

Akbani R, Becker KF, Carragher N, Goldstein T, de Koning L, Korf U, Liotta L, Mills GB, Nishizuka SS, Pawlak M, Petricoin EF 3rd, Pollard HB, Serrels B, Zhu J.

Mol Cell Proteomics. 2014 Jul;13(7):1625-43. doi: 10.1074/mcp.O113.034918. Epub 2014 Apr 28.

PMID:
24777629
[PubMed - in process]
15.

Mesenchymal gene program-expressing ovarian cancer spheroids exhibit enhanced mesothelial clearance.

Davidowitz RA, Selfors LM, Iwanicki MP, Elias KM, Karst A, Piao H, Ince TA, Drage MG, Dering J, Konecny GE, Matulonis U, Mills GB, Slamon DJ, Drapkin R, Brugge JS.

J Clin Invest. 2014 Jun 2;124(6):2611-25. doi: 10.1172/JCI69815. Epub 2014 Apr 24.

PMID:
24762435
[PubMed - in process]
Free PMC Article
16.

Genetic and pharmacological strategies to refunctionalize the von Hippel Lindau R167Q mutant protein.

Ding Z, German P, Bai S, Reddy AS, Liu XD, Sun M, Zhou L, Chen X, Zhao X, Wu C, Zhang S, Mills GB, Jonasch E.

Cancer Res. 2014 Jun 1;74(11):3127-36. doi: 10.1158/0008-5472.CAN-13-3213. Epub 2014 Apr 22.

PMID:
24755468
[PubMed - in process]
17.

Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels.

Mertins P, Yang F, Liu T, Mani DR, Petyuk VA, Gillette MA, Clauser KR, Qiao JW, Gritsenko MA, Moore RJ, Levine DA, Townsend R, Erdmann-Gilmore P, Snider JE, Davies SR, Ruggles KV, Fenyo D, Kitchens RT, Li S, Olvera N, Dao F, Rodriguez H, Chan DW, Liebler D, White F, Rodland KD, Mills GB, Smith RD, Paulovich AG, Ellis M, Carr SA.

Mol Cell Proteomics. 2014 Jul;13(7):1690-704. doi: 10.1074/mcp.M113.036392. Epub 2014 Apr 9.

PMID:
24719451
[PubMed - in process]
18.

Open-label randomized clinical trial of standard neoadjuvant chemotherapy with paclitaxel followed by FEC versus the combination of paclitaxel and everolimus followed by FEC in women with triple receptor-negative breast cancer†.

Gonzalez-Angulo AM, Akcakanat A, Liu S, Green MC, Murray JL, Chen H, Palla SL, Koenig KB, Brewster AM, Valero V, Ibrahim NK, Moulder-Thompson S, Litton JK, Tarco E, Moore J, Flores P, Crawford D, Dryden MJ, Symmans WF, Sahin A, Giordano SH, Pusztai L, Do KA, Mills GB, Hortobagyi GN, Meric-Bernstam F.

Ann Oncol. 2014 Jun;25(6):1122-7. doi: 10.1093/annonc/mdu124. Epub 2014 Mar 24.

PMID:
24669015
[PubMed - in process]
19.

YB-1 transforms human mammary epithelial cells through chromatin remodeling leading to the development of basal-like breast cancer.

Davies AH, Reipas KM, Pambid MR, Berns R, Stratford AL, Fotovati A, Firmino N, Astanehe A, Hu K, Maxwell C, Mills GB, Dunn SE.

Stem Cells. 2014 Jun;32(6):1437-50. doi: 10.1002/stem.1707.

PMID:
24648416
[PubMed - in process]
20.

Concordance of genomic alterations between primary and recurrent breast cancer.

Meric-Bernstam F, Frampton GM, Ferrer-Lozano J, Yelensky R, Pérez-Fidalgo JA, Wang Y, Palmer GA, Ross JS, Miller VA, Su X, Eroles P, Barrera JA, Burgues O, Lluch AM, Zheng X, Sahin A, Stephens PJ, Mills GB, Cronin MT, Gonzalez-Angulo AM.

Mol Cancer Ther. 2014 May;13(5):1382-9. doi: 10.1158/1535-7163.MCT-13-0482. Epub 2014 Mar 7.

PMID:
24608573
[PubMed - in process]

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