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Diabetes and Insulin Therapy, but Not Metformin, Are Related to Hepatocellular Cancer Risk.

Miele L, Bosetti C, Turati F, Rapaccini G, Gasbarrini A, La Vecchia C, Boccia S, Grieco A.

Gastroenterol Res Pract. 2015;2015:570356. doi: 10.1155/2015/570356. Epub 2015 May 13.


AKT and 14-3-3 regulate Notch4 nuclear localization.

Ramakrishnan G, Davaakhuu G, Chung WC, Zhu H, Rana A, Filipovic A, Green AR, Atfi A, Pannuti A, Miele L, Tzivion G.

Sci Rep. 2015 Mar 5;5:8782. doi: 10.1038/srep08782.


The effect of CYP, GST, and SULT polymorphisms and their interaction with smoking on the risk of hepatocellular carcinoma.

Boccia S, Miele L, Panic N, Turati F, Arzani D, Cefalo C, Amore R, Bulajic M, Pompili M, Rapaccini G, Gasbarrini A, La Vecchia C, Grieco A.

Biomed Res Int. 2015;2015:179867. doi: 10.1155/2015/179867. Epub 2015 Jan 14.


Notch1 phenotype and clinical stage progression in non-small cell lung cancer.

Nguyen D, Rubinstein L, Takebe N, Miele L, Tomaszewski JE, Ivy P, Doroshow JH, Yang SX.

J Hematol Oncol. 2015 Feb 6;8(1):9. doi: 10.1186/s13045-014-0104-2.


Hepatocellular carcinoma treated by conventional transarterial chemoembolization in field-practice: serum sodium predicts survival.

Biolato M, Miele L, Vero V, Racco S, Di Stasi C, Iezzi R, Zanché A, Pompili M, Rapaccini GL, La Torre G, Gasbarrini A, Grieco A.

World J Gastroenterol. 2014 Jul 7;20(25):8158-65. doi: 10.3748/wjg.v20.i25.8158.


Sunitinib significantly suppresses the proliferation, migration, apoptosis resistance, tumor angiogenesis and growth of triple-negative breast cancers but increases breast cancer stem cells.

Chinchar E, Makey KL, Gibson J, Chen F, Cole SA, Megason GC, Vijayakumar S, Miele L, Gu JW.

Vasc Cell. 2014 Jun 1;6:12. doi: 10.1186/2045-824X-6-12. eCollection 2014.


NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome.

Shin HM, Tilahun ME, Cho OH, Chandiran K, Kuksin CA, Keerthivasan S, Fauq AH, Golde TE, Miele L, Thome M, Osborne BA, Minter LM.

Front Immunol. 2014 May 26;5:249. doi: 10.3389/fimmu.2014.00249. eCollection 2014.


Hyper-activation of Notch3 amplifies the proliferative potential of rhabdomyosarcoma cells.

De Salvo M, Raimondi L, Vella S, Adesso L, Ciarapica R, Verginelli F, Pannuti A, Citti A, Boldrini R, Milano GM, Cacchione A, Ferrari A, Collini P, Rosolen A, Bisogno G, Alaggio R, Inserra A, Locatelli M, Stifani S, Screpanti I, Miele L, Locatelli F, Rota R.

PLoS One. 2014 May 5;9(5):e96238. doi: 10.1371/journal.pone.0096238. eCollection 2014.


Uteroglobin, a possible ligand of the lipoxin receptor inhibits serum amyloid A-driven inflammation.

Antico G, Aloman M, Lakota K, Miele L, Fiore S, Sodin-Semrl S.

Mediators Inflamm. 2014;2014:876395. doi: 10.1155/2014/876395. Epub 2014 Mar 23.


Adenosine limits the therapeutic effectiveness of anti-CTLA4 mAb in a mouse melanoma model.

Iannone R, Miele L, Maiolino P, Pinto A, Morello S.

Am J Cancer Res. 2014 Mar 1;4(2):172-81. eCollection 2014.


Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells.

Dongre A, Surampudi L, Lawlor RG, Fauq AH, Miele L, Golde TE, Minter LM, Osborne BA.

Front Immunol. 2014 Feb 12;5:54. doi: 10.3389/fimmu.2014.00054. eCollection 2014.


Targeting Met and Notch in the Lfng-deficient, Met-amplified triple-negative breast cancer.

Zhang S, Chung WC, Miele L, Xu K.

Cancer Biol Ther. 2014 May;15(5):633-42. doi: 10.4161/cbt.28180. Epub 2014 Feb 20.


Glucokinase regulatory protein gene polymorphism affects liver fibrosis in non-alcoholic fatty liver disease.

Petta S, Miele L, Bugianesi E, Cammà C, Rosso C, Boccia S, Cabibi D, Di Marco V, Grimaudo S, Grieco A, Pipitone RM, Marchesini G, Craxì A.

PLoS One. 2014 Feb 3;9(2):e87523. doi: 10.1371/journal.pone.0087523. eCollection 2014. Erratum in: PLoS One. 2014;9(3):e92497.


Assessing needs and assets for building a regional network infrastructure to reduce cancer related health disparities.

Wells KJ, Lima DS, Meade CD, Muñoz-Antonia T, Scarinci I, McGuire A, Gwede CK, Pledger WJ, Partridge E, Lipscomb J, Matthews R, Matta J, Flores I, Weiner R, Turner T, Miele L, Wiese TE, Fouad M, Moreno CS, Lacey M, Christie DW, Price-Haywood EG, Quinn GP, Coppola D, Sodeke SO, Green BL, Lichtveld MY; Region 3 GMaP/BMaP investigators.

Eval Program Plann. 2014 Jun;44:14-25. doi: 10.1016/j.evalprogplan.2013.12.003. Epub 2013 Dec 26.


Sirt2 deacetylase is a novel AKT binding partner critical for AKT activation by insulin.

Ramakrishnan G, Davaakhuu G, Kaplun L, Chung WC, Rana A, Atfi A, Miele L, Tzivion G.

J Biol Chem. 2014 Feb 28;289(9):6054-66. doi: 10.1074/jbc.M113.537266. Epub 2014 Jan 20.


A case-control study on the effect of metabolic gene polymorphisms, nutrition, and their interaction on the risk of non-alcoholic fatty liver disease.

Miele L, Dall'armi V, Cefalo C, Nedovic B, Arzani D, Amore R, Rapaccini G, Gasbarrini A, Ricciardi W, Grieco A, Boccia S.

Genes Nutr. 2014 Mar;9(2):383. doi: 10.1007/s12263-013-0383-1. Epub 2014 Jan 9.


Tumor necrosis factor-α inhibitors and chronic hepatitis C: a comprehensive literature review.

Pompili M, Biolato M, Miele L, Grieco A.

World J Gastroenterol. 2013 Nov 28;19(44):7867-73. doi: 10.3748/wjg.v19.i44.7867. Review.


Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway.

Wu Q, Wang R, Yang Q, Hou X, Chen S, Hou Y, Chen C, Yang Y, Miele L, Sarkar FH, Chen Y, Wang Z.

Oncotarget. 2013 Nov;4(11):1999-2009.

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